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• 2015

  Gracilins: Spongionella-derived promising compounds for Alzheimer disease

  Leiros, M., Alonso, E., Rateb, M. E., Houssen, W. E., Ebel, R. P., Jaspars, M., Alfonso, A. & Botana, L. M., Jun 2015, In: Neuropharmacology. 93, p. 285-293 9 p.

  Research output: Contribution to journal › Article › peer-review
  39 Citations (Scopus)

• Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces Isolate

  Rateb, M. E., Zhai, Y., Ehrner, E., Rath, C., Wang, X., Tabudravu, J., Ebel, R. P., Bibb, M., Kyeremeh, K., Dorrestein, P., Hong, K., Jaspars, M. & Deng, H., 2015, In: Organic & Biomolecular Chemistry. 13, 37, p. 9585-9592 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • cypemycin
  • Streptomyces
  • dehydrobutyrine
  • Bioinformatics
  • Computational Biology
  21 Citations (Scopus)

  17 Downloads (Pure)

• Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert

  Elsayed, S. S., Trusch, F., Deng, H., Raab, A., Prokes, I., Busarakam, K., Asenjo, J. A., Andrews, B. A., van West, P., Bull, A. T., Goodfellow, M., Yi, Y., Ebel, R., Jaspars, M. & Rateb, M. E., 16 Oct 2015, In: Journal of Organic Chemistry. 80, 20, p. 10252-10260 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Genes
  • Peptides
  • Electrospray ionization
  • Biosynthesis
  • Mass spectrometry
  57 Citations (Scopus)

• Biosynthesis of Neocarazostatin A Reveals the Sequential Carbazole Prenylation and Hydroxylation in the Tailoring Steps

  Huang, S., Elsayed, S. S., Lv, M., Tabudravu, J., Rateb, M. E., Gyampoh, R., Kyeremeh, K., Ebel, R., Jaspars, M., Deng, Z., Yu, Y. & Deng, H., 17 Dec 2015, In: Chemistry & Biology. 22, 12, p. 1633-1642 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • neocarazostatin A
  • Hydroxylation
  • carbazole
  • Biosynthesis
  • Prenylation
  21 Citations (Scopus)

  11 Downloads (Pure)
• 2011

  Ophiobolin sesterterpenoids and pyrrolidine alkaloids from the sponge-derived fungus Aspergillus ustus

  Liu, H-B., Edrada-Ebel, R., Ebel, R., Wang, Y., Schulz, B., Draeger, S., Müller, W. E. G., Wray, V., Lin, W-H. & Proksch, P., Apr 2011, In: Helvetica Chimica Acta. 94, 4, p. 623-631 9 p.

  Research output: Contribution to journal › Article › peer-review

  • aurantiamine
  • cerebroside D
  • ophiobolins
  • Suberites
  • Alkaloids
  37 Citations (Scopus)
• 2016

  Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation

  Sánchez, J. A., Alfonso, A., Rodriguez, I., Alonso, E., Cifuentes, J. M., Bermudez, R., Rateb, M. E., Jaspars, M., Houssen, W. E., Ebel, R., Tabudravu, J. & Botana, L. M., 24 Oct 2016, In: Frontiers in Immunology. 7, 452.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cyclophilin A
  • gracilin L
  • Ear
  • Inflammation Mediators
  • T-Lymphocytes
  6 Citations (Scopus)

  7 Downloads (Pure)
• 2017

  Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation

  Wakefield, J., Hassan, H. M., Jaspars, M., Ebel, R. & Rateb, M. E., 11 Jul 2017, In: Frontiers in Microbiology. 8, p. 1-10 10 p., 1284.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Axenic Culture
  • pseurotin
  • Fermentation
  • terezine D
  • 11-O-methylpseurotin A
  50 Citations (Scopus)

