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  • Graeme Murray

A Comparison of Tumour Characteristics and Oncological Outcomes in Patients with Screen-Detected and Symptomatic Colorectal Polyp Cancers

Colleran, R., Ramsay, G., Mackay, C., Parnaby, C. N. & Murray, G. I., Jun 2017.

Research output: Contribution to conferencePoster

Cellular apoptosis susceptibility (chromosome segragation 1-like, CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer

Alnabulsi, A., Agouni, A., Mitra, S., Garcia-Murillas, I., Carpenter, B., Bird, S. & Murray, G. I., Dec 2012, In : The Journal of pathology. 228, 4, p. 471-481 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer

Swan, R., Alnabulsi, A., Cash, B., Alnabulsi, A. & Murray, G. I., 22 Jun 2016, In : Oncotarget. 7, 29, p. 46509-46527 19 p., 10224.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
6 Downloads (Pure)

Colorectal tumors require NUAK1 for protection from oxidative stress

Port, J. L. F., Muthalagu, N., Raja, M., Ceteci, F., Monteverde, T., Kruspig, B., Hedley, A., Kalna, G., Lilla, S., Neilson, L., Brucoli, M., Gyuraszova, K., Tait-Mulder, J., Mezna, M., Svambaryte, S., Bryson, A., Sumpton, D., McVie, A., Nixon, C., Drysdale, M. & 5 others, Esumi, H., Murray, G. I., Sansom, O. J., Zanivan, S. & Murphy, D. J., May 2018, In : Cancer Discovery. 8, 5, p. 633-647 15 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
6 Downloads (Pure)

Combined linkage and association analysis of classical Hodgkin lymphoma

Lawrie, A., Han, S., Sud, A., Hosking, F., Cezard, T., Turner, D., Clark, C., Murray, G. I., Culligan, D. J., Houlston, R. S. & Vickers, M. A., 17 Apr 2018, In : Oncotarget. 9, 29, p. 20377-20385 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
9 Downloads (Pure)

Current concepts in tumour-derived organoids

Porter, R. J., Murray, G. & McLean, M. H., 13 Oct 2020, In : British Journal of Cancer. 123, p. 1209-1218 10 p.

Research output: Contribution to journalArticle

Dectin-1 is not required for controlling Candida albicans colonisation of the gastrointestinal tract

Vautier, S., Drummond, R. A., Redelinghuys, P., Murray, G. I., Maccallum, D. M. & Brown, G. D., Dec 2012, In : Infection and Immunity. 80, 12, p. 4216-4222 7 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Le Sommer, S., Morrice, N., Pesaresi, M., Thompson, D., Vickers, M. A., Murray, G. I., Mody, N., Neel, B. G., Bence, K. K., Wilson, H. M. & Delibegovic, M., Jan 2018, In : Cancer Research. 78, 1, p. 75-87 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
9 Downloads (Pure)

Drug Transporter Gene Expression in Human Colorectal Tissue and Cell Lines: Modulation with Antiretrovirals for Microbicide Optimization

Mukhopadhya, I., Murray, G. I., Berry, S., Thomson, J., Frank, B., Gwozdz, G., Ekeruche-Makinde, J., Shattock, R., Kelly, C., Iannelli, F., Pozzi, G., El-Omar, E. M., Hold, G. L. & Hijazi, K., Feb 2016, In : Journal of Antimicrobial Chemotherapy. 71, 2, p. 372-386 15 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
12 Downloads (Pure)

Enterohepatic Helicobacter in ulcerative colitis: potential pathogenic entities?

Thomson, J. M., Hansen, R., Berry, S. H., Hope, M. E., Murray, G. I., Mukhopadhya, I., McLean, M. H., Shen, Z., Fox, J. G., El-Omar, E. & Hold, G. L., 23 Feb 2011, In : PloS ONE. 6, 2, 9 p., e17184.

Research output: Contribution to journalArticle

Open Access
File
56 Citations (Scopus)
6 Downloads (Pure)

Exploiting differential Wnt target gene expression to generate a molecular biomarker for colorectal cancer stratification

Kleeman, S. O., Koelzer, V. H., Jones, H. J. S., Vazquez, E. G., Davis, H., East, J. E., Arnold, R., Koppens, M. A. J., Blake, A., Domingo, E., Cunningham, C., Beggs, A. D., Pestinger, V., Loughrey, M. B., Wang, L-M., Lannagan, T. R. M., Woods, S. L., Worthley, D., The S:CORT Consortium, Tomlinson, I. & 3 others, Dunne, P. D., Maughan, T. & Leedham, S. J., May 2020, In : Gut. 69, p. 1092-1103 12 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
1 Downloads (Pure)

Expression of neutrophil gelatinase-associated lipocalin in colorectal neoplastic progression: a marker of malignant potential?

