Roger Pertwee

Professor

    • 26223 Citations
    1970 …2020
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    Research Output 1970 2020

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    2017
    3 Citations (Scopus)

    The pharmacology and therapeutic potential of plant cannabinoids

    Cascio, M. G., Pertwee, R. G. & Marini, P., 2017, Cannabis sativa L. - Botany and Biotechnology. Chandra, S., Lata, H. & ElSohly, M. A. (eds.). Springer, Biomedicine & Life Sciences, p. 207-225 19 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Cannabinoids
    Pharmacology
    Dronabinol
    Therapeutics
    Cannabinoid Receptors
    2016
    3 Citations (Scopus)

    The Cyclic AMP Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells

    Marini, P., Cascio, M. G. & Pertwee, R. G., 2016, Endocannabinoid Signaling: Methods and Protocols. Maccarrone, M. (ed.). New York: Springer Science+Business Media, p. 85-93 9 p. (Methods in Molecular Biology; vol. 1412).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Cannabinoid Receptor CB2
    Cyclic AMP
    G-Protein-Coupled Receptors
    Cricetulus
    Pharmacology

    The Displacement Binding Assay Using Human Cannabinoid CB2 Receptor-Transfected Cells

    Cascio, M. G., Marini, P. & Pertwee, R. G., 1 Jun 2016, Endocannabinoid Signaling: Methods and Protocols. Maccarrone, M. (ed.). Springer Science+Business Media, Vol. 1412. p. 57-63 7 p. (Methods in Molecular Biology; vol. 1412).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Cannabinoid Receptor CB2
    Phytochemicals
    Cricetulus
    2009

    Therapeutic applications for agents that act at CB1 and CB2 receptors

    Pertwee, R. G. & Thomas, A., 27 Feb 2009, The Cannabinoid Receptors. Reggio, P. H. (ed.). New York, NY, USA: Humana Press, p. 361-392

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2008
    2 Citations (Scopus)

    CB1 and CB2 receptor pharmacology

    Pertwee, R. G., 21 Apr 2008, Cannabinoids and the Brain. Köfalvi, A. (ed.). New York, NY, USA: Springer Science+Business Media, p. 91-99

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2005

    Cannabidiol as a potential medicine

    Pertwee, R. G., 7 Sep 2005, Cannabinoids as Therapeutics. Mechoulam, R. (ed.). Basel, Switzerland: Birkhaüser Verlag, p. 47-65 (Milestones in Drug Therapy).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    20 Citations (Scopus)

    Cannabinoid receptors and their ligands

    Pertwee, R. G., 21 Mar 2005, Cannabinoids. Pertwee, R. G. (ed.). Heidelberg, Germany: Springer-Verlag, Vol. 168. p. 1-51 (Handbook of Experimental Pharmacology; vol. 168).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The bioassay of cannabinoids using the mouse isolated vas deferens

    Thomas, A. & Pertwee, R. G., 15 Nov 2005, Marijuana and Medical Research : Methods and Protocols. Onaivi, E. S. (ed.). Totowa, NJ, USA: Humana Press, p. 191-207 (Methods in Molecular Medicine).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2004

    Angriffspunkte und Wirkungsmechanismen

    Pertwee, R. G., 20 Dec 2004, Cannabis und Cannabinoide: Pharmakologie Toxicologie und therapeutisches Potential. Grotenhermen, F. (ed.). Bern, Switzerland: Verlag Hans Huber, p. 95-113

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Receptors and pharmacodynamics: natural and synthetic cannabinoids and endocannabinoids

    Pertwee, R. G., Jul 2004, The Medicinal Uses of Cannabis and Cannabinoids. Guy, G., Whittle, B. A. & Robson, P. J. (eds.). London, United Kingdom: Pharmaceutical Press, p. 103-139

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The pharmacology and therapeutic potential of cannabidiol

    Pertwee, R. G., 20 Jul 2004, Cannabinoids. Di Marzo, V. (ed.). New York, NY, USA: . Kluwer Academic/Plenum Publishers, p. 32-83 (Neuroscience Intelligence Unit).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2003

