Find Research Outputs

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Marcel Jaspars
2020

A cell-based assay system for activators of the environmental cell stress response

Harbottle, J. A., Petrie, L., Ruhe, M., Houssen, W. E., Jaspars, M. & Kolb, A. F., 1 Mar 2020, In : Analytical Biochemistry. 592, 113583.

Research output: Contribution to journalArticle

Downsizing Class II Lasso Peptides: Genome Mining-Guided Isolation of Huascopeptin Containing the First Gly1-Asp7 Macrocycle

Cortés-Albayay, C., Jarmusch, S. A., Trusch, F., Ebel, R., Andrews, B. A., Jaspars, M. & Asenjo, J. A., 7 Feb 2020, In : Journal of Organic Chemistry. 85, 3, p. 1661-1667 7 p.

Research output: Contribution to journalArticle

Structure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptide

Idress, M., Milne, B. F., Thompson, G. S., Trembleau, L., Jaspars, M. & Houssen, W. E., 19 Feb 2020, In : Molecules. 25, 4, 922.

Research output: Contribution to journalArticle

Open Access
File

Whole Genome Sequence of Dermacoccus abyssi MT1.1 Isolated from the Challenger Deep of the Mariana Trench Reveals Phenazine Biosynthesis Locus and Environmental Adaptation Factors

Abdel-Mageed, W. M., Juhasz, B., Lehri, B., Alqahtani, A. S., Nouioui, I., Pech-Puch, D., Tabudravu, J. N., Goodfellow, M., Rodríguez, J., Jaspars, M. & Karlyshev, A. V., 25 Feb 2020, In : Marine Drugs. 18, 3, 18 p., 131.

Research output: Contribution to journalArticle

Open Access
File
2019

Amphidinol 22, a New Cytotoxic and Antifungal Amphidinol from the Dinoflagellate Amphidinium carterae

Martínez, K. A., Lauritano, C., Druka, D., Romano, G., Grohmann, T., Jaspars, M., Martín, J., Díaz, C., Cautain, B., de la Cruz, M., Ianora, A. & Reyes, F., 27 Jun 2019, In : Marine Drugs. 17, 7, 385.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
1 Downloads (Pure)

Heterologous expression of a cryptic gene cluster from Streptomyces leeuwenhoekii C34T yields a novel lasso peptide, leepeptin

Gomez-Escribano, J. P., Castro, J. F., Razmilic, V., Jarmusch, S. A., Saalbach, G., Ebel, R., Jaspars, M., Andrews, B., Asenjo, J. A. & Bibb, M. J., 1 Dec 2019, In : Applied and Environmental Microbiology. 85, 23, 13 p., e01752-19.

Research output: Contribution to journalArticle

Open Access
File

Inclusive innovation: Enhancing global participation in and benefit sharing linked to the utilization of marine genetic resources from areas beyond national jurisdiction

Collins, J. E., Harden-Davies, H., Jaspars, M., Thiele, T., Vanagt, T. & Huys, I., Nov 2019, In : Marine Policy. 109, 10 p., 103696.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

LC-HRMS-Database Screening Metrics for Rapid Prioritization of Samples to Accelerate the Discovery of Structurally New Natural Products

Tabudravu, J. N., Pellissier, L., Smith, A. J., Subko, K., Autréau, C., Feussner, K., Hardy, D., Butler, D., Kidd, R., Milton, E. J., Deng, H., Ebel, R., Salonna, M., Gissi, C., Montesanto, F., Kelly, S. M., Milne, B. F., Cimpan, G. & Jaspars, M., 2019, In : Journal of Natural Products. 82, 2, p. 211-220 10 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)

Legonoxamines A-B, two new hydroxamate siderophores from the soil bacterium, Streptomyces sp. MA37

Maglangit, F., Tong, M. H., Jaspars, M., Kyeremeh, K. & Deng, H., 3 Jan 2019, In : Tetrahedron Letters. 60, 1, p. 75-79 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Paenidigyamycin g: 1-acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium

Tetevi, G. M., Kwain, S., Mensah, T., Camas, A. S., Camas, M., Dofuor, A. K., Azerigyik, F. A., Oluwabusola, E., Deng, H., Jaspars, M. & Kyeremeh, K., 21 Nov 2019, In : MolBank. 2019, 4, 9 p., M1094.

