A gene encoding a homologue of dolichol phosphate-b-D mannose synthase is required for infection of Streptomyces coelicolor A3(2) by phage fC31

D. A. Cowlishaw, Margaret Caroline MacHin Smith

Research output: Contribution to journalArticle

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Abstract

We have shown previously that a gene encoding a homologue to the eukaryotic dolichol-phosphate-D-mannose, protein O-D-mannosyltransferase, was required for phiC31 infection of Streptomyces coelicolor. Here we show that a gene encoding the homologue to dolichol-phosphate-mannose synthase is also essential for phage sensitivity. These data confirm the role of glycosylation in the phage receptor for phiC31 in S. coelicolor.

Original languageEnglish
Pages (from-to)6081-6083
Number of pages2
JournalJournal of Bacteriology
Volume184
DOIs
Publication statusPublished - 2002

Keywords

  • ESCHERICHIA-COLI
  • TAIL FIBER
  • CLONING
  • PROTEIN
  • GLYCOSYLATION
  • SEQUENCE
  • DNA

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