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2020
Perspective: Quality Versus Quantity; Is It Important to Assess the Role of Enhancers in Complex Disease from an In Vivo Perspective?
McEwan, A. R. & MacKenzie, A., 23 Oct 2020, In: International Journal of Molecular Sciences. 21, 21, 12 p., 7856.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2017
A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize
Booth, J., Alexandru-Crivac, C-N., Rickaby, K. A., Nneoyiegbe, A. F., Umeobika, U., McEwan, A. R., Trembleau, L., Jaspars, M., Houssen, W. E. & Shalashilin, D. V., 18 May 2017, In: The Journal of Physical Chemistry Letters. 8, 10, p. 2310-2315 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)13 Downloads (Pure) -
2019
Disruption of an enhancer associated with addictive behaviour within the cannabinoid receptor-1 gene suggests a possible role in alcohol intake, cannabinoid response and anxiety-related behaviour
Hay, E. A., McEwan, A., Wilson, D., Barrett, P., D'Agostino, G., Pertwee, R. G. & MacKenzie, A., Nov 2019, In: Psychoneuroendocrinology. 109, p. 104407 8 p., 104407.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)5 Downloads (Pure) -
2020
CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake
McEwan, A. R., Davidson, C., Hay, E., Turnbull, Y., Erickson, J. C., Marini, P., Wilson, D., McIntosh, A., Adams, M. J., Murgatroyd, C., Barrett, P., Delibegovic, M., Clarke, T-K. & MacKenzie, A., 13 Mar 2020, In: Molecular Psychiatry.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)1 Downloads (Pure) -
2016
Accurate quantification of modified cyclic peptides without the need for authentic standards
Adaba, R. I., Mann, G., Raab, A., Houssen, W. E., McEwan, A. R., Thomas, L., Tabudravu, J., Naismith, J. H. & Jaspars, M., 29 Dec 2016, In: Tetrahedron. 72, 52, p. 8603-8609 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)8 Downloads (Pure) -
2020
Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics
Hay, E. A., Cowie, P., McEwan, A. R., Ross, R., Pertwee, R. G. & MacKenzie, A., Jan 2020, In: Human Mutation. 41, 1, p. 291-298 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet
McEwan, A., Erickson, J. C., Davidson, C., Heijkoop, J., Turnbull, Y., Delibegovic, M., Murgatroyd, C. & MacKenzie, A., 12 Dec 2020, In: Cellular and Molecular Life Sciences.Research output: Contribution to journal › Article › peer-review
Open Access -
2011
Zinc is essential for high-affinity DNA binding and recombinase activity of phi C31 integrase
McEwan, A. R., Raab, A., Kelly, S. M., Feldmann, J. & Smith, M. C. M., Aug 2011, In: Nucleic Acids Research. 39, 14, p. 6137-6147 11 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
2014
An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides
Houssen, W. E., Bent, A. F., McEwan, A. R., Pieiller, N., Tabudravu, J., Koehnke, J., Mann, G., Adaba, R. I., Thomas, L., Hawas, U. W., Liu, H., Schwarz-Linek, U., Smith, M. C. M., Naismith, J. H. & Jaspars, M., 15 Dec 2014, In: Angewandte Chemie International Edition. 53, 51, p. 14171-14174 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)6 Downloads (Pure) -
2017
Isolation and anti-HIV-1 integrase activity of lentzeosides A-F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil
Wichner, D., Idris, H., Houssen, W. E., McEwan, A. R., Bull, A. T., Asenjo, J. A., Goodfellow, M., Jaspars, M., Ebel, R. & Rateb, M. E., Apr 2017, In: The Journal of antibiotics. 70, p. 448-453 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)7 Downloads (Pure)