Research output: Contribution to journalComment/debate

Open Access
File

Simplified immunosuppressive and neuroprotective agents based on gracilin A

Abbasov, M. E., Alvariño, R., Chaheine, C. M., Alonso, E., Sánchez, J. A., Conner, M. L., Alfonso, A., Jaspars, M., Botana, L. M. & Romo, D., Apr 2019, In : Nature Chemistry. 11, p. 342-350 9 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Uncovering the potential of novel micromonosporae isolated from an extreme hyper-arid Atacama Desert soil

Carro, L., Castro, J. F., Razmilic, V., Nouioui, I., Pan, C., Igual, J. M., Jaspars, M., Goodfellow, M., Bull, A. T., Asenjo, J. A. & Klenk, H-P., 18 Mar 2019, In : Scientific Reports. 9, 4678.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
4 Downloads (Pure)

α-D-glucopyranosyl-(1→2)-[6-O-(L-tryptophanyl)-β-D-fructofuranoside]

Kyeremeh, K., Kwain, S., Tetevi, G. M., Camas, A. S., Camas, M., Dofuor, A. K., Deng, H. & Jaspars, M., 16 Jun 2019, In : MolBank. 2019, 2, 11 p., M1066.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)
2018

Antibiotics from Deep-Sea Microorganisms: Current Discoveries and Perspectives

Tortorella, E., Tedesco, P., Palma Esposito, F., January, G. G., Fani, R., Jaspars, M. & de Pascale, D., 29 Sep 2018, In : Marine Drugs. 16, 10, 16 p., 355.

Research output: Contribution to journalReview article

Open Access
File
18 Citations (Scopus)
8 Downloads (Pure)

Asenjonamides A-C, antibacterial metabolites isolated from Streptomyces asenjonii strain KNN 42.f from an extreme-hyper arid Atacama Desert soil

Abdelkader, M. S. A., Philippon, T., Asenjo, J. A., Bull, A. T., Goodfellow, M., Ebel, R., Jaspars, M. & Rateb, M. E., 2018, In : The Journal of antibiotics. 71, p. 425-431 7 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
7 Downloads (Pure)

Hyphenated LC-ICP-MS/ESI-MS identification of halogenated metabolites in South African marine ascidian extracts

Bromley, C. L., Raab, A., Parker-Nance, S., Beukes, D. R., Jaspars, M. & Davies-Coleman, M. T., 31 Dec 2018, In : South African Journal of Chemistry. 71, 1, p. 111-117 7 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Mare Geneticum: Balancing Governance of Marine Genetic Resources in International Waters

Broggiato, A., Vanagt, T., Lallier, L. E., Jaspars, M., Burton, G. & Muyldermans, D., Mar 2018, In : International Journal of Marine and Coastal Law. 33, 1, p. 3-33 31 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
15 Downloads (Pure)

Natural product diversity of actinobacteria in the Atacama Desert

Rateb, M. E., Ebel, R. & Jaspars, M., Aug 2018, In : Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology. 111, 8, p. 1467-1477 11 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
7 Downloads (Pure)

Paenidigyamycin A, Potent Antiparasitic Imidazole Alkaloid from the Ghanaian Paenibacillus sp. DE2SH

Osei, E., Kwain, S., Mawuli, G. T., Anang, A. K., Owusu, K. B-A., Camas, M., Camas, A. S., Ohashi, M., Alexandru-Crivac, C-N., Deng, H., Jaspars, M. & Kyeremeh, K., 24 Dec 2018, In : Marine Drugs. 17, 1, 9.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
5 Downloads (Pure)

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

Dambuza, I. M., Drake, T., Chapuis, A., Zhou, X., Correia, J., Taylor-Smith, L., Legrave, N., Rasmussen, T., Fisher, M. C., Bicanic, T., Harrison, T. S., Jaspars, M., May, R. C., Brown, G. D., Yuecel, R., MacCallum, D. M. & Ballou, E., 18 May 2018, In : PLoS Pathogens. 14, 5, p. 1-28 28 p., e1006978.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
8 Downloads (Pure)

Zebrafish-Based Discovery of Antiseizure Compounds from the Red Sea: Pseurotin A2 and Azaspirofuran A

Copmans, D., Rateb, M., Tabudravu, J. N., Pérez-Bonilla, M., Dirkx, N., Vallorani, R., Diaz, C., Pérez Del Palacio, J., Smith, A. J., Ebel, R., Reyes, F., Jaspars, M. & de Witte, P. A. M., 2018, In : ACS Chemical Neuroscience. 9, 7, p. 1652-1662 11 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
4 Downloads (Pure)
2017

A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize

Booth, J., Alexandru-Crivac, C-N., Rickaby, K. A., Nneoyiegbe, A. F., Umeobika, U., McEwan, A. R., Trembleau, L., Jaspars, M., Houssen, W. E. & Shalashilin, D. V., 18 May 2017, In : The Journal of Physical Chemistry Letters. 8, 10, p. 2310-2315 6 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
10 Downloads (Pure)

Bypassing the proline/thiazoline requirement of the macrocyclase PatG

Oueis, E., Stevenson, H., Jaspars, M., Westwood, N. J. & Naismith, J. H., 25 Nov 2017, In : Chemical Communications. 53, 91, p. 12274-12277 4 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
4 Downloads (Pure)

