• 374 Citations
20112020

Research output per year

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Research Output

  • 374 Citations
  • 30 Article
2020

[18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

De Dominicis, C., Perrotta, P., Dall'angelo, S., Wyffels, L., Staelens, S., de Meyer, G. R. Y. & Zanda, M., 14 May 2020, In : ACS Medicinal Chemistry Letters. 11, 5, p. 933-939 7 p.

Research output: Contribution to journalArticle

A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

Schaefer, K., Dambuza, I. M., Dall'angelo, S., Trembleau, L., Zanda, M., Brown, G. D., Netea, M. G. & Gow, N. A. R., 17 Jul 2020, In : Microorganisms. 8, 7, 14 p., 1066.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers

Longo, B., Zanato, C., Piras, M., Dall'angelo, S., Windhorst, A. D., Vugts, D., Baldassarre, M. & Zanda, M., 30 Jul 2020, In : Bioconjugate Chemistry.

Research output: Contribution to journalArticle

Design, synthesis, radiosynthesis and biological evaluation of Fenretinide analogues as anticancer and metabolic syndromepreventive agents

Zanda, M., Patruno, I., Thompson, D., Dall'angelo, S., Windhorst, A. D., Vugts, D. J., Poot, A. J. & Mody, N., 9 Jul 2020, In : ChemMedChem. 13 p.

Research output: Contribution to journalArticle

Open Access

Hypoxia PET/CT and Colorectal Cancer: A Case Report

Laws, K., Zanda, M., Dall'angelo, S., McKiddie, F., Kerr, K., Murray, G. I., Fleming, I. & Samuel, L., 29 Jul 2020, (Accepted/In press) In : Journal of Case Reports and Images in Oncology.

Research output: Contribution to journalArticle

Open Access
2019

Enzymatic radiosynthesis of a 18F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)

Lowe, P. T., Dall'Angelo, S., Fleming, I. N., Piras, M., Zanda, M. & O'Hagan, D., 2019, In : Organic & Biomolecular Chemistry. 17, 6, p. 1480-1486 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
3 Downloads (Pure)

The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs)

Tseng, C-C., Baillie, G., Donvito, G., Mustafa, M. A., Juola, S. E., Zanato, C., Massarenti, C., Dall'angelo, S., Harrison, W. T. A., Lichtman, A. H., Ross, R. A., Zanda, M. & Greig, I. R., 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5049-5062 14 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
3 Downloads (Pure)
2018
Open Access
File
9 Citations (Scopus)
9 Downloads (Pure)

Enzymatic Fluorination of Biotin and Tetrazine Conjugates for Pretargeting Approaches to Positron Emission Tomography Imaging

Lowe, P. T., Dall'angelo, S., Devine, A., Zanda, M. & O'Hagan, D., 17 Sep 2018, In : ChemBioChem. 19, 18, p. 1969-1978 10 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
3 Downloads (Pure)

Preclinical Evaluation of [18F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters

Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A., Elmore, C. S., Dawson, D., Sharma, P. & Zanda, M., 30 Jul 2018, In : Contrast Media & Molecular Imaging. 2018, 10 p., 3064751.

Research output: Contribution to journalArticle

Open Access
File
10 Downloads (Pure)
2017

A New Class of Fluorinated A2A Adenosine Receptor Agonist with Application to Last-Step Enzymatic 18F Fluorination for PET Imaging

Lowe, P. T., Dall'Angello, S., Mulder-Krieger, T., Ijzerman, A. P., Zanda, M. & O'Hagan, D., 2 Nov 2017, In : ChemBioChem. 18, 21, p. 2156-2164 9 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
9 Downloads (Pure)

Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters

Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A. E., Elmore, C. S., Sharma, P. & Zanda, M., 1 Feb 2017, In : Bioorganic & Medicinal Chemistry. 25, 3, p. 963-976 14 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
9 Downloads (Pure)

High Affinity “Click” RGD Peptidomimetics as Radiolabeled Probes for Imaging αvβ3 Integrin

Piras, M., Testa, A., Fleming, I. N., Dall'Angelo, S., Andriu, A., Menta, S., Mori, M., Brown, G. D., Forster, D., Williams, K. J. & Zanda, M., 20 Jul 2017, In : ChemMedChem. 12, 14, p. 1142-1151 10 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
8 Downloads (Pure)

Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers

Zanato, C., Pelagalli, A., Marwick, K. F. M., Piras, M., Dall'Angelo, S., Spinaci, A., Pertwee, R. G., Wyllie, D. J. A., Hardingham, G. E. & Zanda, M., 2017, In : Organic & Biomolecular Chemistry. 15, 9, p. 2086-2096 11 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
9 Downloads (Pure)

Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by (1)H NMR spectroscopy

Fernandez Diaz-Rullo, F., Zamberlan, F., Mewis, R. E., Fekete, M., Broche, L., Cheyne, L. A., Dall'Angelo, S., Duckett, S. B., Dawson, D. & Zanda, M., 15 May 2017, In : Bioorganic & Medicinal Chemistry. 25, 10, p. 2730-2742 13 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
6 Downloads (Pure)

Synthesis and radio-synthesis of prospective 2-nitroimidazole hypoxia PET tracers via thiazolidine ligation with 5-fluorodeoxyribose (FDR)

Musolino, M., Dall'angelo, S. & Zanda, M., 2017, In : SynOpen. 1, 1, p. 173-179 7 p.

