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  • Article

    Genome-wide association meta-analysis for early age-related macular degeneration highlights novel loci and insights for advanced disease

    Winkler, T. W., Grassmann, F., Brandl, C., Kiel, C., Günther, F., Strunz, T., Weidner, L., Zimmermann, M. E., Korb, C. A., Poplawski, A., Schuster, A. K., Müller-Nurasyid, M., Peters, A., Rauscher, F. G., Elze, T., Horn, K., Scholz, M., Cañadas-Garre, M., McKnight, A. J., Quinn, N., & 5 othersHogg, R. E., Küchenhoff, H., Heid, I. M., Stark, K. J. & Weber, B. H. F., 26 Aug 2020, In: BMC Medical Genomics. 13, 18 p., 120.

    Research output: Contribution to journal › Article › peer-review

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    24 Citations (Scopus)
    1 Downloads (Pure)

  • Genome-wide association of multiple complex traits in outbred mice by ultra low-coverage sequencing

    Nicod, J., Davies, R. W., Cai, N., Hassett, C., Goodstadt, L., Cosgrove, C., Yee, B. K., Lionikaite, V., McIntyre, R. E., Remme, C. A., Lodder, E. M., Gregory, J. S., Hough, T., Joynson, R., Phelps, H., Nell, B., Rowe, C., Wood, J., Walling, A., Bopp, N., & 22 othersBhomra, A., Hernandez-Pliego, P., Callebert, J., Aspden, R. M., Talbot, N. P., Robbins, P. A., Harrison, M., Fray, M., Launay, J-M., Pinto, Y. M., Blizard, D. A., Bezzina, C. R., Adams, D. J., Franken, P., Weaver, T., Wells, S., Brown, S. D. M., Potter, P. K., Klenerman, P., Lionikas, A., Mott, R. & Flint, J., 31 Aug 2016, In: Nature Genetics. 48, 8, p. 912-918 7 p.

    Research output: Contribution to journal › Article › peer-review

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    83 Citations (Scopus)
    10 Downloads (Pure)

  • Genome-wide Associations Reveal Human-Mouse Genetic Convergence and Modifiers of Myogenesis, CPNE1 and STC2

    Hernandez Cordero, A. I., Gonzales, N. M., Parker, C. C., Sokoloff, G., Vandenbergh, D. J., Cheng, R., Abney, M., Sko, A., Douglas, A., Palmer, A. A., Gregory, J. S. & Lionikas, A., 5 Dec 2019, In: American Journal of Human Genetics. 105, 6, p. 1222-1236 15 p.

    Research output: Contribution to journal › Article › peer-review

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    21 Citations (Scopus)
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  • Genomewide association studies: History, rationale, and prospects for psychiatric disorders

    Cichon, S., Craddock, N., Daly, M., Faraone, S. V., Gejman, P. V., Kelsoe, J., Lehner, T., Levinson, D. F., Moran, A., Sklar, P., Sullivan, P. F. & Psychiatric GWAS Consortium Coordinating Committee, 1 May 2009, In: American Journal of Psychiatry. 166, 5, p. 540-556 17 p.

    Research output: Contribution to journal › Article › peer-review

    336 Citations (Scopus)

  • Genome-wide association studies establish that human intelligence is highly heritable and polygenic

    Davies, G., Tenesa, A., Payton, A., Yang, J., Harris, S. E., Liewald, D., Ke, X., Le Hellard, S., Christoforou, A., Luciano, M., McGhee, K., Lopez, L., Gow, A. J., Corley, J., Redmond, P., Fox, H. C., Haggarty, P., Whalley, L. J., McNeill, G., Goddard, M. E., & 12 othersEspeseth, T., Lundervold, A. J., Reinvang, I., Pickles, A., Steen, V. M., Ollier, W., Porteous, D. J., Horan, M., Starr, J. M., Pendleton, N., Visscher, P. M. & Deary, I. J., Oct 2011, In: Molecular Psychiatry. 16, 10, p. 996-1005 10 p.

    Research output: Contribution to journal › Article › peer-review

    458 Citations (Scopus)

  • Genome-wide association studies identify heavy metal ATPase3 as the primary determinant of natural variation in leaf cadmium in Arabidopsis thaliana

    Chao, D-Y., Silva, A., Baxter, I., Huang, Y. S., Nordborg, M., Danku, J., Lahner, B., Yakubova, E. & Salt, D. E., 6 Sep 2012, In: PLoS Genetics. 8, 9, 14 p., e1002923.

    Research output: Contribution to journal › Article › peer-review

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    182 Citations (Scopus)
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  • Genome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis

    Gharahkhani, P., Fitzgerald, R. C., Vaughan, T. L., Palles, C., Gockel, I., Tomlinson, I., Buas, M. F., May, A., Gerges, C., Anders, M., Becker, J., Kreuser, N., Noder, T., Venerito, M., Veits, L., Schmidt, T., Manner, H., Schmidt, C., Hess, T., Böhmer, A. C., & 30 othersIzbicki, J. R., Hölscher, A. H., Lang, H., Lorenz, D., Schumacher, B., Hackelsberger, A., Mayershofer, R., Pech, O., Vashist, Y., Ott, K., Vieth, M., Weismüller, J., Nöthen, M. M., Attwood, S., Barr, H., Chegwidden, L., de Caestecker, J., Harrison, R., Love, S. B., MacDonald, D., Moayyedi, P., Prenen, H., Watson, R. G. P., Iyer, P. G., Anderson, L. A., Bernstein, L., Chow, W. H., Hardie, L. J., Lagergren, J. & Liu, G., 1 Oct 2016, In: The Lancet Oncology. 17, 10, p. 1363-1373 11 p.

