Advanced analytical methodologies to study the microbial metabolome of the human gut

Wendy R. Russell* (Corresponding Author), Sylvia H. Duncan

*Corresponding author for this work

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Emerging evidence suggests that the gut microbiota play an important role in the development of many diseases, including diabetes, cardiovascular disease and cancer. Spectroscopy-based methodologies provide a central, vital tool for the characterization of gut metabolites. This review explores the use and the importance of these techniques to evaluate the microbial metabolome with a particular focus on microbial transformation of dietary protein and fiber.

Original languageEnglish
Pages (from-to)54-60
Number of pages7
JournalTrAC - Trends in Analytical Chemistry
Volume52
Early online date30 Sep 2013
DOIs
Publication statusPublished - Dec 2013

Keywords

  • Aromatic amino acid
  • Dietary fiber
  • Dietary protein
  • Gut health
  • Metabolomics
  • Metagenomics
  • Microbial metabolite
  • Microbiota
  • Short-chain fatty acid
  • Spectroscopy

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