• 826 Citations
20132019
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Research Output 2013 2019

  • 826 Citations
  • 26 Article
  • 1 Editorial
2019

Accuracy of the short-form Montreal Cognitive Assessment: Systematic review and validation

McDicken, J. A., Elliott, E., Blayney, G., Makin, S., Ali, M., Larner, A. J., Quinn, T. J. & Collaborators, VISTA-C., Oct 2019, In : The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 34, 10, p. 1515-1525 11 p.

Research output: Contribution to journalArticle

Stroke
Dementia
Sensitivity and Specificity
Research Personnel
Databases

Association between Striatal Brain Iron Deposition, Microbleeds and Cognition 1 Year After a Minor Ischaemic Stroke

Valdes Hernandez, M. D. C. V., Case, T., Chappell, F. M., Glatz, A., Makin, S., Doubal, F. & Wardlaw, J. M., 14 Mar 2019, In : International Journal of Molecular Sciences. 20, 6, 1293.

Research output: Contribution to journalArticle

Open Access
File
Iron deposits
cognition
Corpus Striatum
strokes
Cognition
8 Citations (Scopus)

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies

Wilson, D., Ambler, G., Lee, K-J., Lim, J-S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sánchez, L., Martínez-Domeño, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., Lam, B. Y. K. & 291 others, Wong, A., Kim, Y. D., Song, T-J., Schrooten, M., Lemmens, R., Eppinger, S., Gattringer, T., Uysal, E., Tanriverdi, Z., Bornstein, N. M., Assayag, E. B., Hallevi, H., Tanaka, J., Hara, H., Coutts, S. B., Hert, L., Polymeris, A., Seiffge, D. J., Lyrer, P., Algra, A., Kappelle, J., Al-Shahi Salman, R., Jäger, H. R., Lip, G. Y. H., Mattle, H. P., Panos, L. D., Mas, J-L., Legrand, L., Karayiannis, C., Phan, T., Gunkel, S., Christ, N., Abrigo, J., Leung, T., Chu, W., Chappell, F., Makin, S., Hayden, D., Williams, D. J., Kooi, M. E., van Dam-Nolen, D. H. K., Barbato, C., Browning, S., Wiegertjes, K., Tuladhar, A. M., Maaijwee, N., Guevarra, C., Yatawara, C., Mendyk, A-M., Delmaire, C., Köhler, S., van Oostenbrugge, R., Zhou, Y., Xu, C., Hilal, S., Gyanwali, B., Chen, C., Lou, M., Staals, J., Bordet, R., Kandiah, N., de Leeuw, F-E., Simister, R., van der Lugt, A., Kelly, P. J., Wardlaw, J. M., Soo, Y., Fluri, F., Srikanth, V., Calvet, D., Jung, S., Kwa, V. I. H., Engelter, S. T., Peters, N., Smith, E. E., Yakushiji, Y., Orken, D. N., Fazekas, F., Thijs, V., Heo, J. H., Mok, V., Veltkamp, R., Ay, H., Imaizumi, T., Gomez-Anson, B., Lau, K. K., Jouvent, E., Rothwell, P. M., Toyoda, K., Bae, H-J., Marti-Fabregas, J., Werring, D. J., Harkness, K., Shaw, L., Sword, J., Mohd