A new algorithm to reduce T-wave over-sensing based on phase space reconstruction in S-ICD system.

Hanjie Chen* (Corresponding Author), Benedict Wiles, Paul Roberts, John M Morgan, Koushik Maharatna

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Background and objectiveThe subcutaneous implantable cardioverter defibrillator (S-ICD) reduces mortality in individuals at high risk of sudden arrhythmic death, by rapid defibrillation of life-threatening arrhythmia. Unfortunately, S-ICD recipients are also at risk of inappropriate shock therapies, which themselves are associated with increased rates of mortality and morbidity. The commonest cause of inappropriate shock therapies is T wave oversensing (TWOS), where T waves are incorrectly counted as R waves leading to an overestimation of heart rate. It is important to develop a method to reduce TWOS and improve the accuracy of R-peak detection in S-ICD system.MethodsThis paper introduces a novel algorithm to reduce TWOS based on phase space reconstruction (PSR); a common method used to analyse the chaotic characteristics of non-linear signals.ResultsThe algorithm was evaluated against 34 records from University Hospital Southampton (UHS) and all 48 records from the MIT-BIH arrhythmia database. In the UHS analysis we demonstrated a sensitivity of 99.88%, a positive predictive value of 99.99% and an accuracy of 99.88% with reductions in TWOS episodes (from 166 to 0). Whilst in the MIT-BIH analysis we demonstrated a sensitivity of 99.87%, a positive predictive value of 99.99% and an accuracy of 99.91% for R wave detection. The average processing time for 1 min ECG signals from all records is 2.9 s.ConclusionsOur algorithm is sensitive for R-wave detection and can effectively reduce the TWOS with low computational complexity, and it would therefore have the potential to reduce inappropriate shock therapies in S-ICD recipients, which would significantly reduce shock related morbidity and mortality, and undoubtedly improving patient's quality of life.
Original languageEnglish
Article number104804
JournalComputers in Biology and Medicine
Volume137
Early online date26 Aug 2021
DOIs
Publication statusPublished - Oct 2021

Keywords

  • S-ICD
  • R-peak detection
  • T-wave oversensing
  • Phase space reconstruction

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