    Research output: Contribution to journal › Article › peer-review

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    104 Citations (Scopus)
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  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L., Agerbo, E., & 33 othersAkil, H., Albani, D., Alliey-Rodriguez, N., Als, T. D., Anjorin, A., Antilla, V., Awasthi, S., Badner, J. A., Bækvad-Hansen, M., Barchas, J. D., Bass, N., Bauer, M., Belliveau, R., Bergen, S. E., Pedersen, C. B., Bøen, E., Boks, M. P., Boocock, J., Budde, M., Bunney, W., Burmeister, M., Bybjerg-Grauholm, J., Byerley, W., Casas, M., Cerrato, F., Cervantes, P., Chambert, K., Charney, A. W., Chen, D., St Clair, D., eQTLGen Consortium, BIOS Consortium & Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, 1 May 2019, In: Nature Genetics. 51, p. 793-803 11 p.

    Research output: Contribution to journal › Article › peer-review

    706 Citations (Scopus)

  • Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

    Watson, H. J., Yilmaz, Z., Thornton, L. M., Hübel, C., Coleman, J. R. I., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Medland, S. E., Ripke, S., Yao, S., Giusti-Rodríguez, P., Hanscombe, K. B., Purves, K. L., Adan, R. A. H., Alfredsson, L., Ando, T., Andreassen, O. A., & 192 othersBaker, J. H., Berrettini, W. H., Boehm, I., Boni, C., Perica, V. B., Buehren, K., Burghardt, R., Cassina, M., Cichon, S., Clementi, M., Cone, R. D., Courtet, P., Crow, S., Crowley, J. J., Danner, U. N., Davis, O. S. P., de Zwaan, M., Dedoussis, G., Degortes, D., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Dmitrzak-Weglarz, M., Docampo, E., Duncan, L. E., Egberts, K., Ehrlich, S., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Favaro, A., Fernández-Aranda, F., Fichter, M. M., Fischer, K., Föcker, M., Foretova, L., Forstner, A. J., Forzan, M., Franklin, C. S., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Mayora, M. G., Guillaume, S., Guo, Y., Hakonarson, H., Hatzikotoulas, K., Hauser, J., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Huckins, L. M., Hudson, J. I., Imgart, H., Inoko, H., Janout, V., Jiménez-Murcia, S., Julià, A., Kalsi, G., Kaminská, D., Kaprio, J., Karhunen, L., Karwautz, A., Kas, M. J. H., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Kim, Y-R., Klareskog, L., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Levitan, R. D., Li, D., Lilenfeld, L., Lin, B. D., Lissowska, J., Luykx, J., Magistretti, P. J., Maj, M., Mannik, K., Marsal, S., Marshall, C. R., Mattingsdal, M., McDevitt, S., McGuffin, P., Metspalu, A., Meulenbelt, I., Micali, N., Mitchell, K., Monteleone, A. M., Monteleone, P., Munn-Chernoff, M. A., Nacmias, B., Navratilova, M., Ntalla, I., O’Toole, J. K., Ophoff, R. A., Padyukov, L., Palotie, A., Pantel, J., Papezova, H., Pinto, D., Rabionet, R., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Santonastaso, P., Scherag, A., Scherer, S. W., Schmidt, U., Schork, N. J., Schosser, A., Seitz, J., Slachtova, L., Slagboom, P. E., Slof-Op ‘t Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Szatkiewicz, J. P., Tachmazidou, I., Tenconi, E., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Wagner, G., Walton, E., Widen, E., Zeggini, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J. E., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, T., Whiteman, D. C., Woodside, D. B., Stuber, G. D., Gordon, S., Grove, J., Henders, A. K., Juréus, A., Kirk, K. M., Larsen, J. T., Parker, R., Petersen, L., Jordan, J., Kennedy, M., Montgomery, G. W., Wade, T. D., Birgegård, A., Lichtenstein, P., Norring, C., Landén, M., Martin, N. G., Mortensen, P. B., Sullivan, P. F., Breen, G., Bulik, C. M., Initiative, A. N. G. & Consortium, E. D. W. G. O. T. P. G., Aug 2019, In: Nature Genetics. 51, p. 1207-1214 8 p.

    Research output: Contribution to journal › Article › peer-review

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    361 Citations (Scopus)
    12 Downloads (Pure)

  • Genome-wide association study identifies five new schizophrenia loci

    Ripke, S., Sanders, A. R., Kendler, K. S., Levinson, D. F., Sklar, P., Holmans, P. A., Lin, D-Y., Duan, J., Ophoff, R. A., Andreassen, O. A., Scolnick, E., Cichon, S., St Clair, D., Corvin, A., Gurling, H., Werge, T., Rujescu, D., Blackwood, D. H. R., Pato, C. N., Malhotra, A. K., & 31 othersPurcell, S., Dudbridge, F., Neale, B. M., Rossin, L., Visscher, P. M., Posthuma, D., Ruderfer, D. M., Fanous, A., Stefansson, H., Steinberg, S., Mowry, B. J., Golimbet, V., De Hert, M., Jönsson, E. G., Bitter, I., Pietiläinen, O. P. H., Collier, D. A., Tosato, S., Agartz, I., Albus, M., Alexander, M., Amdur, R. L., Amin, F., Bass, N., Bergen, S. E., Black, D. W., Børglum, A. D., Brown, M. A., Bruggeman, R., Buccola, N. G. & Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium, Oct 2011, In: Nature Genetics. 43, 10, p. 969-976 8 p.