  10 Downloads (Pure)
• 2016

  Identification of Spongionella compounds as cyclosporine A mimics

  Sánchez, J. A., Alfonso, A., Leirós, M., Alonso, E., Rateb, M. E., Jaspars, M., Houssen, W. E., Ebel, R., Tabudravu, J. & Botana, L. M., May 2016, In: Pharmacological Research. 107, p. 407-414 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cyclosporine
  • Cyclophilin A
  • Immunosuppressive Agents
  • 2-(4-acetoxyphenyl)-2-chloro-N-methylethylamine
  • calcineurin phosphatase
  9 Citations (Scopus)

  10 Downloads (Pure)
• 2015

  Bromoalkaloids Protect Primary Cortical Neurons from Induced Oxidative Stress

  Leiros, M., Alonso, E., Rateb, M. E., Houssen, W. E., Ebel, R., Jaspars, M., Alfonso, A. & Botana, L. M., Feb 2015, In: ACS Chemical Neuroscience. 6, 2, p. 331-338 8 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)
• 2013

  Induction of diverse secondary metabolites in Aspergillus fumigatus by microbial co-culture

  Rateb, M., Hallyburton, I., Houssen, W. E., Bull, A., Goodfellow, M., Santhanam, R., Jaspars, M. & Ebel, R., 5 Aug 2013, In: RSC Advances. 34, 3, p. 14444-14450 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Aspergillus
  • Metabolites
  • 11-O-methylpseurotin A
  • spirotryprostatin A
  • 6-methoxyspirotryprostatin B
  70 Citations (Scopus)

  7 Downloads (Pure)
• 2017

  Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040

  Sonnenschein, E. C., Stierhof, M., Goralczyk, S., Vabre, F. M., Pellissier, L., Hanssen, K. Ø., de la Cruz, M., Díaz, C., de Witte, P., Copmans, D., Andersen, J. H., Hansen, E., Kristoffersen, V., Tormo, J. R., Ebel, R., Milne, B. F., Deng, H., Gram, L., Jaspars, M. & Tabudravu, J. N., 4 May 2017, In: Tetrahedron. 73, 18, p. 2633-2637 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pseudoalteromonas
  • Siderophores
  • myxochelin B
  • myxochelin A
  • Cycloaddition
  9 Citations (Scopus)

  12 Downloads (Pure)

• Targeted Dereplication of Microbial Natural Products by High-Resolution MS and Predicted LC Retention Time

  Chervin, J., Stierhof, M., Tong, M. H., Peace, D., Hansen, K. Ø., Urgast, D. S., Andersen, J. H., Yu, Y., Ebel, R., Kyeremeh, K., Paget, V., Cimpan, G., Wyk, A. V., Deng, H., Jaspars, M. & Tabudravu, J. N., 26 May 2017, In: Journal of Natural Products. 80, 5, p. 1370-1377 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Biological Products
  • Streptomyces
  • Databases
  • Molecular mass
  • Molecular structure
  19 Citations (Scopus)

  6 Downloads (Pure)
• 2011

  Isolation, characterization, and bioactivity of endophytic fungi of Tylophora indica

  Kumar, S., Kaushik, N., Edrada-Ebel, R., Ebel, R. & Proksch, P., Mar 2011, In: World Journal of Microbiology and Biotechnology. 27, 3, p. 571-577 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Tylophora
  • Alternaria
  • Ascomycota
  • Fungi
  • Colletotrichum
  30 Citations (Scopus)
• 2012

  Pullularins E and F, two new peptides from the endophytic fungus Bionectria ochroleuca isolated from the mangrove plant Sonneratia caseolaris

  Ebrahim, W., Kjer, J., El Amrani, M., Wray, V., Lin, W., Ebel, R., Lai, D. & Proksch, P., 18 May 2012, In: Marine Drugs. 10, 5, p. 1081-1091 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Plant Leaves
  • Islands
  • Mass Spectrometry
  • Fungi
  • Magnetic Resonance Spectroscopy
  45 Citations (Scopus)

  7 Downloads (Pure)
• 2017

  Does Osmotic Stress Affect Natural Product Expression in Fungi?

