TY - JOUR
T1 - A tale of two yeasts
T2 - Saccharomyces cerevisiae as a therapeutic against candidiasis
AU - Wilson, Duncan
N1 - Funding
DW is supported by a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (102549/Z/13/Z), a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology (097377/Z/11/Z), the MRC and University of Aberdeen (MR/N006364/1).
PY - 2017
Y1 - 2017
N2 - Normally a benign commensal colonizer of mucosal surfaces such as the gastrointestinal tract, Candida albicans is also one of the most common fungal pathogens of humans, responsible for both superficial as well as life-threatening invasive infections. Arguably the commonest type of infection caused by C. albicans is vulvovaginal candidiasis (VVC), as it affects 75% of women of childbearing age.1 Sobel JD. Vulvovaginal candidosis. Lancet 2007; 369:1961-71; PMID:17560449; http://dx.doi.org 10.1016/S0140-6736(07)60917-9[CrossRef], [PubMed], [Web of Science ®] And unlike many other manifestations of candidiasis, which are associated with particular immune deficiencies, VVC frequently occurs in otherwise healthy women.
AB - Normally a benign commensal colonizer of mucosal surfaces such as the gastrointestinal tract, Candida albicans is also one of the most common fungal pathogens of humans, responsible for both superficial as well as life-threatening invasive infections. Arguably the commonest type of infection caused by C. albicans is vulvovaginal candidiasis (VVC), as it affects 75% of women of childbearing age.1 Sobel JD. Vulvovaginal candidosis. Lancet 2007; 369:1961-71; PMID:17560449; http://dx.doi.org 10.1016/S0140-6736(07)60917-9[CrossRef], [PubMed], [Web of Science ®] And unlike many other manifestations of candidiasis, which are associated with particular immune deficiencies, VVC frequently occurs in otherwise healthy women.
KW - Candida albicans
KW - Saccharomyces cerevisiae
KW - vulvovaginal candidiasis
U2 - 10.1080/21505594.2016.1230580
DO - 10.1080/21505594.2016.1230580
M3 - Editorial
VL - 8
SP - 15
EP - 17
JO - Virulence
JF - Virulence
SN - 2150-5594
IS - 1
ER -