• 4886 Citations
1994 …2020

Research output per year

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Research Output

2020
Open Access

Is intrinsic lumbar spine shape associated with Lumbar Disc Degeneration? An exploratory study

Deane, J. A., Pavlova, A. V., Lim, A. K. P., Gregory, J. S., Aspden, R. M. & McGregor, A. H., 13 Apr 2020, (Accepted/In press) In : BMC Musculoskeletal Disorders.

Research output: Contribution to journalArticle

Motor development in infancy and spine shape in early old age: findings from a British birth cohort study

Saunders, F. R., Gregory, J. S., Pavlova, A., Muthuri, S. G., Hardy, R. J., Martin, K. R., Barr, R. J., Adams, J. E., Kuh, D., Aspden, R. M., Cooper, R. & Ireland, A., 18 Mar 2020, In : Journal of Orthopaedic Research. 9 p.

Research output: Contribution to journalArticle

Open Access

Sex differences in proximal femur shape: findings from a population-based study in adolescents

Frysz, M., Gregory, J., Aspden, R. M., Paternoster, L. & Tobias, J. H., 12 Mar 2020, In : Scientific Reports. 10, 4612.

Research output: Contribution to journalArticle

Open Access
File
2 Downloads (Pure)

Statistical shape modelling provides a responsive measure of morphological change in knee osteoarthritis over 12 months

Gregory, J. S., Barr, R. J., Yoshida, K., Alesci, S., Reid, D. M. & Aspden, R. M., 14 Jan 2020, In : Rheumatology.

Research output: Contribution to journalArticle

Open Access

The effect of pubertal timing, as reflected by height tempo, on proximal femur shape: findings from a population-based study in adolescents

Frysz, M., Gregory, J. S., Aspden, R. M., Paternoster, L. & Tobias, J. H., Feb 2020, In : Bone. 131, 8 p., 115179.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
3 Downloads (Pure)
2019

Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age

Ireland, A., Saunders, F. R., Muthuri, S. G., Pavlova, A., Hardy, R., Martin, K., Barr, R., Kuh, D., Aspden, R. M., Gregory, J. & Cooper, R., Mar 2019, In : Journal of Bone and Mineral Research. 34, 3, p. 455-463 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
10 Downloads (Pure)

Identification of Novel Loci Associated With Hip Shape: A Meta‐Analysis of Genomewide Association Studies

Baird, D. A., Evans, D. S., Kamanu, F. K., Gregory, J. S., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Aspden, R. M., Jenkins, D., Kiel, D. P., Orwoll, E. S., Cummings, S. R., Lane, N. E., Mullin, B. H., Williams, F. MK., Richards, J. B., Wilson, S. G., Spector, T. D., Faber, B. G., Lawlor, D. A. & 10 others, Grundberg, E., Ohlsson, C., Pettersson-Kymmer, U., Capellini, T. D., Richard, D., Beck, T. J., Evans, D. M., Paternoster, L., Karasik, D. & Tobias, J. H., Feb 2019, In : Journal of Bone and Mineral Research. 34, 2, p. 241-251 11 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
5 Downloads (Pure)

Osteoarthritis as an organ disease: from the cradle to the grave

Aspden, R. M. & Saunders, F., 30 Jan 2019, In : European Cells & Materials. 37, p. 74-87 14 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
7 Downloads (Pure)

Perinatal factors associate with vertebral size and shape but not lumbar lordosis in 10-year-old children

Pavlova, A., Jeffrey, J. E., Barr, R. J. & Aspden, R. M., Oct 2019, In : Journal of Anatomy. 235, 4, p. 749-756 8 p.

Research output: Contribution to journalArticle

Open Access
File
Open Access
File
3 Citations (Scopus)
13 Downloads (Pure)
2018

AGE AT ONSET OF WALKING IN INFANCY IS ASSOCIATED WITH HIP AND SPINE SHAPE IN EARLY OLD AGE

Ireland, A., Saunders, F., Muthuri, S., Pavlova, A., Hardy, R., Martin, K., Barr, R., Adams, J., Kuh, D., Aspden, R., Gregory, J. & Cooper, R., Dec 2018, In : Osteoporosis International. 29, Suppl. 2, p. 612-613 2 p.

