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  • Marcel Jaspars

A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize

Booth, J., Alexandru-Crivac, C-N., Rickaby, K. A., Nneoyiegbe, A. F., Umeobika, U., McEwan, A. R., Trembleau, L., Jaspars, M., Houssen, W. E. & Shalashilin, D. V., 18 May 2017, In : The Journal of Physical Chemistry Letters. 8, 10, p. 2310-2315 6 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
13 Downloads (Pure)

Access to and use of marine genetic resources: understanding the legal framework

Lallier, L. E., McMeel, O., Greiber, T., Vanagt, T., Dobson, A. D. W. & Jaspars, M., 2014, In : Natural Product Reports. 31, 5, p. 612-616 5 p.

Research output: Contribution to journalLiterature review

Open Access
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10 Citations (Scopus)
8 Downloads (Pure)

Accurate quantification of modified cyclic peptides without the need for authentic standards

Adaba, R. I., Mann, G., Raab, A., Houssen, W. E., McEwan, A. R., Thomas, L., Tabudravu, J., Naismith, J. H. & Jaspars, M., 29 Dec 2016, In : Tetrahedron. 72, 52, p. 8603-8609 7 p.

Research output: Contribution to journalArticle

Open Access
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3 Citations (Scopus)
8 Downloads (Pure)

A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

A combined atomic force microscopy and computational approach for the structural elucidation of Breitfussin A and B: highly modified halogenated dipeptides from Thuiaria breitfussi

Hanssen, K. O., Schuler, B., Williams, A. J., Demissie, T. B., Hansen, E., Andersen, J. H., Svenson, J., Blinov, K., Repisky, M., Mohn, F., Meyer, G., Svendsen, J-S., Ruud, K., Elyashberg, M., Gross, L., Jaspars, M. & Isaksson, J., 3 Dec 2012, In : Angewandte Chemie International Edition. 51, 49, p. 12238-12241 4 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

Almiramide D, cytotoxic peptide from the marine cyanobacterium Oscillatoria nigroviridis

Quintana, J., Bayona, L. M., Castellanos, L., Puyana, M., Camargo, P., Aristizábal, F., Edwards, C., Tabudravu, J. N., Jaspars, M. & Ramos, F. A., 15 Dec 2014, In : Bioorganic & Medicinal Chemistry. 22, 24, p. 6789-6795 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae

Martínez, K. A., Lauritano, C., Druka, D., Romano, G., Grohmann, T., Jaspars, M., Martín, J., Díaz, C., Cautain, B., de la Cruz, M., Ianora, A. & Reyes, F., 27 Jun 2019, In : Marine Drugs. 17, 7, 385.

Research output: Contribution to journalArticle

Open Access
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7 Citations (Scopus)
5 Downloads (Pure)

An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

Houssen, W. E., Bent, A. F., McEwan, A. R., Pieiller, N., Tabudravu, J., Koehnke, J., Mann, G., Adaba, R. I., Thomas, L., Hawas, U. W., Liu, H., Schwarz-Linek, U., Smith, M. C. M., Naismith, J. H. & Jaspars, M., 15 Dec 2014, In : Angewandte Chemie International Edition. 53, 51, p. 14171-14174 4 p.

Research output: Contribution to journalArticle

Open Access
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36 Citations (Scopus)
6 Downloads (Pure)

An enzymatic route to selenazolines

Koehnke, J., Morawitz, F., Bent, A. F., Houssen, W. E., Shirran, S. L., Fuszard, M. A., Smellie, I. A., Botting, C. H., Smith, M. C. M., Jaspars, M. & Naismith, J. H., 18 Mar 2013, In : ChemBioChem. 14, 5, p. 564-567 4 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Antibiotics from Deep-Sea Microorganisms: Current Discoveries and Perspectives

Tortorella, E., Tedesco, P., Palma Esposito, F., January, G. G., Fani, R., Jaspars, M. & de Pascale, D., 29 Sep 2018, In : Marine Drugs. 16, 10, 16 p., 355.

Research output: Contribution to journalReview article

Open Access
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24 Citations (Scopus)
10 Downloads (Pure)

Anticancer effects of bioactive berry compounds

Folmer, F., Basavaraju, U., Jaspars, M., Hold, G., El-Omar, E., Dicato, M. & Diederich, M., 1 Mar 2014, In : Phytochemistry reviews. 13, 1, p. 295-322 28 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Antifungal and antibacterial activity of 3-alkylpyridinium polymeric analogs of marine toxins

Zovko, A., Gabric, M. V., Sepcic, K., Pohleven, F., Jaklic, D., Gunde-Cimerman, N., Lu, Z., Edrada-Ebel, R., Houssen, W. E., Mancini, I., Defant, A., Jaspars, M. & Turk, T., Mar 2012, In : International Biodeterioration & Biodegradation. 68, p. 71-77 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross Sea (Antarctica)

Tedesco, P., Maida, I., Palma Esposito, F., Tortorella, E., Subko, K., Ezeofor, C. C., Zhang, Y., Tabudravu, J., Jaspars, M., Fani, R. & de Pascale, D., 26 Apr 2016, In : Marine Drugs. 14, 5, p. 1-14 14 p., 83.

