A rapid monitoring method for inorganic arsenic in rice flour using reversed phase-high performance liquid chromatography-inductively coupled plasma mass spectrometry

Tomohiro Narukawa, Koichi Chiba, Savarin Sinaviwat, Jörg Feldmann

Research output: Contribution to journalArticle

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Abstract

A new rapid monitoring method by means of high performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) following the heat-assisted extraction was developed for measurement of total inorganic arsenic species in rice flour. As(III) and As(V) eluted at the same retention time and completely separated from organoarsenic species by an isocratic elution program on a reversed phase column. Therefore, neither ambiguous oxidation of arsenite to arsenate nor the integration of two peaks were necessary to determine directly the target analyte inorganic arsenic. Rapid injection allowed measuring 3 replicates within 6 min and this combined with a quantitative extraction of all arsenic species from rice flour by a 15 min HNO3-H2O2 extraction makes this the fastest laboratory based method for inorganic arsenic in rice flour.
Original languageEnglish
Pages (from-to)129-136
Number of pages8
JournalJournal of Chromatography A
Volume1479
Early online date5 Dec 2016
DOIs
Publication statusPublished - 6 Jan 2017

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Inductively coupled plasma mass spectrometry
High performance liquid chromatography
Arsenic
Flour
Mass Spectrometry
High Pressure Liquid Chromatography
Monitoring
Hot Temperature
Oxidation
Injections
Oryza

Keywords

  • arsenic speciation
  • HPLC-ICP-MS
  • Inorganic arsenic determination
  • Rice flour
  • Risk assessment
  • Extraction

Cite this

A rapid monitoring method for inorganic arsenic in rice flour using reversed phase-high performance liquid chromatography-inductively coupled plasma mass spectrometry. / Narukawa, Tomohiro; Chiba, Koichi; Sinaviwat, Savarin; Feldmann, Jörg.

In: Journal of Chromatography A, Vol. 1479, 06.01.2017, p. 129-136.

Research output: Contribution to journalArticle

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