McLean, M. H., Thomson, A. J., Murray, G. I., Fyfe, N., Hold, G. L. & El-Omar, E. M., 25 Jun 2013, In : British Journal of Cancer. 108, 12, p. 2537-2541 5 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
32 Downloads (Pure)

Extending colonic mucosal microbiome analysis - Assessment of colonic lavage as a proxy for endoscopic colonic biopsies

Watt, E., Gemmell, M. R., Berry, S., Glaire, M., Farquharson, F., Louis, P., Murray, G. I., El-Omar, E. & Hold, G. L., 25 Nov 2016, In : Microbiome. 4, 61.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
9 Downloads (Pure)

Extensive esophageal papillomatosis after chemoradiotherapy for squamous cell carcinoma

Siu, W., Murray, G. I., McKinlay, A. & Phull, P., Jun 2018, In : Gastrointestinal Endoscopy. 87, 6, p. 1581-1582 2 p.

Research output: Contribution to journalArticle

Familial collagenous colitis involving a 6-year old child

Phull, P., Vijayan, B., Bisset, W. M. & Murray, G. I., Jun 2012, In : Journal of Crohn's and Colitis. 6, 5, p. 606-609 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Following the protein biomarker trail to colorectal cancer

Coghlin, C. & Murray, G. I., Apr 2012, In : Colorectal cancer. 1, 2, p. 93-96 4 p.

Research output: Contribution to journalEditorial

Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer

Petty, R. D., Dahle-Smith, A., Stevenson, D. A. J., Osborne, A., Massie, D., Clark, C., Murray, G. I., Dutton, S. J., Roberts, C., Chong, I. Y., Mansoor, W., Thompson, J., Harrison, M., Chatterjee, A., Falk, S., Elyan, S., Garcia-Alonso, A., Fyfe, D. W., Wadsley, J., Chau, I. & 2 others, Ferry, D. & Miedzybrodzka, Z., Jul 2017, In : Journal of Clinical Oncology. 35, 20, p. 2279-2287 9 p.

Research output: Contribution to journalArticle

Open Access
48 Citations (Scopus)

Has the proteome of formalin-fixed wax embedded tissue been unlocked?

Murray, G. I., Sep 2012, In : Nephrology Dialysis Transplantation. 27, 9, p. 3395-3398 4 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

Sirinukunwattana, K., Domingo, E., Richman, S., Redmond, K. L., Blake, A., Verrill, C., Leedham, S. J., Chatzipli, A., Hardy, C., Whalley, C., Wu, C-H., Beggs, A. D., McDermott, U., Dunne, P. D., Meade, A. A., Walker, S. M., Murray, G., Samuel, L. M., Seymour, M., Tomlinson, I. & 4 others, Quirke, P., Maughan, T., Rittscher, J. & Koelzer, V. H., 20 Jul 2020, In : Gut.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Immune status is prognostic for poor survival in colorectal cancer patients and is associated with tumour hypoxia

Craig, S. G., Humphries, M. P., Alderdice, M., Bingham, V., Richman, S. D., Loughrey, M. B., Coleman, H. G., Viratham-Pulsawatdi, A., McCombe, K., Murray, G. I., Blake, A., Domingo, E., Robineau, J., Brown, L., Fisher, D., Seymour, M. T., Quirke, P., Bankhead, P., McQuaid, S., Lawler, M. & 4 others, McArt, D. G., Maughan, T. S., James, J. A. & Salto-Tellez, M., 13 Oct 2020, In : British Journal of Cancer. 123, p. 1280-1288 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Increased lymph node yield in colorectal cancer is not necessarily associated with a greater number of lymph node positive cancers

O'Shea, A., Aly, O., Parnaby, C. N., Loudon, M. A., Samuel, L. M. & Murray, G. I., 13 Aug 2014, In : PloS ONE. 9, 8, 10 p., e104991.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
126 Downloads (Pure)

Influence of HPV type on prognosis in patients diagnosed with invasive cervical cancer

Cuschieri, K., Brewster, D. H., Graham, C., Nicoll, S., Williams, A. R. W., Murray, G. I., Millan, D. & Cubie, H. A., Dec 2014, In : International Journal of Cancer. 135, 11, p. 2721-2726 56 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Integrative analysis of the colorectal cancer proteome: potential clinical impact

Alnabulsi, A. & Murray, G. I., Oct 2016, In : Expert Review of Proteomics. 13, 10, p. 917-927 11 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
8 Downloads (Pure)

Isolated tuberculosis of the liver: a diagnostic challenge

Malik, M., Kurban, L., Murray, G. I. & Alkari, B., 2011, (Accepted/In press) In : BMJ Case Reports.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Is the number of lymph nodes retrieved in laparoscopic colorectal cancer resections related to the learning curve of the surgeon?

