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  • Marcel Jaspars
2012

A combined atomic force microscopy and computational approach for the structural elucidation of Breitfussin A and B: highly modified halogenated dipeptides from Thuiaria breitfussi

Hanssen, K. O., Schuler, B., Williams, A. J., Demissie, T. B., Hansen, E., Andersen, J. H., Svenson, J., Blinov, K., Repisky, M., Mohn, F., Meyer, G., Svendsen, J-S., Ruud, K., Elyashberg, M., Gross, L., Jaspars, M. & Isaksson, J., 3 Dec 2012, In : Angewandte Chemie International Edition. 51, 49, p. 12238-12241 4 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2017

A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize

Booth, J., Alexandru-Crivac, C-N., Rickaby, K. A., Nneoyiegbe, A. F., Umeobika, U., McEwan, A. R., Trembleau, L., Jaspars, M., Houssen, W. E. & Shalashilin, D. V., 18 May 2017, In : The Journal of Physical Chemistry Letters. 8, 10, p. 2310-2315 6 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
12 Downloads (Pure)
2014

Mitigation of ROS Insults by Streptomyces Secondary Metabolites in Primary Cortical Neurons

Leirós, M., Alonso, E., Sanchez, J. A., Rateb, M. E. M., Ebel, R., Houssen, W. E., Jaspars, M., Alfonso, A. & Botana, L. M., 15 Jan 2014, In : ACS Chemical Neuroscience. 5, 1, p. 71-80 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2019

LC-HRMS-Database Screening Metrics for Rapid Prioritization of Samples to Accelerate the Discovery of Structurally New Natural Products

Tabudravu, J. N., Pellissier, L., Smith, A. J., Subko, K., Autréau, C., Feussner, K., Hardy, D., Butler, D., Kidd, R., Milton, E. J., Deng, H., Ebel, R., Salonna, M., Gissi, C., Montesanto, F., Kelly, S. M., Milne, B. F., Cimpan, G. & Jaspars, M., 2019, In : Journal of Natural Products. 82, 2, p. 211-220 10 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
2 Downloads (Pure)
2011

Synoxazolidinone C; A bicyclic member of the synoxazolidinone family with antibacterial and anticancer activities

Tadesse, M., Svenson, J., Jaspars, M., Strøm, M. B., Abdelrahman, M. H., Andersen, J. H., Hansen, E., Kristiansen, P. E., Stensvg, K. & Haug, T., 13 Apr 2011, In : Tetrahedron Letters. 52, 15, p. 1804-1806 3 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2020

Downsizing Class II Lasso Peptides: Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle

Cortés-Albayay, C., Jarmusch, S. A., Trusch, F., Ebel, R., Andrews, B. A., Jaspars, M. & Asenjo, J. A., 7 Feb 2020, In : Journal of Organic Chemistry. 85, 3, p. 1661-1667 7 p.

Research output: Contribution to journalArticle

2012

Antimicrobial antioxidant daucane sesquiterpenes from Ferula hermonis Boiss

Ibraheim, Z. Z., Abdel-Mageed, W. M., Dai, H., Guo, H., Zhang, L. & Jaspars, M., Apr 2012, In : Phytotherapy Research. 26, 4, p. 579-586 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2017

Cyclic Peptides – A Look to the Future

Idress, M., Alexandru-Crivac, C. N., Jaspars, M., Trembleau, L. A. C., Houssen Ibrahim, W. E-S. M., Rickaby, K. A. & Dalponte, L., 15 Dec 2017, Cyclic Peptides: From Bioorganic Synthesis to Applications . Koehnke, J., Naismith, J. & van der Donk, W. A. (eds.). UK: Royal Society of Chemistry (Great Britain) , p. 340-373 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Antibiotics from Deep-Sea Microorganisms: Current Discoveries and Perspectives

Tortorella, E., Tedesco, P., Palma Esposito, F., January, G. G., Fani, R., Jaspars, M. & de Pascale, D., 29 Sep 2018, In : Marine Drugs. 16, 10, 16 p., 355.

