Activity monitoring in patients with depression: A systematic review

Christopher Burton, Brian McKinstry, Aurora Szentagotai Tatar, Antoni Serrano-Blanco, Claudia Pagliari, Maria Wolters

Research output: Contribution to journalArticle

90 Citations (Scopus)
1 Downloads (Pure)

Abstract

BACKGROUND: Altered physical activity is an important feature of depression. It is manifested in psychomotor retardation, agitation and withdrawal from engagement in normal activities. Modern devices for activity monitoring (actigraphs) make it possible to monitor physical activity unobtrusively but the validity of actigraphy as an indicator of mood state is uncertain. We carried out a systematic review of digital actigraphy in patients with depression to investigate the associations between measured physical activity and depression. METHODS: Systematic review and meta-analysis. Studies were identified from Medline, EMBASE and Psycinfo databases and included if they were either case control or longitudinal studies of actigraphy in adults aged between 18 and 65 diagnosed with a depressive disorder. Outcomes were daytime and night-time activity and actigraphic measures of sleep. RESULTS: We identified 19 eligible papers from 16 studies (412 patients). Case control studies showed less daytime activity in patients with depression (standardised mean difference -0.76, 95% confidence intervals -1.05 to -0.47). Longitudinal studies showed moderate increase in daytime activity (0.53, 0.20 to 0.87) and a reduction in night-time activity (-0.36, -0.65 to -0.06) over the course of treatment. LIMITATIONS: All study participants were unblinded. Only seven papers included patients treated in the community. CONCLUSIONS: Actigraphy is a potentially valuable source of additional information about patients with depression. However, there are no clear guidelines for use of actigraphy in studies of patients with depression. Further studies should investigate patients treated in the community. Additional work to develop algorithms for differentiating behaviour patterns is also needed.
Original languageEnglish
Pages (from-to)21-28
Number of pages8
JournalJournal of Affective Disorders
Volume145
Issue number1
Early online date4 Aug 2012
DOIs
Publication statusPublished - 15 Feb 2013

Fingerprint

Physiologic Monitoring
Actigraphy
Depression
Exercise
Longitudinal Studies
Case-Control Studies
Psychomotor Agitation
Depressive Disorder
Meta-Analysis
Sleep
Databases
Guidelines
Confidence Intervals
Equipment and Supplies

Keywords

  • depressive disorder
  • actigraphy
  • telemonitoring

Cite this

Burton, C., McKinstry, B., Szentagotai Tatar, A., Serrano-Blanco, A., Pagliari, C., & Wolters, M. (2013). Activity monitoring in patients with depression: A systematic review. Journal of Affective Disorders, 145(1), 21-28. https://doi.org/10.1016/j.jad.2012.07.001

Activity monitoring in patients with depression : A systematic review. / Burton, Christopher; McKinstry, Brian; Szentagotai Tatar, Aurora; Serrano-Blanco, Antoni; Pagliari, Claudia; Wolters, Maria.

In: Journal of Affective Disorders, Vol. 145, No. 1, 15.02.2013, p. 21-28.

Research output: Contribution to journalArticle

Burton, C, McKinstry, B, Szentagotai Tatar, A, Serrano-Blanco, A, Pagliari, C & Wolters, M 2013, 'Activity monitoring in patients with depression: A systematic review', Journal of Affective Disorders, vol. 145, no. 1, pp. 21-28. https://doi.org/10.1016/j.jad.2012.07.001
Burton C, McKinstry B, Szentagotai Tatar A, Serrano-Blanco A, Pagliari C, Wolters M. Activity monitoring in patients with depression: A systematic review. Journal of Affective Disorders. 2013 Feb 15;145(1):21-28. https://doi.org/10.1016/j.jad.2012.07.001
Burton, Christopher ; McKinstry, Brian ; Szentagotai Tatar, Aurora ; Serrano-Blanco, Antoni ; Pagliari, Claudia ; Wolters, Maria. / Activity monitoring in patients with depression : A systematic review. In: Journal of Affective Disorders. 2013 ; Vol. 145, No. 1. pp. 21-28.
@article{7ff7f2d06e95419ab035581ec8379ff0,
title = "Activity monitoring in patients with depression: A systematic review",
abstract = "BACKGROUND: Altered physical activity is an important feature of depression. It is manifested in psychomotor retardation, agitation and withdrawal from engagement in normal activities. Modern devices for activity monitoring (actigraphs) make it possible to monitor physical activity unobtrusively but the validity of actigraphy as an indicator of mood state is uncertain. We carried out a systematic review of digital actigraphy in patients with depression to investigate the associations between measured physical activity and depression. METHODS: Systematic review and meta-analysis. Studies were identified from Medline, EMBASE and Psycinfo databases and included if they were either case control or longitudinal studies of actigraphy in adults aged between 18 and 65 diagnosed with a depressive disorder. Outcomes were daytime and night-time activity and actigraphic measures of sleep. RESULTS: We identified 19 eligible papers from 16 studies (412 patients). Case control studies showed less daytime activity in patients with depression (standardised mean difference -0.76, 95{\%} confidence intervals -1.05 to -0.47). Longitudinal studies showed moderate increase in daytime activity (0.53, 0.20 to 0.87) and a reduction in night-time activity (-0.36, -0.65 to -0.06) over the course of treatment. LIMITATIONS: All study participants were unblinded. Only seven papers included patients treated in the community. CONCLUSIONS: Actigraphy is a potentially valuable source of additional information about patients with depression. However, there are no clear guidelines for use of actigraphy in studies of patients with depression. Further studies should investigate patients treated in the community. Additional work to develop algorithms for differentiating behaviour patterns is also needed.",
keywords = "depressive disorder, actigraphy, telemonitoring",
author = "Christopher Burton and Brian McKinstry and {Szentagotai Tatar}, Aurora and Antoni Serrano-Blanco and Claudia Pagliari and Maria Wolters",
note = "Copyright {\circledC} 2012 Elsevier B.V. All rights reserved.",
year = "2013",
month = "2",
day = "15",
doi = "10.1016/j.jad.2012.07.001",
language = "English",
volume = "145",
pages = "21--28",
journal = "Journal of Affective Disorders",
issn = "0165-0327",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Activity monitoring in patients with depression