    Research output: Contribution to journal › Article › peer-review

    1522 Citations (Scopus)

  • Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris

    Navarini, A. A., Simpson, M. A., Weale, M., Knight, J., Carlavan, I., Reiniche, P., Burden, D. A., Layton, A., Bataille, V., Allen, M., Pleass, R., Pink, A., Creamer, D., English, J., Munn, S., Walton, S., Willis, C., Déret, S., Voegel, J. J., Spector, T., & 5 othersSmith, C. H., Trembath, R. C., Barker, J. N., Acne Genetic Study Group & Ormerod, A., 13 Jun 2014, In: Nature Communications. 5, 4020.

    Research output: Contribution to journal › Article › peer-review

    49 Citations (Scopus)

  • Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

    Stahl, E. A., Raychaudhuri, S., Remmers, E. F., Xie, G., Eyre, S., Thomson, B. P., Li, Y., Kurreeman, F. A. S., Zhernakova, A., Hinks, A., Guiducci, C., Chen, R., Alfredsson, L., Amos, C. I., Ardlie, K. G., Barton, A., Bowes, J., Brouwer, E., Burtt, N. P., Catanese, J. J., & 31 othersCoblyn, J., Coenen, M. J. H., Costenbader, K. H., Criswell, L. A., Crusius, J. B. A., Cui, J., de Bakker, P. I. W., De Jager, P. L., Ding, B., Emery, P., Flynn, E., Harrison, P., Hocking, L., Huizinga, T. W. J., Kastner, D. L., Ke, X., Lee, A. T., Liu, X., Martin, P., Morgan, A. W., Padyukov, L., Posthumus, M. D., Radstake, T. R. D. J., Reid, D. M., Seielstad, M., Seldin, M. F., Shadick, N. A., Steer, S., Tak, P. P., Thomson, W. & BIRAC Consortium, YEAR Consortium, Jun 2010, In: Nature Genetics. 42, 6, p. 508-514 7 p.

    Research output: Contribution to journal › Article › peer-review

    991 Citations (Scopus)

  • Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region

    Peters, M. J., Broer, L., Willemen, H. L. D. M., Eiriksdottir, G., Hocking, L. J., Holliday, K. L., Horan, M. A., Meulenbelt, I., Neogi, T., Popham, M., Schmidt, C. O., Soni, A., Valdes, A. M., Amin, N., Dennison, E. M., Eijkelkamp, N., Harris, T. B., Hart, D. J., Hofman, A., Huygen, F. J. P. M., & 32 othersJameson, K. A., Jones, G. T., Launer, L. J., Kerkhof, H. J. M., de Kruijf, M., McBeth, J., Kloppenburg, M., Ollier, W. E., Oostra, B., Payton, A., Rivadeneira, F., Smith, B. H., Smith, A. V., Stolk, L., Teumer, A., Thomson, W., Uitterlinden, A. G., Wang, K., van Wingerden, S. H., Arden, N. K., Cooper, C., Felson, D., Gudnason, V., Macfarlane, G. J., Pendleton, N., Slagboom, P. E., Spector, T. D., Völzke, H., Kavelaars, A., van Duijn, C. M., Williams, F. M. K. & van Meurs, J. B. J., Mar 2013, In: Annals of the Rheumatic Diseases. 72, 3, p. 427-436 10 p.

    Research output: Contribution to journal › Article › peer-review

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    89 Citations (Scopus)
    5 Downloads (Pure)

  • Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines

    Atwell, S., Huang, Y. S., Vilhjalmsson, B. J., Willems, G., Horton, M., Li, Y., Meng, D., Platt, A., Tarone, A. M., Hu, T. T., Jiang, R., Muliyati, N. W., Zhang, X., Amer, M. A., Baxter, I., Brachi, B., Chory, J., Dean, C., Debieu, M., de Meaux, J., & 16 othersEcker, J. R., Faure, N., Kniskern, J. M., Jones, J. D. G., Michael, T., Nemri, A., Roux, F., Salt, D. E., Tang, C., Todesco, M., Traw, M. B., Weigel, D., Marjoram, P., Borevitz, J. O., Bergelson, J. & Nordborg, M., 3 Jun 2010, In: Nature. 465, 7298, p. 627-631 5 p.

    Research output: Contribution to journal › Article › peer-review

    1266 Citations (Scopus)

  • Genomewide association study of acute anterior uveitis identifies new susceptibility loci

    Huang, X. F., Li, Z., de Guzman, E., Robinson, P., Gensler, L., Ward, M. M., Rahbar, M. H., Lee, M. J., Weisman, M. H., Macfarlane, G. J., Jones, G. T., Klingberg, E., Forsblad-D’Elia, H., McCluskey, P., Wakefield, D., Coombes, J. S., Fiatarone Singh, M. A., Mavros, Y., Vlahovich, N., Hughes, D. C., & 11 othersMarzo-Ortega, H., van der Horste-Bruinsma, I., O’Shea, F., Martin, T. M., Rosenbaum, J., Breban, M., Jin, Z. B., Leo, P., Reveille, J. D., Wordsworth, B. P. & Brown, M. A., Jun 2020, In: Investigative Ophthalmology and Visual Science. 61, 6, 12 p., 3.

