Advances in the development of improved animal-free models for use in breast cancer biomedical research

Sophie Roberts, Valerie Speirs

Research output: Contribution to journalReview article

2 Citations (Scopus)
5 Downloads (Pure)

Abstract

Through translational research, the outcomes for women (and men) diagnosed with breast cancer have improved significantly, with now over 80% of women surviving for at least 5 years post-diagnosis. Much of this success has been translated from the bench to the bedside using laboratory models. Here, we outline the types of laboratory models that have helped achieve this and discuss new approaches as we move towards animal-free disease modelling.

Original languageEnglish
Pages (from-to)321-327
Number of pages7
JournalBiophysical Journal
Volume9
Issue number4
Early online date26 Jul 2017
DOIs
Publication statusPublished - Aug 2017

Keywords

  • Journal Article
  • review
  • breast cancer
  • ex vivo models
  • tissue banks

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