Roger Pertwee

Professor

    • 26223 Citations
    1970 …2020
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    Research Output 1970 2020

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    Article
    2020
    1 Downloads (Pure)
    Open Access
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    Cannabinoids
    Pharmacogenetics
    Genes
    Conserved Sequence
    Nucleic Acid Regulatory Sequences
    2019

    Anticancer effects of n-3 EPA and DHA and their endocannabinoid derivatives on breast cancer cell growth and invasion

    Brown, I., Lee, J., Sneddon, A. A., Cascio, M. G., Pertwee, R. G., Wahle, K. W. J., Rotondo, D. & Heys, S. D., 16 Oct 2019, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 102024.

    Research output: Contribution to journalArticle

    Endocannabinoids
    Ethanolamine
    Cell growth
    Breast Neoplasms
    Derivatives
    2 Citations (Scopus)
    2 Downloads (Pure)
    Open Access
    File
    Addictive Behavior
    Cannabinoid Receptors
    Cannabinoids
    Clustered Regularly Interspaced Short Palindromic Repeats
    Anxiety

    Fatty acid suppression of glial activation prevents central neuropathic pain after spinal cord injury

    Georgieva, M., Wei, Y., Dumitrascuta, M., Pertwee, R., Finnerup, N. B. & Huang, W., Dec 2019, In : Pain. 160, 12, p. 2724-2742 19 p.

    Research output: Contribution to journalArticle

    Neuralgia
    Spinal Cord Injuries
    Neuroglia
    Docosahexaenoic Acids
    Fatty Acids
    8 Citations (Scopus)

    Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief

    Gado, F., Di Cesare Mannelli, L., Lucarini, E., Bertini, S., Cappelli, E., Digiacomo, M., Stevenson, L. A., Macchia, M., Tuccinardi, T., Ghelardini, C., Pertwee, R. G. & Manera, C., 10 Jan 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 276-287 12 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptor CB2
    Cannabinoid Receptors
    Neuralgia
    Allosteric Site
    Ligands
    2018
    23 Citations (Scopus)

    Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence

    Slivicki, R. A., Xu, Z., Kulkarni, P. M., Pertwee, R. G., Mackie, K., Thakur, G. A. & Hohmann, A. G., 15 Nov 2018, In : Biological Psychiatry. 84, 10, p. 722-733 12 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptor CB1
    Cannabinoid Receptors
    Monoacylglycerol Lipases
    Paclitaxel
    Cannabinoid Receptor Agonists
    2017
    3 Citations (Scopus)
    7 Downloads (Pure)

    Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers

    Zanato, C., Pelagalli, A., Marwick, K. F. M., Piras, M., Dall'Angelo, S., Spinaci, A., Pertwee, R. G., Wyllie, D. J. A., Hardingham, G. E. & Zanda, M., 2017, In : Organic & Biomolecular Chemistry. 15, 9, p. 2086-2096 11 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Radio
    tracers
    Derivatives
    aspartates
    evaluation
    2016
    21 Citations (Scopus)

    Mapping Cannabinoid 1 Receptor Allosteric Site(s): Critical Molecular Determinant and Signaling Profile of GAT100, a Novel, Potent, and Irreversibly Binding Probe

    Laprairie, R. B., Kulkarni, A. R., Kulkarni, P. M., Hurst, D. P., Lynch, D., Reggio, P. H., Janero, D. R., Pertwee, R. G., Stevenson, L. A., Kelly, M. E. M., Denovan-Wright, E. M. & Thakur, G. A., 15 Jun 2016, In : ACS Chemical Neuroscience. 7, 6, p. 776-798 23 p.

    Research output: Contribution to journalArticle

    33 Citations (Scopus)
    5 Downloads (Pure)

    Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s)

    Kulkarni, P. M., Kulkarni, A. R., Korde, A., Tichkule, R. B., Laprairie, R. B., Denovan-Wright, E. M., Zhou, H., Janero, D. R., Zvonok, N., Makriyannis, A., Cascio, M. G., Pertwee, R. G. & Thakur, G. A., 14 Jan 2016, In : Journal of Medicinal Chemistry. 59, 1, p. 44-60 17 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    2015
    24 Citations (Scopus)

    CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency

    Smoum, R., Baraghithy, S., Chourasia, M., Breuer, A., Mussai, N., Attar-Namdar, M., Kogan, N. M., Raphael, B., Bolognini, D., Cascio, M. G., Marini, P., Pertwee, R. G., Shurki, A., Mechoulam, R. & Bab, I., 14 Jul 2015, In : PNAS. 112, 28, p. 8774-8779 6 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptor Agonists
    Cannabinoid Receptor CB2
    Cannabinoid Receptor CB1
    HU 308
    Ligands
    23 Citations (Scopus)
    4 Downloads (Pure)

    Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease

    Mounsey, R. B., Mustafa, S., Robinson, L., Ross, R. A., Riedel, G., Pertwee, R. G. & Teismann, P., Nov 2015, In : Experimental Neurology. 273, p. 36-44 9 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    10 Citations (Scopus)

    Modulation of food consumption and sleep-wake cycle in mice by the neutral CB1 antagonist ABD459

    Goonawardena, A. V., Plano, A., Robinson, L., Ross, R., Greig, I., Pertwee, R. G., Hampson, R. E., Platt, B. & Riedel, G., Apr 2015, In : Behavioural Pharmacology. 26, 3, p. 289-303 15 p.

    Research output: Contribution to journalArticle

    Sleep
    Food
    Endocannabinoids
    REM Sleep
    Arousal
    11 Citations (Scopus)
    4 Downloads (Pure)

    The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects

    Cascio, M. G., Zamberletti, E., Marini, P., Parolaro, D. & Pertwee, R. G., Mar 2015, In : British Journal of Pharmacology. 172, 5, p. 1305-1318 14 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Serotonin 5-HT1 Receptors
    Receptor, Serotonin, 5-HT1A
    8-Hydroxy-2-(di-n-propylamino)tetralin
    Antipsychotic Agents
    Membranes
    7 Citations (Scopus)
    15 Downloads (Pure)

    Tricyclic fused pyrazoles with a 'Click' 1,2,3-triazole substituent in position 3 are nanomolar CB1 receptor ligands

    Zanato, C., Cascio, M. G., Lazzari, P., Pertwee, R., Testa, A. & Zanda, M., Mar 2015, In : Synthesis. 47, 6, p. 817-826 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Pyrazoles
    Cannabinoid Receptor CB1
    rimonabant
    Triazoles
    Chlorine
    2014
    113 Citations (Scopus)

    Early phytocannabinoid chemistry to endocannabinoids and beyond

    Mechoulam, R., Hanus, L. O., Pertwee, R. & Howlett, A. C., Nov 2014, In : Nature reviews neuroscience. 15, 11, p. 757-764 8 p.

    Research output: Contribution to journalArticle

    45 Citations (Scopus)
    42 Citations (Scopus)

    Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol

    Romano, B., Borrelli, F., Pagano, E., Cascio, M. G., Pertwee, R. G. & Izzo, A. A., 15 Apr 2014, In : Phytomedicine. 21, 5, p. 631-639 9 p.

    Research output: Contribution to journalArticle

    39 Citations (Scopus)

    In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569

    Gamage, T. F., Ignatowska-Jankowska, B. M., Wiley, J. L., Abdelrahman, M., Trembleau, L., Greig, I. R., Thakur, G. A., Tichkule, R., Poklis, J., Ross, R. A., Pertwee, R. G. & Lichtman, A. H., Apr 2014, In : Behavioural Pharmacology. 25, 2, p. 182-185 4 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptor CB1
    Pharmacology
    rimonabant
    Dronabinol
    Appetite Depressants
    4 Citations (Scopus)

    Pyrazoles with a "click" 4-[N-(4-fluorobutyl)-1,2,3-triazole] substituent in position 3 are nanomolar CB1 receptor ligands

    Distinto, R., Zanato, C., Montanari, S., Cascio, M. G., Lazzari, P., Pertwee, R. & Zanda, M., Nov 2014, In : Journal of Fluorine Chemistry. 167, p. 184-191 8 p.

    Research output: Contribution to journalArticle

    rimonabant
    Pyrazoles
    Cannabinoid Receptor CB1
    Triazoles
    ligand
    5 Citations (Scopus)
    1 Downloads (Pure)

    Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist

    Brizzi, A., Aiello, F., Marini, P., Cascio, M. G., Corelli, F., Brizzi, V., De Petrocellis, L., Ligresti, A., Luongo, L., Lamponi, S., Maione, S., Pertwee, R. G. & Di Marzo, V., 1 Sep 2014, In : Behavioral and Brain Sciences. 22, 17, p. 4770-4783 14 p.