    Cannabinoids

    Pertwee, R. G., 13 May 2003, Pain: Current Understanding, Emerging Therapies, and Novel Approaches to Drug Discovery. Munglani, R., Schmidt, W. K. & Bountra, C. (eds.). New York, NY, USA: Marcel Dekker, p. 683-706 (Pain Management).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    11 Citations (Scopus)

    Inverse agonism at cannabinoid receptors

    Pertwee, R. G., 17 Sep 2003, Inverse Agonism: Proceedings of the Esteve Foundation Symposium X, S'Agaró (Girona), Spain, 2-5 October 2002. Ijzerman, A. P. (ed.). Amsterdam, Netherlands: Elsevier, Vol. 10. p. 75-86 (International Congress Series; no. 1249).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Lugares y mecanismos de acción

    Pertwee, R. G., 2003, Cannabis y Cannabinoides: Farmacología, toxicología y potencial terapéutico. Varo, R. N., Russo, E. & Grotenhermen, F. (eds.). New York, NY, USA: Haworth Press, p. 95-113

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2002

    New developments in the pharmacology of cannabinoids

    Pertwee, R. G., 8 Feb 2002, Trends in Drug Research III: Proceedings of the 13th Noordwijkerhout-Camerino Symposium. van der Goot, H. (ed.). Amsterdam, Netherlands: Elsevier Science , Vol. 32. p. 249-258 (Pharmacochemistry Library; vol. 32).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Sites and Mechanisms of Action

    Pertwee, R. G., 15 May 2002, Cannabis and Cannabinoids: Pharmacology Toxicology and Therapeutic Potential. Grotenhermen, F. & Russo, E. (eds.). New York, NY, USA: Haworth Press, p. 73-87 15 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2001

    Angriffspunkte und Wirkungsmechanismen: Targets and mechanisms of action

    Pertwee, R. G., 1 Jan 2001, Cannabis und Cannabinoide: Pharmakologie Toxicologie und therapeutisches Potential. Grotenhermen, F. (ed.). Bern: Huber-Verlag, p. 93-107

    Research output: Chapter in Book/Report/Conference proceedingChapter

    2000

    Cannabinoids and pain modulation in animals and humans.

    Holdcroft, A., Hargreaves, K. M., Rice, A. S. C. & Pertwee, R. G., 2000, Proceedings of the 9th World Congress on Pain, . Devor, M., Rowbotham, M. C. & Wiesenfeld-Hallin, Z. (eds.). Seattle: IASP Press, Vol. 16. p. 915-926 (Progress in Pain Research and Management).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1999

    Cannabinoid receptors and their ligands in brain and other tissues

    Pertwee, R. G., 5 Apr 1999, Marihuana and Medicine. Nahas, G. G., Sutin, K. M., Harvey, D. J. & Agurell, S. (eds.). Totowa, NJ, USA: Humana Press, p. 177-185

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1998

    Advances in cannabinoid receptor pharmacology

    Pertwee, R. G., 19 Nov 1998, Cannabis. The Genus Cannabis. Brown, D. T. (ed.). Amsterdam, Netherlands: Harwood Academic Publishers, p. 133-185 (Medicinal and Aromatic Plants: Industrial Profiles).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Cannabinoid Receptors

    Howlett, A. C., Bonner, T. I., Cabral, G., Casellas, P., Devane, W. A., Felder, C. C., Herkenham, M., Martin, B. R., Mechoulam, R. & Pertwee, R. G., 1998, The IUPHAR Compendium of Receptor Characterization and Classification: International Union of Pharmacology Committee on Receptor Characterization and Classification. Girdlestone, D. (ed.). London, United Kingdom: IUPHAR Media, p. 97-104

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Characterization of Cannabinoid Receptors in the Spleen and in Mast Cells

    Ross, R. A., Murphy, V. L., McKay, N. G., Ashford, M. L. J. & Pertwee, R. G., Dec 1998, Essential Fatty Acids and Eicosanoids: Proceedings of the 4th Int. Congress on Fatty Acids and Eicosanoids, Edinburgh. Riemersma, R., Armstrong, R., Kelly, R. & Wilson, R. (eds.). Champaign: AOCS Press, p. 376-379

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1995

    Pharmacological, physiological and clinical implications of the discovery of cannabinoid receptors: an overview

