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Author

  • Neil Vargesson
2013

Reply to D’Amato et al. and Zeldis et al. Screening of thalidomide derivatives in chicken and zebrafish embryos

Vargesson, N., Mahony, C., Erskine, L., Niven, J., Greig, N. H. & Figg, W. D., 10 Dec 2013, In : PNAS. 110, 50, E4820.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

The chick limb: embryology, genetics and teratology

Davey, M. G., Towers, M., Vargesson, N. & Tickle, C., 19 Mar 2018, In : International Journal of Developmental Biology. 62, p. 85-95 11 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
6 Downloads (Pure)
2011

Thalidomide

Vargesson, N., Mar 2011, Reproductive and Developmental Toxicology. Gupta, R. (ed.). Elsevier Science , p. 395-403 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

Roles of Roundabout and Slits in developing limb joint formation

Diamond, A., Erskine, L. & Vargesson, N., Apr 2015, In : International journal of experimental pathology. 96, 2, p. A8-A8 1 p.

Research output: Contribution to journalAbstract

2017

Thalidomide

Vargesson, N., 21 Apr 2017, Reproductive and Developmental Toxicology . Gupta, R. C. (ed.). 2nd ed. Academic Press, p. 467-479 13 p. Chapter 26

Research output: Chapter in Book/Report/Conference proceedingChapter

'The Legacy of Thalidomide' - a multidisciplinary Meeting held at the University of York, UK on September 30, 2016

Newbronner, E., Vargesson, N. & Atkin, K., 1 Mar 2017, In : Birth Defects Research. 109, 4, p. 296–299 4 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
5 Downloads (Pure)
2016

Quantitative assessment of intrinsic noise for visually guided behaviour in zebrafish

Spilioti, M., Vargesson, N. & Neri, P., Oct 2016, In : Vision Research. 127, p. 104-114 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
5 Downloads (Pure)
2017

Developmental Angiogenesis

Vargesson, N., Jun 2017, In : Reproductive Toxicology. 70, p. 1-2 2 p.

Research output: Contribution to journalEditorial

2011

Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis

Lindström, N. O., Neves, C., McIntosh, R., Miedzybrodzka, Z. H., Vargesson, N. & Collinson, J. M., Mar 2011, In : Gene Expression Patterns. 11, 3-4, p. 221-232 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2018

Design, synthesis and biological assessment of N-adamantyl, substituted adamantyl and noradamantyl phthalimidines for nitrite, TNF-α and angiogenesis inhibitory activities

Luo, W., Tweedie, D., Beedie, S-L., Vargesson, N., Figg, W. D., Greig, N. H. & Scerba, M. T., 1 May 2018, In : Bioorganic & Medicinal Chemistry. 26, 8, p. 1547-1559 13 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
7 Downloads (Pure)
2020

Role of cereblon in angiogenesis and in mediating the antiangiogenic activity of immunomodulatory drugs

Beedie, S. L., Huang, P. A., Harris, E. M., Strope, J. D., Mahony, C., Chau, C. H., Vargesson, N. & Figg, W. D., 1 Sep 2020, In : The FASEB Journal. 34, 9, p. 11395-11404 10 p.

Research output: Contribution to journalArticle

Open Access
2019

VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle

Figeac, N., Mohamed, A. D., Sun, C., Schönfelder, M., Matallanas, D., Garcia-Munoz, A., Missiaglia, E., Collie-Duguid, E., De Mello, V., Pobbati, A. V., Pruller, J., Jaka, O., Harridge, S. D. R., Hong, W., Shipley, J., Vargesson, N., Zammit, P. S. & Wackerhage, H., 5 Jul 2019, In : Journal of Cell Science. 132, jcs225946 .

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
5 Downloads (Pure)

Vgll3 interacts with Yap/Taz-Tead1-4-dependent gene expression in skeletal muscle

Figeac, N., Mohamed, A. A. D., Sun, C., Schonfelder, M., Gomez, D., Garcia-Munoz, A., Missiaglia, E., Collie-Duguid, E., De Mello, V., Pobbati, A. V., Jaka, O., Harridge, S. D. R., Hong, W., Shipley, J., Vargesson, N., Zammit, P. S. & Wackerhage, H., Mar 2019, In : European Journal of Translational Myology. 29, 1, p. 53-53 1 p.