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    26 Citations (Scopus)

  • Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

    Clarke, T-K., Adams, M. J., Davies, G., Howard, D. M., Hall, L. S., Padmanabhan, S., Murray, A. D., Smith, B. H., Campbell, A., Hayward, C., Porteous, D. J., Deary, I. J. & McIntosh, A. M., Oct 2017, In: Molecular Psychiatry. 22, 10, p. 1376-1384 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    216 Citations (Scopus)
    7 Downloads (Pure)

  • Genome-wide association study of behavioral, physiological and gene expression traits in outbred CFW mice

    Parker, C. C., Gopalakrishnan, S., Carbonetto, P., Gonzales, N. M., Leung, E., Park, Y. J., Aryee, E., Davis, J., Blizard, D. A., Ackert-Bicknell, C. L., Lionikas, A., Pritchard, J. K. & Palmer, A. A., 31 Aug 2016, In: Nature Genetics. 48, 8, p. 919-926 8 p.

    Research output: Contribution to journal › Article › peer-review

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    70 Citations (Scopus)
    5 Downloads (Pure)

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Craddock, N., Hurles, M. E., Cardin, N., Pearson, R. D., Plagnol, V., Robson, S., Vukcevic, D., Barnes, C., Conrad, D. F., Giannoulatou, E., Holmes, C., Marchini, J. L., Stirrups, K., Tobin, M. D., Wain, L. V., Yau, C., Aerts, J., Ahmad, T., Andrews, T. D., Arbury, H., & 31 othersAttwood, A., Auton, A., Ball, S. G., Balmforth, A. J., Barrett, J. C., Barroso, I., Barton, A., Bennett, A. J., Bhaskar, S., Blaszczyk, K., Bowes, J., Brand, O. J., Braund, P. S., Bredin, F., Breen, G. D., Brown, M. J., Bruce, I. N., Bull, J., Burren, O. S., Burton, J., Byrnes, J., Caesar, S., Clee, C. M., Coffey, A. J., Connell, J. M. C., Cooper, J. D., Hocking, L., Reid, D. M., St Clair, D. M., Webster, J. & Wellcome Trust Case Control Consortium, 1 Apr 2010, In: Nature. 464, 7289, p. 713-720 8 p.

    Research output: Contribution to journal › Article › peer-review

    644 Citations (Scopus)

  • Genome-wide association study of major recurrent depression in the U.K. population

    Lewis, C. M., Ng, M. Y., Butler, A. W., Cohen-Woods, S., Uher, R., Pirlo, K., Weale, M. E., Schosser, A., Paredes, U. M., Rivera, M., Craddock, N., Owen, M. J., Jones, L., Jones, I., Korszun, A., Aitchison, K. J., Shi, J., Quinn, J. P., MacKenzie, A., Vollenweider, P., & 13 othersWaeber, G., Heath, S., Lathrop, M., Muglia, P., Barnes, M. R., Whittaker, J. C., Tozzi, F., Holsboer, F., Preisig, M., Farmer, A. E., Breen, G., Craig, I. W. & McGuffin, P., 1 Jun 2010, In: American Journal of Psychiatry. 167, 8, p. 949-957 9 p.

    Research output: Contribution to journal › Article › peer-review

    187 Citations (Scopus)

  • Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.

    Taylor, J. C., Bongartz, T., Massey, J., Mifsud, B., Spiliopoulou, A., Scott, I. C., Wang, J., Morgan, M., Plant, D., Colombo, M., Orchard, P., Twigg, S., McInnes, IB., Porter, D., Freeston, J. E., Nam, J. L., Cordell, H. J., Isaacs, J. D., Strathdee, J. L., Arnett, D. K., & 20 othersde Hair, M. J. H., Tak, P. P., Aslibekyan, S., van Vollenhoven, R. F., Padyukov, L., Bridges, S. L., Pitzalis, C., Cope, A., Verstappen, S. M., Emery, P., Barnes, M. R., Agakov, F., McKeigue, P. M., Mushiroda, T., Kubo, M., Weinshilboum, R., Barton, A., Morgan, A. W., Barrett, J. H. & on behalf of the MATURA, and PAMERA Consortia, 25 May 2018, In: The Pharmacogenomics Journal. 18, p. 528-538

    Research output: Contribution to journal › Article › peer-review

  • Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort

    Xie, G., Myint, P. K., Voora, D., Laskowitz, D. T., Shi, P., Ren, F., Wang, H., Yang, Y., Huo, Y., Gao, W. & Wu, Y., Nov 2015, In: Atherosclerosis. 243, 1, p. 30-37 8 p.

    Research output: Contribution to journal › Article › peer-review

    22 Citations (Scopus)

  • Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer

    Rafnar, T., Sulem, P., Thorleifsson, G., Vermeulen, S. H., Helgason, H., Saemundsdottir, J., Gudjonsson, S. A., Sigurdsson, A., Stacey, S. N., Gudmundsson, J., Johannsdottir, H., Alexiusdottir, K., Petursdottir, V., Nikulasson, S., Geirsson, G., Jonsson, T., Aben, K. K. H., Grotenhuis, A. J., Verhaegh, G. W., Dudek, A. M., & 30 othersAlfred Witjes, J., van der Heijden, A. G., Vrieling, A., Galesloot, T. E., De Juan, A., Panadero, A., Rivera, F., Hurst, C., Timothy Bishop, D., Sak, S. C., Choudhury, A., Teo, M. T. W., Arici, C., Carta, A., Toninelli, E., de Verdier, P., Rudnai, P., Gurzau, E., Koppova, K., van der Keur, K. A., Lurkin, I., Goossens, M., Kellen, E., Guarrera, S., Russo, A., Critelli, R., Sacerdote, C., Vineis, P., Krucker, C. & Kiltie, A. E., 15 Nov 2014, In: Human Molecular Genetics. 23, 20, p. 5545-5557 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Citations (Scopus)