Research output: Contribution to journalReview article

Open Access
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22 Citations (Scopus)
9 Downloads (Pure)
2015

Biosynthesis of neocarazostatin A reveals the sequential carbazole prenylation and hydroxylation in the tailoring steps

Huang, S., Elsayed, S. S., Lv, M., Tabudravu, J., Rateb, M. E., Gyampoh, R., Kyeremeh, K., Ebel, R., Jaspars, M., Deng, Z., Yu, Y. & Deng, H., 17 Dec 2015, In : Chemistry & Biology. 22, 12, p. 1633-1642 10 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
10 Downloads (Pure)

Diversity of organic structures of marine microbial origin with drug potential

Jaspars, M., Ebel, R. P. & Deng, H., 2015, Phycotoxins: Chemistry and Biochemistry. Botana, LM. & Alfonso, A. (eds.). 2 ed. Blackwell Science, p. 361-380 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)
2017

Targeted Dereplication of Microbial Natural Products by High-Resolution MS and Predicted LC Retention Time

Chervin, J., Stierhof, M., Tong, M. H., Peace, D., Hansen, K. Ø., Urgast, D. S., Andersen, J. H., Yu, Y., Ebel, R., Kyeremeh, K., Paget, V., Cimpan, G., Wyk, A. V., Deng, H., Jaspars, M. & Tabudravu, J. N., 26 May 2017, In : Journal of Natural Products. 80, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

Open Access
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16 Citations (Scopus)
5 Downloads (Pure)
2016

Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD

Bent, A. F., Mann, G., Houssen, W. E., Mykhaylyk, V., Duman, R., Thomas, L., Jaspars, M., Wagner, A. & Naismith, J. H., 1 Nov 2016, In : Acta Crystallographica Section D: Structural Biology. 72, 11, p. 1174-1180 7 p.

Research output: Contribution to journalArticle

Open Access
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10 Citations (Scopus)
8 Downloads (Pure)
2014

The origins of cyanobactin chemistry and biology

Jaspars, M., 14 Sep 2014, In : Chemical Communications. 50, 71, p. 10174-10176 3 p.

Research output: Contribution to journalEditorial

9 Citations (Scopus)
2019

Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae

Martínez, K. A., Lauritano, C., Druka, D., Romano, G., Grohmann, T., Jaspars, M., Martín, J., Díaz, C., Cautain, B., de la Cruz, M., Ianora, A. & Reyes, F., 27 Jun 2019, In : Marine Drugs. 17, 7, 385.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
4 Downloads (Pure)
2016

Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics

Oueis, E., Jaspars, M., Westwood, N. J. & Naismith, J. H., 4 May 2016, In : Angewandte Chemie International Edition. 55, 19, p. 5842-5845 4 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
8 Downloads (Pure)
2015

Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert

Elsayed, S. S., Trusch, F., Deng, H., Raab, A., Prokes, I., Busarakam, K., Asenjo, J. A., Andrews, B. A., van West, P., Bull, A. T., Goodfellow, M., Yi, Y., Ebel, R., Jaspars, M. & Rateb, M. E., 2015, In : Journal of Organic Chemistry. 80, 20, p. 10252-10260 9 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2019

Legonoxamines A-B, two new hydroxamate siderophores from the soil bacterium, Streptomyces sp. MA37

Maglangit, F., Tong, M. H., Jaspars, M., Kyeremeh, K. & Deng, H., 3 Jan 2019, In : Tetrahedron Letters. 60, 1, p. 75-79 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

Houssen, W. E., Bent, A. F., McEwan, A. R., Pieiller, N., Tabudravu, J., Koehnke, J., Mann, G., Adaba, R. I., Thomas, L., Hawas, U. W., Liu, H., Schwarz-Linek, U., Smith, M. C. M., Naismith, J. H. & Jaspars, M., 15 Dec 2014, In : Angewandte Chemie International Edition. 53, 51, p. 14171-14174 4 p.

