A rapid monitoring method for inorganic arsenic in rice flour using reversed phase-high performance liquid chromatography-inductively coupled plasma mass spectrometry

Tomohiro Narukawa; Koichi Chiba; Savarin Sinaviwat; Jörg Feldmann

doi:10.1016/j.chroma.2016.12.001

A rapid monitoring method for inorganic arsenic in rice flour using reversed phase-high performance liquid chromatography-inductively coupled plasma mass spectrometry

Tomohiro Narukawa, Koichi Chiba, Savarin Sinaviwat, Jörg Feldmann

Chemistry

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35 Citations (Scopus)

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Abstract

A new rapid monitoring method by means of high performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) following the heat-assisted extraction was developed for measurement of total inorganic arsenic species in rice flour. As(III) and As(V) eluted at the same retention time and completely separated from organoarsenic species by an isocratic elution program on a reversed phase column. Therefore, neither ambiguous oxidation of arsenite to arsenate nor the integration of two peaks were necessary to determine directly the target analyte inorganic arsenic. Rapid injection allowed measuring 3 replicates within 6 min and this combined with a quantitative extraction of all arsenic species from rice flour by a 15 min HNO3-H2O2 extraction makes this the fastest laboratory based method for inorganic arsenic in rice flour.

Original language	English
Pages (from-to)	129-136
Number of pages	8
Journal	Journal of Chromatography A
Volume	1479
Early online date	5 Dec 2016
DOIs	https://doi.org/10.1016/j.chroma.2016.12.001
Publication status	Published - 6 Jan 2017

Bibliographical note

Savarin Sinaviwat thanks the Royal Thai Government Scholarship for financial support.

Keywords

arsenic speciation
HPLC-ICP-MS
Inorganic arsenic determination
Rice flour
Risk assessment
Extraction

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10.1016/j.chroma.2016.12.001Licence: Unspecified

Accepted Manuscript
© 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Accepted author manuscript, 0.98 MBLicence: Unspecified

Providing an evidence base for a maximum permissible level of inorganic arsenic in rice
Jörg Feldmann (Participant), Andrew Alexander Meharg (Participant), Andrea Raab (Participant) & Eva Maria Krupp (Participant)
Impact

Cite this

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title = "A rapid monitoring method for inorganic arsenic in rice flour using reversed phase-high performance liquid chromatography-inductively coupled plasma mass spectrometry",

abstract = "A new rapid monitoring method by means of high performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) following the heat-assisted extraction was developed for measurement of total inorganic arsenic species in rice flour. As(III) and As(V) eluted at the same retention time and completely separated from organoarsenic species by an isocratic elution program on a reversed phase column. Therefore, neither ambiguous oxidation of arsenite to arsenate nor the integration of two peaks were necessary to determine directly the target analyte inorganic arsenic. Rapid injection allowed measuring 3 replicates within 6 min and this combined with a quantitative extraction of all arsenic species from rice flour by a 15 min HNO3-H2O2 extraction makes this the fastest laboratory based method for inorganic arsenic in rice flour.",

keywords = "arsenic speciation, HPLC-ICP-MS, Inorganic arsenic determination, Rice flour, Risk assessment, Extraction",

author = "Tomohiro Narukawa and Koichi Chiba and Savarin Sinaviwat and J{\"o}rg Feldmann",

note = "Savarin Sinaviwat thanks the Royal Thai Government Scholarship for financial support.",

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T1 - A rapid monitoring method for inorganic arsenic in rice flour using reversed phase-high performance liquid chromatography-inductively coupled plasma mass spectrometry

AU - Narukawa, Tomohiro

AU - Chiba, Koichi

AU - Sinaviwat, Savarin

AU - Feldmann, Jörg

N1 - Savarin Sinaviwat thanks the Royal Thai Government Scholarship for financial support.

PY - 2017/1/6

Y1 - 2017/1/6

N2 - A new rapid monitoring method by means of high performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) following the heat-assisted extraction was developed for measurement of total inorganic arsenic species in rice flour. As(III) and As(V) eluted at the same retention time and completely separated from organoarsenic species by an isocratic elution program on a reversed phase column. Therefore, neither ambiguous oxidation of arsenite to arsenate nor the integration of two peaks were necessary to determine directly the target analyte inorganic arsenic. Rapid injection allowed measuring 3 replicates within 6 min and this combined with a quantitative extraction of all arsenic species from rice flour by a 15 min HNO3-H2O2 extraction makes this the fastest laboratory based method for inorganic arsenic in rice flour.

AB - A new rapid monitoring method by means of high performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) following the heat-assisted extraction was developed for measurement of total inorganic arsenic species in rice flour. As(III) and As(V) eluted at the same retention time and completely separated from organoarsenic species by an isocratic elution program on a reversed phase column. Therefore, neither ambiguous oxidation of arsenite to arsenate nor the integration of two peaks were necessary to determine directly the target analyte inorganic arsenic. Rapid injection allowed measuring 3 replicates within 6 min and this combined with a quantitative extraction of all arsenic species from rice flour by a 15 min HNO3-H2O2 extraction makes this the fastest laboratory based method for inorganic arsenic in rice flour.

KW - arsenic speciation

KW - HPLC-ICP-MS

KW - Inorganic arsenic determination

KW - Rice flour

KW - Risk assessment

KW - Extraction

U2 - 10.1016/j.chroma.2016.12.001

DO - 10.1016/j.chroma.2016.12.001

M3 - Article

SN - 0021-9673

VL - 1479

SP - 129

EP - 136

JO - Journal of Chromatography A

JF - Journal of Chromatography A

ER -

A rapid monitoring method for inorganic arsenic in rice flour using reversed phase-high performance liquid chromatography-inductively coupled plasma mass spectrometry

Abstract

Bibliographical note

Keywords

Access to Document

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Impacts

Providing an evidence base for a maximum permissible level of inorganic arsenic in rice

Cite this