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1994 …2020

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2020

Is intrinsic lumbar spine shape associated with Lumbar Disc Degeneration? An exploratory study

Deane, J. A., Pavlova, A. V., Lim, A. K. P., Gregory, J. S., Aspden, R. M. & McGregor, A. H., 13 Apr 2020, (Accepted/In press) In : BMC Musculoskeletal Disorders.

Research output: Contribution to journalArticle

Motor development in infancy and spine shape in early old age: findings from a British birth cohort study

Saunders, F. R., Gregory, J. S., Pavlova, A., Muthuri, S. G., Hardy, R. J., Martin, K. R., Barr, R. J., Adams, J. E., Kuh, D., Aspden, R. M., Cooper, R. & Ireland, A., 18 Mar 2020, In : Journal of Orthopaedic Research. 9 p.

Research output: Contribution to journalArticle

Open Access

Sex differences in proximal femur shape: findings from a population-based study in adolescents

Frysz, M., Gregory, J., Aspden, R. M., Paternoster, L. & Tobias, J. H., 12 Mar 2020, In : Scientific Reports. 10, 4612.

Research output: Contribution to journalArticle

Open Access
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2 Downloads (Pure)

Statistical shape modelling provides a responsive measure of morphological change in knee osteoarthritis over 12 months

Gregory, J. S., Barr, R. J., Yoshida, K., Alesci, S., Reid, D. M. & Aspden, R. M., 14 Jan 2020, In : Rheumatology.

Research output: Contribution to journalArticle

The effect of pubertal timing, as reflected by height tempo, on proximal femur shape: findings from a population-based study in adolescents

Frysz, M., Gregory, J. S., Aspden, R. M., Paternoster, L. & Tobias, J. H., Feb 2020, In : Bone. 131, 8 p., 115179.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
3 Downloads (Pure)
2019

Age at Onset of Walking in Infancy Is Associated With Hip Shape in Early Old Age

Ireland, A., Saunders, F. R., Muthuri, S. G., Pavlova, A., Hardy, R., Martin, K., Barr, R., Kuh, D., Aspden, R. M., Gregory, J. & Cooper, R., Mar 2019, In : Journal of Bone and Mineral Research. 34, 3, p. 455-463 9 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
10 Downloads (Pure)

Identification of Novel Loci Associated With Hip Shape: A Meta‐Analysis of Genomewide Association Studies

Baird, D. A., Evans, D. S., Kamanu, F. K., Gregory, J. S., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Aspden, R. M., Jenkins, D., Kiel, D. P., Orwoll, E. S., Cummings, S. R., Lane, N. E., Mullin, B. H., Williams, F. MK., Richards, J. B., Wilson, S. G., Spector, T. D., Faber, B. G., Lawlor, D. A. & 10 others, Grundberg, E., Ohlsson, C., Pettersson-Kymmer, U., Capellini, T. D., Richard, D., Beck, T. J., Evans, D. M., Paternoster, L., Karasik, D. & Tobias, J. H., Feb 2019, In : Journal of Bone and Mineral Research. 34, 2, p. 241-251 11 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
5 Downloads (Pure)

Osteoarthritis as an organ disease: from the cradle to the grave

Aspden, R. M. & Saunders, F., 30 Jan 2019, In : European Cells & Materials. 37, p. 74-87 14 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
7 Downloads (Pure)

Perinatal factors associate with vertebral size and shape but not lumbar lordosis in 10-year-old children

Pavlova, A., Jeffrey, J. E., Barr, R. J. & Aspden, R. M., Oct 2019, In : Journal of Anatomy. 235, 4, p. 749-756 8 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
11 Downloads (Pure)
2018

Associations between back pain across adulthood and spine shape in early old age in a British birth cohort

Muthuri, S. G., Pavlova, A., Saunders, F. R., Hardy, R. J., Gregory, J. S., Barr, R. J., Martin, K. R., Adams, J. E., Kuh, D., Aspden, R. M. & Cooper, R., 5 Nov 2018, In : Scientific Reports. 8, 16309.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
7 Downloads (Pure)

Body mass index and waist circumference in early adulthood are associated with thoracolumbar spine shape at age 60-64: the Medical Research Council National Survey of Health and Development

Pavlova, A. V., Muthuri, S. G., Cooper, R., Saunders, F. R., Gregory, J. S., Barr, R., Martin, K. R., Adams, J. E., Kuh, D., Hardy, R. J. & Aspden, R. M., 14 Jun 2018, In : PloS ONE. 13, 6, 15 p., e0197570.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
9 Downloads (Pure)

Investigation of the Relationship Between Susceptibility Loci for Hip Osteoarthritis and Dual X‐Ray Absorptiometry–Derived Hip Shape in a Population‐Based Cohort of Perimenopausal Women

