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Research Output

2020

Evolution of IFN subgroups in bony fish - 2. analysis of subgroup appearance and expansion in teleost fish with a focus on salmonids

Liu, F., Wang, T., Petit, J., Forlenza, M., Chen, X., Chen, L., Zou, J. & Secombes, C. J., Mar 2020, In : Fish & Shellfish Immunology. 98, p. 564-573 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Identification, molecular characterization and functional analysis of interleukin (IL)-2 and IL-2like (IL-2L) cytokines in sea bass (Dicentrarchus labrax L.)

Buonocore, F., Gerdol, M., Pallavicini, A., Stocchi, V., Randelli, E., Belardinelli, M. C., Miccoli, A., Saraceni, P. R., Secombes, C. J., Scapigliati, G. & Wang, T., Feb 2020, In : Cytokine. 126, 154898.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

An insight into piscidins: The discovery, modulation and bioactivity of greater amberjack, Seriola dumerili, piscidin

Milne, D. J., Fernández-Montero, Á., Gundappa, M. K., Wang, T., Acosta, F., Torrecillas, S., Montero, D., Zou, J., Sweetman, J. & Secombes, C. J., Oct 2019, In : Molecular Immunology. 114, p. 378-388 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Detection of interleukin (IL)-22 protein expression in rainbow trout (Oncorhynchus mykiss)

Hu, Y., Wang, T., Carpio, Y., Scott, C., Wang, T., Liu, F., Monte, M., Alnabulsi, A. & Secombes, C. J., Aug 2019, In : Fish & Shellfish Immunology. 91, p. 445 1 p.

Research output: Contribution to journalAbstract

4 Citations (Scopus)
1 Citation (Scopus)
Open Access
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9 Citations (Scopus)
4 Downloads (Pure)
2 Citations (Scopus)

Identification and characterization of three CXC chemokines in Asian swamp eel (Monopterus albus) uncover a third CXCL11_like group in fish

Yuan, H., Li, Y., Han, P., Tian, G., Zhang, W., Guo, H., Xu, Q. & Wang, T., Dec 2019, In : Developmental and Comparative Immunology. 101, 9 p., 103454.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Induction of IL-22 protein and IL-22-producing cells in rainbow trout Oncorhynchus mykiss

Hu, Y., Carpio, Y., Scott, C., Alnabulsi, A., Alnabulsi, A., Wang, T., Liu, F., Monte, M., Wang, T. & Secombes, C. J., Dec 2019, In : Developmental and Comparative Immunology. 101, 103449.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

Insights into the evolution of the suppressors of cytokine signalling (SOCS) gene family in vertebrates

Wang, B., Wangkahart, E., Secombes, C. J. & Wang, T., 1 Feb 2019, In : Molecular Biology and Evolution. 36, 2, p. 393-411 19 p.

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
4 Downloads (Pure)

Lineage/species-specific expansion of the Mx gene family in teleosts: Differential expression and modulation of nine Mx genes in rainbow trout Oncorhynchus mykiss

Wang, T., Liu, F., Tian, G., Secombes, C. J. & Wang, T., 1 Jul 2019, In : Fish & Shellfish Immunology. 90, p. 413-430 18 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Studies on the Use of Flagellin as an Immunostimulant and Vaccine Adjuvant in Fish Aquaculture

Wang, T. & Secombes, C. J., 9 Jan 2019, In : Frontiers in Immunology. 9, 3054.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
3 Downloads (Pure)

The transforming growth factor (TGF)-B family in rainbow trout (Oncorhynchus mykiss): Characterization and expression analysis

Wang, T., Liu, F., Hu, Y., Secombes, C. J. & Wang, T., Aug 2019, In : Fish & Shellfish Immunology. 91, p. 448 1 p.

Research output: Contribution to journalAbstract

2018

Characterisation of rainbow trout peripheral blood leucocytes prepared by hypotonic lysis of erythrocytes, and analysis of their phagocytic activity, proliferation and response to PAMPs and proinflammatory cytokines

Hu, Y., Maisey, K., Subramani, P. A., Liu, F., Flores-Kossack, C., Imarai, M., Secombes, C. J. & Wang, T., Nov 2018, In : Developmental and Comparative Immunology. 88, p. 104-113 10 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)

Characterisation of ZBTB46 and DC-SCRIPT/ZNF366 in rainbow trout, transcription factors potentially involved in dendritic cell maturation and activation in fish

