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Research Output 1994 2019

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Article
2019
1 Citation (Scopus)

Human RIF1-Protein Phosphatase 1 prevents degradation and breakage of nascent DNA on replication stalling

Garzón, J., Ursich, S., Lopes, M., Hiraga, S. & Donaldson, A. D., 28 May 2019, In : Cell Reports. 27, 9, p. 2558-2566 13 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
DNA Replication
Degradation
DNA
Genomic Instability
2018
6 Citations (Scopus)
5 Downloads (Pure)

Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks

Hiraga, S., Monerawela, C., Katou, Y., Shaw, S., Clark, K. R. M., Shirahige, K. & Donaldson, A. D., 1 Sep 2018, In : EMBO reports. 19, 9, p. 1-14 14 p., e46222.

Research output: Contribution to journalArticle

Open Access
File
Saccharomycetales
Replication Origin
Hydroxyurea
Yeast
DNA Replication
6 Citations (Scopus)
5 Downloads (Pure)

Rif1 acts through Protein Phosphatase 1 but independent of replication timing to suppress telomere extension in budding yeast

Kedziora, S., Gali, V. K., Wilson, R. H. C., Clark, K. R. M., Nieduszynski, C. A., Hiraga, S. & Donaldson, A. D., 4 May 2018, In : Nucleic Acids Research. 46, 8, p. 3993-4003 11 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
Saccharomycetales
Telomere
Replication Origin
Telomere Homeostasis
2017
35 Citations (Scopus)
5 Downloads (Pure)

Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation

Hiraga, S., Ly, T., Garzon, J., Hořejší, Z., Ohkubo, Y., Endo, A., Obuse, C., Boulton, S. J., Lamond, A. I. & Donaldson, A. D., 1 Mar 2017, In : EMBO reports. 18, 3, p. 403-419 17 p., e201641983.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
Replication Origin
Licensure
DNA Replication
Chemical activation
2014
109 Citations (Scopus)
34 Downloads (Pure)

Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex

Hiraga, S., Alvino, G. M., Chang, F., Lian, H., Sridhar, A., Kubota, T., Brewer, B. J., Weinreich, M., Raghuraman, M. K. & Donaldson, A. D., 15 Feb 2014, In : Genes & Development. 28, 4, p. 372-383 12 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Phosphatase 1
DNA Replication
Phosphorylation
Phosphotransferases
Saccharomycetales
2012
12 Citations (Scopus)

Quantitative proteomic analysis of yeast DNA replication proteins

Kubota, T., Stead, D. A., Hiraga, S., ten Have, S. & Donaldson, A. D., Jun 2012, In : Methods. 57, 2, p. 196-202 7 p.

Research output: Contribution to journalArticle

DNA Replication
Proteomics
Yeast
Chromatin
Yeasts
16 Citations (Scopus)
3 Downloads (Pure)

TFIIIC Localizes Budding Yeast ETC Sites to the Nuclear Periphery

Hiraga, S., Botsios, S., Donze, D. & Donaldson, A. D., 15 Jul 2012, In : Molecular Biology of the Cell. 23, 14, p. 2741-2754 14 p.

Research output: Contribution to journalArticle

Open Access
File
Saccharomycetales
Saccharomyces cerevisiae
transcription factor TFIIIC
Chromatin
RNA Polymerase III
2011
37 Citations (Scopus)
4 Downloads (Pure)

Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint

Kubota, T., Hiraga, S., Yamada, K., Lamond, A. I. & Donaldson, A. D., 1 Jul 2011, In : Molecular and Cellular Proteomics. 10, 7, M110 005561.

Research output: Contribution to journalArticle

Open Access
File
DNA Replication
Proteomics
Chromatin
Replication Protein C
DNA
52 Citations (Scopus)
4 Downloads (Pure)

The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation

Lian, H., Robertson, E. D., Hiraga, S., Alvino, G. M., Collingwood, D., McCune, H. J., Sridhar, A., Brewer, B. J., Raghuraman, M. K. & Donaldson, A. D., 15 May 2011, In : Molecular Biology of the Cell. 22, 10, p. 1753-1756 4 p.