  Overy, D., Correa, H., Roullier, C., Chi, W. C., Pang, K. L., Rateb, M., Ebel, R., Shang, Z., Capon, R., Bills, G. & Kerr, R., 13 Aug 2017, In: Marine Drugs. 15, 8, 254.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Osmotic Pressure
  • Biological Products
  • Osmolite
  • Fungi
  • Secondary Metabolism
  17 Citations (Scopus)

  7 Downloads (Pure)
• 2015

  Spongionella Secondary Metabolites Regulate Store Operated Calcium Entry Modulating Mitochondrial Functioning in SH-SY5Y Neuroblastoma Cells

  Andoni Sanchez, J., Alfonso, A., Leiros, M., Alonso, E., Rateb, M. E., Jaspars, M., Houssen, W. E., Ebel, R. P. & Botana, L. M., Sep 2015, In: Cellular Physiology and Biochemistry. 37, 2, p. 779-792 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  10 Citations (Scopus)

  5 Downloads (Pure)
• 2017

  Isolation and anti-HIV-1 integrase activity of lentzeosides A-F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil

  Wichner, D., Idris, H., Houssen, W. E., McEwan, A. R., Bull, A. T., Asenjo, J. A., Goodfellow, M., Jaspars, M., Ebel, R. & Rateb, M. E., Apr 2017, In: The Journal of antibiotics. 70, p. 448-453 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • HIV Integrase
  • p31 integrase protein, Human immunodeficiency virus 1
  • Glucosides
  • Actinobacteria
  • Glycosides
  17 Citations (Scopus)

  7 Downloads (Pure)
• 2013

  Comprehensive analysis of lipophilic arsenic species in a brown alga (Saccharina latissima)

  Raab, A., Newcombe, C., Pitton, D., Ebel, R. & Feldmann, J., 5 Mar 2013, In: Analytical Chemistry. 85, 5, p. 2817-2824 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Algae
  • Arsenic
  • Electrospray ionization
  • Fatty Acids
  • Phospholipids
  72 Citations (Scopus)
• 2015

  Discovery of a Single Monooxygenase that Catalyzes Carbamate Formation and Ring Contraction in the Biosynthesis of the Legonmycins

  Huang, S., Tabudravu, J., Elsayed, S. S., Travert, J., Peace, D., Tong, M. H., Kyeremeh, K., Kelly, S. M., Trembleau, L., Ebel, R., Jaspars, M., Yu, Y. & Deng, H., 19 Oct 2015, In: Angewandte Chemie International Edition. 54, 43, p. 12697-12701 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Alkaloids
  • Pyrrolizidine Alkaloids
  • Biosynthesis
  • Carbamates
  • Mixed Function Oxygenases
  23 Citations (Scopus)

  6 Downloads (Pure)

• Diversity of organic structures of marine microbial origin with drug potential

  Jaspars, M., Ebel, R. P. & Deng, H., 2015, Phycotoxins: Chemistry and Biochemistry. Botana, LM. & Alfonso, A. (eds.). 2 ed. Blackwell Science, p. 361-380 20 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  2 Citations (Scopus)
• 2011

  Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment

  Rateb, M. E., Houssen, W. E., Harrison, W. T. A., Deng, H., Okoro, C. K., Asenjo, J. A., Andrews, B. A., Bull, A. T., Goodfellow, M., Ebel, R. & Jaspars, M., 23 Sep 2011, In: Journal of Natural Products. 74, 9, p. 1965-1971 7 p.

  Research output: Contribution to journal › Article › peer-review
  88 Citations (Scopus)

• Chaxamycins A-D, Bioactive Ansamycins from a Hyper-arid Desert Streptomyces sp

  Rateb, M. E., Houssen, W. E., Arnold, M., Abdelrahman, M. H., Deng, H., Harrison, W. T. A., Okoro, C. K., Asenjo, J. A., Andrews, B. A., Ferguson, G., Bull, A. T., Goodfellow, M., Ebel, R. & Jaspars, M., Jun 2011, In: Journal of Natural Products. 74, 6, p. 1491-1499 9 p.

  Research output: Contribution to journal › Article › peer-review

  • chaxamycin A
  • Macrocyclic Lactams
  • HSP90 Heat-Shock Proteins
  • chaxamycin D
  • Streptomyces
  86 Citations (Scopus)