A computer model of the Bystander effect: effects of individual behaviours on the population response

M. C. Richard; R. P. Webb; K. J. Kirkby; N. F. Kirkby

doi:10.1016/j.apradiso.2008.06.037

A computer model of the Bystander effect: effects of individual behaviours on the population response

M. C. Richard, R. P. Webb, K. J. Kirkby, N. F. Kirkby

Institute for Complex Systems and Mathematical Biology (ICSMB)

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

A computer program was written to test assumptions on the mechanisms of response of cells to radiation. Current assumptions were implemented in the model and simulations were run to predict the survival of the hamster cell line V79 to irradiation with focused C(K) X-rays, 250 keV X-rays or 3.2 MeV protons. The model could reproduce the different types of response and support the idea that the response at low doses is non-linear and may be independent of LET. (C) 2008 Published by Elsevier Ltd.

Original language	English
Pages (from-to)	440-442
Number of pages	3
Journal	Applied Radiation and Isotopes
Volume	67
Issue number	3
DOIs	https://doi.org/10.1016/j.apradiso.2008.06.037
Publication status	Published - Mar 2009

Keywords

x-rays
radiation
cell
exposure

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10.1016/j.apradiso.2008.06.037

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abstract = "A computer program was written to test assumptions on the mechanisms of response of cells to radiation. Current assumptions were implemented in the model and simulations were run to predict the survival of the hamster cell line V79 to irradiation with focused C(K) X-rays, 250 keV X-rays or 3.2 MeV protons. The model could reproduce the different types of response and support the idea that the response at low doses is non-linear and may be independent of LET. (C) 2008 Published by Elsevier Ltd.",

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author = "Richard, {M. C.} and Webb, {R. P.} and Kirkby, {K. J.} and Kirkby, {N. F.}",

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AU - Kirkby, K. J.

AU - Kirkby, N. F.

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N2 - A computer program was written to test assumptions on the mechanisms of response of cells to radiation. Current assumptions were implemented in the model and simulations were run to predict the survival of the hamster cell line V79 to irradiation with focused C(K) X-rays, 250 keV X-rays or 3.2 MeV protons. The model could reproduce the different types of response and support the idea that the response at low doses is non-linear and may be independent of LET. (C) 2008 Published by Elsevier Ltd.

AB - A computer program was written to test assumptions on the mechanisms of response of cells to radiation. Current assumptions were implemented in the model and simulations were run to predict the survival of the hamster cell line V79 to irradiation with focused C(K) X-rays, 250 keV X-rays or 3.2 MeV protons. The model could reproduce the different types of response and support the idea that the response at low doses is non-linear and may be independent of LET. (C) 2008 Published by Elsevier Ltd.

KW - x-rays

KW - radiation

KW - cell

KW - exposure

U2 - 10.1016/j.apradiso.2008.06.037

DO - 10.1016/j.apradiso.2008.06.037

M3 - Article

VL - 67

SP - 440

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JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

SN - 0969-8043

IS - 3

ER -

A computer model of the Bystander effect: effects of individual behaviours on the population response

Abstract

Keywords

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