• 559 Citations
20052020

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2020

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In : Molecular Psychiatry.

Research output: Contribution to journalArticle

The Future Ready Ideas Lab: Future proofing bioscience students enterprise skills

Barrow, J., Perkins, J., Marini, P. & Davidson, A., 2020, (Accepted/In press) In : Journal of Learning and Teaching.

Research output: Contribution to journalArticle

2019

Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

Khatib, T., Marini, P., Nunna, S., Chisholm, D. R., Whiting, A., Redfern, C., Greig, I. R. & McCaffery, P., 2 May 2019, In : Cell Communication and Signaling. 17, 16 p., 40.

Research output: Contribution to journalArticle

Open Access
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6 Downloads (Pure)
2017

An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome

Hay, E. A., Khalaf, A. R., Marini, P., Brown, A., Heath, K., Sheppard, D. & MacKenzie, A., Aug 2017, In : Neuropeptides. 64, p. 101-107 7 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
6 Downloads (Pure)
2015

A1-adenosine acute withdrawal response and cholecystokinin-8 induced contractures are regulated by Ca2+- and ATP-activated K+ channels

Cascio, M. G., Valeri, D., Tucker, S. J. & Marini, P., May 2015, In : Pharmacological Research. 95-96, p. 82-91 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
3 Downloads (Pure)

CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency

Smoum, R., Baraghithy, S., Chourasia, M., Breuer, A., Mussai, N., Attar-Namdar, M., Kogan, N. M., Raphael, B., Bolognini, D., Cascio, M. G., Marini, P., Pertwee, R. G., Shurki, A., Mechoulam, R. & Bab, I., 14 Jul 2015, In : PNAS. 112, 28, p. 8774-8779 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects

Cascio, M. G., Zamberletti, E., Marini, P., Parolaro, D. & Pertwee, R. G., Mar 2015, In : British Journal of Pharmacology. 172, 5, p. 1305-1318 14 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
5 Downloads (Pure)
2014

Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist

Brizzi, A., Aiello, F., Marini, P., Cascio, M. G., Corelli, F., Brizzi, V., De Petrocellis, L., Ligresti, A., Luongo, L., Lamponi, S., Maione, S., Pertwee, R. G. & Di Marzo, V., 1 Sep 2014, In : Behavioral and Brain Sciences. 22, 17, p. 4770-4783 14 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
1 Downloads (Pure)
2013

Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors

Marini, P., Cascio, M. G., King, A., Pertwee, R. G. & Ross, R. A., Jun 2013, In : British Journal of Pharmacology. 169, 4, p. 887-899 13 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2012

Biphasic regulation of the acute µ-withdrawal and CCk-8 contracture responses by the ORL-1 system in guinea pig ileum

Marini, P., Romanelli, L., Valeri, D., Cascio, M. G., Tucci, P., Valeri, P. & Palmery, M., Jan 2012, In : Pharmacological Research. 65, 1, p. 100-110 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

The NOP receptor involvement in both withdrawal- and CCk-8-induced contracture responses of guinea pig isolated ileum after acute activation of k-opioid receptor

Marini, P., Romanelli, L., Valeri, D., Cascio, M. G., Tucci, P., Valeri, P. & Palmery, M., Dec 2012, In : Peptides. 38, 2, p. 418-426 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2010

Acute withdrawal induced by adenosine A-receptor activation in isolated guinea-pig ileum: role of opioid receptors and effect of cholecystokinin

Marini, P., Romanelli, L., Valeri, D., Tucci, P. & Palmery, M., May 2010, In : Journal of Pharmacy and Pharmacology. 62, 5, p. 622-632 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-α ligands in Zucker rats

Izzo, A. A., Piscitelli, F., Capasso, R., Marini, P., Cristino, L., Petrosino, S. & Di Marzo, V., Jan 2010, In : Obesity. 18, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.

Pasquini, S., Ligresti, A., Mugnaini, C., Semeraro, T., Cicione, L., De Rosa, M., Guida, F., Luongo, L., De Chiaro, M., Cascio, M. G., Bolognini, D., Marini, P., Pertwee, R. G., Maione, S., Di Marzo, V. & Corelli, F., 26 Aug 2010, In : Journal of Medicinal Chemistry. 53, 16, p. 5915-5928 14 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

Bolognini, D., Costa, B., Maione, S., Comelli, F., Marini, P., Di Marzo, V., Parolaro, D., Ross, R. A., Gauson, L. A., Cascio, M. G. & Pertwee, R. G., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 677-687 11 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2009

Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors

Marini, P., Moriello, A. S., Cristino, L., Palmery, M., De Petrocellis, L. & Di Marzo, V., Jul 2009, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1793, 7, p. 1289-1303 15 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2008

Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors

Capasso, R., Borrelli, F., Cascio, M. G., Aviello, G., Huben, K., Zjawiony, J. K., Marini, P., Romano, B., Di Marzo, V., Capasso, F. & Izzo, A. A., Nov 2008, In : British Journal of Pharmacology. 155, 5, p. 681-689 9 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)
1 Downloads (Pure)

Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8

De Petrocellis, L., Vellani, V., Schiano-Moriello, A., Marini, P., Magherini, P. C., Orlando, P. & Di Marzo, V., Jun 2008, In : Journal of Pharmacology and Experimental Therapeutics. 325, 3, p. 1007-1015 9 p.

Research output: Contribution to journalArticle

181 Citations (Scopus)
2007

Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells

De Petrocellis, L., Marini, P., Matias, I., Moriello, A. S., Starowicz, K., Cristino, L., Nigam, S. & Di Marzo, V., 15 Aug 2007, In : Experimental Cell Research. 313, 14, p. 2993-3004 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)