Roger Pertwee

Professor

    • 26727 Citations
    1970 …2020

    Research output per year

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    Research Output

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    Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice

    Riedel, G., Fadda, P., McKillop-Smith, S., Pertwee, R. G., Platt, B. & Robinson, L., Apr 2009, In : British Journal of Pharmacology. 156, 7, p. 1154-1166 13 p.

    Research output: Contribution to journalArticle

    71 Citations (Scopus)

    The bioactive conformation of aminoalkylindoles at the cannabinoid CB1 and CB2 receptors: Insights gained from (E)- and (Z)-naphthylidene indenes

    Reggio, P. H., Basu-Dutt, S., Barnett-Norris, J., Castro, M. T., Hurst, D. P., Seltzman, H. H., Roche, M. J., Gilliam, A. F., Thomas, B. F., Stevenson, L. A., Pertwee, R. G. & Abood, M. E., 1998, In : Journal of Medicinal Chemistry. 41, p. 5177-5187 11 p.

    Research output: Contribution to journalArticle

    60 Citations (Scopus)

    The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

    Romano, B., Borrelli, F., Fasolino, I., Capasso, R., Piscitelli, F., Cascio, M. G., Pertwee, R. G., Coppola, D., Vassallo, L., Orlando, P., Di Marzo, V. & Izzo, A. A., May 2013, In : British Journal of Pharmacology. 169, 1, p. 213-229 16 p.

    Research output: Contribution to journalArticle

    72 Citations (Scopus)

    The design, synthesis and testing of deoxy-CBD : further evidence for a region of steric interference at the cannabinoid receptor

    Reggio, P. H., Bramblett, R. D., Yuknavich, H., Seltzman, H. H., Fleming, D. N., Fernando, S. R., Stevenson, L. A. & Pertwee, R. G., 5 May 1995, In : Life Sciences. 56, 23-24, p. 2025-2032 8 p.

    Research output: Contribution to journalArticle

    13 Citations (Scopus)

    The effects of ¿9-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis

    Jamontt, J. M., Molleman, A., Pertwee, R. G. & Parsons, M. E., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 712-723 12 p.

    Research output: Contribution to journalArticle

    68 Citations (Scopus)

    The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice

    Al-Hayani, A., Wease, K., Ross, R. A., Pertwee, R. G. & Davies, S. N., Dec 2001, In : Neuropharmacology. 41, 8, p. 1000-1005 5 p.

    Research output: Contribution to journalArticle

    109 Citations (Scopus)
    6 Citations (Scopus)

    The perceived effects of smoked cannabis on patients with multiple sclerosis

    Consroe, P., Musty, R., Rein, J., Tillery, W. & Pertwee, R. G., 1997, In : European Journal of Neurology. 38, 1, p. 44-48 5 p.

    Research output: Contribution to journalArticle

    251 Citations (Scopus)

    The pharmacology of cannabinoid receptors and their ligands: an overview

    Pertwee, R. G., 2006, In : International Journal of Obesity. 30, Supplement 1, p. S13–S18 6 p.

    Research output: Contribution to journalArticle

    320 Citations (Scopus)

    The phytocannabinoid, Δ(9) -tetrahydrocannabivarin, can act through 5-HT1 A receptors to produce antipsychotic effects

    Cascio, M. G., Zamberletti, E., Marini, P., Parolaro, D. & Pertwee, R. G., Mar 2015, In : British Journal of Pharmacology. 172, 5, p. 1305-1318 14 p.

    Research output: Contribution to journalArticle

    Open Access
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    13 Citations (Scopus)
    5 Downloads (Pure)

    The plant cannabinoid Δ9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

    Bolognini, D., Costa, B., Maione, S., Comelli, F., Marini, P., Di Marzo, V., Parolaro, D., Ross, R. A., Gauson, L. A., Cascio, M. G. & Pertwee, R. G., Jun 2010, In : British Journal of Pharmacology. 160, 3, p. 677-687 11 p.

    Research output: Contribution to journalArticle

    62 Citations (Scopus)

    The psychoactive plant cannabinoid, Δ9-tetrahydrocannabinol, is antagonized by Δ8- and Δ9-tetrahydrocannabivarin in mice in vivo

    Pertwee, R. G., Thomas, A., Stevenson, L. A., Ross, R. A., Varvel, S. A., Lichtman, A. H., Martin, B. R. & Razdan, R. K., Mar 2007, In : British Journal of Pharmacology. 150, 5, p. 586-594 9 p.

    Research output: Contribution to journalArticle

    60 Citations (Scopus)
    171 Citations (Scopus)

    Thermoregulatory effects of N6-2'-0-dibutyryl adenosine-3',5'-monophosphate in the restrained mouse

    Dascombe, M. J., Milton, AS., Nyemiteiaddo, I. & Pertwee, R. G., 1980, In : British Journal of Pharmacology. 70, 3, p. 453-459 7 p.

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats

    Robinson, L., Goonawardena, A. V., Pertwee, R. G., Hampson, R. E. & Riedel, G., Jul 2007, In : British Journal of Pharmacology. 151, 5, p. 688-700 13 p.

    Research output: Contribution to journalArticle

    39 Citations (Scopus)

    Tricyclic fused pyrazoles with a 'Click' 1,2,3-triazole substituent in position 3 are nanomolar CB1 receptor ligands

    Zanato, C., Cascio, M. G., Lazzari, P., Pertwee, R., Testa, A. & Zanda, M., Mar 2015, In : Synthesis. 47, 6, p. 817-826 10 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    6 Citations (Scopus)
    16 Downloads (Pure)

    WIN55,212-2 induced deficits in spatial learning are mediated by cholinergic hypofunction

    Robinson, L., Goonawardena, A. V., Pertwee, R. G., Hampson, R., Platt, B. & Riedel, G., 2 Apr 2010, In : Behavioural Brain Research. 208, 2, p. 584-592 9 p.

    Research output: Contribution to journalArticle

    34 Citations (Scopus)