Petra Gisela Helen Louis

Dr

    • AB25 2ZD

    • 9575 Citations
    19942019
    If you made any changes in Pure these will be visible here soon.

    Research Output 1994 2019

    Filter
    Article
    2019
    1 Citation (Scopus)
    6 Downloads (Pure)
    Open Access
    File
    formic acid
    Ruminococcus bromii
    formates
    coculture
    Coculture Techniques
    1 Citation (Scopus)

    Randomised clinical trial: Bifidobacterium lactis NCC2818 probiotic vs placebo, and impact on gut transit time, symptoms, and gut microbiology in chronic constipation

    Dimidi, E., Zdanaviciene, A., Christodoulides, S., Taheri, S., Louis, P., Duncan, P. I., Emami, N., Crabbé, R., De Castro, C. A., McLean, P., Bergonzelli, G. E., Whelan, K. & Mark Scott, S., 28 Feb 2019, In : Alimentary Pharmacology & Therapeutics. 49, 3, p. 251-264 14 p.

    Research output: Contribution to journalArticle

    Probiotics
    Constipation
    Microbiology
    Randomized Controlled Trials
    Placebos
    2 Citations (Scopus)
    4 Downloads (Pure)

    The effect of prunes on stool output, gut transit time and gastrointestinal microbiota: a randomised controlled trial

    Lever, E., Scott, S. M., Louis, P., Emery, P. W. & Whelan, K., Feb 2019, In : Clinical Nutrition. 38, 1, p. 165-173 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Volatile Fatty Acids
    Randomized Controlled Trials
    Weights and Measures
    Water
    Flatulence
    2018
    2 Citations (Scopus)
    2 Downloads (Pure)

    Dietary fibers inhibit obesity in mice, but host responses in the cecum and liver appear unrelated to fiber-specific changes in cecal bacterial taxonomic composition

    Drew, J. E., Reichardt, N., Williams, L. M., Mayer, C-D., Walker, A. W., Farquharson, A. J., Kastora, S., Farquharson, F., Milligan, G., Morrison, D. J., Preston, T., Flint, H. J. & Louis, P., 22 Oct 2018, In : Scientific Reports. 8, 15566.

    Research output: Contribution to journalArticle

    Open Access
    File
    Inulin
    Cecum
    Dietary Fiber
    Obesity
    Esters
    1 Citation (Scopus)
    7 Downloads (Pure)

    microPop: modelling microbial populations and communities in R

    Kettle, H., Holtrop, G., Louis, P. G. H. & Flint, H. J., Feb 2018, In : Methods in Ecology and Evolution. 9, 2, p. 399-409 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    functional group
    parameter uncertainty
    bacteriophage
    ecosystem function
    dynamic models
    3 Citations (Scopus)
    3 Downloads (Pure)

    Mutual Interaction of Phenolic Compounds and Microbiota: Metabolism of Complex Phenolic Apigenin-C- and Kaempferol-O-Derivatives by Human Fecal Samples

    Vollmer, M., Esders, S., Farquharson, F. M., Neugart, S., Duncan, S., Schreiner, M., Louis, P., Maul, R. & Rohn, S., 17 Jan 2018, In : Journal of Agricultural and Food Chemistry. 66, 2, p. 485–497 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Apigenin
    apigenin
    Microbiota
    kaempferol
    Metabolism
    3 Citations (Scopus)
    6 Downloads (Pure)

    Porcine small and large intestinal microbiota rapidly hydrolyze the masked mycotoxin deoxynivalenol-3-glucoside and release deoxynivalenol in spiked batch cultures in vitro

    Gratz, S., Currie, V., Richardson, A., Duncan, G., Holtrop, G., Farquharson, F., Louis, P., Pinton, P. & Oswald, I. P., Jan 2018, In : Applied and Environmental Microbiology. 84, 2, p. 1-9 9 p., 02106-17.