Wang, J., Wang, T., Benedicenti, O., Collins, C., Wang, K., Secombes, C. J. & Zou, J., Mar 2018, In : Developmental and Comparative Immunology. 80, p. 2-14 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar

Chance, R. J., Cameron, G. A., Fordyce, M., Noguera, P., Wang, T., Collins, C., Secombes, C. J. & Collet, B., Dec 2018, In : Journal of Fish Biology. 93, 6, p. 1069-1081 13 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
7 Downloads (Pure)

Four selenoprotein P genes exist in salmonids: Analysis of their origin and expression following Se supplementation and bacterial infection

Pohl, M. A. N., Wang, T., Pohl, T., Sweetman, J., Martin, S. A. M. & Secombes, C. J., 20 Dec 2018, In : PloS ONE. 13, 12, e0209381.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
4 Downloads (Pure)

Gene expression analysis of isolated salmonid GALT leucocytes in response to PAMPs and recombinant cytokines

Attaya, A., Wang, T., Zou, J., Herath, T., Adams, A., Secombes, C. J. & Yoon, S., 1 Sep 2018, In : Fish & Shellfish Immunology. 80, p. 426-436 11 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
1 Downloads (Pure)

Immune-modulation of two BATF3 paralogues in rainbow trout Oncorhynchus mykiss 

Wang, J., Liu, M., Wu, Y., Yoon, S., Alnabulsi, A., Liu, F., Fernández-Álvarez, C., Wang, T., Holland, J. W., Secombes, C. J. & Zou, J., 1 Jul 2018, In : Molecular Immunology. 99, p. 104-114 11 p.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
4 Downloads (Pure)

Interleukin (IL)-2 Is a Key Regulator of T Helper 1 and T Helper 2 Cytokine Expression in Fish: Functional Characterization of Two Divergent IL2 Paralogs in Salmonids

Wang, T., Hu, Y., Wangkahart, E., Liu, F., Wang, A., Zahran, E., Maisey, K., Liu, M., Xu, Q., Imarai, M. & Secombes, C. J., 26 Jul 2018, In : Frontiers in Immunology. 9, 1683.

Research output: Contribution to journalArticle

Open Access
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18 Citations (Scopus)
17 Downloads (Pure)

Rainbow trout (Oncorhynchus mykiss) adipose tissue undergoes major changes in immune gene expression following bacterial infection or stimulation with pro-inflammatory molecules

Veenstra, K. A., Wangkahart, E., Wang, T., Tubbs, L., Ben Arous, J. & Secombes, C. J., Apr 2018, In : Developmental and Comparative Immunology. 81, p. 83-94 12 p.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
5 Downloads (Pure)
2017

Analysis of adipose tissue immune gene expression after vaccination of rainbow trout with adjuvanted bacterins reveals an association with side effects

Veenstra, K. A., Wang, T., Alnabulsi, A., Douglas, A., Russell, K. S., Tubbs, L., Arous, J. B. & Secombes, C. J., Aug 2017, In : Molecular Immunology. 88, p. 89-98 10 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
24 Downloads (Pure)

Characterisation of arginase paralogues in salmonids and their modulation by immune stimulation/ infection

Benedicenti, O., Wang, T., Wangkahart, E., Milne, D. J., Holland, J. W., Collins, C. & Secombes, C. J., Feb 2017, In : Fish & Shellfish Immunology. 61, p. 138-151 14 p.

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
6 Downloads (Pure)

Evolution of Th2 responses: Characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity

Stocchi, V., Wang, T., Randelli, E., Mazzini, M., Gerdol, M., Pallavicini, A., Secombes, C. J., Scapigliati, G. & Buonocore, F., 22 May 2017, In : Scientific Reports. 7, p. 1-15 15 p., 2240.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
5 Downloads (Pure)
Open Access
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4 Citations (Scopus)
3 Downloads (Pure)
2016

Characterisation of transcription factors in rainbow trout potentially involved in dendritic cell maturation and activation

Wang, J., Wang, T., Benedicenti, O., Collins, C., McCarthy, U., Wang, K., Secombes, C. J. & Zou, J., Jun 2016, In : Fish & Shellfish Immunology. 53, p. 74 1 p.