Baird, D. A., Paternoster, L., Gregory, J. S., Faber, B. G., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Lawlor, D. A., Aspden, R. M. & Tobias, J. H., Dec 2018, In : Arthritis & Rheumatology. 70, 12, p. 1984-1993 10 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
1 Downloads (Pure)

Markers of oxidative stress, skeletal muscle mass and function, and their responses to resistance exercise training in older adults

Carru, C., Da Boit, M., Paliogiannis, P., Zinellu, A., Sotgia, S., Sibson, R., Meakin, J. R., Aspden, R. M., Mangoni, A. A. & Gray, S. R., Mar 2018, In : Experimental Gerontology. 103, p. 101-106 6 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
4 Downloads (Pure)

Mechanical properties of cancellous bone from the acetabulum in relation to acetabular shell fixation and compared with the corresponding femoral head

Van Ladesteijn, R., Leslie, H., Manning, W. A., Holland, J. P., Deeham, D. J., Pandorf, T. & Aspden, R. M., Mar 2018, In : Medical Engineering & Physics. 53, p. 75-81 7 p.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
7 Downloads (Pure)

Sex differences in the associations between L-arginine pathway metabolites, skeletal muscle mass and function, and their responses to resistance exercise, in old age

Da Boit, M., Tommasi, S., Elliot, D., Zinellu, A., Sotgia, S., Sibson, R., Meakin, J., Aspden, R. M., Carru, C., Mangoni, A. A. & Gray, S. R., 30 Apr 2018, In : Journal of Nutrition, Health & Aging. 22, 4, p. 534-540 7 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
7 Downloads (Pure)

Significant morphological change in osteoarthritic hips identified over 6–12 months using statistical shape modelling

Barr, R. J., Gregory, J. S., Yoshida, K., Alesci, S., Aspden, R. M. & Reid, D. M., Jun 2018, In : Osteoarthritis and Cartilage. 26, 6, p. 783-789 7 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
5 Downloads (Pure)

Variation in lifting kinematics related to individual intrinsic lumbar curvature: an investigation in healthy adults

Pavlova, A. V., Meakin, J. R., Cooper, K., Barr, R. J. & Aspden, R. M., 2018, In : BMJ Open Sport & Exercise Medicine. 4, 1, e000374.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
4 Downloads (Pure)
2017

Age-related changes in the effects of strength training on lower leg muscles in healthy individuals measured using MRI

Psatha, M., Wu, Z., Gammie, F., Ratkevicius, A., Wackerhage, H., Redpath, T. W., Gilbert, F. J., Meakin, J. R. & Aspden, R. M., 2017, In : BMJ Open. 3, e000249.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
6 Downloads (Pure)

Associations between body mass index across adult life and hip shapes at age 60 to 64: Evidence from the 1946 British birth cohort

Muthuri, S. G., Saunders, F. R., Hardy, R. J., Pavlova, A. V., Martin, K. R., Gregory, J. S., Barr, R. J., Adams, J. E., Kuh, D., Aspden, R. M. & Cooper, R., Dec 2017, In : Bone. 105, p. 115-121 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
10 Downloads (Pure)

Cross-sectional associations between variations in ankle shape by statistical shape modeling, injury history, and race: the Johnston County Osteoarthritis Project

Nelson, A. E., Golightly, Y. M., Lateef, S., Renner, J. B., Jordan, J. M., Aspden, R. M., Hillstrom, H. & Gregory, J. S., 26 Jul 2017, In : Journal of Foot and Ankle Research. 10, 34.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
7 Downloads (Pure)

DXA-derived hip shape is related to osteoarthritis: findings from in the MrOS cohort

Faber, B., Baird, D., Gregson, C., Gregory, J. S., Barr, R. Y., Aspden, R. M., Lynch, J., Nevitt, M., Lane, N. E., Orwoll, E. & Tobias, J., Dec 2017, In : Osteoarthritis and Cartilage. 25, 12, p. 2031-2038 8 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
4 Downloads (Pure)

Hip Shape as a Predictor of Osteoarthritis Progression in a Prospective Population Cohort

Ahedi, H. G., Aspden, R. M., Blizzard, L. C., Saunders, F. R., Cicuttini, F. M., Aitken, D. A., Jones, G. & Gregory, J. S., Oct 2017, In : Arthritis Care & Research. 69, 10, p. 1566-1573 8 p.