  • Genome-wide expression changes induced by bisphenol A, F and S in human stem cell derived hepatocyte-like cells

    Lucendo-Villarin, B., Nell, P., Hellwig, B., Filis, P., Feuerborn, D., O'Shaughnessy, P. J., Godoy, P., Rahnenführer, J., Hengstler, J. G., Cherianidou, A., Sachinidis, A., Fowler, P. A. & Hay, D. C., Nov 2020, In: EXCLI journal. 19, p. 1459-1476 18 p.

    Research output: Contribution to journal › Article › peer-review

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    3 Citations (Scopus)

  • Genome-wide gene expression profiling and a forward genetic screen show that differential expression of the sodium ion transporter Ena21 contributes to the differential tolerance of Candida albicans and Candida dubliniensis to osmotic stress

    Enjalbert, B., Moran, G. P., Vaughan, C., Yeomans, T., MacCallum, D. M., Quinn, J., Coleman, D. C., Brown, A. J. P. & Sullivan, D. J., Apr 2009, In: Molecular Microbiology. 72, 1, p. 216-228 13 p.

    Research output: Contribution to journal › Article › peer-review

    32 Citations (Scopus)

  • Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank

    Howard, D. M., Hall, L. S., Hafferty, J. D., Zeng, Y., Adams, M. J., Clarke, T-K., Porteous, D. J., Nagy, R., Hayward, C., Smith, B. H., Murray, A. D., Ryan, N. M., Evans, K. L., Haley, C. S., Deary, I. J., Thomson, P. A. & McIntosh, A. M., 2017, In: Translational Psychiatry. 7, 1263.

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  • Genome-wide homozygosity and multiple sclerosis in Orkney and Shetland Islanders

    McWhirter, R. E., McQuillan, R., Visser, E., Counsell, C. & Wilson, J. F., Feb 2012, In: EJHG : European journal of human genetics : the official journal of the European Society of Human Genetics. . 20, 2, p. 198-202 5 p.

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    13 Citations (Scopus)

  • Genome-wide identification of replication origins in yeast by comparative genomics

    Nieduszynski, C. A., Knox, Y. & Donaldson, A. D., Jul 2006, In: Genes & Development. 20, 14, p. 1874-1879 5 p.

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    146 Citations (Scopus)

  • Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain development

    Silvestri, C., Narimatsu, M., von Both, I., Liu, Y., Tan, N. B. J., Izzi, L., McCaffery, P., Wrana, J. L. & Attisano, L., 11 Mar 2008, In: Developmental Cell. 14, 3, p. 411-423 13 p.

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    46 Citations (Scopus)

  • Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

    Generation Scotland & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 20 Dec 2018, In: PloS ONE. 13, 12, e0209160.

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  • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

    Estrada, K., Styrkarsdottir, U., Evangelou, E., Hsu, Y-H., Duncan, E. L., Ntzani, E. E., Oei, L., Albagha, O. M. E., Amin, N., Kemp, J. P., Koller, D. L., Li, G., Liu, C-T., Minster, R. L., Moayyeri, A., Vandenput, L., Willner, D., Xiao, S-M., Yerges-Armstrong, L. M., Zheng, H-F., & 161 othersAlonso, N., Eriksson, J., Kammerer, C. M., Kaptoge, S. K., Leo, P. J., Thorleifsson, G., Wilson, S. G., Wilson, J. F., Aalto, V., Alen, M., Aragaki, A. K., Aspelund, T., Center, J. R., Dailiana, Z., Duggan, D. J., Garcia, M., Garcia-Giralt, N., Giroux, S., Hallmans, G., Hocking, L. J., Husted, L. B., Jameson, K. A., Khusainova, R., Kim, G. S., Kooperberg, C., Koromila, T., Kruk, M., Laaksonen, M., Lacroix, A. Z., Lee, S. H., Leung, P. C., Lewis, J. R., Masi, L., Mencej-Bedrac, S., Nguyen, T. V., Nogues, X., Patel, M. S., Prezelj, J., Rose, L. M., Scollen, S., Siggeirsdottir, K., Smith, A. V., Svensson, O., Trompet, S., Trummer, O., van Schoor, N. M., Woo, J., Zhu, K., Balcells, S., Brandi, M. L., Buckley, B. M., Cheng, S., Christiansen, C., Cooper, C., Dedoussis, G., Ford, I., Frost, M., Goltzman, D., Gonzalez-Macias, J., Kahonen, M., Karlsson, M., Khusnutdinova, E., Koh, J-M., Kollia, P., Langdahl, B. L., Leslie, W. D., Lips, P., Ljunggren, O., Lorenc, R. S., Marc, J., Mellstrom, D., Obermayer-Pietsch, B., Olmos, J. M., Pettersson-Kymmer, U., Reid, D. M., Riancho, J. A., Ridker, P. M., Rousseau, F., Slagboom, P. E., Tang, N. L. S., Urreizti, R., Van Hul, W., Viikari, J., Zarrabeitia, M. T., Aulchenko, Y. S., Castano-Betancourt, M., Grundberg, E., Herrera, L., Ingvarsson, T., Johannsdottir, H., Kwan, T., Li, R., Luben, R., Medina-Gomez, C., Palsson, S. T., Reppe, S., Rotter, J. I., Sigurdsson, G., van Meurs, J. B. J., Verlaan, D., Williams, F. M. K., Wood, A. R., Zhou, Y., Gautvik, K. M., Pastinen, T., Raychaudhuri, S., Cauley, J. A., Chasman, D. I., Clark, G. R., Cummings, S. R., Danoy, P., Dennison, E. M., Eastell, R., Eisman, J. A., Gudnason, V., Hofman, A., Jackson, R. D., Jones, G., Jukema, J. W., Khaw, K-T., Lehtimaki, T., Liu, Y., Lorentzon, M., McCloskey, E., Mitchell, B. D., Nandakumar, K., Nicholson, G. C., Oostra, B. A., Peacock, M., Pols, H. A. P., Prince, R. L., Raitakari, O., Reid, I. R., Robbins, J., Sambrook, P. N., Sham, P. C., Shuldiner, A. R., Tylavsky, F. A., van Duijn, C. M., Wareham, N. J., Cupples, L. A., Econs, M. J., Evans, D. M., Harris, T. B., Kung, A. W. C., Psaty, B. M., Reeve, J., Spector, T. D., Streeten, E. A., Zillikens, M. C., Thorsteinsdottir, U., Ohlsson, C., Karasik, D., Richards, J. B., Brown, M. A., Stefansson, K., Uitterlinden, A. G., Ralston, S. H., Ioannidis, J. P. A., Kiel, D. P. & Rivadeneira, F., May 2012, In: Nature Genetics. 44, 5, p. 491-501 11 p.

