Abstract
Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical prediction rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NE occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.
| Original language | English |
|---|---|
| Pages (from-to) | 35-41 |
| Number of pages | 6 |
| Journal | Leprosy Review |
| Volume | 74 |
| Issue number | 1 |
| Publication status | Published - Mar 2003 |
Keywords
- PROSPECTIVE COHORT
- BANGLADESH
- DAMAGE
- MODELS
Cite this
A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up. / Croft, R. P.; Nicholls, Peter Gregory; Steyerberg, E. W.; Richardus, J. H.; Withington, S. G.; Smith, William Cairns Stewart.
In: Leprosy Review, Vol. 74, No. 1, 03.2003, p. 35-41.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A clinical prediction rule for nerve function impairment in leprosy patients-revisited after 5 years of follow-up
AU - Croft, R. P.
AU - Nicholls, Peter Gregory
AU - Steyerberg, E. W.
AU - Richardus, J. H.
AU - Withington, S. G.
AU - Smith, William Cairns Stewart
PY - 2003/3
Y1 - 2003/3
N2 - Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical prediction rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NE occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.
AB - Nerve function impairment (NFI) commonly occurs during or after chemotherapy in leprosy. We previously described a clinical prediction rule to estimate the risk of NFI occurring within 2 years of diagnosis, based on 2510 patients who are followed up in the Bangladesh Acute Nerve Damage Study (BANDS). This prediction rule assigns new leprosy patients to one of three risk groups based on leprosy group and the presence or absence of NFI at registration. Updated data with up to 5 years of follow-up showed that 95% of all NE occurred within 2 years. This study confirms the validity of the rule and supports the conclusion that there is little value for the detection of NFI in extending follow-up beyond 2 years.
KW - PROSPECTIVE COHORT
KW - BANGLADESH
KW - DAMAGE
KW - MODELS
M3 - Article
VL - 74
SP - 35
EP - 41
JO - Leprosy Review
JF - Leprosy Review
SN - 0305-7518
IS - 1
ER -