A high oat-bran intake does not impair zinc absorption in humans when added to a low-fiber animal protein-based diet

B Sandstrom, S Bugel, B A McGaw, J Price, Martin David Reid

    Research output: Contribution to journalArticle

    29 Citations (Scopus)

    Abstract

    Oat bran has a high phytate content and a low or inactivated phytase activity. A high intake of oat bran could therefore result in an impaired absorption of trace elements. The effect of a mean daily intake of 142 g of oat bran (102 g/10 MJ) on absorption of zinc was evaluated by the use of stable isotopes and fecal monitoring in 12 healthy subjects (6 males and 6 females). Each subject participated in two separate diet periods each of 21 d with identical low-fiber diets and with oat bran added in one of the periods. The oat bran was incorporated into bread and served at three daily main meals. The intake of zinc and phytate per 10 MJ was 138 mu mol (9.0 mg) and 0.5 mmol, respectively, in the low-fiber period and 225 mu mol (14.7 mg) and 4.0 mmol, respectively, in the oat bran period. Stable isotopes of zinc (Zn-70) were added to the diets at d 7 of each period. The fractional absorptions (means +/- SD) of zinc from the low-fiber and oat bran diets were 0.48 +/- 0.11 and 0.40 +/- 0.15 (P = 0.07), respectively. The higher zinc content in the oat bran period resulted in a greater amount of zinc absorbed (64 +/- 19 mu mol and 99 +/- 51 mu mol, respectively, P = 0.009). Balance data suggest that the higher absorbed amount of zinc resulted in correspondingly higher intestinal endogenous excretion of zinc. In conclusion, the absorption of zinc was high and not affected by addition of oat bran.

    Original languageEnglish
    Pages (from-to)594-599
    Number of pages6
    JournalThe Journal of Nutrition
    Volume130
    Issue number3
    Publication statusPublished - Mar 2000

    Keywords

    • oat bran
    • zinc
    • phytate
    • stable isotopes
    • humans
    • birth-weight infants
    • stable-isotope
    • iron-absorption
    • composite meals
    • phytate content
    • young men
    • copper
    • wheat
    • bioavailability
    • magnesium

    Cite this

    Sandstrom, B., Bugel, S., McGaw, B. A., Price, J., & Reid, M. D. (2000). A high oat-bran intake does not impair zinc absorption in humans when added to a low-fiber animal protein-based diet. The Journal of Nutrition, 130(3), 594-599.

    A high oat-bran intake does not impair zinc absorption in humans when added to a low-fiber animal protein-based diet. / Sandstrom, B ; Bugel, S ; McGaw, B A ; Price, J ; Reid, Martin David.

    In: The Journal of Nutrition, Vol. 130, No. 3, 03.2000, p. 594-599.

    Research output: Contribution to journalArticle

    Sandstrom, B, Bugel, S, McGaw, BA, Price, J & Reid, MD 2000, 'A high oat-bran intake does not impair zinc absorption in humans when added to a low-fiber animal protein-based diet', The Journal of Nutrition, vol. 130, no. 3, pp. 594-599.
    Sandstrom, B ; Bugel, S ; McGaw, B A ; Price, J ; Reid, Martin David. / A high oat-bran intake does not impair zinc absorption in humans when added to a low-fiber animal protein-based diet. In: The Journal of Nutrition. 2000 ; Vol. 130, No. 3. pp. 594-599.
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    abstract = "Oat bran has a high phytate content and a low or inactivated phytase activity. A high intake of oat bran could therefore result in an impaired absorption of trace elements. The effect of a mean daily intake of 142 g of oat bran (102 g/10 MJ) on absorption of zinc was evaluated by the use of stable isotopes and fecal monitoring in 12 healthy subjects (6 males and 6 females). Each subject participated in two separate diet periods each of 21 d with identical low-fiber diets and with oat bran added in one of the periods. The oat bran was incorporated into bread and served at three daily main meals. The intake of zinc and phytate per 10 MJ was 138 mu mol (9.0 mg) and 0.5 mmol, respectively, in the low-fiber period and 225 mu mol (14.7 mg) and 4.0 mmol, respectively, in the oat bran period. Stable isotopes of zinc (Zn-70) were added to the diets at d 7 of each period. The fractional absorptions (means +/- SD) of zinc from the low-fiber and oat bran diets were 0.48 +/- 0.11 and 0.40 +/- 0.15 (P = 0.07), respectively. The higher zinc content in the oat bran period resulted in a greater amount of zinc absorbed (64 +/- 19 mu mol and 99 +/- 51 mu mol, respectively, P = 0.009). Balance data suggest that the higher absorbed amount of zinc resulted in correspondingly higher intestinal endogenous excretion of zinc. In conclusion, the absorption of zinc was high and not affected by addition of oat bran.",
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    T1 - A high oat-bran intake does not impair zinc absorption in humans when added to a low-fiber animal protein-based diet

