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• 2019

  Enzymatic radiosynthesis of a ¹⁸F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)

  Lowe, P. T., Dall'Angelo, S., Fleming, I. N., Piras, M., Zanda, M. & O'Hagan, D., 2019, In: Organic & Biomolecular Chemistry. 17, 6, p. 1480-1486 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • antigens
  • Prostate-Specific Antigen
  • ligands
  • Membranes
  • membranes
  4 Citations (Scopus)

  3 Downloads (Pure)
• 2020

  Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers

  Longo, B., Zanato, C., Piras, M., Dall'angelo, S., Windhorst, A. D., Vugts, D., Baldassarre, M. & Zanda, M., 16 Sep 2020, In: Bioconjugate Chemistry. 31, 9, p. 2201-2210 10 p.

  Research output: Contribution to journal › Article › peer-review

  • 1,5-cyclooctadiene
  • Cyclooctanes
  • Electrons
  • Cycloaddition Reaction
  • Carbonates
  1 Citation (Scopus)
• 2018

  Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status

  Andriu, A., Crockett, J., Dall'Angelo, S., Piras, M., Zanda, M. & Fleming, I. N., Feb 2018, In: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging. 20, 1, p. 27-36 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Integrins
  • Mitogen-Activated Protein Kinase Kinases
  • Talin
  • arginyl-glycyl-aspartic acid
  • Pharmacology
  10 Citations (Scopus)

  9 Downloads (Pure)
• 2016

  NGR Tumor-Homing Peptides: Structural Requirements for Effective APN (CD13) Targeting

  Graziadio, A., Zanda, M., Frau, S., Fleming, I. N., Musolino, M., Dall'Angelo, S., Baldassarre, M. & Piras, M., 18 May 2016, In: Bioconjugate Chemistry. 27, 5, p. 1332-1340 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cyclic Peptides
  • Peptides
  • Tumors
  • Cells
  • Neoplasms
  19 Citations (Scopus)

  7 Downloads (Pure)
• 2019

  The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs)

  Tseng, C-C., Baillie, G., Donvito, G., Mustafa, M. A., Juola, S. E., Zanato, C., Massarenti, C., Dall'angelo, S., Harrison, W. T. A., Lichtman, A. H., Ross, R. A., Zanda, M. & Greig, I. R., 2019, In: Journal of Medicinal Chemistry. 62, 10, p. 5049-5062 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • Cannabinoid Receptor CB1
  • nitromethane
  • Allosteric Site
  • Neuralgia
  • Pharmaceutical Preparations
  13 Citations (Scopus)

  4 Downloads (Pure)
• 2017

  Design, synthesis, in vitro characterization and preliminary imaging studies on fluorinated bile acid derivatives as PET tracers to study hepatic transporters

  Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A. E., Elmore, C. S., Sharma, P. & Zanda, M., 1 Feb 2017, In: Bioorganic & Medicinal Chemistry. 25, 3, p. 963-976 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • Positron emission tomography
  • Liver
  • Bile Acids and Salts
  • Positron-Emission Tomography
  • Derivatives
  11 Citations (Scopus)

  9 Downloads (Pure)
• 2018

  Enzymatic Fluorination of Biotin and Tetrazine Conjugates for Pretargeting Approaches to Positron Emission Tomography Imaging

  Lowe, P. T., Dall'angelo, S., Devine, A., Zanda, M. & O'Hagan, D., 17 Sep 2018, In: ChemBioChem. 19, 18, p. 1969-1978 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • fluorinase
  • Fluorination
  • Positron emission tomography
  • Halogenation
  • Polyethylene glycols
  7 Citations (Scopus)

  3 Downloads (Pure)
• 2017

  Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by (1)H NMR spectroscopy

  Fernandez Diaz-Rullo, F., Zamberlan, F., Mewis, R. E., Fekete, M., Broche, L., Cheyne, L. A., Dall'Angelo, S., Duckett, S. B., Dawson, D. & Zanda, M., 15 May 2017, In: Bioorganic & Medicinal Chemistry. 25, 10, p. 2730-2742 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • Nuclear magnetic resonance spectroscopy
  • Magnetic Resonance Spectroscopy
  • Nitric Oxide
  • Nuclear magnetic resonance
  • Substrates
  5 Citations (Scopus)

  7 Downloads (Pure)
• 2018

  Preclinical Evaluation of [¹⁸F]LCATD as a PET Tracer to Study Drug-Drug Interactions Caused by Inhibition of Hepatic Transporters

  Testa, A., Dall'Angelo, S., Mingarelli, M., Augello, A., Schweiger, L., Welch, A., Elmore, C. S., Dawson, D., Sharma, P. & Zanda, M., 30 Jul 2018, In: Contrast Media & Molecular Imaging. 2018, 10 p., 3064751.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Interactions
  • rifamycin SV
  • Liver
  • Pharmaceutical Preparations
  • Fusidic Acid
  10 Downloads (Pure)
• 2017

  High Affinity “Click” RGD Peptidomimetics as Radiolabeled Probes for Imaging αvβ3 Integrin

  Piras, M., Testa, A., Fleming, I. N., Dall'Angelo, S., Andriu, A., Menta, S., Mori, M., Brown, G. D., Forster, D., Williams, K. J. & Zanda, M., 20 Jul 2017, In: ChemMedChem. 12, 14, p. 1142-1151 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Peptidomimetics
  • Tumors
  • Integrins
  • Alkynes
  • Click Chemistry
  6 Citations (Scopus)

  11 Downloads (Pure)
• 2020

  Design, synthesis, radiosynthesis and biological evaluation of Fenretinide analogues as anticancer and metabolic syndromepreventive agents

