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Analysis of the relationship between the KRAS G12V oncogene and the Hippo effector YAP1 in embryonal rhabdomyosarcoma
Mohamed, A. D., Shah, N., Hettmer, S., Vargesson, N. & Wackerhage, H., 23 Oct 2018, In: Scientific Reports. 8, 10 p., 15674.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)9 Downloads (Pure) -
A new mammalian model system for thalidomide teratogenesis: Monodelphis domestica
Sorensen, D., Sackett, A., Urban, D. J., Maier, J., Vargesson, N. & Sears, K. E., Jun 2017, In: Reproductive Toxicology. 70, p. 126-132 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)6 Downloads (Pure) -
Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs
Peach, M. L., Beedie, S-L., Chau, C. H., Collins, M. K., Markolovic, S., Luo, W., Tweedie, D., Steinebach, C., Greig, N. H., Gütschow, M., Vargesson, N., Nicklaus, M. C. & Figg, W. D., 2 Dec 2020, In: Molecules. 25, 23, 18 p., 5683.Research output: Contribution to journal › Article › peer-review
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Arterial dysgenesis and limb defects: Clinical and experimental examples
Vargesson, N. & Hootnick, D. R., 1 Jun 2017, In: Reproductive Toxicology. 70, p. 21-29 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)10 Downloads (Pure) -
Common and Distinctive Functions of the Hippo Effectors Taz and Yap in Skeletal Muscle Stem Cell Function
Sun, C., De Mello, V., Mohamed, A., Quiroga, H. P. O., Garcia-Munoz, A., Al Bloshi, A., Tremblay, A. M., von Kriegsheim, A., Collie-Duguid, E., Vargesson, N., Matallanas, D., Wackerhage, H. & Zammit, P. S., 1 Aug 2017, In: Stem Cells. 35, 8, p. 1958-1972 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Citations (Scopus)11 Downloads (Pure) -
Congenital Embryonic Arterial and Skeletal Dysgeneses
Hootnick, D. R., DeSesso, J. & Vargesson, N., Jul 2016, In: RadioGraphics. 36, 4, p. 1257-1257 1 p.Research output: Contribution to journal › Letter › peer-review
1 Citation (Scopus) -
CPS49-induced neurotoxicity does not cause limb patterning anomalies in developing chicken embryos
Mahony, C., McMenemy, S., Rafipay, A. J., Beedie, S-L., Rosa Fraga, L., Gutschow, M., Figg, W. D., Erskine, L. & Vargesson, N., 1 Mar 2018, In: Journal of Anatomy. 232, 4, p. 568-574 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)6 Downloads (Pure) -
Design, synthesis and biological assessment of N-adamantyl, substituted adamantyl and noradamantyl phthalimidines for nitrite, TNF-α and angiogenesis inhibitory activities
Luo, W., Tweedie, D., Beedie, S-L., Vargesson, N., Figg, W. D., Greig, N. H. & Scerba, M. T., 1 May 2018, In: Bioorganic & Medicinal Chemistry. 26, 8, p. 1547-1559 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)8 Downloads (Pure) -
Developmental Angiogenesis
Vargesson, N., Jun 2017, In: Reproductive Toxicology. 70, p. 1-2 2 p.Research output: Contribution to journal › Editorial › peer-review
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Embryos, teratogens and birth defects
Vargesson, N., Sep 2017, In: Journal of Anatomy. 231, 3, p. 449 1 p.Research output: Contribution to journal › Abstract › peer-review
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Expression analysis of limb element markers during mouse embryonic development
Rafipay, A., Berg, A. L. R., Erskine, L. & Vargesson, N., 20 Nov 2018, In: Developmental Dynamics. 247, 11, p. 1217-1226 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)7 Downloads (Pure) -
Genetic association and characterization of FSTL5 in isolated clubfoot
Khanshour, A. M., Kidane, Y., Kozlitina, J., Cornelia, R., Rafipay, A., De Mello, V., Weston, M., Paria, N., Khalid, A., Hecht, J. T., Dobbs, M. B., Richards, B. S., Vargesson, N., Kent Hamra, F., Wilson, M., Wise, C., Gurnett, C. A. & Rios, J. J., 15 Nov 2020, In: Human Molecular Genetics. 29, 22, p. 3717-3728 12 p.Research output: Contribution to journal › Article › peer-review