Aly, O., McDonald, E., Watkins, C., Murray, G. I. & Aly, E. H., 2012, In : Journal of Solid Tumors. 2, 1, p. 16-21 6 p.

Research output: Contribution to journalArticle

Open Access

Laser capture microdissection: Methods and protocols

Murray, G. I., 2011, 2nd ed. New York: Humana Press. 489 p.

Research output: Book/ReportBook

Laser Capture Microdissection: Methods and Protocols

Murray, G. I. (ed.), 2018, 3rd ed. Humana Press. 412 p. (Methods in Molecular Biology; vol. 1723)

Research output: Book/ReportBook

Loss of sensory and noradrenergic innervation in benign colorectal adenomatous polyps-a putative role of semaphorins 3F and 3A

Graf, N., McLean, M. H., Capellino, S., Scholmerich, J., Murray, G. I., El-Omar, E. M. & Straub, R. H., Feb 2012, In : Neurogastroenterology and Motility. 24, 2, p. 120-e83 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis

Baker, A-M., Bird, D., Welti, J. C., Gourlaouen, M., Lang, G., Murray, G. I., Reynolds, A. R., Cox, T. R. & Erler, J. T., 15 Jan 2013, In : Cancer Research. 73, 2, p. 583-594 12 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

MICL controls inflammation in rheumatoid arthritis

Redelinghuys, P., Whitehead, L., Augello, A., Drummond, R. A., Levesque, J-M., Vautier, S., Reid, D. M., Kerscher, B., Taylor, J. A., Nigrovic, P. A., Wright, J., Murray, G. I., Willment, J. A., Hocking, L. J., Fernandes, M. J. G., De Bari, C., McInnes, I. B. & Brown, G. D., Jul 2016, In : Annals of the Rheumatic Diseases. 75, 7, p. 1386-1391 6 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
10 Downloads (Pure)

Molecular profiling of signet ring cell colorectal cancer provides a strong rationale for genomic targeted and immune checkpoint inhibitor therapies

Alvi, M. A., Loughrey, M. B., Dunne, P., McQuaid, S., Turkington, R., Fuchs, M-A., McGready, C., Bingham, V., Pang, B., Moore, W., Maxwell, P., Lawler, M., James, J. A., Murray, G. I., Wilson, R. H. & Salto-Tellez, M., 11 Jul 2017, In : British Journal of Cancer. 117, 2, p. 203-209 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
9 Downloads (Pure)

Natural killer-like signature observed post therapy in locally advanced rectal cancer is a determinant of pathological response and improved survival

Alderdice, M., Dunne, P. D., Cole, A. J., O'Reilly, P. G., McArt, D. G., Bingham, V., Fuchs, M-A., McQuaid, S., Loughrey, M. B., Murray, G. I., Samuel, L., Lawler, M., Wilson, R. H., Salto-Tellez, M. & Coyle, V. M., Sep 2017, In : Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 30, 9, p. 1287-1298 12 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
9 Downloads (Pure)

Novel biomarkers for risk stratification of Barrett’s oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype

Porter, R. J., Murray, G. I., Price, D. P., Petty, R. D. & McLean, M. H., 18 Feb 2020, In : British Journal of Cancer. 122, p. 545-554 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
2 Downloads (Pure)

Optimized response prediction in esophagogastric junction adenocarcinomas (EGJAc) with combination of molecular biomarkers and FDG-PET

Petty, R. D., Bain, G., Murray, G. I., Gilbert, F., Denison, A. R., McKiddie, F. I., Ahearn, T., Leeds, J., Phull, P., Park, K., Welch, A., Schweiger, L. F. & Collie-Duguid, E. S. R., 2012, In : Journal of Clinical Oncology. 30, Suppl. 4, 1.

