• 555 Citations
20052019
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Research Output 2005 2019

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Article
2019
4 Downloads (Pure)

Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

Khatib, T., Marini, P., Nunna, S., Chisholm, D. R., Whiting, A., Redfern, C., Greig, I. R. & McCaffery, P., 2 May 2019, In : Cell Communication and Signaling. 17, 16 p., 40.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylation
Retinoids
Tretinoin
Assays
Retinoic Acid Receptors
2017
10 Citations (Scopus)
5 Downloads (Pure)

An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome

Hay, E. A., Khalaf, A. R., Marini, P., Brown, A., Heath, K., Sheppard, D. & MacKenzie, A., Aug 2017, In : Neuropeptides. 64, p. 101-107 7 p.

Research output: Contribution to journalArticle

Open Access
File
Clustered Regularly Interspaced Short Palindromic Repeats
Gene Deletion
Neuropeptides
Guide RNA
Genome
2015
1 Citation (Scopus)
3 Downloads (Pure)

A1-adenosine acute withdrawal response and cholecystokinin-8 induced contractures are regulated by Ca2+- and ATP-activated K+ channels

Cascio, M. G., Valeri, D., Tucker, S. J. & Marini, P., May 2015, In : Pharmacological Research. 95-96, p. 82-91 10 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Contracture
Adenosine
Adenosine Triphosphate
Ileum
22 Citations (Scopus)

CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency

Smoum, R., Baraghithy, S., Chourasia, M., Breuer, A., Mussai, N., Attar-Namdar, M., Kogan, N. M., Raphael, B., Bolognini, D., Cascio, M. G., Marini, P., Pertwee, R. G., Shurki, A., Mechoulam, R. & Bab, I., 14 Jul 2015, In : PNAS. 112, 28, p. 8774-8779 6 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor Agonists
Cannabinoid Receptor CB2
Cannabinoid Receptor CB1
HU 308
Ligands
11 Citations (Scopus)
4 Downloads (Pure)

The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects

Cascio, M. G., Zamberletti, E., Marini, P., Parolaro, D. & Pertwee, R. G., Mar 2015, In : British Journal of Pharmacology. 172, 5, p. 1305-1318 14 p.

Research output: Contribution to journalArticle

Open Access
File
Serotonin 5-HT1 Receptors
Receptor, Serotonin, 5-HT1A
8-Hydroxy-2-(di-n-propylamino)tetralin
Antipsychotic Agents
Membranes
2014
5 Citations (Scopus)
1 Downloads (Pure)

Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist

Brizzi, A., Aiello, F., Marini, P., Cascio, M. G., Corelli, F., Brizzi, V., De Petrocellis, L., Ligresti, A., Luongo, L., Lamponi, S., Maione, S., Pertwee, R. G. & Di Marzo, V., 1 Sep 2014, In : Behavioral and Brain Sciences. 22, 17, p. 4770-4783 14 p.

Research output: Contribution to journalArticle

Monoacylglycerol Lipases
Ankyrins
Cannabinoid Receptors
Pharmacology
Cannabinoid Receptor CB2
2013
13 Citations (Scopus)

Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors

Marini, P., Cascio, M. G., King, A., Pertwee, R. G. & Ross, R. A., Jun 2013, In : British Journal of Pharmacology. 169, 4, p. 887-899 13 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB2
Cannabinoid Receptors
CHO Cells
Ligands
Spleen
23 Citations (Scopus)

Network-based target ranking for polypharmacological therapies

Vitali, F., Mulas, F., Marini, P. & Bellazzi, R., 2013, In : AMIA Joint Summits on Translational Science proceedings AMIA Summit on Translational Science. 2013, 168.

Research output: Contribution to journalArticle

Polypharmacology
Drug Discovery
Therapeutics
Type 2 Diabetes Mellitus
Pharmaceutical Preparations
2012
4 Citations (Scopus)

Biphasic regulation of the acute µ-withdrawal and CCk-8 contracture responses by the ORL-1 system in guinea pig ileum

Marini, P., Romanelli, L., Valeri, D., Cascio, M. G., Tucci, P., Valeri, P. & Palmery, M., Jan 2012, In : Pharmacological Research. 65, 1, p. 100-110 11 p.

