A self-help diet and physical activity intervention with dietetic support for weight management in men treated for prostate cancer: pilot study of the PRO-MAN randomised controlled trial

H. Mohamad, M. Ntessalen, L. C. A. Craig (Corresponding Author), J. Clark, S. Fielding, J. N'Dow, S. D. Heys, G. McNeill

Research output: Contribution to journalArticle

Abstract

Overweight and obesity may increase risk of disease progression in men with prostate cancer but there have been few studies of weight loss interventions in this patient group. Based on existing literature and patient preferences we designed a self-help diet and physical activity intervention with telephone-based dietitian support. Men treated for prostate cancer who were overweight or obese were randomised to intervention or wait-list mini-intervention groups. The intervention group had an initial group meeting, a supporting letter from their urological consultant, three telephone dietitian consultations at 4 week intervals, a pedometer and access to web-based diet and physical activity resources. At 12 weeks, men in both groups were given digital scales for providing follow-up weight measurements and the wait-list group received a mini-intervention of the supporting letter, a pedometer and access to the web-based resources. Sixty-two men were randomised; 54 completed baseline and 12 week measurements and 51 and 27 provided measurements at 6 and 12 months respectively. In a repeated measures model, mean (95% CI) difference in weight change between groups (wait-list mini-intervention minus intervention) at 12 weeks was -2.13 (-3.44, -0.82) kg (p=0.002). At 12 months the corresponding value was -2.43 (-4.50, -0.37) kg (p=0.022). Mean (95% CI) difference in global QoL score change between groups at 12 weeks was 12.3 (4.93, 19.7) (p=0.002); at 12 months there were no significant differences between groups. Results suggest the potential of self-help diet and physical activity intervention with trained support for modest but sustained weight loss in this patient group
Original languageEnglish
Number of pages25
JournalBritish Journal of Nutrition
Early online date10 Jun 2019
DOIs
Publication statusE-pub ahead of print - 10 Jun 2019

Fingerprint

Dietetics
Prostatic Neoplasms
Randomized Controlled Trials
Exercise
Diet
Weights and Measures
Nutritionists
Telephone
Weight Loss
Group Processes
Patient Preference
Consultants
Disease Progression
Referral and Consultation
Obesity

Keywords

  • prostate cancer
  • diet
  • physical activity
  • overweight
  • obesity
  • weight loss
  • pilot study
  • randomised controlled trial
  • Obesity
  • Physical activity
  • Weight loss
  • Overweight
  • Pilot study
  • Diet
  • Randomised controlled trial
  • Prostate cancer

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Medicine (miscellaneous)

Cite this

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title = "A self-help diet and physical activity intervention with dietetic support for weight management in men treated for prostate cancer: pilot study of the PRO-MAN randomised controlled trial",
abstract = "Overweight and obesity may increase risk of disease progression in men with prostate cancer but there have been few studies of weight loss interventions in this patient group. Based on existing literature and patient preferences we designed a self-help diet and physical activity intervention with telephone-based dietitian support. Men treated for prostate cancer who were overweight or obese were randomised to intervention or wait-list mini-intervention groups. The intervention group had an initial group meeting, a supporting letter from their urological consultant, three telephone dietitian consultations at 4 week intervals, a pedometer and access to web-based diet and physical activity resources. At 12 weeks, men in both groups were given digital scales for providing follow-up weight measurements and the wait-list group received a mini-intervention of the supporting letter, a pedometer and access to the web-based resources. Sixty-two men were randomised; 54 completed baseline and 12 week measurements and 51 and 27 provided measurements at 6 and 12 months respectively. In a repeated measures model, mean (95{\%} CI) difference in weight change between groups (wait-list mini-intervention minus intervention) at 12 weeks was -2.13 (-3.44, -0.82) kg (p=0.002). At 12 months the corresponding value was -2.43 (-4.50, -0.37) kg (p=0.022). Mean (95{\%} CI) difference in global QoL score change between groups at 12 weeks was 12.3 (4.93, 19.7) (p=0.002); at 12 months there were no significant differences between groups. Results suggest the potential of self-help diet and physical activity intervention with trained support for modest but sustained weight loss in this patient group",
keywords = "prostate cancer, diet, physical activity, overweight, obesity, weight loss, pilot study, randomised controlled trial, Obesity, Physical activity, Weight loss, Overweight, Pilot study, Diet, Randomised controlled trial, Prostate cancer",
author = "H. Mohamad and M. Ntessalen and Craig, {L. C. A.} and J. Clark and S. Fielding and J. N'Dow and Heys, {S. D.} and G. McNeill",
note = "Acknowledgements: We thank the Urology consultants at Aberdeen Royal Infirmary and staff of the UCAN centre, especially Paul Mannion, for support with the conduct of the study and the CLAN centre staff for hosting intervention group meetings. Funding: HM carried out this work while in receipt of a PhD scholarship from the Government of Malaysia. We thank Cancer Research in Aberdeen and NE Scotland (CRANES) for financial support for the pedometers and weighing scales. LCAC and GMcN acknowledge support from the RESAS programme of the Scottish Government.",
year = "2019",
month = "6",
day = "10",
doi = "10.1017/S0007114519001090",
language = "English",
journal = "British Journal of Nutrition",
issn = "0007-1145",
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T1 - A self-help diet and physical activity intervention with dietetic support for weight management in men treated for prostate cancer

