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Publication Year

  • 2020
  • 2019
  • 2018
  • 2016

Author

  • Iain Greig
2020

A Novel Allosteric Modulator of the Cannabinoid CB1 Receptor Ameliorates Hyperdopaminergia Endophenotypes in Rodent Models

Mielnik, C. A., Sugamori, K. S., Finlay, D. B., Thorpe, H. H. A., Schapira, M., Sivananthan, N., Li, C. K., lam, V. M., Harrington, S., Abdelrahman, M. H., Trembleau, L. A., Burnham, W. M., Khokhar, J. Y., Salahpour, A., Ramsey, A. J., Glass, M., Greig, I. & Ross, R. A., 10 Aug 2020, (Accepted/In press) In : Neuropsychopharmacology.

Research output: Contribution to journalArticle

Evidence that cannabinoid CB1 receptors regulate intraocular pressure via two opposing mechanisms

Miller, S., Daily, L., Ploss, M., Greig, I., Ross, R., Rayana, N. P., Dai, J., Sugali, C. K., Mao, W. & Straiker, A., 14 Sep 2020, In : Experimental Eye Research. 200, 6 p., 108241.

Research output: Contribution to journalArticle

2019

Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids

Khatib, T., Marini, P., Nunna, S., Chisholm, D. R., Whiting, A., Redfern, C., Greig, I. R. & McCaffery, P., 2 May 2019, In : Cell Communication and Signaling. 17, 16 p., 40.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
8 Downloads (Pure)

Synthetic Retinoids for Use in RAR Mediated Conditions

Whiting, A., Chisholm, D., Valentine, R., Greig, I. R., McCaffery, P. J. A. & Alkhatib, T., 18 Apr 2019, IPC No. C07C 63/66, A61K 31/192, A61K 31/203, A61P 25/28, C07D 209/82, C07D 215/06, European Patent Office, Patent No. WO2017174999, Priority date 6 Apr 2017, Priority No. 2017050977

Research output: Patent

The Trifluoromethyl Group as a Bioisosteric Replacement of the Aliphatic Nitro Group in CB1 Receptor Positive Allosteric Modulators (PAMs)

Tseng, C-C., Baillie, G., Donvito, G., Mustafa, M. A., Juola, S. E., Zanato, C., Massarenti, C., Dall'angelo, S., Harrison, W. T. A., Lichtman, A. H., Ross, R. A., Zanda, M. & Greig, I. R., 2019, In : Journal of Medicinal Chemistry. 62, 10, p. 5049-5062 14 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
3 Downloads (Pure)
2018

Effects of glycol-split low molecular weight heparin on placental, endothelial, and anti-inflammatory pathways relevant to preeclampsia

Wat, J. M., Hawrylyshyn, K., Baczyk, D., Greig, I. R. & Kingdom, J. C., 1 Nov 2018, In : Biology of Reproduction. 99, 5, p. 1082-1090 9 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
10 Downloads (Pure)

Enantiomer-specific positive allosteric modulation of CB1 signaling in autaptic hippocampal neurons

Mitjavila, J., Yin, D., Kulkarni, P. M., Zanato, C., Thakur, G. A., Ross, R., Greig, I., Mackie, K. & Straiker, A., Mar 2018, In : Pharmacological Research. 129, p. 475-481 7 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
9 Downloads (Pure)

Small Molecule Inhibitors of Metabolic Enzymes Repurposed as a New Class of Anthelmintics

Tyagi, R., Maddirala, A. R., Elfawal, M., Fischer, C., Bulman, C. A., Rosa, B. A., Gao, X., Chugani, R., Zhou, M., Helander, J., Brindley, P. J., Tseng, C-C., Greig, I. R., Sakanari, J., Wildman, S. A., Aroian, R., Janetka, J. W. & Mitreva, M., 13 Jul 2018, In : ACS Infectious Diseases. 4, 7, p. 1130–1145 16 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
6 Downloads (Pure)
2016

Asymmetric Synthesis and Absolute Configuration of (+)- and (–)-Perhexiline

Tseng, C-C., Greig, I. R., Harrison, W. T. A. & Zanda, M., Jan 2016, In : Synthesis. 48, 01, p. 73-78 6 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
7 Downloads (Pure)

Development of indole sulfonamides as cannabinoid receptor negative allosteric modulators

Greig, I. R., Baillie, G. L., Abdelrahman, M., Trembleau, L. & Ross, R. A., 15 Sep 2016, In : Bioorganic & Medicinal Chemistry Letters. 26, 18, p. 4403-4407 5 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
8 Downloads (Pure)