Research output: Contribution to journalArticle

Opioid Receptors
Contracture
Ileum
Guinea Pigs
Opioid Analgesics
3 Citations (Scopus)

The NOP receptor involvement in both withdrawal- and CCk-8-induced contracture responses of guinea pig isolated ileum after acute activation of k-opioid receptor

Marini, P., Romanelli, L., Valeri, D., Cascio, M. G., Tucci, P., Valeri, P. & Palmery, M., Dec 2012, In : Peptides. 38, 2, p. 418-426 9 p.

Research output: Contribution to journalArticle

Opioid Receptors
Contracture
Ileum
Opioid Analgesics
Guinea Pigs
2010
6 Citations (Scopus)

Acute withdrawal induced by adenosine A-receptor activation in isolated guinea-pig ileum: role of opioid receptors and effect of cholecystokinin

Marini, P., Romanelli, L., Valeri, D., Tucci, P. & Palmery, M., May 2010, In : Journal of Pharmacy and Pharmacology. 62, 5, p. 622-632 11 p.

Research output: Contribution to journalArticle

Purinergic P1 Receptors
Cholecystokinin
Opioid Receptors
Ileum
Opioid Analgesics
45 Citations (Scopus)

Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-α ligands in Zucker rats

Izzo, A. A., Piscitelli, F., Capasso, R., Marini, P., Cristino, L., Petrosino, S. & Di Marzo, V., Jan 2010, In : Obesity. 18, 1, p. 55-62 8 p.

Research output: Contribution to journalArticle

Zucker Rats
Peroxisome Proliferator-Activated Receptors
Fasting
Ligands
Duodenum
30 Citations (Scopus)

Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.

Pasquini, S., Ligresti, A., Mugnaini, C., Semeraro, T., Cicione, L., De Rosa, M., Guida, F., Luongo, L., De Chiaro, M., Cascio, M. G., Bolognini, D., Marini, P., Pertwee, R. G., Maione, S., Di Marzo, V. & Corelli, F., 26 Aug 2010, In : Journal of Medicinal Chemistry. 53, 16, p. 5915-5928 14 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

Bolognini, D., Costa, B., Maione, S., Comelli, F., Marini, P., Di Marzo, V., Parolaro, D., Ross, R. A., Gauson, L. A., Cascio, M. G. & Pertwee, R. G., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 677-687 11 p.

Research output: Contribution to journalArticle

2009
20 Citations (Scopus)

Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors

Marini, P., Moriello, A. S., Cristino, L., Palmery, M., De Petrocellis, L. & Di Marzo, V., Jul 2009, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1793, 7, p. 1289-1303 15 p.

Research output: Contribution to journalArticle

Cannabinoid Receptor CB1
delta Opioid Receptor
Opioid Receptors
Neuroblastoma
Muscarinic M3 Receptors
2008
62 Citations (Scopus)
1 Downloads (Pure)

Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors

Capasso, R., Borrelli, F., Cascio, M. G., Aviello, G., Huben, K., Zjawiony, J. K., Marini, P., Romano, B., Di Marzo, V., Capasso, F. & Izzo, A. A., Nov 2008, In : British Journal of Pharmacology. 155, 5, p. 681-689 9 p.

Research output: Contribution to journalArticle

salvinorin A
Ileitis
Salvia
Cannabinoids
Opioid Analgesics
172 Citations (Scopus)

Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8

De Petrocellis, L., Vellani, V., Schiano-Moriello, A., Marini, P., Magherini, P. C., Orlando, P. & Di Marzo, V., Jun 2008, In : Journal of Pharmacology and Experimental Therapeutics. 325, 3, p. 1007-1015 9 p.

Research output: Contribution to journalArticle

Cannabidiol
Ankyrins
Transient Receptor Potential Channels
Cannabinoids
Dronabinol
2007
52 Citations (Scopus)

Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells

De Petrocellis, L., Marini, P., Matias, I., Moriello, A. S., Starowicz, K., Cristino, L., Nigam, S. & Di Marzo, V., 15 Aug 2007, In : Experimental Cell Research. 313, 14, p. 2993-3004 11 p.

Research output: Contribution to journalArticle

Cannabinoid Receptors
Insulinoma
Phosphoinositide Phospholipase C
Cannabinoid Receptor CB1
Calcium