Research output: Contribution to journalArticle

Open Access
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25 Citations (Scopus)
9 Downloads (Pure)

Antimicrobial antioxidant daucane sesquiterpenes from Ferula hermonis Boiss

Ibraheim, Z. Z., Abdel-Mageed, W. M., Dai, H., Guo, H., Zhang, L. & Jaspars, M., Apr 2012, In : Phytotherapy Research. 26, 4, p. 579-586 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Antiparasitic activity of bromotyrosine alkaloids and new analogues isolated from the Fijian marine Sponge Aplysinella rhax

Oluwabusola, E. T., Tabudravu, J. N., Al Maqbali, K. S., Annang, F., Pérez Moreno, G., Reyes, F. & Jaspars, M., 22 Jul 2020, In : Chemistry & Biodiversity.

Research output: Contribution to journalArticle

Open Access

Asenjonamides A-C, antibacterial metabolites isolated from Streptomyces asenjonii strain KNN 42.f from an extreme-hyper arid Atacama Desert soil

Abdelkader, M. S. A., Philippon, T., Asenjo, J. A., Bull, A. T., Goodfellow, M., Ebel, R., Jaspars, M. & Rateb, M. E., 2018, In : The Journal of antibiotics. 71, p. 425-431 7 p.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
9 Downloads (Pure)

Aspiperidine oxide, a piperidine N-oxide from the filamentous fungus Aspergillus indologenus

Petersen, L. M., Kildgaard, S., Jaspars, M. & Larsen, T. O., 1 Apr 2015, In : Tetrahedron Letters. 56, 14, p. 1847-1850 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A tiered approach to the marine genetic resource governance framework under the proposed UNCLOS agreement for biodiversity beyond national jurisdiction (BBNJ)

Humphries, F., Gottlieb, H. M., Laird, S., Wynberg, R., Lawson, C., Rourke, M., Tvedt, M. W., Oliva, M. J. & Jaspars, M., 9 Mar 2020, In : Marine Policy. 14 p., 103910.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)
2 Downloads (Pure)

A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

Parajuli, A., Kwak, D. H., Dalponte, L., Leikoski, N., Galica, T., Umeobika, U., Trembleau, L., Bent, A., Sivonen, K., Wahlsten, M., Wang, H., Rizzi, E., De Bellis, G., Naismith, J., Jaspars, M., Liu, X., Houssen, W. & Fewer, D. P., 7 Mar 2016, In : Angewandte Chemie. 128, 11, p. 3660-3663 4 p.

Research output: Contribution to journalArticle

Open Access
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17 Citations (Scopus)
10 Downloads (Pure)
Open Access
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1 Downloads (Pure)

Biomedicinals from the Microbial Metagenomes of Marine Invertebrates

Dunlap, W. C., Long, P. F. & Jaspars, M., 10 Nov 2011, Handbook of Molecular Microbial Ecology II: Metagenomics in Different Habitats. John Wiley and Sons, p. 517-544 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Biosynthesis of neocarazostatin A reveals the sequential carbazole prenylation and hydroxylation in the tailoring steps

Huang, S., Elsayed, S. S., Lv, M., Tabudravu, J., Rateb, M. E., Gyampoh, R., Kyeremeh, K., Ebel, R., Jaspars, M., Deng, Z., Yu, Y. & Deng, H., 17 Dec 2015, In : Chemistry & Biology. 22, 12, p. 1633-1642 10 p.

Research output: Contribution to journalArticle

Open Access
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18 Citations (Scopus)
11 Downloads (Pure)

Bromoalkaloids Protect Primary Cortical Neurons from Induced Oxidative Stress

Leiros, M., Alonso, E., Rateb, M. E., Houssen, W. E., Ebel, R., Jaspars, M., Alfonso, A. & Botana, L. M., Feb 2015, In : ACS Chemical Neuroscience. 6, 2, p. 331-338 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Butremycin, the 3-Hydroxyl Derivative of Ikarugamycin and a Protonated Aromatic Tautomer of 5′-Methylthioinosine from a Ghanaian Micromonospora sp. K310

Kyeremeh, K., Acquah, K., Sazak, A., Houssen, W. E., Tabudravu, J., Deng, H. & Jaspars, M., 14 Feb 2014, In : Marine Drugs. 12, 2, p. 999-1012 13 p., 12.