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In Vivo screening and discovery of novel candidate thalidomide analogs in the zebrafish embryo and chicken embryo model systems
Beedie, S. L., Rore, H. M., Barnett, S., Chau, C. H., Luo, W., Greig, N. H., Figg, W. D. & Vargesson, N., 22 Apr 2016, In: Oncotarget. 7, 22, p. 33237-33245 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)5 Downloads (Pure) -
Knockdown of Slit signalling during limb development leads to a reduction in humerus length
Rafipay, A., Dun, X-P., Parkinson, D. B., Erskine, L. & Vargesson, N., 21 Dec 2020, In: Developmental Dynamics. 38 p.Research output: Contribution to journal › Article › peer-review
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Lens-regulated retinoic acid signalling controls expansion of the developing eye
Smith, J. N., Walker, H. M., Thompson, H., Collinson, J. M., Vargesson, N. & Erskine, L., 10 Oct 2018, In: Development. 145, 19, 13 p., dev167171.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)3 Downloads (Pure) -
Limbal epithelial stem cell activity and corneal epithelial cell cycle parameters in adult and aging mice
Sagga, N., Kuffova, L., Vargesson, N., Erskine, L. & Collinson, J. M., 31 Dec 2018, In: Stem Cell Research. 33, p. 185-198 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)6 Downloads (Pure) -
Molecular analysis of regulative events in the developing chick limb
Mahony, C. & Vargesson, N., 1 Jul 2013, In: Journal of Anatomy. 223, 1, p. 1-13 13 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro
Mahony, C., Erskine, L., Niven, J., Greig, N. H., Figg, W. D. & Vargesson, N., 30 Jul 2013, In: PNAS. 110, 31, p. 12703-12708 6 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Positional Information – a concept underpinning our understanding of developmental biology
Vargesson, N., 1 Mar 2020, In: Developmental Dynamics. 249, 3, p. 298-312 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus) -
Quantitative assessment of intrinsic noise for visually guided behaviour in zebrafish
Spilioti, M., Vargesson, N. & Neri, P., Oct 2016, In: Vision Research. 127, p. 104-114 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
Regarding a limb with PFFD, fibular dimelia and mirror foot deformity
Hootnick, D. R., Vargesson, N. & Birch, J., 1 Nov 2017, In: Journal of Pediatric Orthopaedics B. 26, 6, p. 589-589 1 p.Research output: Contribution to journal › Letter › peer-review
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Reply to D’Amato et al. and Zeldis et al. Screening of thalidomide derivatives in chicken and zebrafish embryos
Vargesson, N., Mahony, C., Erskine, L., Niven, J., Greig, N. H. & Figg, W. D., 10 Dec 2013, In: PNAS. 110, 50, E4820.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Role of cereblon in angiogenesis and in mediating the antiangiogenic activity of immunomodulatory drugs
Beedie, S. L., Huang, P. A., Harris, E. M., Strope, J. D., Mahony, C., Chau, C. H., Vargesson, N. & Figg, W. D., 1 Sep 2020, In: The FASEB Journal. 34, 9, p. 11395-11404 10 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Shared mechanism of teratogenicity of anti-angiogenic drugs identified in the chicken embryo model
Beedie, S. L., Mahony, C., Walker, H. M., Chau, C. H., Figg, W. D. & Vargesson, N., 22 Jul 2016, In: Scientific Reports. 6, p. 1-10 10 p., 30038.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)6 Downloads (Pure) -
Teratogenesis
Vargesson, N. & Fraga, L., 15 Dec 2017, In: eLS. p. 1-7 7 p., a0026056.Research output: Contribution to journal › Article › peer-review
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Thalidomide
Vargesson, N., 21 Apr 2017, Reproductive and Developmental Toxicology . Gupta, R. C. (ed.). 2nd ed. Academic Press, p. 467-479 13 p. Chapter 26Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Thalidomide and birth defects
