• 580 Citations
20052020

Research output per year

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Research Output

2020

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

The Future Ready Ideas Lab: Future proofing bioscience students enterprise skills

Barrow, J., Perkins, J., Marini, P. & Davidson, A., 2020, (Accepted/In press) In : Journal of Learning and Teaching.

Research output: Contribution to journalArticle

2019

Culturing Enterprise Skills in Bioscience Students

Davidson, A., Gardiner, M., Perkins, J., Marini, P. & Barrow, J., 8 Jul 2019.

Research output: Contribution to conferencePoster

Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

Khatib, T., Marini, P., Nunna, S., Chisholm, D. R., Whiting, A., Redfern, C., Greig, I. R. & McCaffery, P., 2 May 2019, In : Cell Communication and Signaling. 17, 16 p., 40.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
7 Downloads (Pure)
2018

Widening access to students from remote and rural backgrounds

Marini, P., Cleland, J., Davies, S., Denison, A., Dollery, W., Fraser, D., Susan, G., Johnston, A., Kay, C., Miller, S., Patey, R. & Smith, G., 30 Apr 2018.

Research output: Contribution to conferencePoster

2017

An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome

Hay, E. A., Khalaf, A. R., Marini, P., Brown, A., Heath, K., Sheppard, D. & MacKenzie, A., Aug 2017, In : Neuropeptides. 64, p. 101-107 7 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
6 Downloads (Pure)

The pharmacology and therapeutic potential of plant cannabinoids

Cascio, M. G., Pertwee, R. G. & Marini, P., 2017, Cannabis sativa L. - Botany and Biotechnology. Chandra, S., Lata, H. & ElSohly, M. A. (eds.). Springer, Biomedicine & Life Sciences, p. 207-225 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)
2016

The Cyclic AMP Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells

Marini, P., Cascio, M. G. & Pertwee, R. G., 2016, Endocannabinoid Signaling: Methods and Protocols. Maccarrone, M. (ed.). New York: Springer Science+Business Media, p. 85-93 9 p. (Methods in Molecular Biology; vol. 1412).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

The Displacement Binding Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells

Cascio, M. G., Marini, P. & Pertwee, R. G., 1 Jun 2016, Endocannabinoid Signaling: Methods and Protocols. Maccarrone, M. (ed.). Springer Science+Business Media, Vol. 1412. p. 57-63 7 p. (Methods in Molecular Biology; vol. 1412).

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

A1-adenosine acute withdrawal response and cholecystokinin-8 induced contractures are regulated by Ca2+- and ATP-activated K+ channels

Cascio, M. G., Valeri, D., Tucker, S. J. & Marini, P., May 2015, In : Pharmacological Research. 95-96, p. 82-91 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
3 Downloads (Pure)

Biosynthesis and fate of endocannabinoids

Cascio, M. G. & Marini, P., 2015, Endocanabinoids: Handbook of Experimental Pharmacology. Pertwee, R. G. (ed.). Springer-Verlag, Vol. 231. p. 39-58 10 p. (Handbook of Experimental Pharmacology).

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Citations (Scopus)

CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency

Smoum, R., Baraghithy, S., Chourasia, M., Breuer, A., Mussai, N., Attar-Namdar, M., Kogan, N. M., Raphael, B., Bolognini, D., Cascio, M. G., Marini, P., Pertwee, R. G., Shurki, A., Mechoulam, R. & Bab, I., 14 Jul 2015, In : PNAS. 112, 28, p. 8774-8779 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects

Cascio, M. G., Zamberletti, E., Marini, P., Parolaro, D. & Pertwee, R. G., Mar 2015, In : British Journal of Pharmacology. 172, 5, p. 1305-1318 14 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
5 Downloads (Pure)
2014

Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist

Brizzi, A., Aiello, F., Marini, P., Cascio, M. G., Corelli, F., Brizzi, V., De Petrocellis, L., Ligresti, A., Luongo, L., Lamponi, S., Maione, S., Pertwee, R. G. & Di Marzo, V., 1 Sep 2014, In : Behavioral and Brain Sciences. 22, 17, p. 4770-4783 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1 Downloads (Pure)

The phytocannabinoid, Δ9-tetrahydrocannabivarin, can act trough 5HT1A receptors to produce anti-psychotic effects

Cascio, M. G., Zamberletti, E., Marini, P., Pertwee, R. G. & Parolaro, D., 29 Jun 2014.