Research output: Contribution to journalAbstract

Open Access
File
14 Downloads (Pure)
2018

Limbal epithelial stem cell activity and corneal epithelial cell cycle parameters in adult and aging mice

Sagga, N., Kuffova, L., Vargesson, N., Erskine, L. & Collinson, J. M., Dec 2018, In : Stem Cell Research. 33, 12, p. 185-198 14 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
6 Downloads (Pure)
2020

Genetic association and characterization of FSTL5 in isolated clubfoot

Khanshour, A. M., Kidane, Y., Kozlitina, J., Cornelia, R., Rafipay, A., De Mello, V., Weston, M., Paria, N., Khalid, A., Hecht, J. T., Dobbs, M. B., Richards, B. S., Vargesson, N., Kent Hamra, F., Wilson, M., Wise, C., Gurnett, C. A. & Rios, J. J., 14 Oct 2020, (Accepted/In press) In : Human Molecular Genetics.

Research output: Contribution to journalArticle

2018

The developmental and genetic basis of ‘clubfoot’ in the peroneal muscular atrophy mutant mouse

Collinson, J. M., Lindstrom, N. O., Neves, C., Wallace, K., Meharg, C., Charles, R., Fraser, A., Mbogo, I., Oras, K., Nakamoto, M., Barker, S., Duce, S., Miedzybrodzka, Z. & Vargesson, N., 8 Feb 2018, In : Development. 145, 3, dev160093.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
17 Downloads (Pure)
2017

Embryos, teratogens and birth defects

Vargesson, N., Sep 2017, In : Journal of Anatomy. 231, 3, p. 449 1 p.

Research output: Contribution to journalAbstract

2013

Molecular analysis of regulative events in the developing chick limb

Mahony, C. & Vargesson, N., 1 Jul 2013, In : Journal of Anatomy. 223, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2011

The NOTCH Pathway Contributes To Cell Fate Decision In Myelopoiesis

Bugeon, L., Taylor, H., Progatzky, F., Lin, M., Ellis, C., Welsh, N., Smith, E., Vargesson, N., Gray, C., Renshaw, S., Chico, T., Zon, L., Lamb, J. & Dallman, MJ., Dec 2011, In : Haematologica. 96, 12, p. 1753-1760 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2015
2019

The teratogenic effects of thalidomide on limbs

Vargesson, N., 1 Jan 2019, In : Journal of hand surgery-European volume. 44, 1, p. 88-95 8 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
11 Downloads (Pure)
2015

Thalidomide-induced Teratogenesis: History and Mechanisms

Vargesson, N., Jun 2015, In : Birth Defects Research. Part C, Embryo Today: Reviews. 105, 2, p. 140-156 17 p.

Research output: Contribution to journalArticle

Open Access
File
250 Citations (Scopus)
15 Downloads (Pure)
2018

CPS49-induced neurotoxicity does not cause limb patterning anomalies in developing chicken embryos

Mahony, C., McMenemy, S., Rafipay, A. J., Beedie, S-L., Rosa Fraga, L., Gutschow, M., Figg, W. D., Erskine, L. & Vargesson, N., 1 Mar 2018, In : Journal of Anatomy. 232, 4, p. 568-574 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
6 Downloads (Pure)
2017

Regarding a limb with PFFD, fibular dimelia and mirror foot deformity

Hootnick, D. R., Vargesson, N. & Birch, J., 1 Nov 2017, In : Journal of Pediatric Orthopaedics B. 26, 6, p. 589-589 1 p.

Research output: Contribution to journalLetter

Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function

Sun, C., De Mello, V., Mohamed, A., Quiroga, H. P. O., Garcia-Munoz, A., Al Bloshi, A., Tremblay, A. M., von Kriegsheim, A., Collie-Duguid, E., Vargesson, N., Matallanas, D., Wackerhage, H. & Zammit, P. S., Aug 2017, In : Stem Cells. 35, 8, p. 1958-1972 15 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
11 Downloads (Pure)
2016

Congenital Embryonic Arterial and Skeletal Dysgeneses

Hootnick, D. R., DeSesso, J. & Vargesson, N., Jul 2016, In : RadioGraphics. 36, 4, p. 1257-1257 1 p.

Research output: Contribution to journalLetter

Thalidomide and birth defects

Fraga, L., Diamond, A. & Vargesson, N., 2016, In : eLS. January 2016, p. 1-11 11 p., a0026052.

Research output: Contribution to journalArticle

Open Access
File
7 Downloads (Pure)

In Vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems

Beedie, S. L., Rore, H. M., Barnett, S., Chau, C. H., Luo, W., Greig, N. H., Figg, W. D. & Vargesson, N., 22 Apr 2016, In : Oncotarget. 7, 22, p. 33237-33245 9 p.