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  • Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

    Justice, A. E., Winkler, T. W., Feitosa, M. F., Graff, M., Fisher, V. A., Young, K., Barata, L., Deng, X., Czajkowski, J., Hadley, D., Ngwa, J. S., Ahluwalia, T. S., Chu, A. Y., Heard-Costa, N. L., Lim, E., Perez, J., Eicher, J. D., Kutalik, Z., Xue, L., Mahajan, A., & 297 othersRenström, F., Wu, J., Qi, Q., Ahmad, S., Alfred, T., Amin, N., Bielak, L. F., Bonnefond, A., Bragg, J., Cadby, G., Chittani, M., Coggeshall, S., Corre, T., Direk, N., Eriksson, J., Fischer, K., Gorski, M., Neergaard Harder, M., Horikoshi, M., Huang, T., Huffman, J. E., Jackson, A. U., Justesen, J. M., Kanoni, S., Kinnunen, L., Kleber, M. E., Komulainen, P., Kumari, M., Lim, U., Luan, J., Lyytikäinen, L-P., Mangino, M., Manichaikul, A., Marten, J., Middelberg, R. P. S., Müller-Nurasyid, M., Navarro, P., Pérusse, L., Pervjakova, N., Sarti, C., Smith, A. V., Smith, J. A., Stančáková, A., Strawbridge, R. J., Stringham, H. M., Sung, Y. J., Tanaka, T., Teumer, A., Trompet, S., van der Laan, S. W., van der Most, P. J., Van Vliet-Ostaptchouk, J. V., Vedantam, S. L., Verweij, N., Vink, J. M., Vitart, V., Wu, Y., Yengo, L., Zhang, W., Hua Zhao, J., Zimmermann, M. E., Zubair, N., Abecasis, G. R., Adair, L. S., Afaq, S., Afzal, U., Bakker, S. J. L., Bartz, T. M., Beilby, J., Bergman, R. N., Bergmann, S., Biffar, R., Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Braga, D., Buckley, B. M., Buyske, S., Campbell, H., Chambers, J. C., Collins, F. S., Curran, J. E., de Borst, G. J., de Craen, A. J. M., de Geus, E. J. C., Dedoussis, G., Delgado, G. E., den Ruijter, H. M., Eiriksdottir, G., Eriksson, A. L., Esko, T., Faul, J. D., Ford, I., Forrester, T., Gertow, K., Gigante, B., Glorioso, N., Gong, J., Grallert, H., Grammer, T. B., Grarup, N., Haitjema, S., Hallmans, G., Hamsten, A., Hansen, T., Harris, T. B., Hartman, C. A., Hassinen, M., Hastie, N. D., Heath, A. C., Hernandez, D., Hindorff, L., Hocking, L. J., Hollensted, M., Holmen, O. L., Homuth, G., Jan Hottenga, J., Huang, J., Hung, J., Hutri-Kähönen, N., Ingelsson, E., James, A. L., Jansson, J-O., Jarvelin, M-R., Jhun, M. A., Jørgensen, M. E., Juonala, M., Kähönen, M., Karlsson, M., Koistinen, H. A., Kolcic, I., Kolovou, G., Kooperberg, C., Krämer, B. K., Kuusisto, J., Kvaløy, K., Lakka, T. A., Langenberg, C., Launer, L. J., Leander, K., Lee, N. R., Lind, L., Lindgren, C. M., Linneberg, A., Lobbens, S., Loh, M., Lorentzon, M., Luben, R., Lubke, G., Ludolph-Donislawski, A., Lupoli, S., Madden, P. A. F., Männikkö, R., Marques-Vidal, P., Martin, N. G., McKenzie, C. A., McKnight, B., Mellström, D., Menni, C., Montgomery, G. W., Musk, A. B., Narisu, N., Nauck, M., Nolte, I. M., Oldehinkel, A. J., Olden, M., Ong, K. K., Padmanabhan, S., Peyser, P. A., Pisinger, C., Porteous, D. J., Raitakari, O. T., Rankinen, T., Rao, D. C., Rasmussen-Torvik, L. J., Rawal, R., Rice, T., Ridker, P. M., Rose, L. M., Bien, S. A., Rudan, I., Sanna, S., Sarzynski, M. A., Sattar, N., Savonen, K., Schlessinger, D., Scholtens, S., Schurmann, C., Scott, R. A., Sennblad, B., Siemelink, M. A., Silbernagel, G., Slagboom, P. E., Snieder, H., Staessen, J. A., Stott, D. J., Swertz, M. A., Swift, A. J., Taylor, K. D., Tayo, B. O., Thorand, B., Thuillier, D., Tuomilehto, J., Uitterlinden, A. G., Vandenput, L., Vohl, M-C., Völzke, H., Vonk, J. M., Waeber, G., Waldenberger, M., Westendorp, R. G. J., Wild, S., Willemsen, G., Wolffenbuttel, B. H. R., Wong, A., Wright, A. F., Zhao, W., Zillikens, M. C., Baldassarre, D., Balkau, B., Bandinelli, S., Böger, C. A., Boomsma, D. I., Bouchard, C., Bruinenberg, M., Chasman, D. I., Chen, Y-D., Chines, P. S., Cooper, R. S., Cucca, F., Cusi, D., Faire, U. D., Ferrucci, L., Franks, P. W., Froguel, P., Gordon-Larsen, P., Grabe, H-J., Gudnason, V., Haiman, C. A., Hayward, C., Hveem, K., Johnson, A. D., Wouter Jukema, J., Kardia, S. L. R., Kivimaki, M., Kooner, J. S., Kuh, D., Laakso, M., Lehtimäki, T., Marchand, L. L., März, W., McCarthy, M. I., Metspalu, A., Morris, A. P., Ohlsson, C., Palmer, L. J., Pasterkamp, G., Pedersen, O., Peters, A., Peters, U., Polasek, O., Psaty, B. M., Qi, L., Rauramaa, R., Smith, B. H., Sørensen, T. I. A., Strauch, K., Tiemeier, H., Tremoli, E., van der Harst, P., Vestergaard, H., Vollenweider, P., Wareham, N. J., Weir, D. R., Whitfield, J. B., Wilson, J. F., Tyrrell, J., Frayling, T. M., Barroso, I., Boehnke, M., Deloukas, P., Fox, C. S., Hirschhorn, J. N., Hunter, D. J., Spector, T. D., Strachan, D. P., van Duijn, C. M., Heid, I. M., Mohlke, K. L., Marchini, J., Loos, R. J. F., Kilpeläinen, T. O., Liu, C-T., Borecki, I. B., North, K. E. & Cupples, L. A., 26 Apr 2017, In: Nature Communications. 8, p. 1-19 19 p., 14977.

