A facile analytical method for reliable selectivity examination in cofactor NADH regeneration

Tony Saba, Joseph W. H. Burnett, Jianwei Li, Panagiotis Kechagiopoulos, Xiaodong Wang*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

This study demonstrates a novel method to quantify selective (1,4-NADH) and unselective products (1,2- and 1,6-NADH) in NADH regeneration using combined UV-Vis spectroscopy and biological assays. The validity of the proposed method was tested in the Pt/C promoted NAD+ hydrogenation using hydrogen as reducing agent.
Original languageEnglish
Pages (from-to)1231-1234
Number of pages4
JournalChemical Communications
Volume56
Issue number8
Early online date18 Dec 2019
DOIs
Publication statusPublished - 25 Jan 2020

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Reducing agents
Ultraviolet spectroscopy
NAD
Hydrogenation
Assays
Hydrogen
Reducing Agents

Cite this

A facile analytical method for reliable selectivity examination in cofactor NADH regeneration. / Saba, Tony; Burnett, Joseph W. H.; Li, Jianwei; Kechagiopoulos, Panagiotis; Wang, Xiaodong.

In: Chemical Communications, Vol. 56, No. 8, 25.01.2020, p. 1231-1234.

Research output: Contribution to journalArticle

Saba, Tony ; Burnett, Joseph W. H. ; Li, Jianwei ; Kechagiopoulos, Panagiotis ; Wang, Xiaodong. / A facile analytical method for reliable selectivity examination in cofactor NADH regeneration. In: Chemical Communications. 2020 ; Vol. 56, No. 8. pp. 1231-1234.
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