    Research output: Contribution to journalArticle

    Open Access
    File
    deoxynivalenol-3-glucoside
    Batch Cell Culture Techniques
    Mycotoxins
    deoxynivalenol
    intestinal microorganisms
    13 Citations (Scopus)
    8 Downloads (Pure)

    Specific substrate-driven changes in human faecal microbiota composition contrast with functional redundancy in short-chain fatty acid production

    Reichardt, N., Vollmer, M., Holtrop, G., Farquharson, F. M., Wefers, D., Bunzel, M., Duncan, S. H., Drew, J. E., Williams, L. M., Milligan, G., Preston, T., Morrison, D., Flint, H. J. & Louis, P., 2018, In : The ISME Journal. 12, p. 610-622 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Volatile Fatty Acids
    Butyrates
    Microbiota
    short chain fatty acids
    butyrates
    10 Citations (Scopus)
    9 Downloads (Pure)

    Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii

    Mukhopadhya, I., Morais, S., Laverde-Gomez, J., Sheridan, P. O., Walker, A. W., Kelly, W., Klieve, A. V., Ouwerkerk, D., Duncan, S. H., Louis, P., Koropatkin, N., Cockburn, D., Kibler, R., Cooper, P. J., Sandoval, C., Crost, E., Juge, N., Bayer, E. A. & Flint, H. J., Jan 2018, In : Environmental Microbiology. 20, p. 324-336 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Ruminococcus bromii
    Ruminococcus
    sporulation
    Rumen
    starch
    2017
    5 Citations (Scopus)
    3 Downloads (Pure)

    Chlorogenic acid versus amaranth's caffeoylisocitric acid – Gut microbial degradation of caffeic acid derivatives

    Vollmer, M., Schröter, D., Esders, S., Neugart, S., Farquharson, F. M., Duncan, S. H., Schreiner, M., Louis, P., Maul, R. & Rohn, S., Oct 2017, In : Food Research International. 100, 3, p. 375-384 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Chlorogenic Acid
    caffeic acid
    chlorogenic acid
    biodegradation
    intestinal microorganisms
    81 Citations (Scopus)
    3 Downloads (Pure)

    Diet Low in FODMAPs Reduces Symptoms in Patients with Irritable Bowel Syndrome and Probiotic Restores Bifidobacterium Species: a Randomized Controlled Trial

    Staudacher, HM., Lomer, MCE., Farquharson, FM., Louis, P., Fava, F., Franciosi, E., Scholz, M., Tuohy, KM., Lindsay, J. O., Irving, PM. & Whelan, K., Oct 2017, In : Gastroenterology. 153, 4, p. 936-947 12 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Bifidobacterium
    Irritable Bowel Syndrome
    Probiotics
    Randomized Controlled Trials
    Diet
    21 Citations (Scopus)
    6 Downloads (Pure)

    Prebiotic potential of pectin and pectic oligosaccharides to promote anti-inflammatory commensal bacteria in the human colon

    Chung, W. S. F., Meijerink, M., Zeuner, B., Holck, J., Louis, P., Meyer, A. S., Wells, J. M., Flint, H. J. & Duncan, S. H., 1 Nov 2017, In : FEMS Microbiology Ecology. 93, 11, p. 1-9 9 p., fix127.

    Research output: Contribution to journalArticle

    Open Access
    File
    Prebiotics
    commensal
    Oligosaccharides
    Colon
    Anti-Inflammatory Agents
    2016
    13 Citations (Scopus)
    7 Downloads (Pure)

    Extending colonic mucosal microbiome analysis - Assessment of colonic lavage as a proxy for endoscopic colonic biopsies

    Watt, E., Gemmell, M. R., Berry, S., Glaire, M., Farquharson, F., Louis, P., Murray, G. I., El-Omar, E. & Hold, G. L., 25 Nov 2016, In : Microbiome. 4, 61.

    Research output: Contribution to journalArticle

    Open Access
    File
    Therapeutic Irrigation
    Microbiota
    Proxy
    Biopsy
    Colonoscopy
    96 Citations (Scopus)
    5 Downloads (Pure)

    Modulation of the human gut microbiota by dietary fibres occurs at the species level

    Chung, W. S. F., Walker, A. W., Louis, P., Parkhill, J., Vermeiren, J., Bosscher, D., Duncan, S. H. & Flint, H. J., 11 Jan 2016, In : BMC Biology. 14, 3.

    Research output: Contribution to journalArticle

    Open Access
    File
    Inulin
    Dietary Fiber
    intestinal microorganisms
    Prebiotics
    inulin
    2015
    9 Citations (Scopus)

    Essential oils have different effects on human pathogenic and commensal bacteria in mixed faecal fermentations compared to pure cultures

    Thapa, D., Louis, P., Losa, R., Zweifel, B. & Wallace, R. J., 1 Feb 2015, In : Microbiology . 161, 2, p. 441-449 9 p.

