A neglected epidemic: fungal infections in HIV/AIDS

Darius Armstrong-James; Graeme Meintjes; Gordon D Brown

doi:10.1016/j.tim.2014.01.001

A neglected epidemic: fungal infections in HIV/AIDS

Darius Armstrong-James, Graeme Meintjes, Gordon D Brown

Applied Medicine

Research output: Contribution to journal › Article › peer-review

240 Citations (Scopus)

Abstract

Invasive fungal infections (IFIs) are a major cause of HIV-related mortality globally. Despite widespread rollout of combined antiretroviral therapy, there are still up to 1 million deaths annually from IFIs, accounting for 50% of all AIDS-related death. A historic failure to focus efforts on the IFIs that kill so many HIV patients has led to fundamental flaws in the management of advanced HIV infection. This review, based on the EMBO AIDS-Related Mycoses Workshop in Cape Town in July 2013, summarizes the current state of the-art in AIDS-related mycoses, and the key action points required to improve outcomes from these devastating infections.

Original language	English
Pages (from-to)	120-127
Number of pages	8
Journal	Trends in Microbiology
Volume	22
Issue number	3
Early online date	13 Feb 2014
DOIs	https://doi.org/10.1016/j.tim.2014.01.001
Publication status	Published - Mar 2014

Bibliographical note

Copyright © 2014 Elsevier Ltd. All rights reserved.

We thank the Welcome Trust for funding. D.A.J. is supported by an MRC Clinician Scientist Fellowship.

Keywords

HIV
fungal infection
immunity
AIDS
mycoses

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.tim.2014.01.001

Cite this

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A neglected epidemic: fungal infections in HIV/AIDS

Abstract

Bibliographical note

Keywords

UN SDGs

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