Research output: Contribution to journalArticle

Open Access
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34 Citations (Scopus)
5 Downloads (Pure)
2013

Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

Arnison, P. G., Bibb, M. J., Bierbaum, G., Bowers, A. A., Bugni, T. S., Bulaj, G., Camarero, J. A., Campopiano, D. J., Challis, G. L., Clardy, J., Cotter, P. D., Craik, D. J., Dawson, M., Dittmann, E., Donadio, S., Dorrestein, P. C., Entian, K-D., Fischbach, M. A., Garavelli, J. S., Göransson, U. & 45 others, Gruber, C. W., Haft, D. H., Hemscheidt, T. K., Hertweck, C., Hill, C., Horswill, A. R., Jaspars, M., Kelly, W. L., Klinman, J. P., Kuipers, O. P., Link, A. J., Liu, W., Marahiel, M. A., Mitchell, D. A., Moll, G. N., Moore, B. S., Müller, R., Nair, S. K., Nes, I. F., Norris, G. E., Olivera, B. M., Onaka, H., Patchett, M. L., Piel, J., Reaney, M. J. T., Rebuffat, S., Ross, R. P., Sahl, H-G., Schmidt, E. W., Selsted, M. E., Severinov, K., Shen, B., Sivonen, K., Smith, L., Stein, T., Süssmuth, R. D., Tagg, J. R., Tang, G-L., Truman, A. W., Vederas, J. C., Walsh, C. T., Walton, J. D., Wenzel, S. C., Willey, J. M. & van der Donk, W. A., Jan 2013, In : Natural Product Reports. 30, 1, p. 108-160 53 p.

Research output: Contribution to journalArticle

866 Citations (Scopus)
2015

Aspiperidine oxide, a piperidine N-oxide from the filamentous fungus Aspergillus indologenus

Petersen, L. M., Kildgaard, S., Jaspars, M. & Larsen, T. O., 1 Apr 2015, In : Tetrahedron Letters. 56, 14, p. 1847-1850 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Natural product diversity of actinobacteria in the Atacama Desert

Rateb, M. E., Ebel, R. & Jaspars, M., Aug 2018, In : Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology. 111, 8, p. 1467-1477 11 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
8 Downloads (Pure)
2012
2 Citations (Scopus)
2018

Mare Geneticum: Balancing Governance of Marine Genetic Resources in International Waters

Broggiato, A., Vanagt, T., Lallier, L. E., Jaspars, M., Burton, G. & Muyldermans, D., Mar 2018, In : International Journal of Marine and Coastal Law. 33, 1, p. 3-33 31 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
17 Downloads (Pure)
2016

A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

Parajuli, A., Kwak, D. H., Dalponte, L., Leikoski, N., Galica, T., Umeobika, U., Trembleau, L., Bent, A., Sivonen, K., Wahlsten, M., Wang, H., Rizzi, E., De Bellis, G., Naismith, J., Jaspars, M., Liu, X., Houssen, W. & Fewer, D. P., 7 Mar 2016, In : Angewandte Chemie. 128, 11, p. 3660-3663 4 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
9 Downloads (Pure)
2014

Almiramide D, cytotoxic peptide from the marine cyanobacterium Oscillatoria nigroviridis

Quintana, J., Bayona, L. M., Castellanos, L., Puyana, M., Camargo, P., Aristizábal, F., Edwards, C., Tabudravu, J. N., Jaspars, M. & Ramos, F. A., 15 Dec 2014, In : Bioorganic & Medicinal Chemistry. 22, 24, p. 6789-6795 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2019

Heterologous expression of a cryptic gene cluster from Streptomyces leeuwenhoekii C34T yields a novel lasso peptide, leepeptin

Gomez-Escribano, J. P., Castro, J. F., Razmilic, V., Jarmusch, S. A., Saalbach, G., Ebel, R., Jaspars, M., Andrews, B., Asenjo, J. A. & Bibb, M. J., 1 Dec 2019, In : Applied and Environmental Microbiology. 85, 23, 13 p., e01752-19.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
2 Downloads (Pure)
2014

Microbiology: a talented genus

Jaspars, M. & Challis, G. L., 6 Feb 2014, In : Nature. 506, 7486, p. 38-39 2 p.