    Research output: Contribution to journalArticle

    Thymol
    Volatile Oils
    Clostridium difficile
    Fermentation
    Bacteria
    42 Citations (Scopus)
    3 Downloads (Pure)

    Modelling the emergent dynamics and major metabolites of the human colonic microbiota

    Kettle, H., Louis, P. G. H., Holtrop, G., Duncan, S. H. & Flint, H. J., May 2015, In : Environmental Microbiology. 17, 5, p. 1615-1630 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Microbiota
    metabolite
    Colon
    metabolites
    colon
    43 Citations (Scopus)
    4 Downloads (Pure)

    Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii

    Ze, X., David, B., Laverde Gomez, J., Dassa, B., Sheridan, P. O., Duncan, S. H., Louis, P. G. H., Henrissat, B., Juge, N., Koropatkin, N. M., Bayer, E. A. & Flint, H. J., 29 Sep 2015, In : mBio. 6, 5, e01058-15.

    Research output: Contribution to journalArticle

    Open Access
    File
    Ruminococcus
    Amylases
    Starch
    Bacteria
    Proteins
    2014
    51 Citations (Scopus)

    Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings

    Hedin, C. R., McCarthy, N. E., Louis, P., Farquharson, F. M., McCartney, S., Taylor, K., Prescott, N. J., Murrells, T., Stagg, A. J., Whelan, K. & Lindsay, J. O., Oct 2014, In : Gut. 63, 10, p. 1578-1586 9 p.

    Research output: Contribution to journalArticle

    Crohn Disease
    Siblings
    Blood Cells
    T-Lymphocytes
    Phenotype
    22 Citations (Scopus)
    Ruminococcus
    Firmicutes
    Glucans
    Microbiota
    glucans
    157 Citations (Scopus)

    Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men

    Salonen, A., Lahti, L., Salojärvi, J., Holtrop, G., Korpela, K., Duncan, S. H., Date, P., Farquharson, F., Johnstone, A. M., Lobley, G. E., Louis, P., Flint, H. J. & de Vos, W. M., Nov 2014, In : The ISME Journal. 8, 11, p. 2218-2230 13 p.

    Research output: Contribution to journalArticle

    individual variation
    intestinal microorganisms
    Microbiota
    Fermentation
    fermentation
    215 Citations (Scopus)

    Phylogenetic distribution of three pathways for propionate production within the human gut microbiota

    Reichardt, N., Duncan, S. H., Young, P., Belenguer, A., McWilliam Leitch, C., Scott, K. P., Flint, H. J. & Louis, P., Jun 2014, In : The ISME Journal. 8, 6, p. 1323-1335 13 p.

    Research output: Contribution to journalArticle

    Propionates
    propionates
    intestinal microorganisms
    Coprococcus catus
    phylogenetics
    113 Citations (Scopus)
    3 Downloads (Pure)

    The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing

    Kennedy, N. A., Walker, A. W., Berry, S. H., Duncan, S. H., Farquarson, F. M., Louis, P., Thomson, J. M., Satsangi, J., Flint, H. J., Parkhill, J., Lees, C. W., Hold, G. L. & UK IBD Genetics Consortium, 24 Feb 2014, In : PloS ONE. 9, 2, e88982.

    Research output: Contribution to journalArticle

    Open Access
    File
    Bacterial Structures
    rRNA Genes
    intestinal microorganisms
    bacterial communities
    Genes
    2013
    45 Citations (Scopus)
    5 Downloads (Pure)

    Some are more equal than others: the role of ‘keystone’ species in the degradation of recalcitrant substrates

    Ze, X., Le Mougen, F., Duncan, S. H., Louis, P. & Flint, H. J., May 2013, In : Gut Microbes. 4, 3, p. 236-240 5 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Starch
    Ruminococcus
    Bacteria
    Large Intestine
    Rumen
    2012
    146 Citations (Scopus)
    4 Downloads (Pure)

    Microbiota of De-Novo Pediatric IBD: Increased Faecalibacterium Prausnitzii and Reduced Bacterial Diversity in Crohn's But Not in Ulcerative Colitis

    Hansen, R., Russell, R. K., Reiff, C., Louis, P., McIntosh, F., Berry, S. H., Mukhopadhya, I., Bisset, W. M., Barclay, A. R., Bishop, J., Flynn, D. M., McGrogan, P., Loganathan, S., Mahdi, G., Flint, H. J., El-Omar, E. M. & Hold, G. L., 5 Dec 2012, In : American journal of gastroenterology. 107, 12, p. 1913-1922 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Microbiota
    Ulcerative Colitis
    Inflammatory Bowel Diseases
    Crohn Disease
    Pediatrics
    36 Citations (Scopus)

    Phylogenetic distribution of genes encoding β-glucuronidase activity in human colonic bacteria and the impact of diet on faecal glycosidase activities

    McIntosh, F. M., Maison, N., Holtrop, G., Young, P., Stevens, V. J., Ince, J., Johnstone, A. M., Lobley, G., Flint, H. J. & Louis, P., 2012, In : Environmental Microbiology. 14, 8, p. 1876-1887 12 p.