    AU - Sandstrom, B

    AU - Bugel, S

    AU - McGaw, B A

    AU - Price, J

    AU - Reid, Martin David

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    N2 - Oat bran has a high phytate content and a low or inactivated phytase activity. A high intake of oat bran could therefore result in an impaired absorption of trace elements. The effect of a mean daily intake of 142 g of oat bran (102 g/10 MJ) on absorption of zinc was evaluated by the use of stable isotopes and fecal monitoring in 12 healthy subjects (6 males and 6 females). Each subject participated in two separate diet periods each of 21 d with identical low-fiber diets and with oat bran added in one of the periods. The oat bran was incorporated into bread and served at three daily main meals. The intake of zinc and phytate per 10 MJ was 138 mu mol (9.0 mg) and 0.5 mmol, respectively, in the low-fiber period and 225 mu mol (14.7 mg) and 4.0 mmol, respectively, in the oat bran period. Stable isotopes of zinc (Zn-70) were added to the diets at d 7 of each period. The fractional absorptions (means +/- SD) of zinc from the low-fiber and oat bran diets were 0.48 +/- 0.11 and 0.40 +/- 0.15 (P = 0.07), respectively. The higher zinc content in the oat bran period resulted in a greater amount of zinc absorbed (64 +/- 19 mu mol and 99 +/- 51 mu mol, respectively, P = 0.009). Balance data suggest that the higher absorbed amount of zinc resulted in correspondingly higher intestinal endogenous excretion of zinc. In conclusion, the absorption of zinc was high and not affected by addition of oat bran.

    AB - Oat bran has a high phytate content and a low or inactivated phytase activity. A high intake of oat bran could therefore result in an impaired absorption of trace elements. The effect of a mean daily intake of 142 g of oat bran (102 g/10 MJ) on absorption of zinc was evaluated by the use of stable isotopes and fecal monitoring in 12 healthy subjects (6 males and 6 females). Each subject participated in two separate diet periods each of 21 d with identical low-fiber diets and with oat bran added in one of the periods. The oat bran was incorporated into bread and served at three daily main meals. The intake of zinc and phytate per 10 MJ was 138 mu mol (9.0 mg) and 0.5 mmol, respectively, in the low-fiber period and 225 mu mol (14.7 mg) and 4.0 mmol, respectively, in the oat bran period. Stable isotopes of zinc (Zn-70) were added to the diets at d 7 of each period. The fractional absorptions (means +/- SD) of zinc from the low-fiber and oat bran diets were 0.48 +/- 0.11 and 0.40 +/- 0.15 (P = 0.07), respectively. The higher zinc content in the oat bran period resulted in a greater amount of zinc absorbed (64 +/- 19 mu mol and 99 +/- 51 mu mol, respectively, P = 0.009). Balance data suggest that the higher absorbed amount of zinc resulted in correspondingly higher intestinal endogenous excretion of zinc. In conclusion, the absorption of zinc was high and not affected by addition of oat bran.

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    KW - phytate

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    KW - humans

    KW - birth-weight infants

    KW - stable-isotope

    KW - iron-absorption

    KW - composite meals

    KW - phytate content

    KW - young men

    KW - copper

    KW - wheat

    KW - bioavailability

    KW - magnesium

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    JO - The Journal of Nutrition

    JF - The Journal of Nutrition

    SN - 0022-3166

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    ER -