A combined TDDA-PVC pH and reference electrode for use in the upper small intestine

Gordon T.A. McEwan, M L Lucas, M Denvir, M Raj, K E McColl, R I Russell, V I Mathan

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


Incorporation of a ligand into polyvinylchloride allows the production of ion selective electrodes that are soft-bodied and disposable. With features make them especially suitable for clinical, particularly gastroenterological, investigations. We report here on the construction of a combined reference and pH electrode suitable for use at jejunal biopsy. With this type of pH electrode, the pH of the mucosal surface of the jejunum in UK and in Indian subjects, without evidence of upper gastrointestinal disease, was about pH 6.0. This was almost identical to previous values measured using a separate reference electrode. Both the polymer electrode and a suitable data logger can be conveniently produced in the laboratory and compare favourably with commercially available systems, provided the range of pH likely to be encountered is within the operating range of the incorporated ligand.
Original languageEnglish
Pages (from-to)16-20
Number of pages5
JournalJournal of Medical Engineering & Technology
Issue number1
Publication statusPublished - 1990


  • Amines
  • Biopsy
  • Celiac Disease
  • Electrodes
  • Equipment Design
  • Humans
  • Hydrogen-Ion Concentration
  • Intestinal Mucosa
  • Jejunum
  • Ligands
  • Polyvinyl Chloride
  • Reference Values


Dive into the research topics of 'A combined TDDA-PVC pH and reference electrode for use in the upper small intestine'. Together they form a unique fingerprint.

Cite this