235. Evaluation of a nanosynthetic silicated calcium phosphate putty in a posterolateral rabbit spinal fusion model

William  Walsh; Rema Oliver; Tian Wang; Daniel  Wills; Jordan Conway; Thomas Buckland; Iain R Gibson

doi:10.1016/j.spinee.2020.05.646

235. Evaluation of a nanosynthetic silicated calcium phosphate putty in a posterolateral rabbit spinal fusion model

William Walsh, Rema Oliver, Tian Wang, Daniel Wills, Jordan Conway, Thomas Buckland, Iain R Gibson

Research output: Contribution to journal › Article › peer-review

Abstract

Providing surgeons with an “off the shelf” bone graft substitute to aid in bone healing is advantageous providing the materials participate in and facilitate the desired goal of fusion. Synthetic calcium phosphate-based (CaP) materials are excellent candidates considering their comparable composition to bone mineral however other factors have been shown to play a role in osteogenic behavior of these materials including surface chemistry and surface topography. The preclinical rabbit posterolateral fusion developed by Professor Boden provides a robust means to evaluate the in vivo performance of graft materials in this challenging indication.

Original language	English
Pages (from-to)	S116
Number of pages	1
Journal	The Spine Journal
Volume	20
Issue number	9
Early online date	9 Sep 2020
DOIs	https://doi.org/10.1016/j.spinee.2020.05.646
Publication status	Published - Sep 2020

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title = "235. Evaluation of a nanosynthetic silicated calcium phosphate putty in a posterolateral rabbit spinal fusion model",

abstract = "Providing surgeons with an “off the shelf” bone graft substitute to aid in bone healing is advantageous providing the materials participate in and facilitate the desired goal of fusion. Synthetic calcium phosphate-based (CaP) materials are excellent candidates considering their comparable composition to bone mineral however other factors have been shown to play a role in osteogenic behavior of these materials including surface chemistry and surface topography. The preclinical rabbit posterolateral fusion developed by Professor Boden provides a robust means to evaluate the in vivo performance of graft materials in this challenging indication.",

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AU - Oliver, Rema

AU - Wang, Tian

AU - Wills, Daniel

AU - Conway, Jordan

AU - Buckland, Thomas

AU - Gibson, Iain R

PY - 2020/9

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AB - Providing surgeons with an “off the shelf” bone graft substitute to aid in bone healing is advantageous providing the materials participate in and facilitate the desired goal of fusion. Synthetic calcium phosphate-based (CaP) materials are excellent candidates considering their comparable composition to bone mineral however other factors have been shown to play a role in osteogenic behavior of these materials including surface chemistry and surface topography. The preclinical rabbit posterolateral fusion developed by Professor Boden provides a robust means to evaluate the in vivo performance of graft materials in this challenging indication.

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DO - 10.1016/j.spinee.2020.05.646

M3 - Article

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SP - S116

JO - The Spine Journal

JF - The Spine Journal

IS - 9

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235. Evaluation of a nanosynthetic silicated calcium phosphate putty in a posterolateral rabbit spinal fusion model

Abstract

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