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  • 2020
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  • Andrew Porter
2020

Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature

Leach, A., Smyth, P., Ferguson, L., Steven, J., Greene, M. K., Branco, C. M., McCann, A. P., Porter, A., Barelle, C. J. & Scott, C. J., 21 Jul 2020, In : Nanoscale. 12, 27, p. 14751-14763 13 p.

Research output: Contribution to journalArticle

Open Access
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1 Downloads (Pure)
Open Access
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3 Downloads (Pure)
2019
Open Access
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3 Citations (Scopus)
7 Downloads (Pure)

Mitochondrial dysfunction is a key determinant of the rare disease lymphangioleiomyomatosis and provides a novel therapeutic target

Abdelwahab, E. M. M., Pal, S., Kvell, K., Sarosi, V., Bai, P., Rue, R., Krymskaya, V., McPhail, D., Porter, A. & Pongracz, J. E., 2019, In : Oncogene. 38, p. 3093-3101 9 p.

Research output: Contribution to journalArticle

Open Access
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6 Downloads (Pure)

Oriented attachment of VNAR proteins, Q2 via site-selective modification, on PLGA–PEG nanoparticles enhances nanoconjugate performance

Nogueira, J. C. F., Greene, M. K., Richards, D. A., Furby, A. O., Steven, J., Porter, A., Barelle, C., Scott, C. J. & Chudasama, V., 7 Jul 2019, In : Chemical Communications. 55, 53, p. 7671-7674 4 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
7 Downloads (Pure)

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

Pepple, K. L., Wilson, L., Van Gelder, R. N., Kovaleva, M., Ubah, O. C., Steven, J., Barelle, C. J. & Porter, A., Sep 2019, In : Translational vision science & technology. 8, 5, 13 p., 11.

Research output: Contribution to journalArticle

Open Access
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5 Downloads (Pure)
2017

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

Steven, J., Müller, M. R., Carvalho, M. F., Ubah, O. C., Kovaleva, M., Donohoe, G., Baddeley, T., Cornock, D., Saunders, K., Porter, A. J. & Barelle, C. J., 23 Oct 2017, In : Frontiers in Immunology. 8, 1361.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
6 Downloads (Pure)

Novel, anti-hTNF-α VNAR formats with enhanced neutralising potency and multi-functionality, generated for therapeutic development

Ubah, O. C., Steven, J., Kovaleva, M., Ferguson, L., Barelle, C., Porter, A. J. R. & Barelle, C. J., 22 Dec 2017, In : Frontiers in Immunology. 8, p. 1-13 13 p., 1780.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
9 Downloads (Pure)