Research output: Contribution to journalArticle

Open Access
File
6 Downloads (Pure)

Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline

Sani, M., Lazzari, P., Folini, M., Spiga, M., Zuco, V., De Cesare, M., Manca, I., Dall'Angelo, S., Frigerio, M., Usai, I., Testa, A., Zaffaroni, N. & Zanda, M., 27 Apr 2017, In : Chemistry : a European Journal. 23, 24, p. 5842-5850 9 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
8 Downloads (Pure)
2016

Last-step enzymatic [18F]-fluorination of cysteine-tethered RGD peptides using modified Barbas linkers

Zhang, Q., Dall'Angelo, S., Fleming, I. N., Schweiger, L. F., Zanda, M. & O'Hagan, D., 25 Jul 2016, In : Chemistry : a European Journal. 22, 31, p. 10998-11004 7 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
7 Downloads (Pure)

NGR Tumor-Homing Peptides: Structural Requirements for Effective APN (CD13) Targeting

Graziadio, A., Zanda, M., Frau, S., Fleming, I. N., Musolino, M., Dall'Angelo, S., Baldassarre, M. & Piras, M., 18 May 2016, In : Bioconjugate Chemistry. 27, 5, p. 1332-1340 9 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
7 Downloads (Pure)
2015

An Efficient Route to N-Monosubstituted Guanidino-Lactams

Tommasi, S., Zanato, C., Carabeo, R., Mangoni, A., Dall'Angelo, S. & Zanda, M., Oct 2015, In : Synthesis. 47, 19, p. 3067-3078 12 p., ss-2015-n0113-op.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
8 Downloads (Pure)

Arginine Analogues Incorporating Carboxylate Bioisosteric Functions are Micromolar Inhibitors of Human Recombinant DDAH-1

Tommasi, S., Zanato, C., Lewis, B. C., Nair, P. C., Dall'Angelo, S., Zanda, M. & Mangoni, A. A., 14 Dec 2015, In : Organic & Biomolecular Chemistry. 46, 13, p. 11315-11330 16 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2013

18F-barbiturates are PET tracers with diagnostic potential in Alzheimer's disease

Calamai, E., Dall'Angelo, S., Koss, D., Domarkas, J., McCarthy, T. J., Mingarelli, M., Riedel, G., Schweiger, L. F., Welch, A. E., Platt, B. & Zanda, M., 2013, In : Chemical Communications. 49, 8, p. 792-794 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Efficient bioconjugation of 5-fluoro-5-deoxy-ribose (FDR) to RGD peptides for positron emission tomography (PET) imaging of αvβ3 integrin receptor

Dall'angelo, S., Zhang, Q., Fleming, I. N., Piras, M., Schweiger, L. F., O'Hagan, D. & Zanda, M., 3 Jun 2013, In : Organic & Biomolecular Chemistry. 27, 11, p. 4551-4558 8 p.

Research output: Contribution to journalArticle

Open Access
File
42 Downloads (Pure)

Molecular insights into bacteroid development during Rhizobium-legume symbiosis

Haag, A. F., Arnold, M. F. F., Myka, K. K., Kerscher, B., Dall'angelo, S., Zanda, M., Mergaert, P. & Ferguson, G. P., May 2013, In : FEMS Microbiology Reviews. 37, 3, p. 364-383 20 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Pyrazole-type Cannabinoid Ligands conjugated with Fluoro-deoxy-carbohydrates as Potential PET-Imaging Agents: Synthesis and CB1/CB2 receptor affinity evaluation

Frau, S., Dall'Angelo, S., Baillie, G. L., Ross, R. A., Pira, M., Tseng, C-C., Lazzari, P. & Zanda, M., Aug 2013, In : Journal of Fluorine Chemistry. 152, p. 166-172 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Tumour imaging by Positron Emission Tomography using fluorinase generated 5-[18F]fluoro-5-deoxyribose as a novel tracer

Dall'Angelo, S., Bandaranayaka, N., Windhorst, A. D., Vugts, D., van der Born, D., Onega, M., Schweiger, L. F., Zanda, M. & O'Hagan, D., May 2013, In : Nuclear Medicine and Biology. 40, 4, p. 464-470 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2012

[18F]-5-Fluoro-5-deoxyribose, an efficient peptide bioconjugation ligand for positron emission tomography (PET) imaging

Li, X. G., Dall'Angelo, S., Schweiger, L. F., Zanda, M. & O'Hagan, D., 28 May 2012, In : Chemical Communications. 48, 43, p. 5247-5249 3 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Role of cysteine residues and disulfide bonds in the activity of a legume root nodule-specific, cysteine-rich peptide

Haag, A. F., Kerscher, B., Dall'Angelo, S., Sani, M., Longhi, R., Baloban, M., Wilson, H. M., Mergaert, P., Zanda, M. & Ferguson, G. P., 30 Mar 2012, In : The Journal of Biological Chemistry. 287, 14, p. 10791-10798 8 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2011

Protection of Sinorhizobium against host cysteine-rich antimicrobial peptides is critical for symbiosis

Haag, A. F., Baloban, M., Sani, M., Kerscher, B., Pierre, O., Farkas, A., Longhi, R., Boncompagni, E., Hérouart, D., Dall'angelo, S., Kondorosi, E., Zanda, M., Mergaert, P. & Ferguson, G. P., 4 Oct 2011, In : PLoS Biology. 9, 10, 10 p., e1001169.

Research output: Contribution to journalArticle

99 Citations (Scopus)