    Research output: Contribution to journalArticle

    glycosidases
    Glycoside Hydrolases
    Glucuronidase
    Human Activities
    diet
    260 Citations (Scopus)

    Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon

    Ze, X., Duncan, S. H., Louis, P. & Flint, H. J., 2012, In : The ISME Journal. 6, 8, p. 1535-1543 9 p.

    Research output: Contribution to journalArticle

    Ruminococcus bromii
    Ruminococcus
    keystone species
    resistant starch
    starch
    2011
    41 Citations (Scopus)

    Butyrate production in phylogenetically diverse Firmicutes isolated from the chicken caecum

    Eeckhaut, V., Van Immerseel, F., Croubels, S., De Baere, S., Haesebrouck, F., Ducatelle, R., Louis, P. & Vandamme, P., Jul 2011, In : Microbial Biotechnology. 4, 4, p. 503-512 10 p.

    Research output: Contribution to journalArticle

    670 Citations (Scopus)

    Dominant and diet-responsive groups of bacteria within the human colonic microbiota

    Walker, A. W., Ince, J., Duncan, S. H., Webster, L., Holtrop, G., Ze, X., Brown, D., Stares, M. D., Scott, P., Bergerat, A., Louis, P., McIntosh, F., Johnstone, A. M., Lobley, G. E., Parkhill, J. & Flint, H. J., Feb 2011, In : The ISME Journal. 5, 2, p. 220-230 11 p.

    Research output: Contribution to journalArticle

    2010
    214 Citations (Scopus)
    2009
    379 Citations (Scopus)

    Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii

    Ramirez-Farias, C., Slezak, K., Fuller, Z., Duncan, A. S., Holtrop, G. & Louis, P., 28 Feb 2009, In : British Journal of Nutrition. 101, 4, p. 541-550 10 p.

    Research output: Contribution to journalArticle

    235 Citations (Scopus)

    The role of pH in determining the species composition of the human colonic microbiota

    Duncan, S. H., Louis, P., Thomson, J. M. & Flint, H. J., Aug 2009, In : Environmental Microbiology. 11, 8, p. 2112-2122 11 p.

    Research output: Contribution to journalArticle

    2008
    37 Citations (Scopus)

    Butyricicoccus pullicaecorum gen. nov., sp. nov., an anaerobic, butyrate-producing bacterium isolated from the caecal content of a broiler chicken

    Eeckhaut, V., Van Immerseel, F., Teirlynck, E., Pasmans, F., Fievez, V., Snauwaert, C., Haesebrouck, F., Ducatelle, R., Louis, P. & Vandamme, P., Dec 2008, In : International Journal of Systematic and Evolutionary Microbiology. 58, 12, p. 2799-2802 4 p.

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Changes in the mucosally adherent microbial community in ulcerative colitis

    Thomson, J. M., Louis, P., Hold, G. L., Mowat, N. G., Flint, H. J. & El-Omar, E. M., Jan 2008, In : Gut. 57, Supplement 1, p. A150-A150 1 p.

    Research output: Contribution to journalArticle

    97 Citations (Scopus)

    Distribution of β-glucosidase and β-glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria

    Dabek, M., McCrae, S. I., Stevens, V. J., Duncan, S. H. & Louis, P., Dec 2008, In : FEMS Microbiology Ecology. 66, 3, p. 487-495 9 p.

    Research output: Contribution to journalArticle

    33 Citations (Scopus)
    3 Downloads (Pure)

    Heterologous ectoine production in Escherichia coli: By-passing the metabolic bottle-neck

    Bestaver, T., Louis, P. & Galinski, E. A., 29 Aug 2008, In : Saline Systems. 4, 12.

    Research output: Contribution to journalArticle

    Open Access
    File
    bottles
    neck
    Neck
    Escherichia coli
    gene
    603 Citations (Scopus)

    Human colonic microbiota associated with diet, obesity and weight loss

    Duncan, S. H., Lobley, G., Holtrop, G., Ince, J., Johnstone, A., Louis, P. & Flint, H. J., Nov 2008, In : International Journal of Obesity. 32, 11, p. 1720-1724 5 p.