Research output: Contribution to journalArticle

Open Access
File
Telomere
Acetylation
Histones
Genome Components
Replication Origin
2010
23 Citations (Scopus)
3 Downloads (Pure)

Early initiation of a replication origin tethered at the nuclear periphery

Ebrahimi, H., Robertson, E. D., Taddei, A., Gasser, S. M., Donaldson, A. D. & Hiraga, S-I., 23 Mar 2010, In : Journal of Cell Science. 123, p. 1015-1019

Research output: Contribution to journalArticle

Open Access
File
Replication Origin
Single-Cell Analysis
Saccharomycetales
S Phase
Isotopes
2008
25 Citations (Scopus)
6 Downloads (Pure)

Histone H3 lysine 56 acetylation by Rtt109 is crucial for chromosome positioning

Hiraga, S-I., Botsios, S. & Donaldson, A. D., 17 Nov 2008, In : Journal of Cell Biology. 183, 4, p. 641-651 11 p.

Research output: Contribution to journalArticle

Open Access
File
2007
3 Downloads (Pure)

OriDB: a DNA replication origin database

Nieduszynski, C. A., Hiraga, S-I., Ak, P., Benham, C. J. & Donaldson, A. D., Jan 2007, In : Nucleic Acids Research. 35, Database Issue, p. D40-D46 7 p.

Research output: Contribution to journalArticle

Open Access
File
Replication Origin
DNA Replication
Databases
Chromosomes
Genome
2006
38 Citations (Scopus)
1 Downloads (Pure)

The Ctf18 RFC-like complex positions yeast telomeres but does not specify their replication time

Hiraga, S-I., Robertson, E. D. & Donaldson, A. D., Apr 2006, In : EMBO Journal. 25, 7, p. 1505-1514 9 p.

Research output: Contribution to journalArticle

File
2005

DNA polymerases alpha, delta, and epsilon localize and function together at replication forks in Saccharomyces cerevisiae

Hiraga, SI., Hagihara-Hayashi, A., Ohya, T. & Sugino, A., Apr 2005, In : Genes to Cells. 10, 4, p. 297-309 13 p.

Research output: Contribution to journalArticle

DNA Polymerase II
DNA Polymerase III
DNA Polymerase I
S Phase
Saccharomyces cerevisiae
2002

The DNA polymerase domain of pole is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae

Ohya, T., Kawasaki, Y., Hiraga, SI., Kanbara, S., Nakajo, K., Nakashima, N., Suzuki, A. & Sugino, A., 2 Aug 2002, In : Journal of Biological Chemistry. 277, 31, p. 28099-28108 11 p.

Research output: Contribution to journalArticle

Telomere Homeostasis
Cell Aging
DNA-Directed DNA Polymerase
DNA Replication
Yeast

The fifth essential DNA polymerase phi in Saccharomyces cerevisiae is localized to the nucleolus and plays an important role in synthesis of rRNA

Shimizu, K., Kawasaki, Y., Hiraga, SI., Tawaramoto, M., Nakashima, N. & Sugino, A., 9 Jul 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 14, p. 9133-9138 6 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Saccharomyces cerevisiae
Temperature
Yeasts
Aphidicolin
2000
Origin Recognition Complex
DNA Replication
Saccharomyces cerevisiae
Chromatin
Cell Cycle
1994
56 Citations (Scopus)

Comparative analysis of the replicon regions of eleven ColE2-related plasmids

Hiraga, S-I., Sugiyama, T. & Itoh, T., 1994, In : Journal of Bacteriology. 176, 23, p. 7233-7243 11 p.

Research output: Contribution to journalArticle

Replicon
Plasmids
Antisense RNA
Proteins
DNA Replication