    Pertwee, R. G., Mar 1995, Cannabinoid Receptors. Pertwee, R. G. (ed.). London, United Kingdom: Academic Press, p. 1-34 (Neuroscience Perspectives).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1994

    Cannabinoid receptors: pharmacology, second messenger systems and endogenous ligands

    Martin, B. R., Childers, S., Howlett, A., Mechoulam, R. & Pertwee, R. G., 1994, Problems of Drug Dependence, 1993: Proceeding of the 55th Annual Scientific Meeting of the College on Problems of Drug Dependence, Inc.. Harris, L. (ed.). Bethesda, MD, USA: National Institutes of Health (NIH), Vol. 1. p. 55-60 (National Institute on Drug Abuse Research Monograph Series; no. 140).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Effect of pretreatment with delta-9-tetrahydrocannabinol on the ability of certain cannabimimetic agents to induce hypothermia in mice

    Pertwee, R. G. & Stevenson, L. A., 1 Feb 1994, Temperature Regulation: Recent Physiological and Pharmacological Advances. Milton, A. S. (ed.). Basel, Switzerland: Birkhäuser, p. 177-182 (Advances in Pharmacological Sciences).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1992

    In vivo interactions between psychotropic cannabinoids and other drugs involving central and peripheral neurochemical mediators

    Pertwee, R. G., 14 Aug 1992, Marijuana/Cannabinoids: Neurobiology and Neurophysiology. Murphy, L. L. & Bartke, A. (eds.). Boca Raton, FL, USA: CRC Press, p. 165-218 (Physiology of Substance Abuse).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Tolerance to and dependence on psychotropic cannabinoids

    Pertwee, R. G., Jan 1992, The Biological Bases of Drug Tolerance and Dependence. Pratt, J. A. (ed.). London, United Kingdom: Academic Press, p. 231-263 (Neuroscience perspectives).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1990

    Hydrostatic pressure modifies behavioural thermoregulation in mice

    MacDonald, A. G., Pertwee, R. G. & Marshall, N. R., 1990, High Pressure Neurological Syndrome - 20 years Later: 1st Meeting of the International Group on High Pressure Biology. Rostain, J-C., Martinez, E. & Lemair, C. (eds.). Marseille, France: ARAS-SNHP, p. 261-273

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The central neuropharmacology of psychotropic cannabinoids

    Pertwee, R. G., 1 Apr 1990, International Encyclopedia of Pharmacology and Therapeutics, Section 130: Psychotropic Drugs of Abuse. Balfour, D. J. K. (ed.). New York, USA: Pergamon Press, p. 355-429

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1989

    Does chlorpromazine enhance the hypothermic response to delta-9-tetrahydrocannabinol by blocking peripheral alpha-adrenoceptors?

    Pertwee, R. G. & Gentleman, S. M., 1989, Thermoregulation: Research and Clinical Applications. Lomax, P. & Schönbaum, E. (eds.). Basel, Switzerland: Karger, p. 197-199

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1988

    Synergistic interactions between delta-9-THC and flurazepam : further studies

    Pertwee, R. G. & Greentree, S. G., 1988, Marijuana: An International Research Report. Chesher, G., Consroe, P. & Musty, R. (eds.). Canberra, Australia: Australian Government Publishing Service, p. 365-370 (Monograph series (National Campaign Against Drug Abuse (Australia)); no. 7).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1986

    An interaction between chlorpromazine and delta-9-tetrahydrocannabinol

    Hedley, D. & Pertwee, R. G., 1986, Homeostasis and Thermal Stress: experimental and therapeutic advances : 6th International symposium on the pharmacology of thermoregulation : Papers . Cooper, K., Lomax, P., Schönbaum, E. & Veale, W. L. (eds.). Basel, Switzerland: Karger, p. 163-165

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The effect of subanaesthetic partial pressures of nitrous oxide and nitrogen on behavioural thermoregulation in mice

    Pertwee, R. G., Marshall, N. R. & MacDonald, A. G., 1986, Homeostasis and Thermal Stress: experimental and therapeutic advances: 6th International symposium on the pharmacology of thermoregulation : Papers . Cooper, K., Lomax, P., Schönbaum, E. & Veale, W. L. (eds.). Basel, Switzerland: Karger, p. 19-21