T2 - A systematic review

AU - Burton, Christopher

AU - McKinstry, Brian

AU - Szentagotai Tatar, Aurora

AU - Serrano-Blanco, Antoni

AU - Pagliari, Claudia

AU - Wolters, Maria

N1 - Copyright © 2012 Elsevier B.V. All rights reserved.

PY - 2013/2/15

Y1 - 2013/2/15

N2 - BACKGROUND: Altered physical activity is an important feature of depression. It is manifested in psychomotor retardation, agitation and withdrawal from engagement in normal activities. Modern devices for activity monitoring (actigraphs) make it possible to monitor physical activity unobtrusively but the validity of actigraphy as an indicator of mood state is uncertain. We carried out a systematic review of digital actigraphy in patients with depression to investigate the associations between measured physical activity and depression. METHODS: Systematic review and meta-analysis. Studies were identified from Medline, EMBASE and Psycinfo databases and included if they were either case control or longitudinal studies of actigraphy in adults aged between 18 and 65 diagnosed with a depressive disorder. Outcomes were daytime and night-time activity and actigraphic measures of sleep. RESULTS: We identified 19 eligible papers from 16 studies (412 patients). Case control studies showed less daytime activity in patients with depression (standardised mean difference -0.76, 95% confidence intervals -1.05 to -0.47). Longitudinal studies showed moderate increase in daytime activity (0.53, 0.20 to 0.87) and a reduction in night-time activity (-0.36, -0.65 to -0.06) over the course of treatment. LIMITATIONS: All study participants were unblinded. Only seven papers included patients treated in the community. CONCLUSIONS: Actigraphy is a potentially valuable source of additional information about patients with depression. However, there are no clear guidelines for use of actigraphy in studies of patients with depression. Further studies should investigate patients treated in the community. Additional work to develop algorithms for differentiating behaviour patterns is also needed.

AB - BACKGROUND: Altered physical activity is an important feature of depression. It is manifested in psychomotor retardation, agitation and withdrawal from engagement in normal activities. Modern devices for activity monitoring (actigraphs) make it possible to monitor physical activity unobtrusively but the validity of actigraphy as an indicator of mood state is uncertain. We carried out a systematic review of digital actigraphy in patients with depression to investigate the associations between measured physical activity and depression. METHODS: Systematic review and meta-analysis. Studies were identified from Medline, EMBASE and Psycinfo databases and included if they were either case control or longitudinal studies of actigraphy in adults aged between 18 and 65 diagnosed with a depressive disorder. Outcomes were daytime and night-time activity and actigraphic measures of sleep. RESULTS: We identified 19 eligible papers from 16 studies (412 patients). Case control studies showed less daytime activity in patients with depression (standardised mean difference -0.76, 95% confidence intervals -1.05 to -0.47). Longitudinal studies showed moderate increase in daytime activity (0.53, 0.20 to 0.87) and a reduction in night-time activity (-0.36, -0.65 to -0.06) over the course of treatment. LIMITATIONS: All study participants were unblinded. Only seven papers included patients treated in the community. CONCLUSIONS: Actigraphy is a potentially valuable source of additional information about patients with depression. However, there are no clear guidelines for use of actigraphy in studies of patients with depression. Further studies should investigate patients treated in the community. Additional work to develop algorithms for differentiating behaviour patterns is also needed.

KW - depressive disorder

KW - actigraphy

KW - telemonitoring

U2 - 10.1016/j.jad.2012.07.001

DO - 10.1016/j.jad.2012.07.001

M3 - Article

C2 - 22868056

VL - 145

SP - 21

EP - 28

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

SN - 0165-0327

IS - 1

ER -