Research output: Contribution to journalAbstract

Associations between back pain across adulthood and spine shape in early old age in a British birth cohort

Muthuri, S. G., Pavlova, A., Saunders, F. R., Hardy, R. J., Gregory, J. S., Barr, R. J., Martin, K. R., Adams, J. E., Kuh, D., Aspden, R. M. & Cooper, R., 5 Nov 2018, In : Scientific Reports. 8, 16309.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
7 Downloads (Pure)

Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: the Medical Research Council National Survey of Health and Development

Pavlova, A. V., Muthuri, S. G., Cooper, R., Saunders, F. R., Gregory, J. S., Barr, R., Martin, K. R., Adams, J. E., Kuh, D., Hardy, R. J. & Aspden, R. M., 14 Jun 2018, In : PloS ONE. 13, 6, 15 p., e0197570.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
9 Downloads (Pure)

Investigation of the Relationship Between Susceptibility Loci for Hip Osteoarthritis and Dual X‐Ray Absorptiometry–Derived Hip Shape in a Population‐Based Cohort of Perimenopausal Women

Baird, D. A., Paternoster, L., Gregory, J. S., Faber, B. G., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Lawlor, D. A., Aspden, R. M. & Tobias, J. H., Dec 2018, In : Arthritis & Rheumatology. 70, 12, p. 1984-1993 10 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
1 Downloads (Pure)

Markers of oxidative stress, skeletal muscle mass and function, and their responses to resistance exercise training in older adults

Carru, C., Da Boit, M., Paliogiannis, P., Zinellu, A., Sotgia, S., Sibson, R., Meakin, J. R., Aspden, R. M., Mangoni, A. A. & Gray, S. R., Mar 2018, In : Experimental Gerontology. 103, p. 101-106 6 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
4 Downloads (Pure)

Mechanical properties of cancellous bone from the acetabulum in relation to acetabular shell fixation and compared with the corresponding femoral head

Van Ladesteijn, R., Leslie, H., Manning, W. A., Holland, J. P., Deeham, D. J., Pandorf, T. & Aspden, R. M., Mar 2018, In : Medical Engineering & Physics. 53, p. 75-81 7 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
7 Downloads (Pure)

Predictors of total hip replacement: Data from the Tasmanian Older Adult Cohort Study

Mezhov, V., Laslett, L., Ahedi, H., Blizzard, L., Aspden, R., Gregory, J., Saunders, F., Graves, S., Lorimer, M., Munugoda, I., Cicuttini, F. & Jones, G., May 2018, In : Internal medicine journal. 48, Suppl. 4, p. 11 1 p.

Research output: Contribution to journalAbstract

Sex differences in the associations between L-arginine pathway metabolites, skeletal muscle mass and function, and their responses to resistance exercise, in old age

Da Boit, M., Tommasi, S., Elliot, D., Zinellu, A., Sotgia, S., Sibson, R., Meakin, J., Aspden, R. M., Carru, C., Mangoni, A. A. & Gray, S. R., 30 Apr 2018, In : Journal of Nutrition, Health & Aging. 22, 4, p. 534-540 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
7 Downloads (Pure)

Significant morphological change in osteoarthritic hips identified over 6–12 months using statistical shape modelling

Barr, R. J., Gregory, J. S., Yoshida, K., Alesci, S., Aspden, R. M. & Reid, D. M., Jun 2018, In : Osteoarthritis and Cartilage. 26, 6, p. 783-789 7 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
5 Downloads (Pure)

Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults

Pavlova, A. V., Meakin, J. R., Cooper, K., Barr, R. J. & Aspden, R. M., 2018, In : BMJ Open Sport & Exercise Medicine. 4, 1, e000374.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
4 Downloads (Pure)
2017

Age-related changes in the effects of strength training on lower leg muscles in healthy individuals measured using MRI

Psatha, M., Wu, Z., Gammie, F., Ratkevicius, A., Wackerhage, H., Redpath, T. W., Gilbert, F. J., Meakin, J. R. & Aspden, R. M., 2017, In : BMJ Open. 3, e000249.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
6 Downloads (Pure)

Associations between BMI across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort

Muthuri, S., Saunders, F. R., Pavlova, A. V., Hardy, R., Kuh, D., Aspden, R. M., Barr, R. J., Gregory, J. S. & Cooper, R., Apr 2017, In : Osteoarthritis and Cartilage. 25, Suppl. 1, p. S86-s87 2 p., 105.

Research output: Contribution to journalAbstract

Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort

Muthuri, S. G., Saunders, F. R., Hardy, R. J., Pavlova, A. V., Martin, K. R., Gregory, J. S., Barr, R. J., Adams, J. E., Kuh, D., Aspden, R. M. & Cooper, R., Dec 2017, In : Bone. 105, p. 115-121 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
10 Downloads (Pure)

Cross-sectional associations between variations in ankle shape by statistical shape modeling, injury history, and race: the Johnston County Osteoarthritis Project

Nelson, A. E., Golightly, Y. M., Lateef, S., Renner, J. B., Jordan, J. M., Aspden, R. M., Hillstrom, H. & Gregory, J. S., 26 Jul 2017, In : Journal of Foot and Ankle Research. 10, 34.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
7 Downloads (Pure)

DXA-derived hip shape is related to osteoarthritis: findings from in the MrOS cohort