    Research output: Contribution to journalArticle

    32 Citations (Scopus)

    Influence of cabbage processing methods and prebiotic manipulation of colonic microflora on glucosinolate breakdown in man

    Fuller, Z., Louis, P., Mihajlovski, A., Rungapamestry, V., Ratcliffe, B. & Duncan, A. J., Aug 2007, In : British Journal of Nutrition. 98, 2, p. 364-372 9 p.

    Research output: Contribution to journalArticle

    Glucosinolates
    Prebiotics
    Brassica
    Bifidobacterium
    Inulin
    28 Citations (Scopus)

    Organization of butyrate synthetic genes in human colonic bacteria: phylogenetic conservation and horizontal gene transfer

    Louis, P., McCrae, S. I., Charrier, C. & Flint, H. J., Apr 2007, In : FEMS Microbiology Letters. 269, 2, p. 240-247 8 p.

    Research output: Contribution to journalArticle

    85 Citations (Scopus)

    Relation between phylogenetic position, lipid metabolism and butyrate production by different Butyrivibrio-like bacteria from the rumen

    Paillard, D., McKain, N., Chaudhary, L. C., Walker, N. D., Pizette, F., Koppova, I., McEwan, N. R., Kopecny, J., Vercoe, P. E., Louis, P. & Wallace, R. J., May 2007, In : Antonie van Leeuwenhoek . 91, 4, p. 417-422 6 p.

    Research output: Contribution to journalArticle

    2006
    45 Citations (Scopus)
    14 Downloads (Pure)

    A novel class of CoA-transferase involved in short-chain fatty acid metabolism in butyrate-producing human colonic bacteria

    Charrier, C., Duncan, G. J., Reid, M. D., Rucklidge, G. J., Henderson, D., Young, P., Russell, V. J., Aminov, R. I., Flint, H. J. & Louis, P., Jan 2006, In : Microbiology . 152, 1, p. 179-185 7 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    350 Citations (Scopus)

    Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut

    Belenguer, A., Duncan, S. H., Calder, A. G., Holtrop, G., Louis, P., Lobley, G. & Flint, H. J., 1 May 2006, In : Applied and Environmental Microbiology. 72, 5, p. 3593-3599 7 p.

    Research output: Contribution to journalArticle

    Bifidobacterium adolescentis
    anaerobes
    Butyrates
    butyrates
    Eubacterium hallii
    2004
    431 Citations (Scopus)
    176 Citations (Scopus)

    Restricted distribution of the butyrate kinase pathway among butyrate-producing bacteria from the human colon

    Louis, P., Duncan, S. H., McCrae, S. I., Millar, J., Jackson, M. S. & Flint, H. J., Apr 2004, In : Journal of Bacteriology. 186, 7, p. 2099-2106 8 p.

    Research output: Contribution to journalArticle

    2003
    75 Citations (Scopus)

    A role for mechanosensitive channels in survival of stationary phase: regulation of channel expression by RpoS

    Stokes, N. R., Murray, H. D., Subramaniam, C., Gourse, R. L., Louis, P., Bartlett, W., Miller, S. & Booth, I. R., 23 Dec 2003, In : PNAS. 100, 26, p. 15959-15964 6 p.

    Research output: Contribution to journalArticle

    1999
    455 Citations (Scopus)

    Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels: identification of genes required for MscS activity

    Levina, N., Totemeyer, S., Stokes, N. R., Louis, P., Jones, M. A. & Booth, I. R., 1999, In : EMBO Journal. 18, p. 1730-1737 8 p.

    Research output: Contribution to journalArticle

    1997
    121 Citations (Scopus)
    3 Citations (Scopus)

    Identification of plasmids in the genus Marinococcus and complete nucleotide sequence of plasmid pPL1 from Marinococcus halophilus

    Louis, P. & Galinski, E. A., 1997, In : Plasmid. 38, 2, p. 107-114 8 p.

    Research output: Contribution to journalArticle

    1994
    67 Citations (Scopus)

    SURVIVAL OF ESCHERICHIA-COLI DURING DRYING AND STORAGE IN THE PRESENCE OF COMPATIBLE SOLUTES

    LOUIS, P., TRUPER, H. G. & GALINSKI, E. A., Aug 1994, In : Applied Microbiology and Biotechnology. 41, 6, p. 684-688 5 p.

    Research output: Contribution to journalArticle