Research output: Contribution to journalAbstract

Prognostic Value of Lymph Node Ratio and Extramural Vascular Invasion on Overall Survival for Patients Undergoing Curative Colon Cancer Resection

Parnaby, C., Scott, N., Mackay, C., Ramsay, G., Guha, A., Samuel, L., Murray, G. I. & Loudon, M., 2014, In : Colorectal Disease. 16, s2, p. 167 1 p., W045.

Research output: Contribution to journalAbstract

23 Citations (Scopus)

Progress in biomarkers of colorectal cancer

Coghlin, C. L. & Murray, G. I., 2013, In : Clinical Laboratory International. 37, p. 10 12 p.

Research output: Contribution to journalEditorial

Progress in the development of protein biomarkers of oesophageal and gastric cancers

Coghlin, C. & Murray, G. I., Apr 2016, In : Proteomics. Clinical applications. 10, 4, p. 532-545 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Progress in the identification of plasma biomarkers of colorectal cancer

Coghlin, C. & Murray, G. I., Aug 2013, In : Proteomics. 13, 15, p. 2227-2228 2 p.

Research output: Contribution to journalLiterature review

15 Citations (Scopus)

Proteomics for early detection of colorectal cancer: recent updates

Alnabulsi, A. & Murray, G. I., 2018, In : Expert Review of Proteomics. 15, 1, p. 55-63 9 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
7 Downloads (Pure)

Proteomics of bone and soft tissue sarcomas

Dundas, S. & Murray, G. I., 2012, In : Current Proteomics. 9, 2, p. 94-102 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Raf kinase inhibitor protein expression combined with peritoneal involvement and lympho-vascular invasion predicts prognosis in Dukes B colorectal cancer patients.

Doyle, B., Hagan, S., Al-Mulla, F., Scott, L., Harden, S., Paul, J., Mulcahy, H., Murray, G. I., Sheahan, K., O'Sullivan, J. & Kolch, W., Feb 2013, In : Histopathology. 62, 3, p. 505-510 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Recent advances in understanding the roles of matrix metalloproteinases in tumour invasion and metastasis

Conlon, G. A. & Murray, G. I., Apr 2019, In : The Journal of pathology. 247, 5, p. 629-640 12 p.

Research output: Contribution to journalArticle

Open Access
File
39 Citations (Scopus)
2 Downloads (Pure)

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation

Lourenco, F. C., Munro, J., Brown, J., Cordero, J., Stefanatos, R., Strathdee, K., Orange, C., Feller, S. M., Sansom, O. J., Vidal, M., Murray, G. I. & Olson, M. F., Mar 2014, In : Gut. 63, 3, p. 480-493 14 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
7 Downloads (Pure)

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

Myant, K. B., Cammereri, P., McGhee, E. J., Ridgway, R. A., Huels, D. J., Cordero, J. B., Schwitalla, S., Kalna, G., Ogg, E-L., Athineos, D., Timpson, P., Vidal, M., Murray, G. I., Greten, F. R., Anderson, K. I. & Sansom, O. J., 6 Jun 2013, In : Cell Stem Cell. 12, 6, p. 761-773 13 p.

Research output: Contribution to journalArticle

217 Citations (Scopus)

Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes

Alexandrou, C., Al-Aqbi, S. S., Higgins, J. A., Boyle, W., Karmokar, A., Andreadi, C., Luo, J-L., Moore, D. A., Viskaduraki, M., Blades, M., Murray, G. I., Howells, L. M., Thomas, A., Brown, K., Cheng, P. N. & Rufini, A., 14 Aug 2018, In : Scientific Reports. 8, p. 1-14 14 p., 12096.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
6 Downloads (Pure)

The adaptive immune and immune checkpoint landscape of neoadjuvant treated esophageal adenocarcinoma using digital pathology quantitation

Humphries, M. P., Craig, S. G., Kacprzyk, R., Fisher, N. C., Bingham, V., McQuaid, S., Murray, G. I., McManus, D., Turkington, R. C., James, J. & Salto-Tellez, M., 1 Jun 2020, In : BMC Cancer. 20, 11 p., 500.

Research output: Contribution to journalArticle

Open Access
File
2 Downloads (Pure)
Open Access
File
10 Citations (Scopus)
10 Downloads (Pure)
Open Access
File
12 Citations (Scopus)
8 Downloads (Pure)

The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer

Brown, G. T., Cash, B. G., Blihoghe, D., Johansson, P., Alnabulsi, A. & Murray, G. I., 7 Mar 2014, In : PloS ONE. 9, 3, 12 p., e90776.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
5 Downloads (Pure)