A developmental program for Candida commensalism

Neil A R Gow*

*Corresponding author for this work

Research output: Contribution to journalLetter

12 Citations (Scopus)

Abstract

Candida albicans is a frequent pathogen of immunologically compromised individuals, but it is an even more common commensal of healthy humans, where it resides in the gut in a benign state. A new study shows that a specific commensal form of the fungus is induced in the gut through a developmental program that downregulates virulence factors and induces metabolic functions, enabling it to thrive on the nutrients that are available in the large intestine without damaging its host.

Original languageEnglish
Pages (from-to)967-968
Number of pages2
JournalNature Genetics
Volume45
Issue number9
Early online date23 Aug 2013
DOIs
Publication statusPublished - Sep 2013

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ASJC Scopus subject areas

  • Genetics

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