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  • Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

    Graff, M., Scott, R. A., Justice, A. E., Young, K. L., Feitosa, M. F., Barata, L., Winkler, T. W., Chu, A. Y., Mahajan, A., Hadley, D., Xue, L., Workalemahu, T., Heard-Costa, N. L., den Hoed, M., Ahluwalia, T. S., Qi, Q., Ngwa, J. S., Renström, F., Quaye, L., Eicher, J. D., & 31 othersHayes, J. E., Cornelis, M., Kutalik, Z., Lim, E., Luan, J., Huffman, J. E., Zhang, W., Zhao, W., Griffin, P. J., Haller, T., Ahmad, S., Marques-Vidal, P. M., Bien, S., Yengo, L., Teumer, A., Smith, A. V., Kumari, M., Harder, M. N., Justesen, J. M., Kleber, M. E., Hollensted, M., Lohman, K., Rivera, N. V., Whitfield, J. B., Zhao, J. H., Stringham, H. M., Lyytikäinen, L-P., Huppertz, C., Willemsen, G., Hocking, L. J. & CHARGE Consortium, 27 Apr 2017, In: PLoS Genetics. 13, 4, p. 1-26 26 p., e1006528.

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  • Genome-wide prediction of stop codon readthrough during translation in the yeast Saccharomyces cerevisiae

    Williams, I. A., Richardson, J. P., Starkey, A. & Stansfield, I., Dec 2004, In: Nucleic Acids Research. 32, 22, p. 6605-6616 11 p.

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    54 Citations (Scopus)

  • Genome-wide reconstruction of rediploidization following autopolyploidization across one hundred million years of salmonid evolution

    Gundappa, M. K., To, T-H., Grønvold, L., Martin, S. A. M., Lien, S., Geist, J., Hazlerigg, D., Sandve, S. R. & Macqueen, D. J., 1 Jan 2022, In: Molecular Biology and Evolution. 39, 1, 18 p., msab310.

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  • Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder

    Zeng, Y., Navarro, P., Shirali, M., Howard, D. M., Adams, M. J., Hall, L. S., Clarke, T. K., Thomson, P. A., Smith, B. H., Murray, A., Padmanabhan, S., Hayward, C., Boutin, T., MacIntyre, D. J., Lewis, C. M., Wray, N. R., Mehta, D., Penninx, B. W. J. H., Milaneschi, Y., Baune, B. T., & 20 othersAir, T., Hottenga, J. J., Mbarek, H., Castelao, E., Pistis, G., Schulze, T. G., Streit, F., Forstner, A. J., Byrne, E. M., Martin, N. G., Breen, G., Müller-Myhsok, B., Lucae, S., Kloiber, S., Domenici, E., Deary, I. J., Porteous, D. J., Haley, C. S., McIntosh, A. M. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Sep 2017, In: Biological Psychiatry. 82, 5, p. 312-321 10 p.