Nor, A., Sharma, P., Kelly, D., Harrington, F., Randall, M., Smith, M., Mahawish, K., Elmarim, A., Esisi, B., Cullen, C., Nallasivam, A., Price, C., Barry, A., Roffe, C., Coyle, J., Hassan, A., Birns, J., Cohen, D., Sekaran, L., Parry-Jones, A., Parry, A., Hargroves, D., Proschel, H., Datta, P., Darawil, K., Manoj, A., Burn, M., Patterson, C., Giallombardo, E., Smyth, N., Mansoor, S., Anwar, I., Marsh, R., Ispoglou, S., Chadha, D., Prabhakaran, M., Meenakishundaram, S., O'Connell, J., Scott, J., Krishnamurthy, V., Aghoram, P., McCormick, M., Sprigg, N., O'Mahony, P., Cooper, M., Choy, L., Wilkinson, P., Leach, S., Caine, S., Burger, I., Gunathilagan, G., Guyler, P., Emsley, H., Davis, M., Manawadu, D., Pasco, K., Mamun, M., Luder, R., Sajid, M., Okwera, J., Warburton, E., Saastamoinen, K., England, T., Putterill, J., Flossman, E., Power, M., Dani, K., Mangion, D., Suman, A., Corrigan, J., Lawrence, E., Vahidassr, D., Shakeshaft, C., Brown, M., Charidimou, A., Cohen, H., Banerjee, G., Houlden, H., White, M., Yousry, T., Flossmann, E., Muir, K., El-Koussy, M., Gratz, P., Molad, J., Korczyn, A., Kliper, E., Maeder, P., Gass, A., Pachai, C., Bracoub, L., Douste-Blazy, M-Y., Fratacci, M. D., Vicaut, E., Sato, S., Miwa, K., Fujita, K., Ide, T., Ma, H., Ly, J., Singhal, S., Chandra, R., Slater, L-A., Soufan, C., Moran, C., Traenka, C., Thilemann, S., Fladt, J., Gensicke, H., Bonati, L., Kim, B. J., Han, M-K., Kang, J., Ko, E., Yang, M. H., Jang, M. S., Murphy, S., Carty, F., Akijian, L., Thornton, J., Schembri, M., Douven, E., Delgado, M., Escudero, R., Marín, R., Camps-Renom, P., Guisado-Alonso, D., Nuñez, F., Medrano-Martorell, S., Merino, E., Iida, K., Ikeda, S., Nishihara, M., Irie, H., Demirelli, D. S., Medanta, J. M., Zerna, C., Hernández, M. V., Armitage, P., Heye, A., Muñoz-Maniega, S., Sakka, E., Thrippleton, M., Dennis, M., Beigneux, Y., Silva, M., Venketasubramanian, N., Ho, S. L., Cheung, R. T. F., Chan, K. H., Teo, K. C., Hui, E., Kwan, J. S. K., Chang, R., Tse, M. Y., Hoi, C. P., Chan, C. Y., Chan, O. L., Cheung, R. H. K., Wong, E. K. M., Leung, K. T., Tsang, S. F., Ip, H. L., Ma, S. H., Ma, K., Fong, W. C., Li, S. H., Li, R., Ng, P. W., Wong, K. K., Liu, W., Wong, L., Ramos, L., De Schryver, E., Jöbsis, J., van der Sande, J., Brouwers, P., Roos, Y., Stam, J., Bakker, S., Verbiest, H., Schoonewille, W., Linn, C., Hertzberger, L., van Gemert, M., Berntsen, P., Hendrikse, J., Nederkoorn, P., Mess, W., Koudstaal, P., Leff, A., Ward, N., Nachev, P., Perry, R., Ozkan, H. & Mitchell, J., Jul 2019, In : The Lancet neurology. 18, 7, p. 653-665 13 p.

Research output: Contribution to journalArticle

Open Access
File
Transient Ischemic Attack
Cohort Studies
Stroke
Intracranial Hemorrhages
Neuroimaging

Comprehensive Geriatric Assessment in hospital and hospital-at-home settings: a mixed-methods study

Gardner, M., Shepperd, S., Godfrey, M., Mäkelä, P., Tsiachristas, A., Singh-Mehta, A., Ellis, G., Khanna, P., Langhorne, P., Makin, S. & Stott, D. J., Mar 2019, In : Health Serv Deliv Res. 7, 236 p.