    Research output: Contribution to journalArticle

    Monoacylglycerol Lipases
    Ankyrins
    Cannabinoid Receptors
    Pharmacology
    Cannabinoid Receptor CB2
    2013
    131 Citations (Scopus)

    Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?

    Fernandez-Ruiz, J., Sagredo, O., Ruth Pazos, M., Garcia, C., Pertwee, R., Mechoulam, R. & Martinez-Orgado, J., Feb 2013, In : British Journal of Clinical Pharmacology. 75, 2, p. 323-333 11 p.

    Research output: Contribution to journalArticle

    64 Citations (Scopus)

    Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT(1A) receptor activation

    Bolognini, D., Rock, EM., Cluny, NL., Cascio, MG., Limebeer, CL., Duncan, M., Stott, CG., Javid, FA., Parker, LA. & Pertwee, RG., Mar 2013, In : British Journal of Pharmacology. 168, 6, p. 1456-1470 15 p.

    Research output: Contribution to journalArticle

    Receptor, Serotonin, 5-HT1A
    Nausea
    Vomiting
    Lithium Chloride
    Shrews
    84 Citations (Scopus)

    Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism

    Hill, T. D. M., Cascio, M-G., Romano, B., Duncan, M., Pertwee, R. G., Williams, C. M., Whalley, B. J. & Hill, A. J., Oct 2013, In : British Journal of Pharmacology. 170, 3, p. 679-692 14 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptor CB1
    Cannabis
    Anticonvulsants
    Seizures
    Pharmaceutical Preparations
    57 Citations (Scopus)

    Cannabinoids and omega-3/6 endocannabinoids as cell death and anticancer modulators

    Brown, I., Cascio, M. G., Rotondo, D., Pertwee, R. G., Heys, S. D. & Wahle, K. W. J., Jan 2013, In : Progress in Lipid Research. 52, 1, p. 80-109 30 p.

    Research output: Contribution to journalArticle

    Endocannabinoids
    Cannabinoids
    Cell death
    Modulators
    Cell Death
    75 Citations (Scopus)

    CB1 Receptor Allosteric Modulators Display Both Agonist and Signaling Pathway Specificity

    Baillie, G. L., Horswill, J. G., Anavi-Goffer, S., Reggio, P. H., Bolognini, D., Abood, M. E., McAllister, S., Strange, P. G., Stephens, G. J., Pertwee, R. G. & Ross, R. A., Feb 2013, In : Molecular Pharmacology. 83, 2, p. 322-338 17 p.

    Research output: Contribution to journalArticle

    13 Citations (Scopus)

    Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors

    Marini, P., Cascio, M. G., King, A., Pertwee, R. G. & Ross, R. A., Jun 2013, In : British Journal of Pharmacology. 169, 4, p. 887-899 13 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptor CB2
    Cannabinoid Receptors
    CHO Cells
    Ligands
    Spleen
    24 Citations (Scopus)

    Motor effects of the non-psychotropic phytocannabinoid cannabidiol that are mediated by 5-HT1A receptors

    Espejo-Porras, F., Fernandez-Ruiz, J., Pertwee, R. G., Mechoulam, R. & Garcia, C., Dec 2013, In : Neuropharmacology. 75, p. 155-163 9 p.

    Research output: Contribution to journalArticle

    65 Citations (Scopus)

    The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

    Romano, B., Borrelli, F., Fasolino, I., Capasso, R., Piscitelli, F., Cascio, M. G., Pertwee, R. G., Coppola, D., Vassallo, L., Orlando, P., Di Marzo, V. & Izzo, A. A., May 2013, In : British Journal of Pharmacology. 169, 1, p. 213-229 16 p.

    Research output: Contribution to journalArticle

    Ankyrins
    Cannabinoid Receptors
    Colitis
    Cannabinoid Receptor CB1
    Nitric Oxide
    2012
    33 Citations (Scopus)

    AM630 behaves as a protean ligand at the human cannabinoid CB2 receptor

    Bolognini, D., Cascio, M. G., Parolaro, D. & Pertwee, R. G., Apr 2012, In : British Journal of Pharmacology. 165, 8, p. 2561-2574 14 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptor CB2
    Ligands
    Cannabinoids
    CHO Cells
    Cell Membrane
    98 Citations (Scopus)

    Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus

    Rock, E. M., Bolognini, D., Limebeer, C. L., Cascio, M. G., Anavi-Goffer, S., Fletcher, P. J., Mechoulam, R., Pertwee, R. G. & Parker, L. A., Apr 2012, In : British Journal of Pharmacology. 165, 8, p. 2620-2634 15 p.