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  • Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35

    Hocking, L., Herbert, C. A., Nicholls, R. K., Williams, F., Bennett, S. T., Cundy, T., Nicholson, G. C., Wuyts, W., Van Hul, W. & Ralston, S., Nov 2001, In: American Journal of Human Genetics. 69, 5, p. 1055-1061 6 p.

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  • Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability

    Morgan, M. D., Pairo-Castineira, E., Rawlik, K., Canela-Xandri, O., Rees, J., Sims, D., Tenesa, A. & Jackson, I. J., 10 Dec 2018, In: Nature Communications. 9, 5271.

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  • Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis

    Afouda, B. A., Lynch, A. T., De Paiva Alves, E. & Hoppler, S., 1 Feb 2018, In: Developmental Biology. 434, 1, p. 108-120 13 p.

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  • Genome-wide transcriptomics analysis of genes regulated by GATA4, 5 and 6 during cardiomyogenesis in Xenopus laevis

    Afouda, B. A., Lynch, A. T., De Paiva Alves, E. & Hoppler, S., Apr 2018, In: Data in brief. 17, p. 559-563 5 p.

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  • Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development

    Fernandes, J. M. O., Macqueen, D. J., Lee, H-T. & Johnston, I. A., Apr 2008, In: Genomics. 91, 4, p. 315-325 11 p.

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  • Genómica funcional en embriones y ovocitos humanos individuales

    Translated title of the contribution: Functional genomics in single embryo and human oocytesPina Aguilar, R. E., 29 Mar 2007, In: Gaceta Medica de Mexico. 143, 1, p. 89-91 3 p.

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  • Genomic Analyses of Bifidobacterium moukalabense Reveal Adaptations to Frugivore/Folivore Feeding Behavior

    Segawa, T., Fukuchi, S., Bodington, D., Tsuchida, S., Mbehang Nguema, P. P., Mori, H. & Ushida, K., 4 Apr 2019, In: Microorganisms. 7, 4, 13 p.

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  • Genomic Analyses of Pre-European Conquest Human Remains from the Canary Islands Reveal Close Affinity to Modern North Africans

    Rodríguez-Varela, R., Günther, T., Krzewińska, M., Storå, J., Gillingwater, T. H., MacCallum, M., Arsuaga, J. L., Dobney, K., Valdiosera, C., Jakobsson, M., Götherström, A. & Girdland-Flink, L., 6 Nov 2017, In: Current Biology. 27, 21, p. 3396-3402 6 p.

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  • Genomic analysis of variation in hindlimb musculature of mice from the C57BL/6J and DBA/2J lineage

    Lionikas, A., Carlborg, Ö., Lu, L., Peirce, J. L., Williams, R. W., Yu, F., Vogler, G. P., McClearn, G. E. & Blizard, D. A., May 2010, In: Journal of Heredity. 101, 3, p. 360-367 8 p.

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  • Genomic and microarray analysis of aromatics degradation in Geobacter metallireducens and comparison to a Geobacter isolate from a contaminated field site

    Butler, J. E., He, Q., Nevin, K. P., He, Z., Zhou, J. & Lovley, D. R., 19 Jun 2007, In: BMC Genomics. 8, 180.

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  • Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

    Khatib, T., Marini, P., Nunna, S., Chisholm, D. R., Whiting, A., Redfern, C., Greig, I. R. & McCaffery, P., 2 May 2019, In: Cell Communication and Signaling. 17, 16 p., 40.

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  • Genomic basis of deep-water adaptation in Arctic Charr (Salvelinus alpinus) morphs

    Kess, T., Dempson, J. B., Lehnert, S. J., Layton, K., Einfeldt, A., Bentzen, P., Salisbury, S. J., Messmer, A., Duffy, S., Ruzzante, D. E., Nugent, C. M., Ferguson, M. M., Leong, J. S., Koop, B. F., O'Connell, M. F. & Bradbury, I. R., 1 Sep 2021, In: Molecular Ecology. 30, 18, p. 4415-4432 18 p.

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  • Genomic changes identified by comparative genomic hybridisation in docetaxel-resistant breast cancer cell lines

    McDonald, S., Stevenson, D. A. J., Moir, S., Hutcheon, A. W., Haites, N. E., Heys, S. D. & Schofield, A. C., 1 May 2005, In: European Journal of Cancer. 41, 7, p. 1086-94 9 p.

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  • Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris

    Rhodes, J., Abdolrasouli, A., Farrer, R. A., Cuomo, C. A., Aanensen, D. M., Armstrong-James, D., Fisher, M. C. & Schelenz, S., 29 Mar 2018, In: Emerging Microbes and Infections. 7, 43.

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  • Genomic evidence of past and future climate-linked loss in a migratory Arctic fish

    Layton, K., Snelgrove, P., Dempson, J. B., Kess, T., Lehnert, S., Bentzen, P., Duffy, S., Messmer, A., Stanley, R., DiBacco, C., Salisbury, S., Ruzzante, D., Nugent, C., Ferguson, M., Leong, J., Koop, B. & Bradbury, I., 1 Feb 2021, In: Nature Climate Change. 11, 2, p. 158-165 8 p.

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