Cyclic peptide production using a macrocyclase with enhanced substrate promiscuity and relaxed recognition determinants

Alexandru-Crivac, C. N., Umeobika, C., Leikoski, N., Jokela, J., Rickaby, K., Grilo, A. M., Sjo, P., Plowright, A. T., Idress, M., Siebs, E., Nneoyi-Egbe, A., Wahlsten, M., Sivonen, K., Jaspars, M., Trembleau, L., Fewer, D. P. & Houssen Ibrahim, W. E., 4 Oct 2017, In : Chemical Communications. 53, 77, p. 10656-10659 4 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
10 Downloads (Pure)

Cyclic Peptides – A Look to the Future

Idress, M., Alexandru-Crivac, C. N., Jaspars, M., Trembleau, L. A. C., Houssen Ibrahim, W. E-S. M., Rickaby, K. A. & Dalponte, L., 15 Dec 2017, Cyclic Peptides: From Bioorganic Synthesis to Applications . Koehnke, J., Naismith, J. & van der Donk, W. A. (eds.). UK: Royal Society of Chemistry (Great Britain) , p. 340-373 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation

Wakefield, J., Hassan, H. M., Jaspars, M., Ebel, R. & Rateb, M. E., 11 Jul 2017, In : Frontiers in Microbiology. 8, p. 1-10 10 p., 1284.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
8 Downloads (Pure)

Increased Biological Activity of Aneurinibacillus migulanus Strains Correlates with the Production of New Gramicidin Secondary Metabolites

Alenezi, F. N., Rekik, I., Bouket, A. C., Luptakova, L., Rateb, M. E., Weitz, H. J., Jaspars, M., Woodward, S. & Belbahri, L., 7 Apr 2017, In : Frontiers in Microbiology. 8, p. 1-11 11 p., 517.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
5 Downloads (Pure)

Isolation and anti-HIV-1 integrase activity of lentzeosides A-F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil

Wichner, D., Idris, H., Houssen, W. E., McEwan, A. R., Bull, A. T., Asenjo, J. A., Goodfellow, M., Jaspars, M., Ebel, R. & Rateb, M. E., Apr 2017, In : The Journal of antibiotics. 70, p. 448-453 6 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
5 Downloads (Pure)

Pseudochelin A, a siderophore of Pseudoalteromonas piscicida S2040

Sonnenschein, E. C., Stierhof, M., Goralczyk, S., Vabre, F. M., Pellissier, L., Hanssen, K. Ø., de la Cruz, M., Díaz, C., de Witte, P., Copmans, D., Andersen, J. H., Hansen, E., Kristoffersen, V., Tormo, J. R., Ebel, R., Milne, B. F., Deng, H., Gram, L., Jaspars, M. & Tabudravu, J. N., 4 May 2017, In : Tetrahedron. 73, 18, p. 2633-2637 5 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
7 Downloads (Pure)

Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization

Oueis, E., Nardone, B., Jaspars, M., Westwood, N. J. & Naismith, J. H., 1 Feb 2017, In : ChemistryOpen. 6, 1, p. 11-14 4 p.

Research output: Contribution to journalComment/debate

Open Access
File
13 Citations (Scopus)
6 Downloads (Pure)

Targeted Dereplication of Microbial Natural Products by High-Resolution MS and Predicted LC Retention Time

Chervin, J., Stierhof, M., Tong, M. H., Peace, D., Hansen, K. Ø., Urgast, D. S., Andersen, J. H., Yu, Y., Ebel, R., Kyeremeh, K., Paget, V., Cimpan, G., Wyk, A. V., Deng, H., Jaspars, M. & Tabudravu, J. N., 26 May 2017, In : Journal of Natural Products. 80, 5, p. 1370-1377 8 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
4 Downloads (Pure)
2016

Accurate quantification of modified cyclic peptides without the need for authentic standards

Adaba, R. I., Mann, G., Raab, A., Houssen, W. E., McEwan, A. R., Thomas, L., Tabudravu, J., Naismith, J. H. & Jaspars, M., 29 Dec 2016, In : Tetrahedron. 72, 52, p. 8603-8609 7 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
6 Downloads (Pure)

Antimicrobial Activity of Monoramnholipids Produced by Bacterial Strains Isolated from the Ross Sea (Antarctica)

Tedesco, P., Maida, I., Palma Esposito, F., Tortorella, E., Subko, K., Ezeofor, C. C., Zhang, Y., Tabudravu, J., Jaspars, M., Fani, R. & de Pascale, D., 26 Apr 2016, In : Marine Drugs. 14, 5, p. 1-14 14 p., 83.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
7 Downloads (Pure)