    Research output: Contribution to journalArticle

    Cannabidiol
    Autoreceptors
    Cannabis
    Nausea
    Vomiting
    26 Citations (Scopus)

    Delta(8)-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors

    Batkai, S., Mukhopadhyay, P., Horvath, B., Rajesh, M., Gao, R. Y., Mahadevan, A., Amere, M., Battista, N., Lichtman, A. H., Gauson, L. A., Maccarrone, M., Pertwee, R. G. & Pacher, P., Apr 2012, In : British Journal of Pharmacology. 165, 8, p. 2450-2461 12 p.

    Research output: Contribution to journalArticle

    14 Citations (Scopus)

    Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors

    Pasquini, S., De Rosa, M., Ligresti, A., Mugnaini, C., Brizzi, A., Caradonna, N. P., Cascio, M. G., Bolognini, D., Pertwee, R. G., Di Marzo, V. & Corelli, F., Dec 2012, In : European Journal of Medicinal Chemistry. 58, p. 30-43 14 p.

    Research output: Contribution to journalArticle

    23 Citations (Scopus)

    Investigations on the 4-Quinolone-3-Carboxylic Acid Motif Part 5: Modulation of the Physicochemical Profile of a Set of Potent and Selective Cannabinoid-2 Receptor Ligands through a Bioisosteric Approach

    Mugnaini, C., Nocerino, S., Pedani, V., Pasquini, S., Tafi, A., De Chiaro, M., Bellucci, L., Valoti, M., Guida, F., Luongo, L., Dragoni, S., Ligresti, A., Rosenberg, A., Bolognini, D., Cascio, M. G., Pertwee, R. G., Moaddel, R., Maione, S., Di Marzo, V. & Corelli, F., May 2012, In : ChemMedChem. 7, 5, p. 920-934 15 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptors
    Triazoles
    Cannabinoids
    Amides
    4-Quinolones
    69 Citations (Scopus)

    Modulation of L-α-lysophosphatidylinositol/GPR55 mitogen-activated protein kinase (MAPK) signaling by cannabinoids

    Anavi-Goffer, S., Baillie, G., Irving, A., Gertsch, J., Greig, I. R., Pertwee, R. G. & Ross, R. A., 2 Jan 2012, In : The Journal of Biological Chemistry. 287, 1, p. 91-104 15 p.

    Research output: Contribution to journalArticle

    62 Citations (Scopus)

    Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington's Disease: Role of CB1 and CB2 Receptors

    Valdeolivas, S., Satta, V., Pertwee, R. G., Fernandez-Ruiz, J. & Sagredo, O., 9 Feb 2012, In : ACS Chemical Neuroscience. 3, 5, p. 400-406 7 p.

    Research output: Contribution to journalArticle

    2011
    26 Citations (Scopus)

    Omega-3 N-acylethanolamines are endogenously synthesised from omega-3 fatty acids in different human prostate and breast cancer cell lines

    Brown, I., Wahle, K. W., Cascio, M. G., Smoum, R., Mechoulam, R., Pertwee, R. G. & Heys, S. D., Dec 2011, In : Prostaglandins, Leukotrienes and Essential Fatty Acids. 85, 6, p. 305-310 6 p.

    Research output: Contribution to journalArticle

    Omega-3 Fatty Acids
    Endocannabinoids
    Prostatic Neoplasms
    Cells
    Breast Neoplasms
    26 Citations (Scopus)

    Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist

    Wiley, J. L., Breivogel, C. S., Mahadevan, A., Pertwee, R. G., Cascio, M. G., Bolognini, D., Huffman, J. W., Walentiny, D. M., Vann, R. E., Razdan, R. K. & Martin, B. R., 25 Jan 2011, In : European Journal of Pharmacology. 651, 1-3, p. 96-105 10 p.

    Research output: Contribution to journalArticle

    Cannabinoids
    rimonabant
    Pharmacology
    Cannabinoid Receptor Agonists
    Sulfonamides
    2010
    25 Citations (Scopus)

    Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase

    Thors, L., Burston, J. J., Alter, B. J., McKinney, M. K., Cravatt, B. F., Ross, R. A., Pertwee, R. G., Gereau, R. W., Wiley, J. L. & Fowler, C. J., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 549-560 12 p.

