Photo of Sadaf Ashraf

Sadaf Ashraf

Dr

    • AB25 2ZD

    • 202 Citations
    20132019
    If you made any changes in Pure these will be visible here soon.

    Personal profile

    Biography

    I graduated with a BSc Honours degree in Physiology and a postgraduate MSc degree in Immunology from Kings College London. I obtained my PhD from the University of Nottingham. Since then my postdoctoral research work has revolved around investigating the molecular pathogenesis of diseases in which inflammation and angiogenesis are core components. A significant proportion of my research has been on enhancing understanding of arthritis pain and improving its treatment. I am a member of the Arthritis and Regenerative Medicine team within the Aberdeen Centre for Arthritis and Musculoskeletal Health (ACAMH). 

    Research Overview:

    I am interested in investigating the interactions between the arthritic joint and the peripheral and central processing of painful inputs originating from the joint. My current research revolves around understanding the roles of stem cells in the pathophysiology of joint homeostasis, remodelling and repair, with a particular focus on how stem cells interact with nerves in the joint to control arthritic pain. 

    Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

    • 2 Similar Profiles
    Osteoarthritis Medicine & Life Sciences
    Arthralgia Medicine & Life Sciences
    Pain Medicine & Life Sciences
    Synovitis Medicine & Life Sciences
    Iodoacetates Medicine & Life Sciences
    Carrageenan Medicine & Life Sciences
    Inflammation Medicine & Life Sciences
    Joints Medicine & Life Sciences

    Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output 2013 2019

    • 202 Citations
    • 9 Article
    5 Downloads (Pure)

    CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularisation

    Ashraf, S., Bell, S., O'Leary, C., Canning, P., Micu, I., Fernandez, J. A., O'Hare, M., Barabas, P., McCauley, H., Brazil, D. P., Stitt, A. W., McGeown, J. G. & Curtis, T. M., 21 Mar 2019, In : JCI Insight. 4, 6, e122442.

    Research output: Contribution to journalArticle

    Open Access
    File
    Retinal Neovascularization
    Choroidal Neovascularization
    Calcium-Calmodulin-Dependent Protein Kinases
    Pathologic Neovascularization
    Intercellular Signaling Peptides and Proteins
    1 Citation (Scopus)

    Effects of carrageenan induced synovitis on joint damage and pain in a rat model of knee osteoarthritis

    Ashraf, S., Mapp, P. I., Shahtaheri, S. M. & Walsh, D. A., 31 Oct 2018, In : Osteoarthritis and Cartilage. 26, 10, p. 1369-1378 10 p.

    Research output: Contribution to journalArticle

    Synovitis
    Knee Osteoarthritis
    Carrageenan
    Arthralgia
    Osteoarthritis
    12 Citations (Scopus)
    3 Downloads (Pure)

    Targeting the D Series Resolvin Receptor System for the Treatment of Osteoarthritis Pain

    Huang, J., Burston, J. J., Li, L., Ashraf, S., Mapp, P. I., Bennett, A. J., Ravipati, S., Pousinis, P., Barrett, D. A., Scammell, B. E. & Chapman, V., May 2017, In : Arthritis & Rheumatology. 69, 5, p. 996-1008 13 p.

    Research output: Contribution to journalArticle

    Open Access
    File
    Osteoarthritis
    Pain
    Therapeutics
    Arthralgia
    Pathology
    10 Citations (Scopus)
    3 Downloads (Pure)

    Selective inhibition of tropomyosin-receptor-kinase A (TrkA) reduces pain and joint damage in two rat models of inflammatory arthritis

    Ashraf, S., Bouhana, K. S., Pheneger, J., Andrews, S. W. & Walsh, D. A., 4 May 2016, In : Arthritis Research & Therapy. 18, 1, 11 p., 97.

    Research output: Contribution to journalArticle

    Open Access
    File
    Arthralgia
    Arthritis
    Experimental Arthritis
    Carrageenan
    Nerve Growth Factor

    Editorial: voltage-gated calcium 2.2 channels: therapeutic target for chronic arthritic pain?

    Ashraf, S., Jun 2015, In : Arthritis & Rheumatology. 67, 6, p. 1416-1418 3 p.

    Research output: Contribution to journalArticle