Research output: Contribution to journalArticle

Open Access
File
Geriatric Assessment
Confidence Intervals
Propensity Score
Caregivers
Costs and Cost Analysis

Convolutional Neural Networks for Direct Inference of Pharmacokinetic Parameters: Application to Stroke Dynamic Contrast-Enhanced MRI

Ulas, C., Das, D., Thrippleton, M. J., Valdes Hernandez, M. D. C., Armitage, P. A., Makin, S. D., Wardlaw, J. M. & Menze, B. H., 8 Jan 2019, In : Frontiers in Neurology. 9, 1147.

Research output: Contribution to journalArticle

Open Access
File
Pharmacokinetics
Stroke
Neural Networks (Computer)
Least-Squares Analysis
Population Dynamics
6 Citations (Scopus)

Functional, cognitive and physical outcomes 3 years after minor lacunar or cortical ischaemic stroke

McHutchison, C. A., Cvoro, V., Makin, S., Chappell, F. M., Shuler, K. & Wardlaw, J. M., 2019, In : Journal of Neurology, Neurosurgery & Psychiatry. 90, 4, p. 436-443 8 p.

Research output: Contribution to journalArticle

Open Access
File
Stroke
Depression
Reading
National Institutes of Health (U.S.)
Ambulatory Care
1 Citation (Scopus)

Growing research in geriatric medicine

Witham, M. D., Roberts, H. C., Gladman, J., Stott, D. J., Sayer, A. A., Aspray, T. J., Brock, P., Clegg, A., Cox, N., Ewan, V., Frith, J., Burton, J. K., Jackson, T., Lewis, E. G., Lim, S. E., Makin, S., Lochlainn, M. N., Richardson, S., Shenkin, S. D., Steves, C. J. & 5 others, Todd, O., Tullo, E., Walker, R., Yarnall, A. & Extended Working Group from the NIHR Newcastle Biomedical Research Centre Meeting, May 2019, In : Age and Ageing. 48, 3, p. 316-319 4 p.

Research output: Contribution to journalArticle

Geriatrics
Medicine
Research
Research Personnel
Population
2 Citations (Scopus)

Identification of the presence of ischaemic stroke lesions by means of texture analysis on brain magnetic resonance images

Ortiz-Ramon, R., Valdes Hernandez, M. D. C., Gonzalez-Castro, V., Makin, S., Armitage, P. A., Aribisala, B. S., Bastin, M. E., Deary, I. J., Wardlaw, J. M. & Moratal, D., Jun 2019, In : Comput Med Imaging Graph. 74, p. 12-24 13 p.

Research output: Contribution to journalArticle

Open Access
File
Magnetic Resonance Spectroscopy
Stroke
Brain
Magnetic Resonance Imaging
Learning

Intensive Blood Pressure Lowering in Patients With Renal Impairment and Lacunar Stroke

Makin, S. & Whiteley, W. N., 20 Aug 2019, In : Journal of the American Heart Association. 8, 16, e013637.

Research output: Contribution to journalArticle

Open Access
File
Lacunar Stroke
Chronic Renal Insufficiency
Stroke
Blood Pressure
Hypertension

Stability of Estimated Premorbid Cognitive Ability over Time after Minor Stroke and Its Relationship with Post-Stroke Cognitive Ability

McHutchison, C. A., Chappell, F. M., Makin, S., Shuler, K., Wardlaw, J. M. & Cvoro, V., 22 May 2019, In : Brain Sciences. 9, 5, 117.

Research output: Contribution to journalArticle

Open Access
File
Aptitude
Stroke
Cognition
Education
Intelligence
4 Citations (Scopus)

The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study

Weaver, N. A., Zhao, L., Biesbroek, J. M., Kuijf, H. J., Aben, H. P., Bae, H. J., Caballero, M. A. A., Chappell, F. M., Chen, C., Dichgans, M., Duering, M., Georgakis, M. K., van der Giessen, R. S., Gyanwali, B., Hamilton, O. K. L., Hilal, S., Vom Hofe, E. M., de Kort, P. L. M., Koudstaal, P. J., Lam, B. Y. K. & 12 others, Lim, J. S., Makin, S. D. J., Mok, V. C. T., Shi, L., Valdes Hernandez, M. C., Venketasubramanian, N., Wardlaw, J. M., Wollenweber, F. A., Wong, A., Xin, X., Meta, V. C. I. M. C. & Biessels, G. J., Dec 2019, In : Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 11, p. 310-326 17 p.