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1985

    Effects of cannabinoids on thermoregulation: a brief review

    Pertwee, R. G., 1985, Marihuana '84: proceedings of the Oxford Symposium on Cannabis . Harvey, D. J., Paton, S. W. & Nahas, G. G. (eds.). Oxford, United Kingdom: IRL Press, p. 263-277

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1983

    Cannabis

    Pertwee, R. G., 1983, Psychopharmacology 1: Part 1 Preclinical Psychopharmacology. Grahame-Smith, D. G. & Cowen, P. J. (eds.). Amsterdam: Excerpta Medica, Vol. 1. p. 377-397

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Cannabis

    Pertwee, R. G., 1983, Psychopharmacology 2: Part 1 Preclinical Psychopharmacology. Grahame-Smith, D. G. & Cowen, P. J. (eds.). Amsterdam: Elsevier, p. 364-391

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Prostaglandin hyperthermia in mice: effects of ambient temperature

    Milton, A. S., Pertwee, R. G. & Todd, D. A., 1983, Environment, Drugs and Thermoregulation: 5th International Symposium on the Pharmacology of Thermoregulation. Lomax, P. & Schönbaum, E. (eds.). Basel, Switzerland: Karger, p. 150-152

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The effects of intrahypothalamic injections of delta-9-tetrahydrocannabinol, dopamine and prostaglandin E2 on behavioural thermoregulation in mice

    Pertwee, R. G., Moochhala, S., Nyemitei-Addo, I. & Todd, D. A., 1983, Environment, Drugs and Thermoregulation: 5th International Symposium on the Pharmacology of Thermoregulation. Lomax, P. & Schonbaum, E. (eds.). Basel, Switzerland: Karger, p. 82-85

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1982

    Therapeutic agents affecting body temperature

    Pertwee, R. G., 22 Nov 1982, Pyretics and Antipyretics: Handbook of experimental pharmacology ; vol 60 . Milton, A. S. & van Arman, C. G. (eds.). Berlin, Germany: Springer-Verlag, Vol. 60. p. 377-435 (Handbook of Experimental Pharmacology).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1980

    Effects of delta-9-tetrahydrocannabinol on autonomic and behavioural thermoregulation in mice

    Pertwee, R. G. & Tavendale, R., 1980, Thermoregulatory Mechanisms and their Therapeutic Implications: 4th Symposium on the Pharmacology of Thermoregulation. Cox, B., Lomax, P., Milton, A. S. & Schönbaum, E. (eds.). Basel, Switzerland: Karger, p. 57-61

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1973

    Clinical aspects of cannabis action

    Paton, W. D. M., Pertwee, R. G. & Tylden, E., 1973, Marijuana: Chemistry, Pharmacology, Metabolism and Clinical Effects. New York, USA: Academic Press, p. 335-365

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The actions of cannabis in man

    Paton, W. D. M. & Pertwee, R. G., 1973, Marijuana: Chemistry, Pharmacology, Metabolism and Clinical Effects. Mechoulam, R. (ed.). New York,USA: Academic Press, p. 287-333

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The pharmacology of cannabis in animals

    Paton, W. D. M. & Pertwee, R. G., 1973, Marijuana: Chemistry, Pharmacology, Metabolism and Clinical Effects. Mechoulam, R. (ed.). New York, USA: Academic Press, p. 191-285

    Research output: Chapter in Book/Report/Conference proceedingChapter

    1972

    The effect of cannabidiol on the level of delta-1-THC and its metabolites in mouse brain

    Pertwee, R. G., 1972, Cannabis and its derivatives: Pharmacology and Experimental Psychology. Paton, W. D. M. & Crown, J. (eds.). London, United Kingdom: Oxford University Press, p. 193-195 3 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    The general pharmacology of cannabinoids

    Paton, W. D. M., Pertwee, R. G. & Temple, D., 1972, Cannabis and its derivatives: Pharmacology and Experimental Psychology. Paton, W. D. M. & Crown, J. (eds.). London, United Kingdom: Oxford University Press, p. 50-75

    Research output: Chapter in Book/Report/Conference proceedingChapter