Research output: Contribution to journalAbstract

Characterization and expression analysis of chemokine-like receptor 3 gene in rainbow trout Oncorhynchus mykiss

Qi, Z., Zhang, Q., Holland, J. W., Gao, Q., Tafalla, C., Wang, X. & Wang, T., 1 Jul 2016, In : Reviews in Fisheries Science. 82, 4, p. 613-622 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

CK9, an ancient rainbow trout chemokine that attracts and regulates B lymphocytes, and macrophages

Aquilino, C., Granja, A. G., Castro, R., Wang, T., Abos, B., Parra, D., Secombes, C. J. & Tafalla, C., Jun 2016, In : Fish & Shellfish Immunology. 53, p. 82 1 p.

Research output: Contribution to journalAbstract

Cross Talk Between Growth and Immunity: Coupling of the IGF Axis to Conserved Cytokine Pathways in Rainbow Trout

Alzaid, A., Castro, R., Wang, T., Secombes, C. J., Boudinot, P., Macqueen, D. J. & Martin, S. A. M., 1 Apr 2016, In : Endocrinology. 157, 5, p. 1942–1955 13 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Differential effects of interleukin 6 and lipopolysaccharide on teleost B lymphocytes

Abos, B., Wang, T., Castro, R., Leal, E., Luque, A., Havixbeck, J., Barreda, D., Secombes, C. J. & Tafalla, C., Jun 2016, In : Fish & Shellfish Immunology. 53, SI, p. 72 1 p.

Research output: Contribution to journalAbstract

Distinct Differentiation Programs Triggered by IL-6 And LPS in Teleost IgM+ B Cells in the Absence of Germinal Centers

Abós, B., Wang, T., Castro, R., Granja, A. G., Leal, E., Havixbeck, J., Luque, A., Barreda, D. R., Secombes, C. J. & Tafalla, C., 2016, In : Scientific Reports. 6, p. 1-16 16 p., 30004.

Research output: Contribution to journalArticle

Open Access
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25 Citations (Scopus)
4 Downloads (Pure)

First in-depth analysis of the novel Th2-type cytokines in salmonid fish reveals distinct patterns of expression and modulation but overlapping bioactivities

Wang, T., Johansson, P., Abós, B., Holt, A., Tafalla, C., Jiang, Y., Wang, A., Xu, Q., Zhitao, Q., Huang, W., Costa, M. M., Diaz-Rosales, P., Holland, J. W. & Secombes, C. J., 9 Feb 2016, In : Oncotarget. 7, 10, p. 10917-10946 30 p., 7295.

Research output: Contribution to journalArticle

Open Access
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54 Citations (Scopus)
6 Downloads (Pure)

Growth and immunity cross-talk in rainbow trout: Suppression of the insulin-like growth factor system during infection

Alzaid, A., Castro, R., Wang, T., Secombes, C. J., Boudinot, P., Macqueen, D. J. & Martin, S. A. M., Jun 2016, In : Fish & Shellfish Immunology. 53, p. 111 1 p.

Research output: Contribution to journalAbstract

Identification and expression modulation of a C-type lectin domain family 4 homologue that is highly expressed in monocytes/macrophages in rainbow trout (Oncorhynchus mykiss)

Johansson, P., Wang, T., Collet, B., Corripio-Miyar, Y., Monte, M. M., Secombes, C. J. & Zou, J., Jan 2016, In : Developmental and Comparative Immunology. 54, 1, p. 55-65 11 p.

Research output: Contribution to journalArticle

Open Access
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15 Citations (Scopus)
7 Downloads (Pure)

Immune gene profiling of different gut regions and gut associated lymphoid cells from rainbow trout (Oncorhynchus mykiss)

Yoon, S., Attaya, A., Wang, T., Zou, J. & Secombes, C. J., Jun 2016, In : Fish & Shellfish Immunology. 53, p. 112 1 p.

Research output: Contribution to journalAbstract

Impact of selenium supplementation on fish antiviral responses: a whole transcriptomic analysis in rainbow trout (Oncorhynchus mykiss) fed supranutritional levels of Sel-Plex®

Pacitti, D., Lawan, M. M., Feldmann, J., Sweetman, J., Wang, T., Martin, S. A. M. & Secombes, C. J., 16 Feb 2016, In : BMC Genomics. 17, p. 1-26 26 p., 116.