Fraga, L., Diamond, A. & Vargesson, N., 2016, In: eLS. January 2016, p. 1-11 11 p., a0026052.Research output: Contribution to journal › Article › peer-review
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Thalidomide embryopathy: an enigmatic challenge
Vargesson, N., 2013, In: ISRN Developmental Biology. 2013, 18 p., 241016.Research output: Contribution to journal › Literature review › peer-review
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The chick limb: embryology, genetics and teratology
Davey, M. G., Towers, M., Vargesson, N. & Tickle, C., 19 Mar 2018, In: International Journal of Developmental Biology. 62, p. 85-95 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)6 Downloads (Pure) -
The developmental and genetic basis of ‘clubfoot’ in the peroneal muscular atrophy mutant mouse
Collinson, J. M., Lindstrom, N. O., Neves, C., Wallace, K., Meharg, C., Charles, R., Fraser, A., Mbogo, I., Oras, K., Nakamoto, M., Barker, S., Duce, S., Miedzybrodzka, Z. & Vargesson, N., 8 Feb 2018, In: Development. 145, 3, 15 p., dev160093.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)18 Downloads (Pure) -
'The Legacy of Thalidomide' - a multidisciplinary Meeting held at the University of York, UK on September 30, 2016
Newbronner, E., Vargesson, N. & Atkin, K., 1 Mar 2017, In: Birth Defects Research. 109, 4, p. 296–299 4 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)5 Downloads (Pure) -
The Primodos components Noretheristerone acetate and Ethinyl estradiol induce developmental abnormalities in zebrafish embryos
Brown, S., Rosa Fraga, L., Cameron, G., Erskine, L. & Vargesson, N., 13 Feb 2018, In: Scientific Reports. 8, 14 p., 2917.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)8 Downloads (Pure) -
The syndrome of proximal femur, fibula, and midline metatarsal long bone deficiencies
Hootnick, D. R. & Vargesson, N., 1 Sep 2018, In: Birth Defects Research. 110, 15, p. 1188-1193 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)2 Downloads (Pure) -
The teratogenic effects of thalidomide on limbs
Vargesson, N., 1 Jan 2019, In: Journal of hand surgery-European volume. 44, 1, p. 88-95 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)11 Downloads (Pure) -
Vascular anomalies of the upper limb
Mende, K., Vargesson, N. & Sivakumar, B., 1 Mar 2019, In: Journal of hand surgery-European volume. 44, 3, p. 233-241 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)2 Downloads (Pure) -
VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels
Erskine, L., Francois, U., Denti, L., Joyce, A., Tillo, M., Bruce, F., Vargesson, N. & Ruhrberg, C., 4 Jul 2017, In: Development. 144, 13, p. 2504-2516 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)8 Downloads (Pure) -
Vertebrate embryos as tools for anti-angiogenic drug screening and function
Beedie, S., Diamond, A. J., Rosa Fraga, L., Figg, W. D. & Vargesson, N., 1 Jun 2017, In: Reproductive Toxicology. 70, p. 49-59 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)31 Downloads (Pure) -
Vgll3 interacts with Yap/Taz-Tead1-4-dependent gene expression in skeletal muscle
Figeac, N., Mohamed, A. A. D., Sun, C., Schonfelder, M., Gomez, D., Garcia-Munoz, A., Missiaglia, E., Collie-Duguid, E., De Mello, V., Pobbati, A. V., Jaka, O., Harridge, S. D. R., Hong, W., Shipley, J., Vargesson, N., Zammit, P. S. & Wackerhage, H., Mar 2019, In: European Journal of Translational Myology. 29, 1, p. 53-53 1 p.Research output: Contribution to journal › Abstract › peer-review
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VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle
Figeac, N., Mohamed, A. D., Sun, C., Schönfelder, M., Matallanas, D., Garcia-Munoz, A., Missiaglia, E., Collie-Duguid, E., De Mello, V., Pobbati, A. V., Pruller, J., Jaka, O., Harridge, S. D. R., Hong, W., Shipley, J., Vargesson, N., Zammit, P. S. & Wackerhage, H., 5 Jul 2019, In: Journal of Cell Science. 132, jcs225946 .Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)9 Downloads (Pure)