Research output: Contribution to journalArticle

Open Access
File
Multicenter Studies
Blood Vessels
Meta-Analysis
Stroke
Sample Size
2018
12 Citations (Scopus)

Long-term morphological changes of symptomatic lacunar infarcts and surrounding white matter on structural magnetic resonance imaging

Loos, C. M. J., Makin, S. D. J., Staals, J., Dennis, M. S., Van Oostenbrugge, R. J. & Wardlaw, J. M., May 2018, In : Stroke. 49, 5, p. 1183-1188 6 p.

Research output: Contribution to journalArticle

Open Access
File
Lacunar Stroke
Magnetic Resonance Imaging
Cerebral Small Vessel Diseases
White Matter
Neuroimaging

Managing blood pressure in older adults: Age alone is no barrier to treatment

Makin, S. & Stott, D. J., 6 Jul 2018, In : BMJ (Online). 362, k2912.

Research output: Contribution to journalEditorial

Blood Pressure
Mortality
Independent Living
Therapeutics
Hypotension
5 Citations (Scopus)
1 Downloads (Pure)

The brain health index: Towards a combined measure of neurovascular and neurodegenerative structural brain injury

Dickie, D. A., Valdes Hernandez, M. D. C., Makin, S. D., Staals, J., Wiseman, S. J., Bastin, M. E. & Wardlaw, J. M., 1 Oct 2018, In : International Journal of Stroke. 13, 8, p. 849-856 8 p.

Research output: Contribution to journalArticle

Open Access
File
Brain Injuries
Health
Brain
Healthy Volunteers
Atrophy
2 Citations (Scopus)
Open Access
File
Sample Size
Blood Vessels
Stroke
Cognition
Therapeutics
5 Citations (Scopus)

The impact of early-life intelligence quotient on post stroke cognitive impairment

Makin, S. D. J., Doubal, F. N., Shuler, K., Chappell, F. M., Staals, J., Dennis, M. S. & Wardlaw, J. M., 1 Jun 2018, In : European Stroke Journal . 3, 2, p. 145-156 12 p.

Research output: Contribution to journalArticle

Open Access
Intelligence
Stroke
Odds Ratio
Confidence Intervals
Reading
2017
46 Citations (Scopus)

Blood-brain barrier failure as a core mechanism in cerebral small vessel disease and dementia: evidence from a cohort study

Wardlaw, J. M., Makin, S. J., Valdés Hernández, M. C., Armitage, P. A., Heye, A. K., Chappell, F. M., Muñoz-Maniega, S., Sakka, E., Shuler, K., Dennis, M. S. & Thrippleton, M. J., Jun 2017, In : Alzheimer's and Dementia. 13, 6, p. 634-643 10 p.

Research output: Contribution to journalArticle

Open Access
File
Cerebral Small Vessel Diseases
Blood-Brain Barrier
Dementia
Cohort Studies
Cognition
2016
24 Citations (Scopus)

Blood pressure and sodium: Association with MRI markers in cerebral small vessel disease

Heye, A. K., Thrippleton, M. J., Chappell, F. M., Hernandez Mdel, C., Armitage, P. A., Makin, S. D., Maniega, S. M., Sakka, E., Flatman, P. W., Dennis, M. S. & Wardlaw, J. M., 1 Jan 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, 1, p. 264-274 11 p.