Research output: Contribution to journalArticle

Open Access
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15 Citations (Scopus)
5 Downloads (Pure)

MRI and the distribution of bone marrow fat in hip osteoarthritis

Gregory, J. S., Barr, R. J., Varela, V., Ahearn, T. S., Gardiner, J. L., Gilbert, F. J., Redpath, T. W., Hutchison, J. D. & Aspden, R. M., 1 Jan 2017, In : Journal of Magnetic Resonance Imaging. 45, 1, p. 42–50 9 p.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
7 Downloads (Pure)

Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial

Da Boit, M., Sibson, R., Sivasubramaniam, S., Meakin, J. R., Greig, C. A., Aspden, R., Thies, F., Jeromson, S., Hamilton, D. L., Speakman, J. R., Hambly, C., Mangoni, A. A., Preston, T. & Gray, S. R., Jan 2017, In : The American Journal of Clinical Nutrition. 105, 1, p. 151-158 8 p.

Research output: Contribution to journalArticle

Open Access
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53 Citations (Scopus)
4 Downloads (Pure)

Statistical shape modelling of hip and lumbar spine morphology and their relationship in the MRC National Survey of Health and Development

Pavlova, A. V., Saunders, F. R., Muthuri, S. G., Gregory, J. S., Barr, R. J., Martin, K. R., Hardy, R. J., Cooper, R., Adams, J. E., Kuh, D. & Aspden, R. M., Aug 2017, In : Journal of Anatomy. 231, 2, p. 248-259 12 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
9 Downloads (Pure)
2016

Can radiographs of hip fractures predict subsequent hip fractures? A shape modeling analysis

Neilly, D., Khan, S. K., Gregory, J. S., Aspden, R. M., Hutchison, J. D. & Deehan, D. J., Jul 2016, In : Injury. 47, 7, p. 1543-1546 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Genome-wide association of multiple complex traits in outbred mice by ultra low-coverage sequencing

Nicod, J., Davies, R. W., Cai, N., Hassett, C., Goodstadt, L., Cosgrove, C., Yee, B. K., Lionikaite, V., McIntyre, R. E., Remme, C. A., Lodder, E. M., Gregory, J. S., Hough, T., Joynson, R., Phelps, H., Nell, B., Rowe, C., Wood, J., Walling, A., Bopp, N. & 22 others, Bhomra, A., Hernandez-Pliego, P., Callebert, J., Aspden, R. M., Talbot, N. P., Robbins, P. A., Harrison, M., Fray, M., Launay, J-M., Pinto, Y. M., Blizard, D. A., Bezzina, C. R., Adams, D. J., Franken, P., Weaver, T., Wells, S., Brown, S. D. M., Potter, P. K., Klenerman, P., Lionikas, A., Mott, R. & Flint, J., 31 Aug 2016, In : Nature Genetics. 48, 8, p. 912-918 7 p.

Research output: Contribution to journalArticle

Open Access
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46 Citations (Scopus)
5 Downloads (Pure)

Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice

Khalid, A. B., Goodyear, S. R., Ross, R. A. & Aspden, R. M., Oct 2016, In : Medical Engineering & Physics. 38, 10, p. 1044-1054 11 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
5 Downloads (Pure)

Sex differences in the response to resistance exercise training in older people

Da Boit, M., Sibson, R., Meakin, J. R., Aspden, R. M., Thies, F., Mangoni, A. & Gray, S. R., Jun 2016, In : Physiological reports. 4, 12, e12834 .

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
6 Downloads (Pure)

Variations in Hip Shape Are Associated with Radiographic Knee Osteoarthritis: Cross-sectional and Longitudinal Analyses of the Johnston County Osteoarthritis Project

Nelson, A. E., Golightly, Y. M., Renner, J. B., Schwartz, T. A., Liu, F., Lynch, J. A., Gregory, J. S., Aspden, R. M., Lane, N. E. & Jordan, J. M., 1 Feb 2016, In : Journal of Rheumatology. 43, 2, p. 405-410 6 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
4 Downloads (Pure)

Viscoelastic properties of human and bovine articular cartilage: a comparison of frequency-dependent trends

Temple, D. K., Cederlund, A. A., Lawless, B. M., Aspden, R. M., Aspden, R. M. & Espino, D. M., 6 Oct 2016, In : BMC Musculoskeletal Disorders. 17, p. 1-8 8 p., 419.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
8 Downloads (Pure)
2015

A longitudinal study of muscle rehabilitation in the lower leg after cast removal using Magnetic Resonance Imaging and strength assessment

Psatha, M., Wu, Z. Q., Gammie, F. M., Ratkevicius, A., Wackerhage, H., Lee, J. H., Redpath, T. W., Gilbert, F. J., Ashcroft, G. P., Meakin, J. R. & Aspden, R. M., 2015, In : International Biomechanics. 2, 1, p. 101-112 12 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)

Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone

Khalid, A. B., Goodyear, S. R., Ross, R. A. & Aspden, R. M., 23 Jan 2015, In : Cogent Engineering. 2, 1, 9 p., 1001015.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)

Reproducibility and Diagnostic Accuracy of Kellgren-Lawrence Grading for Osteoarthritis Using Radiographs and Dual-Energy X-ray Absorptiometry Images

Yoshida, K., Barr, R. J., Galea-Soler, S., Aspden, R. M., Reid, D. M. & Gregory, J. S., Apr 2015, In : Journal of Clinical Densitometry. 18, 2, p. 239-244 6 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
35 Downloads (Pure)

The effects of graded levels of calorie restriction: I. impact of short term calorie and protein restriction on body composition in the C57BL/6 mouse

Mitchell, S. E., Tang, Z., Kerbois, C., Delville, C., Konstantopedos, P., Bruel, A., Derous, D., Green, C., Aspden, R. M., Goodyear, S. R., Chen, L., Han, J. J. D., Wang, Y., Promislow, D. E. L., Lusseau, D., Douglas, A. & Speakman, J. R., 6 Jun 2015, In : Oncotarget. 6, 18, p. 15902-15930 29 p.

Research output: Contribution to journalArticle

Open Access
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32 Citations (Scopus)
9 Downloads (Pure)

The influence of the strength of bone on the deformation of acetabular shells: a laboratory experiment in cadavers

Bone, M. C., Dold, P., Flohr, M., Preuss, R., Joyce, T. J., Aspden, R. M., Holland, J. & Deehan, D., Apr 2015, In : The Journal of Bone and Joint Surgery - British volume . 97-B, 4, p. 473-477 5 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
23 Downloads (Pure)
2014

How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study

Merle, C., Waldstein, W., Gregory, J. S., Goodyear, S. R., Aspden, R. M., Aldinger, P. R., Murray, D. W. & Gill, H. S., Mar 2014, In : Journal of Orthopaedic Research. 32, 3, p. 413-422 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension

Pavlova, A. V., Meakin, J. R., Cooper, K., Barr, R. J. & Aspden, R. M., Apr 2014, In : European Spine Journal. 23, 1 Suppl. , p. 26-32 7 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
6 Downloads (Pure)

The mechanical and material properties of elderly human articular cartilage subject to impact and slow loading

Burgin, L. V., Edelsten, L. & Aspden, R. M., Feb 2014, In : Medical Engineering & Physics. 36, 2, p. 226-232 7 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
4 Downloads (Pure)
Open Access
File
6 Citations (Scopus)
32 Downloads (Pure)
2013

Can we improve the prediction of hip fracture by assessing bone structure using shape and appearance modelling?

Goodyear, S. R., Barr, R. J., McCloskey, E., Alesci, S., Aspden, R. M., Reid, D. M. & Gregory, J. S., 1 Mar 2013, In : Bone. 53, 1, p. 188-193 6 p.

Research output: Contribution to journalArticle

File
29 Citations (Scopus)
1 Downloads (Pure)

Endothelial nitric oxide synthase is not essential for nitric oxide production by osteoblasts subjected to fluid shear stress in vitro

Bakker, A. D., Huesa, C., Hughes, A., Aspden, R. M., van't Hof, R. J., Klein-Nulend, J. & Helfrich, M., Mar 2013, In : Calcified Tissue International. 92, 3, p. 228-239 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Proximal femoral canal shape is more accurately assessed on AP hip radiographs than AP pelvis radiographs in primary hip osteoarthritis

Merle, C., Waldstein, W., Gregory, J. S., Goodyear, S. R., Aspden, R. M., Aldinger, P. R., Murray, D. W. & Gill, H. S., 2013, In : Hip International. 23, 5, p. 484-491 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2012

A longitudinal MRI study of muscle atrophy during lower leg immobilization following ankle fracture

Psatha, M., Wu, Z., Gammie, F. M., Ratkevicius, A., Wackerhage, H., Lee, J. H., Redpath, T. W., Gilbert, F. J., Ashcroft, G. P., Meakin, J. R. & Aspden, R. M., Mar 2012, In : Journal of Magnetic Resonance Imaging. 35, 3, p. 686-695 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
8 Citations (Scopus)
2 Downloads (Pure)

Predicting OA progression to total hip replacement: can we do better than risk factors alone using active shape modelling as an imaging biomarker?

Barr, R. J., Gregory, J. S., Reid, D. M., Aspden, R. M., Yoshida, K., Hosie, G., Silman, A. J., Alesci, S. & Macfarlane, G. J., 1 Mar 2012, In : Rheumatology. 51, 3, p. 562-570 9 p.

Research output: Contribution to journalArticle

Open Access
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35 Citations (Scopus)
6 Downloads (Pure)