Research output: Contribution to journalArticle

Open Access
File
24 Citations (Scopus)
5 Downloads (Pure)
2018

The Primodos components Noretheristerone acetate and Ethinyl estradiol induce developmental abnormalities in zebrafish embryos

Brown, S., Rosa Fraga, L., Cameron, G., Erskine, L. & Vargesson, N., 13 Feb 2018, In : Scientific Reports. 8, 2917.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
8 Downloads (Pure)
2017

A new mammalian model system for thalidomide teratogenesis: Monodelphis domestica

Sorensen, D., Sackett, A., Urban, D. J., Maier, J., Vargesson, N. & Sears, K. E., Jun 2017, In : Reproductive Toxicology. 70, p. 126-132 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
6 Downloads (Pure)
2019

Vascular anomalies of the upper limb

Mende, K., Vargesson, N. & Sivakumar, B., 1 Mar 2019, In : Journal of hand surgery-European volume. 44, 3, p. 233-241 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
2 Downloads (Pure)
2017

VEGF-A and Neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels

Erskine, L., Francois, U., Denti, L., Joyce, A., Tillo, M., Bruce, F., Vargesson, N. & Ruhrberg, C., Jul 2017, In : Development. 144, 13, p. 2504-2516 13 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
8 Downloads (Pure)
2020

Positional Information – a concept underpinning our understanding of developmental biology

Vargesson, N., 1 Mar 2020, In : Developmental Dynamics. 249, 3, p. 298-312 15 p.

Research output: Contribution to journalArticle

Open Access
File
2016

Shared mechanism of teratogenicity of anti-angiogenic drugs identified in the chicken embryo model

Beedie, S. L., Mahony, C., Walker, H. M., Chau, C. H., Figg, W. D. & Vargesson, N., 22 Jul 2016, In : Scientific Reports. 6, p. 1-10 10 p., 30038.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
6 Downloads (Pure)
2013

Thalidomide embryopathy: an enigmatic challenge

Vargesson, N., 2013, In : ISRN Developmental Biology. 2013, 18 p., 241016.

Research output: Contribution to journalLiterature review

Open Access
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10 Downloads (Pure)
2017

Vertebrate embryos as tools for anti-angiogenic drug screening and function

Beedie, S., Diamond, A. J., Rosa Fraga, L., Figg, W. D. & Vargesson, N., 1 Jun 2017, In : Reproductive Toxicology. 70, p. 49-59 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
24 Downloads (Pure)
2018

Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma

Mohamed, A. D., Shah, N., Hettmer, S., Vargesson, N. & Wackerhage, H., 23 Oct 2018, In : Scientific Reports. 8, 10 p., 15674.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
9 Downloads (Pure)

Lens-regulated retinoic acid signalling controls expansion of the developing eye

Smith, J. N., Walker, H. M., Thompson, H., Collinson, J. M., Vargesson, N. & Erskine, L., 10 Oct 2018, In : Development. 145, 19, dev167171.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
3 Downloads (Pure)
2017

Teratogenesis

Vargesson, N. & Fraga, L., 15 Dec 2017, In : eLS. p. 1-7 7 p., a0026056.

Research output: Contribution to journalArticle

2018

Expression analysis of limb element markers during mouse embryonic development

Rafipay, A., Berg, A. L. R., Erskine, L. & Vargesson, N., 20 Nov 2018, In : Developmental Dynamics. 247, 11, p. 1217-1226 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
7 Downloads (Pure)
2013

Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro

Mahony, C., Erskine, L., Niven, J., Greig, N. H., Figg, W. D. & Vargesson, N., 30 Jul 2013, In : PNAS. 110, 31, p. 12703-12708 6 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2015

Anticancer Properties of a Novel Class of Tetrafluorinated Thalidomide Analogues

Beedie, S. L., Peer, C. J., Pisle, S., Gardner, E. R., Mahony, C., Barnett, S., Ambrozak, A., Gütschow, M., Chau, C. H., Vargesson, N. & Figg, W. D., Oct 2015, In : Molecular Cancer Therapeutics. 14, 10, p. 2228-2237 10 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
6 Downloads (Pure)
2017

Arterial dysgenesis and limb defects: Clinical and experimental examples

Vargesson, N. & Hootnick, D. R., 1 Jun 2017, In : Reproductive Toxicology. 70, p. 21-29 9 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
9 Downloads (Pure)
2018

The syndrome of proximal femur, fibula, and midline metatarsal long bone deficiencies

Hootnick, D. R. & Vargesson, N., 1 Sep 2018, In : Birth Defects Research. 110, 15, p. 1188-1193 6 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
2 Downloads (Pure)