A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up

R. P. Croft, Peter Gregory Nicholls, E. W. Steyerberg, J. H. Richardus, S. G. Withington, William Cairns Stewart Smith

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical prediction rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NE occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.

Original languageEnglish
Pages (from-to)35-41
Number of pages6
JournalLeprosy Review
Volume74
Issue number1
Publication statusPublished - Mar 2003

Keywords

  • PROSPECTIVE COHORT
  • BANGLADESH
  • DAMAGE
  • MODELS

Cite this

Croft, R. P., Nicholls, P. G., Steyerberg, E. W., Richardus, J. H., Withington, S. G., & Smith, W. C. S. (2003). A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up. Leprosy Review, 74(1), 35-41.

A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up. / Croft, R. P.; Nicholls, Peter Gregory; Steyerberg, E. W.; Richardus, J. H.; Withington, S. G.; Smith, William Cairns Stewart.

In: Leprosy Review, Vol. 74, No. 1, 03.2003, p. 35-41.

Research output: Contribution to journalArticle

Croft, RP, Nicholls, PG, Steyerberg, EW, Richardus, JH, Withington, SG & Smith, WCS 2003, 'A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up', Leprosy Review, vol. 74, no. 1, pp. 35-41.
Croft RP, Nicholls PG, Steyerberg EW, Richardus JH, Withington SG, Smith WCS. A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up. Leprosy Review. 2003 Mar;74(1):35-41.
Croft, R. P. ; Nicholls, Peter Gregory ; Steyerberg, E. W. ; Richardus, J. H. ; Withington, S. G. ; Smith, William Cairns Stewart. / A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up. In: Leprosy Review. 2003 ; Vol. 74, No. 1. pp. 35-41.
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