Faber, B., Baird, D., Gregson, C., Gregory, J. S., Barr, R. Y., Aspden, R. M., Lynch, J., Nevitt, M., Lane, N. E., Orwoll, E. & Tobias, J., Dec 2017, In : Osteoarthritis and Cartilage. 25, 12, p. 2031-2038 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
4 Downloads (Pure)

Hip Shape as a Predictor of Osteoarthritis Progression in a Prospective Population Cohort

Ahedi, H. G., Aspden, R. M., Blizzard, L. C., Saunders, F. R., Cicuttini, F. M., Aitken, D. A., Jones, G. & Gregory, J. S., Oct 2017, In : Arthritis Care & Research. 69, 10, p. 1566-1573 8 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
5 Downloads (Pure)

MRI and the distribution of bone marrow fat in hip osteoarthritis

Gregory, J. S., Barr, R. J., Varela, V., Ahearn, T. S., Gardiner, J. L., Gilbert, F. J., Redpath, T. W., Hutchison, J. D. & Aspden, R. M., 1 Jan 2017, In : Journal of Magnetic Resonance Imaging. 45, 1, p. 42–50 9 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
7 Downloads (Pure)

Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial

Da Boit, M., Sibson, R., Sivasubramaniam, S., Meakin, J. R., Greig, C. A., Aspden, R., Thies, F., Jeromson, S., Hamilton, D. L., Speakman, J. R., Hambly, C., Mangoni, A. A., Preston, T. & Gray, S. R., Jan 2017, In : The American Journal of Clinical Nutrition. 105, 1, p. 151-158 8 p.

Research output: Contribution to journalArticle

Open Access
File
55 Citations (Scopus)
4 Downloads (Pure)

Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development

Pavlova, A. V., Saunders, F. R., Muthuri, S. G., Gregory, J. S., Barr, R. J., Martin, K. R., Hardy, R. J., Cooper, R., Adams, J. E., Kuh, D. & Aspden, R. M., Aug 2017, In : Journal of Anatomy. 231, 2, p. 248-259 12 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
9 Downloads (Pure)

The roles of NHERF-1 and AKT in osteoarthritis

Griffin-Walker, T. G., McKenna, K. J., Blair, M. C., Samy, D., White, R., Saunders, F. R. & Aspden, R. M., Apr 2017, In : Osteoarthritis and Cartilage. 25, Suppl. 1, p. S153-S153 1 p.

Research output: Contribution to journalAbstract

2016

Can radiographs of hip fractures predict subsequent hip fractures? A shape modeling analysis

Neilly, D., Khan, S. K., Gregory, J. S., Aspden, R. M., Hutchison, J. D. & Deehan, D. J., Jul 2016, In : Injury. 47, 7, p. 1543-1546 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genome-wide association of multiple complex traits in outbred mice by ultra low-coverage sequencing

Nicod, J., Davies, R. W., Cai, N., Hassett, C., Goodstadt, L., Cosgrove, C., Yee, B. K., Lionikaite, V., McIntyre, R. E., Remme, C. A., Lodder, E. M., Gregory, J. S., Hough, T., Joynson, R., Phelps, H., Nell, B., Rowe, C., Wood, J., Walling, A., Bopp, N. & 22 others, Bhomra, A., Hernandez-Pliego, P., Callebert, J., Aspden, R. M., Talbot, N. P., Robbins, P. A., Harrison, M., Fray, M., Launay, J-M., Pinto, Y. M., Blizard, D. A., Bezzina, C. R., Adams, D. J., Franken, P., Weaver, T., Wells, S., Brown, S. D. M., Potter, P. K., Klenerman, P., Lionikas, A., Mott, R. & Flint, J., 31 Aug 2016, In : Nature Genetics. 48, 8, p. 912-918 7 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
5 Downloads (Pure)

Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice

Khalid, A. B., Goodyear, S. R., Ross, R. A. & Aspden, R. M., Oct 2016, In : Medical Engineering & Physics. 38, 10, p. 1044-1054 11 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
5 Downloads (Pure)

Morphology

Aspden, R. & Gregory, J. S., 6 Oct 2016, Oxford Textbook of Osteoarthritis and Crystal Arthropathy. Doherty, M., Hunter, D. J., Bijlsma, H., Arden, N. & Dalbeth, N. (eds.). 3 ed. Oxford University Press, 6 p. 11

Research output: Chapter in Book/Report/Conference proceedingChapter

Sex differences in the response to resistance exercise training in older people

Da Boit, M., Sibson, R., Meakin, J. R., Aspden, R. M., Thies, F., Mangoni, A. & Gray, S. R., Jun 2016, In : Physiological reports. 4, 12, e12834 .