Research output: Contribution to conferencePoster

2013

Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors

Marini, P., Cascio, M. G., King, A., Pertwee, R. G. & Ross, R. A., Jun 2013, In : British Journal of Pharmacology. 169, 4, p. 887-899 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2012

Biphasic regulation of the acute µ-withdrawal and CCk-8 contracture responses by the ORL-1 system in guinea pig ileum

Marini, P., Romanelli, L., Valeri, D., Cascio, M. G., Tucci, P., Valeri, P. & Palmery, M., Jan 2012, In : Pharmacological Research. 65, 1, p. 100-110 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The NOP receptor involvement in both withdrawal- and CCk-8-induced contracture responses of guinea pig isolated ileum after acute activation of k-opioid receptor

Marini, P., Romanelli, L., Valeri, D., Cascio, M. G., Tucci, P., Valeri, P. & Palmery, M., Dec 2012, In : Peptides. 38, 2, p. 418-426 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2010

Acute withdrawal induced by adenosine A-receptor activation in isolated guinea-pig ileum: role of opioid receptors and effect of cholecystokinin

Marini, P., Romanelli, L., Valeri, D., Tucci, P. & Palmery, M., May 2010, In : Journal of Pharmacy and Pharmacology. 62, 5, p. 622-632 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-α ligands in Zucker rats

Izzo, A. A., Piscitelli, F., Capasso, R., Marini, P., Cristino, L., Petrosino, S. & Di Marzo, V., Jan 2010, In : Obesity. 18, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Characterization of well-known ligands on tissues naturally expressing CB2 receptors

Marini, P. & Ross, R. A., 23 Jul 2010.

Research output: Contribution to conferencePoster

Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.

Pasquini, S., Ligresti, A., Mugnaini, C., Semeraro, T., Cicione, L., De Rosa, M., Guida, F., Luongo, L., De Chiaro, M., Cascio, M. G., Bolognini, D., Marini, P., Pertwee, R. G., Maione, S., Di Marzo, V. & Corelli, F., 26 Aug 2010, In : Journal of Medicinal Chemistry. 53, 16, p. 5915-5928 14 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

Bolognini, D., Costa, B., Maione, S., Comelli, F., Marini, P., Di Marzo, V., Parolaro, D., Ross, R. A., Gauson, L. A., Cascio, M. G. & Pertwee, R. G., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 677-687 11 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2009

Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors

Marini, P., Moriello, A. S., Cristino, L., Palmery, M., De Petrocellis, L. & Di Marzo, V., Jul 2009, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1793, 7, p. 1289-1303 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2008

CB1 receptor mobilization of intracellular calcium in SH-SY5y cells: coincident signalling with the Gq/11-coupled M3 muscarinic receptor and Gi/o-coupled d-opioid receptor

Marini, P., De Petrocellis, L., Schiano-Moriello, A., Palmery, M., Di Marzo, V. & Cristino, L., 2008.

Research output: Contribution to conferencePoster

Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors

Capasso, R., Borrelli, F., Cascio, M. G., Aviello, G., Huben, K., Zjawiony, J. K., Marini, P., Romano, B., Di Marzo, V., Capasso, F. & Izzo, A. A., Nov 2008, In : British Journal of Pharmacology. 155, 5, p. 681-689 9 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
1 Downloads (Pure)

Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8

De Petrocellis, L., Vellani, V., Schiano-Moriello, A., Marini, P., Magherini, P. C., Orlando, P. & Di Marzo, V., Jun 2008, In : Journal of Pharmacology and Experimental Therapeutics. 325, 3, p. 1007-1015 9 p.

Research output: Contribution to journalArticle

187 Citations (Scopus)
2007

Coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma ß-cells

Marini, P., De Petrocellis, L., Matias, I., Schiano-Moriello, A., Starowicz, K., Cristino, L. & Di Marzo, V., 2007.

Research output: Contribution to conferencePoster

Effect of 4-amynopyridine (4AP) and tetraethylamonium (TEA) on the expression of µ-opioid acute dependence in guinea pig ileum

Palmery, M., Martinoli, L., Marini, P., Ipavec, V., Fioravanti, A. & Valeri, P., 2007.

Research output: Contribution to conferencePoster

Functional activity of cannabinoid receptors in RIN-m5F insulinoma ß-cells: interactions with bombesin and vanilloid receptors.

Marini, P., De Petrocellis, L., Matias, I., Schiano-Moriello, A., Palmery, M., Starowicz, K., Cristino, L., Nigam, S. & Di Marzo, V., 2007.

Research output: Contribution to conferencePoster

Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells

De Petrocellis, L., Marini, P., Matias, I., Moriello, A. S., Starowicz, K., Cristino, L., Nigam, S. & Di Marzo, V., 15 Aug 2007, In : Experimental Cell Research. 313, 14, p. 2993-3004 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Regulation of intracellular calcium in insulinoma cells by bombesin and cannabinoids: same coupling for different informations?

Marini, P., De Petrocellis, L., Palmery, M., Schiano-Moriello, A., Matias, I. & Di Marzo, V., 2007.

Research output: Contribution to conferencePoster

2005

Withdrawal to acute adenosine A1 receptor activation: role of opioid and cannabinoid CB1 receptors.

Palmery, M., Martinoli, L., Marini, P., Amico, M. C., Fioravanti, A. & Valeri, P., 2005.

Research output: Contribution to conferencePoster