Acute stress-induced (takotsubo) cardiomyopathy

Research output: Contribution to journalReview article

30 Citations (Scopus)

Abstract

Acute stress-induced (takotsubo) cardiomyopathy has a dramatic clinical presentation, mimicking an acute myocardial infarction and is triggered by intense emotional or physical stress. In this paper, we review the current state of knowledge of the mechanistic physiology underlying the left ventricular ballooning. The pathophysiology of the recovery from this acute heart failure syndrome is presented. The short-term and long-term outlook puts this new syndrome on a different perspective compared with recently held views. Current knowledge on susceptibility and predisposition already define distinctive characteristics of patients with takotsubo compared with myocardial infarction. Gaps in knowledge and future directions of research are identified in order to best direct efforts for identifying specific therapies for this condition, in the acute setting, to mitigate postacute symptoms or to prevent recurrences, none of which exist.

Original languageEnglish
Pages (from-to)96-102
Number of pages7
JournalHeart
Volume104
Issue number2
Early online date20 Aug 2017
DOIs
Publication statusPublished - 3 Jan 2018

Keywords

  • Journal Article
  • Review

Fingerprint Dive into the research topics of 'Acute stress-induced (takotsubo) cardiomyopathy'. Together they form a unique fingerprint.

  • Cite this