A combined TDDA-PVC pH and reference electrode for use in the upper small intestine

G T McEwan, M L Lucas, M Denvir, M Raj, K E McColl, R I Russell, V I Mathan

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Incorporation of a ligand into polyvinylchloride allows the production of ion selective electrodes that are soft-bodied and disposable. With features make them especially suitable for clinical, particularly gastroenterological, investigations. We report here on the construction of a combined reference and pH electrode suitable for use at jejunal biopsy. With this type of pH electrode, the pH of the mucosal surface of the jejunum in UK and in Indian subjects, without evidence of upper gastrointestinal disease, was about pH 6.0. This was almost identical to previous values measured using a separate reference electrode. Both the polymer electrode and a suitable data logger can be conveniently produced in the laboratory and compare favourably with commercially available systems, provided the range of pH likely to be encountered is within the operating range of the incorporated ligand.
Original languageEnglish
Pages (from-to)16-20
Number of pages5
JournalJournal of Medical Engineering & Technology
Volume14
Issue number1
Publication statusPublished - 1990

Fingerprint

Polyvinyl chlorides
Electrodes
Ligands
Ion selective electrodes
Biopsy
Polymers

Keywords

  • Amines
  • Biopsy
  • Celiac Disease
  • Electrodes
  • Equipment Design
  • Humans
  • Hydrogen-Ion Concentration
  • Intestinal Mucosa
  • Jejunum
  • Ligands
  • Polyvinyl Chloride
  • Reference Values

Cite this

McEwan, G. T., Lucas, M. L., Denvir, M., Raj, M., McColl, K. E., Russell, R. I., & Mathan, V. I. (1990). A combined TDDA-PVC pH and reference electrode for use in the upper small intestine. Journal of Medical Engineering & Technology, 14(1), 16-20.

A combined TDDA-PVC pH and reference electrode for use in the upper small intestine. / McEwan, G T; Lucas, M L; Denvir, M; Raj, M; McColl, K E; Russell, R I; Mathan, V I.

In: Journal of Medical Engineering & Technology, Vol. 14, No. 1, 1990, p. 16-20.

Research output: Contribution to journalArticle

McEwan, GT, Lucas, ML, Denvir, M, Raj, M, McColl, KE, Russell, RI & Mathan, VI 1990, 'A combined TDDA-PVC pH and reference electrode for use in the upper small intestine', Journal of Medical Engineering & Technology, vol. 14, no. 1, pp. 16-20.
McEwan, G T ; Lucas, M L ; Denvir, M ; Raj, M ; McColl, K E ; Russell, R I ; Mathan, V I. / A combined TDDA-PVC pH and reference electrode for use in the upper small intestine. In: Journal of Medical Engineering & Technology. 1990 ; Vol. 14, No. 1. pp. 16-20.
@article{1803489d19c64bc4b13c93a675e92002,
title = "A combined TDDA-PVC pH and reference electrode for use in the upper small intestine",
abstract = "Incorporation of a ligand into polyvinylchloride allows the production of ion selective electrodes that are soft-bodied and disposable. With features make them especially suitable for clinical, particularly gastroenterological, investigations. We report here on the construction of a combined reference and pH electrode suitable for use at jejunal biopsy. With this type of pH electrode, the pH of the mucosal surface of the jejunum in UK and in Indian subjects, without evidence of upper gastrointestinal disease, was about pH 6.0. This was almost identical to previous values measured using a separate reference electrode. Both the polymer electrode and a suitable data logger can be conveniently produced in the laboratory and compare favourably with commercially available systems, provided the range of pH likely to be encountered is within the operating range of the incorporated ligand.",
keywords = "Amines, Biopsy, Celiac Disease, Electrodes, Equipment Design, Humans, Hydrogen-Ion Concentration, Intestinal Mucosa, Jejunum, Ligands, Polyvinyl Chloride, Reference Values",
author = "McEwan, {G T} and Lucas, {M L} and M Denvir and M Raj and McColl, {K E} and Russell, {R I} and Mathan, {V I}",
year = "1990",
language = "English",
volume = "14",
pages = "16--20",
journal = "Journal of Medical Engineering & Technology",
issn = "0309-1902",
publisher = "Taylor & Francis",
number = "1",

}

TY - JOUR

T1 - A combined TDDA-PVC pH and reference electrode for use in the upper small intestine

AU - McEwan, G T

AU - Lucas, M L

AU - Denvir, M

AU - Raj, M

AU - McColl, K E

AU - Russell, R I

AU - Mathan, V I

PY - 1990

Y1 - 1990

N2 - Incorporation of a ligand into polyvinylchloride allows the production of ion selective electrodes that are soft-bodied and disposable. With features make them especially suitable for clinical, particularly gastroenterological, investigations. We report here on the construction of a combined reference and pH electrode suitable for use at jejunal biopsy. With this type of pH electrode, the pH of the mucosal surface of the jejunum in UK and in Indian subjects, without evidence of upper gastrointestinal disease, was about pH 6.0. This was almost identical to previous values measured using a separate reference electrode. Both the polymer electrode and a suitable data logger can be conveniently produced in the laboratory and compare favourably with commercially available systems, provided the range of pH likely to be encountered is within the operating range of the incorporated ligand.

AB - Incorporation of a ligand into polyvinylchloride allows the production of ion selective electrodes that are soft-bodied and disposable. With features make them especially suitable for clinical, particularly gastroenterological, investigations. We report here on the construction of a combined reference and pH electrode suitable for use at jejunal biopsy. With this type of pH electrode, the pH of the mucosal surface of the jejunum in UK and in Indian subjects, without evidence of upper gastrointestinal disease, was about pH 6.0. This was almost identical to previous values measured using a separate reference electrode. Both the polymer electrode and a suitable data logger can be conveniently produced in the laboratory and compare favourably with commercially available systems, provided the range of pH likely to be encountered is within the operating range of the incorporated ligand.

KW - Amines

KW - Biopsy

KW - Celiac Disease

KW - Electrodes

KW - Equipment Design

KW - Humans

KW - Hydrogen-Ion Concentration

KW - Intestinal Mucosa

KW - Jejunum

KW - Ligands

KW - Polyvinyl Chloride

KW - Reference Values

M3 - Article

VL - 14

SP - 16

EP - 20

JO - Journal of Medical Engineering & Technology

JF - Journal of Medical Engineering & Technology

SN - 0309-1902

IS - 1

ER -