A Unique Tryptophan C-Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway

Parajuli, A., Kwak, D. H., Dalponte, L., Leikoski, N., Galica, T., Umeobika, U., Trembleau, L., Bent, A., Sivonen, K., Wahlsten, M., Wang, H., Rizzi, E., De Bellis, G., Naismith, J., Jaspars, M., Liu, X., Houssen, W. & Fewer, D. P., 7 Mar 2016, In : Angewandte Chemie. 128, 11, p. 3660-3663 4 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
8 Downloads (Pure)

Enzymatic Macrocyclization of 1,2,3-Triazole Peptide Mimetics

Oueis, E., Jaspars, M., Westwood, N. J. & Naismith, J. H., 4 May 2016, In : Angewandte Chemie International Edition. 55, 19, p. 5842-5845 4 p.

Research output: Contribution to journalArticle

Open Access
File
27 Citations (Scopus)
7 Downloads (Pure)

Evaluation of the Antioxidant Activity of the Marine Pyrroloiminoquinone Makaluvamines

Alonso, E., Alvariño, R., Leirós, M., Tabudravu, J. N., Feussner, K., Dam, M. A., Rateb, M. E., Jaspars, M. & Botana, L. M., 27 Oct 2016, In : Marine Drugs. 14, 11, 197.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
6 Downloads (Pure)

Harpulliasides A and B: Two new benzeneacetic acid derivatives from Harpullia pendula

Abdelkader, M. S. A., Rateb, M., Mohamed, G. A. & Jaspars, M., Mar 2016, In : Phytochemistry letters. 15, p. 131-135 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Identification of Spongionella compounds as cyclosporine A mimics

Sánchez, J. A., Alfonso, A., Leirós, M., Alonso, E., Rateb, M. E., Jaspars, M., Houssen, W. E., Ebel, R., Tabudravu, J. & Botana, L. M., May 2016, In : Pharmacological Research. 107, p. 407-414 8 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
5 Downloads (Pure)

Inside Cover: The Catalytic Mechanism of the Marine-Derived Macrocyclase PatGmac (Chem. Eur. J. 37/2016)

Brás, N. F., Ferreira, P., Calixto, A. R., Jaspars, M., Houssen, W., Naismith, J. H., Fernandes, P. A. & Ramos, M. J., 5 Sep 2016, In : Chemistry : a European Journal. 22, 37, p. 12946 1 p.

Research output: Contribution to journalArticle

New cytotoxic callipeltins from the Solomon Island marine sponge Asteropus sp.

Stierhof, M., Hansen, K. Ø., Sharma, M., Feussner, K., Subko, K., Díaz-Rullo, F. F., Isaksson, J., Pérez-Victoria, I., Clarke, D., Hansen, E., Jaspars, M. & Tabudravu, J. N., 3 Nov 2016, In : Tetrahedron. 72, 44, p. 6929-6934 6 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
6 Downloads (Pure)

Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation

Sánchez, J. A., Alfonso, A., Rodriguez, I., Alonso, E., Cifuentes, J. M., Bermudez, R., Rateb, M. E., Jaspars, M., Houssen, W. E., Ebel, R., Tabudravu, J. & Botana, L. M., 24 Oct 2016, In : Frontiers in Immunology. 7, 452.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
5 Downloads (Pure)

Strain-level diversity of secondary metabolism in the biocontrol species Aneurinibacillus migulanus

Alenezi, F. N. H. H. K., Rekik, I., Belka, M., Ibrahim, A. F., Luptakova, L., Jaspars, M., Woodward, S. & Belbahri, L., Jan 2016, In : Microbiological Research. 182, p. 116-124 9 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD

Bent, A. F., Mann, G., Houssen, W. E., Mykhaylyk, V., Duman, R., Thomas, L., Jaspars, M., Wagner, A. & Naismith, J. H., 1 Nov 2016, In : Acta Crystallographica Section D: Structural Biology. 72, 11, p. 1174-1180 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
7 Downloads (Pure)

The Catalytic Mechanism of the Marine-Derived Macrocyclase, PATGmac

Bras, N. F., Ferreira, P., Calixto, A. R., Jaspars, M., Houssen Ibrahim, W. E-S. M., Naismith, J. H., Fernandes, P. A. & Ramos, M. J., 5 Sep 2016, In : Chemistry : a European Journal. 22, 37, p. 13089-13097 9 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
5 Downloads (Pure)

The marine biodiscovery pipeline and ocean medicines of tomorrow

Jaspars, M., De Pascale, D., Andersen, J. H., Reyes, F., Crawford, A. D. & Ianora, A., Feb 2016, In : Journal of the Marine Biological Association of the United Kingdom. 96, 1, p. 151-158 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)