Research output: Contribution to journalComment/debate

11 Citations (Scopus)
2015

Polymeric alkylpyridinium salts permit intracellular delivery of human Tau in rat hippocampal neurons: requirement of Tau phosphorylation for functional deficits

Koss, D. J., Robinson, L., Mietelska-Porowska, A., Gasiorowska, A., Sepcic, K., Turk, T., Jaspars, M., Niewiadomska, G., Scott, R. H., Platt, B. & Riedel, G., Dec 2015, In : Cellular and Molecular Life Sciences. 72, 23, p. 4613-4632 20 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2013

Structure of PatF from Prochloron didemni

Bent, A. F., Koehnke, J., Houssen, W. E., Smith, M. C. M., Jaspars, M. & Naismith, J. H., Jun 2013, In : Acta Crystallographica Section F: Structural Biology Communications . 69, 6, p. 618-623 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2017

Increased Biological Activity of Aneurinibacillus migulanus Strains Correlates with the Production of New Gramicidin Secondary Metabolites

Alenezi, F. N., Rekik, I., Bouket, A. C., Luptakova, L., Rateb, M. E., Weitz, H., Jaspars, M., Woodward, S. & Belbahri, L., 7 Apr 2017, In : Frontiers in Microbiology. 8, p. 1-11 11 p., 517.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
6 Downloads (Pure)
2014

Citrinadin A derivatives from Penicillium citrinum, an endophyte from the marine red alga Dichotomaria marginata

de JASAndrade, T., Somensi, A., Lopes, M. N., Araujo, A. R., Jaspars, M. & Silva, D. H. S., Jul 2014, In : Planta Medica. 80, 10, p. 776 1 p., PC37.

Research output: Contribution to journalAbstract

2012

Contemporary strategies in natural products structure elucidation

Rodríguez, J., Crews, P. & Jaspars, M., 2012, Handbook of Marine Natural Products. Springer Netherlands, p. 423-517 95 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)
2016

New cytotoxic callipeltins from the Solomon Island marine sponge Asteropus sp.

Stierhof, M., Hansen, K. Ø., Sharma, M., Feussner, K., Subko, K., Díaz-Rullo, F. F., Isaksson, J., Pérez-Victoria, I., Clarke, D., Hansen, E., Jaspars, M. & Tabudravu, J. N., 3 Nov 2016, In : Tetrahedron. 72, 44, p. 6929-6934 6 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
7 Downloads (Pure)
2013

Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus

Wang, X., Tabudravu, J., Rateb, M., Annand, K. J., Qin, Z., Jaspars, M., Deng, Z., Yu, Y. & Deng, H., Jun 2013, In : Molecular BioSystems. 9, 6, p. 1286-1289 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2014

Isolation and Synthesis of Pulmonarins A and B, Acetylcholinesterase Inhibitors from the Colonial Ascidian Synoicum pulmonaria

Tadesse, M., Svenson, J., Sepicic, K., Trembleau, L., Engqvist, M., Andersen, J. H., Jaspars, M., Stensvag, K. & Haug, T., 28 Feb 2014, In : Journal of Natural Products. 77, 2, p. 364-369 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2016

Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation

Sánchez, J. A., Alfonso, A., Rodriguez, I., Alonso, E., Cifuentes, J. M., Bermudez, R., Rateb, M. E., Jaspars, M., Houssen, W. E., Ebel, R., Tabudravu, J. & Botana, L. M., 24 Oct 2016, In : Frontiers in Immunology. 7, 452.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
6 Downloads (Pure)
2013

Nivetetracyclates A and B: Novel Compounds Isolated from Streptomyces niveus

Chen, C., Liu, X., Abdel-Mageed, W. M., Guo, H., Hou, W., Jaspars, M., Li, L., Xie, F., Ren, B., Wang, Q., Dai, H., Song, F. & Zhang, L., 15 Nov 2013, In : Organic Letters. 15, 22, p. 5762-5765 4 p.