  Zanda, M., Patruno, I., Thompson, D., Dall'angelo, S., Windhorst, A. D., Vugts, D. J., Poot, A. J. & Mody, N., 19 Aug 2020, In: ChemMedChem. 15, 16, p. 1579-1590 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fenretinide
  • Tretinoin
  • Cells
  • 3T3-L1 Cells
  • Pathology

• [18F]ZCDD083: a PFKFB3-targeted PET tracer for atherosclerotic plaque imaging

  De Dominicis, C., Perrotta, P., Dall'angelo, S., Wyffels, L., Staelens, S., de Meyer, G. R. Y. & Zanda, M., 14 May 2020, In: ACS Medicinal Chemistry Letters. 11, 5, p. 933-939 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Apolipoproteins E
  • Atherosclerotic Plaques
  • Imaging techniques
  • Arches
  • Autoradiography
  1 Citation (Scopus)

• Hypoxia PET/CT and Colorectal Cancer: A Case Report

  Laws, K., Murray, G. I., Kerr, K., McKiddie, F., Dall'angelo, S., Zanda, M., Fleming, I. & Samuel, L., 12 Aug 2020, In: Journal of Case Reports and Images in Oncology. 1(1), 2-5, 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Positron Emission Tomography Computed Tomography
  • Colorectal Neoplasms
  • Hypoxia
  • fluoroazomycin arabinoside
  • Carbonic Anhydrase IX
  1 Downloads (Pure)

• Widespread tissue hypoxia dysregulates cell and metabolic pathways in SMA

  Hernandez Gerez, E., Dall'angelo, S., Collinson, J. M., Fleming, I. N. & Parson, S. H., Sep 2020, In: Annals of Clinical and Translational Neurology. 7, 9, p. 1580-1593 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Spinal Muscular Atrophy
  • Cell Hypoxia
  • Metabolic Networks and Pathways
  • Motor Neurons
  • Hypoxia
• 2017

  Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers

  Zanato, C., Pelagalli, A., Marwick, K. F. M., Piras, M., Dall'Angelo, S., Spinaci, A., Pertwee, R. G., Wyllie, D. J. A., Hardingham, G. E. & Zanda, M., 2017, In: Organic & Biomolecular Chemistry. 15, 9, p. 2086-2096 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • HU 211
  • Radio
  • tracers
  • Derivatives
  • aspartates
  4 Citations (Scopus)

  9 Downloads (Pure)
• 2020

  A Weakened Immune Response to Synthetic Exo-Peptides Predicts a Potential Biosecurity Risk in the Retrieval of Exo-Microorganisms

  Schaefer, K., Dambuza, I. M., Dall'angelo, S., Trembleau, L., Zanda, M., Brown, G. D., Netea, M. G. & Gow, N. A. R., 17 Jul 2020, In: Microorganisms. 8, 7, 14 p., 1066.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • biosecurity
  • immune response
  • peptides
  • microorganisms
  • amino acids
  2 Downloads (Pure)
• 2016

  Last-step enzymatic [18F]-fluorination of cysteine-tethered RGD peptides using modified Barbas linkers

  Zhang, Q., Dall'Angelo, S., Fleming, I. N., Schweiger, L. F., Zanda, M. & O'Hagan, D., 25 Jul 2016, In: Chemistry : a European Journal. 22, 31, p. 10998-11004 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • fluorinase
  • Fluorination
  • arginyl-glycyl-aspartic acid
  • Peptides
  • Cysteine
  18 Citations (Scopus)

  7 Downloads (Pure)
• 2017

  Synthesis and radio-synthesis of prospective 2-nitroimidazole hypoxia PET tracers via thiazolidine ligation with 5-fluorodeoxyribose (FDR)

  Musolino, M., Dall'angelo, S. & Zanda, M., 2017, In: SynOpen. 1, 1, p. 173-179 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Thiazolidines
  • azomycin
  • Ribose
  • Sulfhydryl Compounds
  • Amines
  7 Downloads (Pure)
• 2020

  4,4,16-Trifluoropalmitate: design, synthesis, tritiation, radiofluorination and pre-clinical PET imaging studies on myocardial fatty acid oxidation

  Colombano, A., Dall'angelo, S., Kingston, L., Grönberg, G., Correia, C., Passannante, R., Baz, Z., Morcillo, M. A., Elmore, C., Llop, J. & Zanda, M., 3 Dec 2020, In: ChemMedChem. 15, 23, p. 2317-2331 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Positron emission tomography
  • Positron-Emission Tomography
  • Oxidation
  • Fatty Acids
  • Imaging techniques
• 2017

  A New Class of Fluorinated A_2A Adenosine Receptor Agonist with Application to Last-Step Enzymatic ¹⁸F Fluorination for PET Imaging

  Lowe, P. T., Dall'Angello, S., Mulder-Krieger, T., Ijzerman, A. P., Zanda, M. & O'Hagan, D., 2 Nov 2017, In: ChemBioChem. 18, 21, p. 2156-2164 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fluorination
  • Adenosine A2 Receptor Agonists
  • Positron emission tomography
  • Halogenation
  • 5'-fluoro-5'-deoxyadenosine
  9 Citations (Scopus)

  10 Downloads (Pure)

• Synthesis and Superpotent Anticancer Activity of Tubulysins Carrying Non-hydrolysable N-Substituents on Tubuvaline

  Sani, M., Lazzari, P., Folini, M., Spiga, M., Zuco, V., De Cesare, M., Manca, I., Dall'Angelo, S., Frigerio, M., Usai, I., Testa, A., Zaffaroni, N. & Zanda, M., 27 Apr 2017, In: Chemistry : a European Journal. 23, 24, p. 5842-5850 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vinorelbine
  • Paclitaxel
  • Cells
  • tubulysin A
  • Tubulin
  6 Citations (Scopus)

  9 Downloads (Pure)