    Research output: Contribution to journalArticle

    93 Citations (Scopus)

    Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines

    Brown, I., Cascio, M. G., Wahle, K. W. J., Smoum, R., Mechoulam, R., Ross, R. A., Pertwee, R. G. & Heys, S. D., Sep 2010, In : Carcinogenesis. 31, 9, p. 1584-1591 8 p.

    Research output: Contribution to journalArticle

    Cannabinoid Receptors
    Androgen Receptors
    Prostatic Neoplasms
    Cell Line
    Docosahexaenoic Acids
    71 Citations (Scopus)

    Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist

    Cascio, M. G., Gauson, L. A., Stevenson, L. A., Ross, R. A. & Pertwee, R. G., Jan 2010, In : British Journal of Pharmacology. 159, 1, p. 129-141 13 p.

    Research output: Contribution to journalArticle

    30 Citations (Scopus)

    Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.

    Pasquini, S., Ligresti, A., Mugnaini, C., Semeraro, T., Cicione, L., De Rosa, M., Guida, F., Luongo, L., De Chiaro, M., Cascio, M. G., Bolognini, D., Marini, P., Pertwee, R. G., Maione, S., Di Marzo, V. & Corelli, F., 26 Aug 2010, In : Journal of Medicinal Chemistry. 53, 16, p. 5915-5928 14 p.

    Research output: Contribution to journalArticle

    20 Citations (Scopus)

    In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB2 receptor inverse agonists

    Cascio, M. G., Bolognini, D., Pertwee, R. G., Palazzo, E., Corelli, F., Pasquini, S., Di Marzo, V. & Maione, S., Apr 2010, In : Pharmacological Research. 61, 4, p. 349-354 6 p.

    Research output: Contribution to journalArticle

    81 Citations (Scopus)

    Phytocannabinoids beyond the Cannabis plant - do they exist?

    Gertsch, J., Pertwee, R. G. & Di Marzo, V., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 523-529 7 p.

    Research output: Contribution to journalArticle

    62 Citations (Scopus)

    The effects of ¿9-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis

    Jamontt, J. M., Molleman, A., Pertwee, R. G. & Parsons, M. E., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 712-723 12 p.

    Research output: Contribution to journalArticle

    59 Citations (Scopus)

    The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

    Bolognini, D., Costa, B., Maione, S., Comelli, F., Marini, P., Di Marzo, V., Parolaro, D., Ross, R. A., Gauson, L. A., Cascio, M. G. & Pertwee, R. G., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 677-687 11 p.

    Research output: Contribution to journalArticle

    33 Citations (Scopus)

    WIN55,212-2 induced deficits in spatial learning are mediated by cholinergic hypofunction

    Robinson, L., Goonawardena, A. V., Pertwee, R. G., Hampson, R., Platt, B. & Riedel, G., 2 Apr 2010, In : Behavioural Brain Research. 208, 2, p. 584-592 9 p.

    Research output: Contribution to journalArticle

    2009
    121 Citations (Scopus)

    Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels

    Ryan, D., Drysdale, A. J., Lafourcade, C., Pertwee, R. G. & Platt, B., 18 Feb 2009, In : Journal of Neuroscience. 29, 7, p. 2053-2063 11 p.

    Research output: Contribution to journalArticle

    16 Citations (Scopus)

    Conformationally Constrained Fatty Acid Ethanolamides as Cannabinoid and Vanilloid Receptor Probes

    Appendino, G., Ligresti, A., Minassi, A., Cascio, M. G., Allara, M., Taglialatela-Scafati, O., Pertwee, R. G., De Petrocellis, L. & Di Marzo, V., 14 May 2009, In : Journal of Medicinal Chemistry. 52, 9, p. 3001-3009 9 p.

    Research output: Contribution to journalArticle

    69 Citations (Scopus)

    Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice

    Riedel, G., Fadda, P., McKillop-Smith, S., Pertwee, R. G., Platt, B. & Robinson, L., Apr 2009, In : British Journal of Pharmacology. 156, 7, p. 1154-1166 13 p.

    Research output: Contribution to journalArticle

    2008
    74 Citations (Scopus)

    Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis

    Croxford, J. L., Pryce, G., Jackson, S. J., Ledent, C., Giovannoni, G., Pertwee, R. G., Yamamura, T. & Baker, D., Jan 2008, In : Journal of Neuroimmunology. 193, 1-2, p. 120-129 10 p.

    Research output: Contribution to journalArticle