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
6 Downloads (Pure)

Variations in Hip Shape Are Associated with Radiographic Knee Osteoarthritis: Cross-sectional and Longitudinal Analyses of the Johnston County Osteoarthritis Project

Nelson, A. E., Golightly, Y. M., Renner, J. B., Schwartz, T. A., Liu, F., Lynch, J. A., Gregory, J. S., Aspden, R. M., Lane, N. E. & Jordan, J. M., 1 Feb 2016, In : Journal of Rheumatology. 43, 2, p. 405-410 6 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
4 Downloads (Pure)

Variations in hip shape in individuals entering early old age

Saunders, F., Muthuri, S., Pavlova, A. V., Adams, J., Kuh, D., Aspden, R., Barr, R. & Gregory, J. S., Apr 2016, In : Osteoarthritis and Cartilage. 24, Suppl. 1, p. S246 1 p.

Research output: Contribution to journalAbstract

Open Access
7 Citations (Scopus)

Variations in spine shape with body size, BMD and sex in individuals entering early old age

Pavlova, A. V., Muthuri, S., Saunders, F. R., Adams, J., Kuh, D., Aspden, R. M., Gregory, J. S. & Barr, R. J., Apr 2016, In : Osteoarthritis and Cartilage. 24, Suppl. 1, p. S246-S247 2 p.

Research output: Contribution to journalAbstract

Open Access

Viscoelastic properties of human and bovine articular cartilage: a comparison of frequency-dependent trends

Temple, D. K., Cederlund, A. A., Lawless, B. M., Aspden, R. M., Aspden, R. M. & Espino, D. M., 6 Oct 2016, In : BMC Musculoskeletal Disorders. 17, p. 1-8 8 p., 419.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
8 Downloads (Pure)
2015

A longitudinal study of muscle rehabilitation in the lower leg after cast removal using Magnetic Resonance Imaging and strength assessment

Psatha, M., Wu, Z. Q., Gammie, F. M., Ratkevicius, A., Wackerhage, H., Lee, J. H., Redpath, T. W., Gilbert, F. J., Ashcroft, G. P., Meakin, J. R. & Aspden, R. M., 2015, In : International Biomechanics. 2, 1, p. 101-112 12 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)

Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone

Khalid, A. B., Goodyear, S. R., Ross, R. A. & Aspden, R. M., 23 Jan 2015, In : Cogent Engineering. 2, 1, 9 p., 1001015.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)

Polyamines in Osteoarthritis

Saunders, F., Gregory, J., Barr, R. J. & Aspden, R. M., Apr 2015, In : Osteoarthritis and Cartilage. 23, Supplement 2, p. A87-A88 2 p.

Research output: Contribution to journalAbstract

Open Access

Prediction of poor outcome by a novel imaging biomarker (active shape modelling) in hip OA patients

Gregory, J. S., Aspden, R. M., Reid, D. M. & Barr, R. J., Apr 2015, In : Osteoarthritis and Cartilage. 23, Suppl. 2, p. A220-A221 2 p.

Research output: Contribution to journalAbstract

Reproducibility and Diagnostic Accuracy of Kellgren-Lawrence Grading for Osteoarthritis Using Radiographs and Dual-Energy X-ray Absorptiometry Images

Yoshida, K., Barr, R. J., Galea-Soler, S., Aspden, R. M., Reid, D. M. & Gregory, J. S., Apr 2015, In : Journal of Clinical Densitometry. 18, 2, p. 239-244 6 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
35 Downloads (Pure)

The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse

Mitchell, S. E., Tang, Z., Kerbois, C., Delville, C., Konstantopedos, P., Bruel, A., Derous, D., Green, C., Aspden, R. M., Goodyear, S. R., Chen, L., Han, J. J. D., Wang, Y., Promislow, D. E. L., Lusseau, D., Douglas, A. & Speakman, J. R., 6 Jun 2015, In : Oncotarget. 6, 18, p. 15902-15930 29 p.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
9 Downloads (Pure)

The influence of the strength of bone on the deformation of acetabular shells: a laboratory experiment in cadavers

Bone, M. C., Dold, P., Flohr, M., Preuss, R., Joyce, T. J., Aspden, R. M., Holland, J. & Deehan, D., Apr 2015, In : The Journal of Bone and Joint Surgery - British volume . 97-B, 4, p. 473-477 5 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
23 Downloads (Pure)

The role of sodium hydrogen exchanger regulatory factor 1 in osteoarthritis

White, R., Blair, M. C., Saunders, F. & Aspden, R., Apr 2015, In : Osteoarthritis and Cartilage. 23, Supplement 2, p. A134-A135

Research output: Contribution to journalAbstract

Open Access
23 Citations (Scopus)
2014

Foot morphology in osteoarthritis and hallux valgus

Milliken, N., Menz, H. B., Roddy, E., Peat, G., Aspden, R. M., Marshall, M. & Gregory, J. S., Apr 2014, In : Osteoarthritis and Cartilage. 22, Supplement, p. S302 1 p.

Research output: Contribution to journalAbstract