Research output: Contribution to journalArticle

Open Access
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30 Citations (Scopus)
7 Downloads (Pure)

Isolation and Characterization of Salmonid CD4+ T Cells

Maisey, K., Montero, R., Corripio-Miyar, Y., Toro-Ascuy, D., Valenzuela, B., Reyes-Cerpa, S., Sandino, A. M., Zou, J., Wang, T., Secombes, C. J. & Imarai, M., May 2016, In : The Journal of Immunology. 196, 10, p. 4150-4163 14 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Macrophage migration inhibitory factor (MIF) family in arthropods: Cloning and expression analysis of two MIF and one D-dopachrome tautomerase (DDT) homologues in Mud crabs, Scylla paramamosain

Huang, W-S., Duan, L-P., Huang, B., Wang, K-J., Zhang, C-L., Jia, Q., Nie, P. & Wang, T., Mar 2016, In : Fish & Shellfish Immunology. 50, p. 142-149 8 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
3 Downloads (Pure)

Rainbow trout CK9, a CCL25-like ancient chemokine that attracts and regulates B cells and macrophages, the main antigen presenting cells in fish

Aquilino, C., Granja, A. G., Castro, R., Wang, T., Abos, B., Parra, D., Secombes, C. J. & Tafalla, C., 17 Mar 2016, In : Oncotarget. 7, 14, p. 17547-17564 18 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
9 Downloads (Pure)
Open Access
File
29 Citations (Scopus)
6 Downloads (Pure)

Sequence and Expression Analysis of Interferon Regulatory Factor 10 (IRF10) in Three Diverse Teleost Fish Reveals Its Role in Antiviral Defense

Xu, Q., Jiang, Y., Wangkahart, E., Zou, J., Chang, M., Yang, D., Secombes, C. J., Nie, P. & Wang, T., 19 Jan 2016, In : PloS ONE. 11, 1, p. 1-22 22 p., 0147181.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
5 Downloads (Pure)

Vertebrate Cytokines and Their Evolution

Secombes, C. J., Wang, T. & Bird, S., 20 May 2016, The Evolution of the Immune System: Conservation and Diversification. Malagoli, D. (ed.). Academic Press, p. 87-150 64 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Citations (Scopus)
2015

Characterisation of the TNF superfamily members CD40L and BAFF in the small-spotted catshark (Scyliorhinus canicula)

Li, R., Redmond, A. K., Wang, T., Bird, S., Dooley, H. & Secombes, C. J., 1 Nov 2015, In : Fish & Shellfish Immunology. 47, 1, p. 381-389 9 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
38 Downloads (Pure)

Erratum to Role of pathogen-derived cell wall carbohydrates and prostaglandin E2 in immune response and suppression of fish immunity by the oomycete Saprolegnia parasitica

Belmonte, R., Wang, T., Duncan, G. J., Skaar, I., Mélida, H., Bulone, V., van West, P., Secombes, C. J. & Appleton, J. A. (ed.), Jan 2015, In : Infection and Immunity. 83, 1, p. 454 1 p.

Research output: Contribution to journalArticle

Identification and expression analysis of an atypical chemokine receptor-2 (ACKR2)/CC chemokine binding protein-2 (CCBP2) in rainbow trout (Oncorhynchus mykiss)

Qi, Z., Jiang, Y., Holland, J. W., Nie, P., Secombes, C. J. & Wang, T., Jun 2015, In : Fish & Shellfish Immunology. 44, 2, p. 389-398 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Identification and expression analysis of two interleukin-23α (p19) isoforms, in rainbow trout Oncorhynchus mykiss and Atlantic salmon Salmo salar

Jiang, Y., Husain, M., Qi, Z., Bird, S. & Wang, T., Aug 2015, In : Molecular Immunology. 66, 2, p. 216-228 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Identification of the salmonid IL-17A/F1a/b, IL-17A/F2b, IL-17A/F3 and IL-17N genes and analysis of their expression following in vitro stimulation and infection

Wang, T., Jiang, Y., Wang, A., Husain, M., Xu, Q. & Secombes, C. J., 1 Jul 2015, In : Immunogenetics. 67, 7, p. 395-412 18 p.

Research output: Contribution to journalArticle

Open Access
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31 Citations (Scopus)
4 Downloads (Pure)

Identification of three IFN-γ inducible lysosomal thiol reductase (GILT)-like genes in mud crab Scylla paramamosain with distinct gene organizations and patterns of expression

Huang, W. S., Duan, L. P., Huang, B., Zhou, L. H., Liang, Y., Tu, C. L., Zhang, F. F., Nie, P. & Wang, T., 1 Oct 2015, In : Gene. 570, 1, p. 78-88 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)