Research output: Contribution to journalLetter

6 Citations (Scopus)
2018

Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A2 and Azaspirofuran A

Copmans, D., Rateb, M., Tabudravu, J. N., Pérez-Bonilla, M., Dirkx, N., Vallorani, R., Diaz, C., Pérez Del Palacio, J., Smith, A. J., Ebel, R., Reyes, F., Jaspars, M. & de Witte, P. A. M., 2018, In : ACS Chemical Neuroscience. 9, 7, p. 1652-1662 11 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
5 Downloads (Pure)
2020

A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

2013

Tianchimycins A-B, 16-membered macrolides from the rare actinomycete Saccharothrix xinjiangensis

Wang, X., Tabudravu, J., Jaspars, M. & Deng, H., 29 Jul 2013, In : Tetrahedron. 69, 30, p. 6060-6064 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2015

Commiphora gileadensis sap extract induces cell cycle-dependent death in immortalized keratinocytes and human dermoid carcinoma

Wineman, E., Douglas, I., Wineman, V., Sharova, K., Jaspars, M., Meshner, S., Bentwich, Z., Cohen, G. & Shtevi, A., Dec 2015, In : Journal of herbal medicine. 5, 4, p. 199-206 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
5 Downloads (Pure)

Discovery of a single monooxygenase catalyzing the carbamate formation and ring contraction in the biosynthesis of legonmycins

Huang, S., Tabudravu, J., Elsayed, S. S., Travert, J., Peace, D., Tong, M. H., Kyeremeh, K., Kelly, S., Trembleau, L. A. C., Ebel, R. P., Jaspars, M., Yu, Y. & Deng, H., 19 Oct 2015, In : Angewandte Chemie International Edition. 54, 43, p. 12697-12701 4 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
6 Downloads (Pure)
2017

Bypassing the proline/thiazoline requirement of the macrocyclase PatG

Oueis, E., Stevenson, H., Jaspars, M., Westwood, N. J. & Naismith, J. H., 25 Nov 2017, In : Chemical Communications. 53, 91, p. 12274-12277 4 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
5 Downloads (Pure)
2012

Antifungal and antibacterial activity of 3-alkylpyridinium polymeric analogs of marine toxins

Zovko, A., Gabric, M. V., Sepcic, K., Pohleven, F., Jaklic, D., Gunde-Cimerman, N., Lu, Z., Edrada-Ebel, R., Houssen, W. E., Mancini, I., Defant, A., Jaspars, M. & Turk, T., Mar 2012, In : International Biodeterioration & Biodegradation. 68, p. 71-77 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2011

Cutting the cost of HP/HT cleanups: Novel high density cleanup package enables brine reclamation and reduces costs

Richmond, M., Hutton, A., Davidson, M., Howard, S., Frost, B., Leon, S. & Jaspars, M., 13 Jun 2011, Society of Petroleum Engineers - SPE/IADC Drilling Conference and Exhibition 2011. Vol. 2. p. 752-757 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)
2013

The fish pathogen Yersinia ruckeri produces holomycin and uses an RNA methyltransferase for self-resistance

Qin, Z., Baker, A. T., Raab, A., Huang, S., Wang, T., Yu, Y., Jaspars, M., Secombes, C. J. & Deng, H., 24 May 2013, In : The Journal of Biological Chemistry. 288, 21, p. 14688-14697 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2 Downloads (Pure)
2020

A tiered approach to the marine genetic resource governance framework under the proposed UNCLOS agreement for biodiversity beyond national jurisdiction (BBNJ)

Humphries, F., Gottlieb, H. M., Laird, S., Wynberg, R., Lawson, C., Rourke, M., Tvedt, M. W., Oliva, M. J. & Jaspars, M., 9 Mar 2020, In : Marine Policy. 14 p., 103910.

Research output: Contribution to journalArticle

Open Access
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1 Downloads (Pure)
2016

Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross Sea (Antarctica)

Tedesco, P., Maida, I., Palma Esposito, F., Tortorella, E., Subko, K., Ezeofor, C. C., Zhang, Y., Tabudravu, J., Jaspars, M., Fani, R. & de Pascale, D., 26 Apr 2016, In : Marine Drugs. 14, 5, p. 1-14 14 p., 83.

Research output: Contribution to journalArticle

Open Access
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24 Citations (Scopus)
8 Downloads (Pure)