T2 - pilot study of the PRO-MAN randomised controlled trial

AU - Mohamad, H.

AU - Ntessalen, M.

AU - Craig, L. C. A.

AU - Clark, J.

AU - Fielding, S.

AU - N'Dow, J.

AU - Heys, S. D.

AU - McNeill, G.

N1 - Acknowledgements: We thank the Urology consultants at Aberdeen Royal Infirmary and staff of the UCAN centre, especially Paul Mannion, for support with the conduct of the study and the CLAN centre staff for hosting intervention group meetings. Funding: HM carried out this work while in receipt of a PhD scholarship from the Government of Malaysia. We thank Cancer Research in Aberdeen and NE Scotland (CRANES) for financial support for the pedometers and weighing scales. LCAC and GMcN acknowledge support from the RESAS programme of the Scottish Government.

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Y1 - 2019/6/10

N2 - Overweight and obesity may increase risk of disease progression in men with prostate cancer but there have been few studies of weight loss interventions in this patient group. Based on existing literature and patient preferences we designed a self-help diet and physical activity intervention with telephone-based dietitian support. Men treated for prostate cancer who were overweight or obese were randomised to intervention or wait-list mini-intervention groups. The intervention group had an initial group meeting, a supporting letter from their urological consultant, three telephone dietitian consultations at 4 week intervals, a pedometer and access to web-based diet and physical activity resources. At 12 weeks, men in both groups were given digital scales for providing follow-up weight measurements and the wait-list group received a mini-intervention of the supporting letter, a pedometer and access to the web-based resources. Sixty-two men were randomised; 54 completed baseline and 12 week measurements and 51 and 27 provided measurements at 6 and 12 months respectively. In a repeated measures model, mean (95% CI) difference in weight change between groups (wait-list mini-intervention minus intervention) at 12 weeks was -2.13 (-3.44, -0.82) kg (p=0.002). At 12 months the corresponding value was -2.43 (-4.50, -0.37) kg (p=0.022). Mean (95% CI) difference in global QoL score change between groups at 12 weeks was 12.3 (4.93, 19.7) (p=0.002); at 12 months there were no significant differences between groups. Results suggest the potential of self-help diet and physical activity intervention with trained support for modest but sustained weight loss in this patient group

AB - Overweight and obesity may increase risk of disease progression in men with prostate cancer but there have been few studies of weight loss interventions in this patient group. Based on existing literature and patient preferences we designed a self-help diet and physical activity intervention with telephone-based dietitian support. Men treated for prostate cancer who were overweight or obese were randomised to intervention or wait-list mini-intervention groups. The intervention group had an initial group meeting, a supporting letter from their urological consultant, three telephone dietitian consultations at 4 week intervals, a pedometer and access to web-based diet and physical activity resources. At 12 weeks, men in both groups were given digital scales for providing follow-up weight measurements and the wait-list group received a mini-intervention of the supporting letter, a pedometer and access to the web-based resources. Sixty-two men were randomised; 54 completed baseline and 12 week measurements and 51 and 27 provided measurements at 6 and 12 months respectively. In a repeated measures model, mean (95% CI) difference in weight change between groups (wait-list mini-intervention minus intervention) at 12 weeks was -2.13 (-3.44, -0.82) kg (p=0.002). At 12 months the corresponding value was -2.43 (-4.50, -0.37) kg (p=0.022). Mean (95% CI) difference in global QoL score change between groups at 12 weeks was 12.3 (4.93, 19.7) (p=0.002); at 12 months there were no significant differences between groups. Results suggest the potential of self-help diet and physical activity intervention with trained support for modest but sustained weight loss in this patient group

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KW - Physical activity

KW - Weight loss

KW - Overweight

KW - Pilot study

KW - Diet

KW - Randomised controlled trial

KW - Prostate cancer

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