Research output: Contribution to journalArticle

Open Access
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31 Citations (Scopus)
6 Downloads (Pure)

Butrepyrazinone, a New Pyrazinone with an Unusual Methylation Pattern from a Ghanaian Verrucosispora sp. K51G

Kyeremeh, K., Acquah, K., Camas, M., Tabudravu, J., Houssen, W. E., Deng, H. & Jaspars, M., 16 Oct 2014, In : Marine Drugs. 12, 10, p. 5197-5208 12 p.

Research output: Contribution to journalArticle

Open Access
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19 Citations (Scopus)
6 Downloads (Pure)

Bypassing the proline/thiazoline requirement of the macrocyclase PatG

Oueis, E., Stevenson, H., Jaspars, M., Westwood, N. J. & Naismith, J. H., 25 Nov 2017, In : Chemical Communications. 53, 91, p. 12274-12277 4 p.

Research output: Contribution to journalArticle

Open Access
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11 Citations (Scopus)
6 Downloads (Pure)

Chaxamycins A-D, Bioactive Ansamycins from a Hyper-arid Desert Streptomyces sp

Rateb, M. E., Houssen, W. E., Arnold, M., Abdelrahman, M. H., Deng, H., Harrison, W. T. A., Okoro, C. K., Asenjo, J. A., Andrews, B. A., Ferguson, G., Bull, A. T., Goodfellow, M., Ebel, R. & Jaspars, M., Jun 2011, In : Journal of Natural Products. 74, 6, p. 1491-1499 9 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert

Elsayed, S. S., Trusch, F., Deng, H., Raab, A., Prokes, I., Busarakam, K., Asenjo, J. A., Andrews, B. A., van West, P., Bull, A. T., Goodfellow, M., Yi, Y., Ebel, R., Jaspars, M. & Rateb, M. E., 2015, In : Journal of Organic Chemistry. 80, 20, p. 10252-10260 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Citrinadin A derivatives from Penicillium citrinum, an endophyte from the marine red alga Dichotomaria marginata

de JASAndrade, T., Somensi, A., Lopes, M. N., Araujo, A. R., Jaspars, M. & Silva, D. H. S., Jul 2014, In : Planta Medica. 80, 10, p. 776 1 p., PC37.

Research output: Contribution to journalAbstract

Commiphora gileadensis sap extract induces cell cycle-dependent death in immortalized keratinocytes and human dermoid carcinoma

Wineman, E., Douglas, I., Wineman, V., Sharova, K., Jaspars, M., Meshner, S., Bentwich, Z., Cohen, G. & Shtevi, A., Dec 2015, In : Journal of herbal medicine. 5, 4, p. 199-206 8 p.

Research output: Contribution to journalArticle

Open Access
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6 Citations (Scopus)
5 Downloads (Pure)

Contemporary strategies in natural products structure elucidation

Rodríguez, J., Crews, P. & Jaspars, M., 2012, Handbook of Marine Natural Products. Springer Netherlands, p. 423-517 95 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Cutting the cost of HP/HT cleanups: Novel high density cleanup package enables brine reclamation and reduces costs

Richmond, M., Hutton, A., Davidson, M., Howard, S., Frost, B., Leon, S. & Jaspars, M., 13 Jun 2011, Society of Petroleum Engineers - SPE/IADC Drilling Conference and Exhibition 2011. Vol. 2. p. 752-757 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants

Alexandru-Crivac, C. N., Umeobika, C., Leikoski, N., Jokela, J., Rickaby, K., Grilo, A. M., Sjo, P., Plowright, A. T., Idress, M., Siebs, E., Nneoyi-Egbe, A., Wahlsten, M., Sivonen, K., Jaspars, M., Trembleau, L., Fewer, D. P. & Houssen Ibrahim, W. E., 4 Oct 2017, In : Chemical Communications. 53, 77, p. 10656-10659 4 p.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
12 Downloads (Pure)

Cyclic Peptides – A Look to the Future

Idress, M., Alexandru-Crivac, C. N., Jaspars, M., Trembleau, L. A. C., Houssen Ibrahim, W. E-S. M., Rickaby, K. A. & Dalponte, L., 15 Dec 2017, Cyclic Peptides: From Bioorganic Synthesis to Applications . Koehnke, J., Naismith, J. & van der Donk, W. A. (eds.). UK: Royal Society of Chemistry (Great Britain) , p. 340-373 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Decorosides A and B, cytotoxic flavonoid glycosides from the leaves of Rhododendron decorum

Rateb, M. E., Hassan, H. M., Arafa, E-S. A., Jaspars, M., Ebel, R. & Rateb, M. E. M., Apr 2014, In : Natural Product Communications. 9, 4, p. 473-476 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
3 Citations (Scopus)

Dermacozines H-J Isolated from a Deep-Sea Strain of Dermacoccus abyssi from Mariana Trench Sediments

Wagner, M., Abdel-Mageed, W. M., Ebel, R., Bull, A. T., Goodfellow, M., Fiedler, H-P. & Jaspars, M., 22 Feb 2014, In : Journal of Natural Products. 77, 2, p. 416-420 5 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Detection of halogenated tryramine and tyrosine derivatives in extracts of Algoa Bay ascidians

Bromley, C. L., Raab, A., Beukes, D., Feldmann, J., Jaspars, M. & Davies-Coleman, M. T., Jul 2015, In : Planta Medica. 81, 11, p. 914 1 p.