Research output: Contribution to journalArticle

Cerebral Small Vessel Diseases
Salts
Sodium
Magnetic Resonance Imaging
Blood Pressure
73 Citations (Scopus)

Cerebral blood flow in small vessel disease: A systematic review and meta-analysis

Shi, Y., Thrippleton, M. J., Makin, S. D., Marshall, I., Geerlings, M. I., de Craen, A. J., van Buchem, M. A. & Wardlaw, J. M., 1 Oct 2016, In : Journal of Cerebral Blood Flow and Metabolism. 36, 10, p. 1653-1667 15 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Meta-Analysis
Accidental Falls
Cerebral Small Vessel Diseases
Cross-Sectional Studies
51 Citations (Scopus)

Tracer kinetic modelling for DCE-MRI quantification of subtle blood-brain barrier permeability

Heye, A. K., Thrippleton, M. J., Armitage, P. A., Valdes Hernandez, M. D. C., Makin, S. D., Glatz, A., Sakka, E. & Wardlaw, J. M., 15 Jan 2016, In : Neuroimage. 125, p. 446-455 10 p.

Research output: Contribution to journalArticle

Open Access
File
Blood-Brain Barrier
Permeability
Cerebral Small Vessel Diseases
Contrast Media
Healthy Volunteers
2015
30 Citations (Scopus)

A comparison of location of acute symptomatic vs. 'silent' small vessel lesions

Valdes Hernandez, M. D. C., Maconick, L. C., Munoz Maniega, S., Wang, X., Wiseman, S., Armitage, P. A., Doubal, F. N., Makin, S., Sudlow, C. L., Dennis, M. S., Deary, I. J., Bastin, M. & Wardlaw, J. M., Oct 2015, In : International Journal of Stroke. 10, 7, p. 1044-1050 7 p.

Research output: Contribution to journalArticle

Lacunar Stroke
Corpus Striatum
Stroke
Cerebral Small Vessel Diseases
Internal Capsule
34 Citations (Scopus)

Cerebral small vessel disease and renal function: systematic review and meta-analysis

Makin, S. D. J., Cook, F. A. B., Dennis, M. S. & Wardlaw, J. M., Jan 2015, In : Cerebrovascular Diseases. 39, 1, p. 39-52 14 p.

Research output: Contribution to journalArticle

Open Access
File
Cerebral Small Vessel Diseases
Meta-Analysis
Lacunar Stroke
Kidney
Stroke
47 Citations (Scopus)

Clinically Confirmed Stroke With Negative Diffusion-Weighted Imaging Magnetic Resonance Imaging: Longitudinal Study of Clinical Outcomes, Stroke Recurrence, and Systematic Review

Makin, S. D., Doubal, F. N., Dennis, M. S. & Wardlaw, J. M., 29 Sep 2015, In : Stroke. 46, 11, p. 3142-3148 7 p.

Research output: Contribution to journalArticle

Open Access
File
Longitudinal Studies
Stroke
Magnetic Resonance Imaging
Recurrence
Diffusion Magnetic Resonance Imaging
2013
100 Citations (Scopus)
Open Access
File
Lacunar Stroke
Meta-Analysis
Stroke
Incidence
Dementia
5 Citations (Scopus)

Dystypia in acute stroke not attributable to aphasia or neglect

Cook, F. A. B., Makin, S. D. J., Wardlaw, J. & Dennis, M. S., 2013, In : BMJ Case Reports. 2013, bcr2013200257.

Research output: Contribution to journalArticle

Aphasia
Handwriting
Aptitude
Stroke
Perceptual Disorders
34 Citations (Scopus)

Variation in risk factors for recent small subcortical infarcts with infarct size, shape, and location

Del Bene, A., Makin, S. D. J., Doubal, F. N., Inzitari, D. & Wardlaw, J. M., Nov 2013, In : Stroke. 44, 11, p. 3000-3006 7 p.

Research output: Contribution to journalArticle

Lacunar Stroke
Basal Ganglia
Stroke
Odds Ratio
Confidence Intervals