5-chloro-3-ethyl-N-[2-(morpholin-4-yl)ethyl]-1H-indole-2-carboxamide

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In the title compound, C17H22ClN3O2, the aromatic fused ring system and the amide group are close to being coplanar [dihedral angle = 14.66 (16)degrees]. Thus, the amide NH group is sterically blocked from forming a hydrogen bond by the pendant ethyl substituent of the adjacent five-membered ring. The NH group of the five-membered ring makes an intermolecular N-H center dot center dot center dot O bond, resulting in centrosymmetric dimers of molecules containing R-2(2)(10)loops.

Original languageEnglish
Article numbero3389
Number of pages11
JournalActa Crystallographica Section E: Structure Reports Online
Volume63
Issue number8
DOIs
Publication statusPublished - 1 Aug 2007

Keywords

  • X-ray
  • diffraction

Cite this

5-chloro-3-ethyl-N-[2-(morpholin-4-yl)ethyl]-1H-indole-2-carboxamide. / Muirhead, Kirsty E. A.; Trembleau, Laurent; Harrison, William T. A.

In: Acta Crystallographica Section E: Structure Reports Online, Vol. 63, No. 8, o3389, 01.08.2007.

Research output: Contribution to journalArticle

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AU - Muirhead, Kirsty E. A.

AU - Trembleau, Laurent

AU - Harrison, William T. A.

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N2 - In the title compound, C17H22ClN3O2, the aromatic fused ring system and the amide group are close to being coplanar [dihedral angle = 14.66 (16)degrees]. Thus, the amide NH group is sterically blocked from forming a hydrogen bond by the pendant ethyl substituent of the adjacent five-membered ring. The NH group of the five-membered ring makes an intermolecular N-H center dot center dot center dot O bond, resulting in centrosymmetric dimers of molecules containing R-2(2)(10)loops.

AB - In the title compound, C17H22ClN3O2, the aromatic fused ring system and the amide group are close to being coplanar [dihedral angle = 14.66 (16)degrees]. Thus, the amide NH group is sterically blocked from forming a hydrogen bond by the pendant ethyl substituent of the adjacent five-membered ring. The NH group of the five-membered ring makes an intermolecular N-H center dot center dot center dot O bond, resulting in centrosymmetric dimers of molecules containing R-2(2)(10)loops.

KW - X-ray

KW - diffraction

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DO - 10.1107/S1600536807031285

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JO - Acta Crystallographica Section E: Structure Reports Online

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