Research output: Contribution to journalAbstract

Discovery of a single monooxygenase catalyzing the carbamate formation and ring contraction in the biosynthesis of legonmycins

Huang, S., Tabudravu, J., Elsayed, S. S., Travert, J., Peace, D., Tong, M. H., Kyeremeh, K., Kelly, S., Trembleau, L. A. C., Ebel, R. P., Jaspars, M., Yu, Y. & Deng, H., 19 Oct 2015, In : Angewandte Chemie International Edition. 54, 43, p. 12697-12701 4 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
6 Downloads (Pure)

Disruption of a methyltransferase gene in actinomycin G gene cluster in Streptomyces iakyrus increases the production of phenazinomycin

Qin, Z., Wang, X., Rateb, M., Ass'ad, L. A., Jaspars, M., Deng, Z., Yu, Y. & Deng, H., Mar 2014, In : FEMS Microbiology Letters. 352, 1, p. 62-68 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment

Rateb, M. E., Houssen, W. E., Harrison, W. T. A., Deng, H., Okoro, C. K., Asenjo, J. A., Andrews, B. A., Bull, A. T., Goodfellow, M., Ebel, R. & Jaspars, M., 23 Sep 2011, In : Journal of Natural Products. 74, 9, p. 1965-1971 7 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Diversity of organic structures of marine microbial origin with drug potential

Jaspars, M., Ebel, R. P. & Deng, H., 2015, Phycotoxins: Chemistry and Biochemistry. Botana, LM. & Alfonso, A. (eds.). 2 ed. Blackwell Science, p. 361-380 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Downsizing Class II Lasso Peptides: Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle

Cortés-Albayay, C., Jarmusch, S. A., Trusch, F., Ebel, R., Andrews, B. A., Jaspars, M. & Asenjo, J. A., 7 Feb 2020, In : Journal of Organic Chemistry. 85, 3, p. 1661-1667 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Draft Genome Sequence of Aneurinibacillus migulanus NCTC 7096

Alenezi, F. N., Weitz, H. J., Belbahri, L., Nidhal, J., Luptakova, L., Jaspars, M. & Woodward, S., 2 Apr 2015, In : Genome Announcements. 3, 2, 1 p., e00234-15.

Research output: Contribution to journalArticle

Open Access
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9 Citations (Scopus)
9 Downloads (Pure)

Draft Genome Sequence of Aneurinibacillus migulanus Strain Nagano

Alenezi, F. N., Weitz, H. J., Belbahri, L., Ben Rebah, H., Luptakova, L., Jaspars, M. & Woodward, S., 2 Apr 2015, In : Genome Announcements. 3, 2, 1 p., e00232-15.

Research output: Contribution to journalArticle

Open Access
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8 Citations (Scopus)
6 Downloads (Pure)

Draft Genome Sequence of Streptomyces sp. Strain CT34, Isolated from a Ghanaian Soil Sample

Zhai, Y., Cheng, B., Hu, J., Kyeremeh, K., Wang, X., Jaspars, M., Deng, H., Deng, Z-X. & Hong, K., 2015, In : Genome Announcements. 3, 1, 01508-14.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
8 Downloads (Pure)

Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation

Wakefield, J., Hassan, H. M., Jaspars, M., Ebel, R. & Rateb, M. E., 11 Jul 2017, In : Frontiers in Microbiology. 8, p. 1-10 10 p., 1284.

Research output: Contribution to journalArticle

Open Access
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37 Citations (Scopus)
10 Downloads (Pure)

Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics

Oueis, E., Jaspars, M., Westwood, N. J. & Naismith, J. H., 4 May 2016, In : Angewandte Chemie International Edition. 55, 19, p. 5842-5845 4 p.

Research output: Contribution to journalArticle

Open Access
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30 Citations (Scopus)
9 Downloads (Pure)

Evaluation of the Antioxidant Activity of the Marine Pyrroloiminoquinone Makaluvamines

Alonso, E., Alvariño, R., Leirós, M., Tabudravu, J. N., Feussner, K., Dam, M. A., Rateb, M. E., Jaspars, M. & Botana, L. M., 27 Oct 2016, In : Marine Drugs. 14, 11, 197.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
8 Downloads (Pure)