A whole-body NMR imaging machine

James McDonald Strachan Hutchison, W A EDELSTEIN, G Johnson, Thomas William Redpath

Research output: Contribution to journalArticle

Abstract

A nuclear magnetic resonance (NMR) machine capable of producing tomographic sections of the whole human body in vivo has been constructed. This system is based on a four coil, air-core electromagnet producing a field of 0.04 T which corresponds to a proton NMR frequency of 1.7 MHz. The images are produced line by line using a selective excitation technique. Magnetic field gradients up to about 5 mT/m are employed. Electronic subsystems are described here including a radiofrequency (RF) amplitude feedback circuit, an RF power amplifier, a transmit/receive switch, a receiver pre-amplifier and gradient coil drivers. For a single scan through a 103 mm3 sample of human muscle tissue in vivo, the measured proton density uncertainty is 24% and the spin-lattice relaxation time (T1) uncertainty is 74%. Phantom images using CuSO4 solution and in vivo sections through human chest, thighs and head are presented. T1 measurements of human muscle, liver and brain tissue in vivo give results which agree well with T1 values for corresponding rabbit tissues measured in vitro.
Original languageEnglish
Pages (from-to)292-292
Number of pages1
JournalJournal of Computer Assisted Tomography
Volume5
Issue number2
Publication statusPublished - 1981

Cite this

Hutchison, J. M. S., EDELSTEIN, W. A., Johnson, G., & Redpath, T. W. (1981). A whole-body NMR imaging machine. Journal of Computer Assisted Tomography, 5(2), 292-292.

A whole-body NMR imaging machine. / Hutchison, James McDonald Strachan; EDELSTEIN, W A ; Johnson, G; Redpath, Thomas William.

In: Journal of Computer Assisted Tomography, Vol. 5, No. 2, 1981, p. 292-292.

Research output: Contribution to journalArticle

Hutchison, JMS, EDELSTEIN, WA, Johnson, G & Redpath, TW 1981, 'A whole-body NMR imaging machine', Journal of Computer Assisted Tomography, vol. 5, no. 2, pp. 292-292.
Hutchison JMS, EDELSTEIN WA, Johnson G, Redpath TW. A whole-body NMR imaging machine. Journal of Computer Assisted Tomography. 1981;5(2):292-292.
Hutchison, James McDonald Strachan ; EDELSTEIN, W A ; Johnson, G ; Redpath, Thomas William. / A whole-body NMR imaging machine. In: Journal of Computer Assisted Tomography. 1981 ; Vol. 5, No. 2. pp. 292-292.
@article{d3fd9f1d64de4ed2add303785af46bbf,
title = "A whole-body NMR imaging machine",
abstract = "A nuclear magnetic resonance (NMR) machine capable of producing tomographic sections of the whole human body in vivo has been constructed. This system is based on a four coil, air-core electromagnet producing a field of 0.04 T which corresponds to a proton NMR frequency of 1.7 MHz. The images are produced line by line using a selective excitation technique. Magnetic field gradients up to about 5 mT/m are employed. Electronic subsystems are described here including a radiofrequency (RF) amplitude feedback circuit, an RF power amplifier, a transmit/receive switch, a receiver pre-amplifier and gradient coil drivers. For a single scan through a 103 mm3 sample of human muscle tissue in vivo, the measured proton density uncertainty is 24{\%} and the spin-lattice relaxation time (T1) uncertainty is 74{\%}. Phantom images using CuSO4 solution and in vivo sections through human chest, thighs and head are presented. T1 measurements of human muscle, liver and brain tissue in vivo give results which agree well with T1 values for corresponding rabbit tissues measured in vitro.",
author = "Hutchison, {James McDonald Strachan} and EDELSTEIN, {W A} and G Johnson and Redpath, {Thomas William}",
year = "1981",
language = "English",
volume = "5",
pages = "292--292",
journal = "Journal of Computer Assisted Tomography",
issn = "0363-8715",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - A whole-body NMR imaging machine

AU - Hutchison, James McDonald Strachan

AU - EDELSTEIN, W A

AU - Johnson, G

AU - Redpath, Thomas William

PY - 1981

Y1 - 1981

N2 - A nuclear magnetic resonance (NMR) machine capable of producing tomographic sections of the whole human body in vivo has been constructed. This system is based on a four coil, air-core electromagnet producing a field of 0.04 T which corresponds to a proton NMR frequency of 1.7 MHz. The images are produced line by line using a selective excitation technique. Magnetic field gradients up to about 5 mT/m are employed. Electronic subsystems are described here including a radiofrequency (RF) amplitude feedback circuit, an RF power amplifier, a transmit/receive switch, a receiver pre-amplifier and gradient coil drivers. For a single scan through a 103 mm3 sample of human muscle tissue in vivo, the measured proton density uncertainty is 24% and the spin-lattice relaxation time (T1) uncertainty is 74%. Phantom images using CuSO4 solution and in vivo sections through human chest, thighs and head are presented. T1 measurements of human muscle, liver and brain tissue in vivo give results which agree well with T1 values for corresponding rabbit tissues measured in vitro.

AB - A nuclear magnetic resonance (NMR) machine capable of producing tomographic sections of the whole human body in vivo has been constructed. This system is based on a four coil, air-core electromagnet producing a field of 0.04 T which corresponds to a proton NMR frequency of 1.7 MHz. The images are produced line by line using a selective excitation technique. Magnetic field gradients up to about 5 mT/m are employed. Electronic subsystems are described here including a radiofrequency (RF) amplitude feedback circuit, an RF power amplifier, a transmit/receive switch, a receiver pre-amplifier and gradient coil drivers. For a single scan through a 103 mm3 sample of human muscle tissue in vivo, the measured proton density uncertainty is 24% and the spin-lattice relaxation time (T1) uncertainty is 74%. Phantom images using CuSO4 solution and in vivo sections through human chest, thighs and head are presented. T1 measurements of human muscle, liver and brain tissue in vivo give results which agree well with T1 values for corresponding rabbit tissues measured in vitro.

M3 - Article

VL - 5

SP - 292

EP - 292

JO - Journal of Computer Assisted Tomography

JF - Journal of Computer Assisted Tomography

SN - 0363-8715

IS - 2

ER -