Abstract
Aims To apply established methods to identify ADR-related admissions and to determine the proportion which was preventable and which were caused by non-prescription medicines (NPMs). Methods This prospective, observational study screened all acute hospital admissions (n = 1,101) by ward pharmacists over a 2-week period. Suspected ADR-related admissions were reported to the researcher and established criteria were used to evaluate probability, causality and preventability of the ADR-related admissions. Results Of the 1,101 emergency admissions which occurred during the study period, 30 were categorised as ADR-related, equating to a prevalence of 2.7% (95% CI, 1.8-3.7%). Three (9.7%) of the 30 admissions were associated with NPMs. The ADR was the dominant reason for admission in 56.7% (n = 17/30) and only 13.3% (n = 4/30) of all reported admissions were assessed as unavoidable. Conclusion The proportion of ADR-related admissions was lower than in previous studies in the UK. A substantial proportion of ADRs was associated with NPMs, highlighting the need for greater awareness amongst patients, prescribers and other health care professionals regarding possible serious adverse effects caused by these medicines.
| Original language | English |
|---|---|
| Pages (from-to) | 854-862 |
| Number of pages | 9 |
| Journal | Pharmacy World and Science |
| Volume | 30 |
| Issue number | 6 |
| Early online date | 25 Jul 2008 |
| DOIs | |
| Publication status | Published - Dec 2008 |
Fingerprint
Keywords
- Adverse drug reaction
- Hospital admission
- Non-prescription drug
- OTC medicines
- Prescription medicines
- Scotland
- Prevention
- Unit
Cite this
Adverse-drug-reaction related admissions to a hospital in Scotland. / Hopf, Yvonne; Watson, Margaret; Williams, David.
In: Pharmacy World and Science, Vol. 30, No. 6, 12.2008, p. 854-862.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adverse-drug-reaction related admissions to a hospital in Scotland
AU - Hopf, Yvonne
AU - Watson, Margaret
AU - Williams, David
PY - 2008/12
Y1 - 2008/12
N2 - Aims To apply established methods to identify ADR-related admissions and to determine the proportion which was preventable and which were caused by non-prescription medicines (NPMs). Methods This prospective, observational study screened all acute hospital admissions (n = 1,101) by ward pharmacists over a 2-week period. Suspected ADR-related admissions were reported to the researcher and established criteria were used to evaluate probability, causality and preventability of the ADR-related admissions. Results Of the 1,101 emergency admissions which occurred during the study period, 30 were categorised as ADR-related, equating to a prevalence of 2.7% (95% CI, 1.8-3.7%). Three (9.7%) of the 30 admissions were associated with NPMs. The ADR was the dominant reason for admission in 56.7% (n = 17/30) and only 13.3% (n = 4/30) of all reported admissions were assessed as unavoidable. Conclusion The proportion of ADR-related admissions was lower than in previous studies in the UK. A substantial proportion of ADRs was associated with NPMs, highlighting the need for greater awareness amongst patients, prescribers and other health care professionals regarding possible serious adverse effects caused by these medicines.
AB - Aims To apply established methods to identify ADR-related admissions and to determine the proportion which was preventable and which were caused by non-prescription medicines (NPMs). Methods This prospective, observational study screened all acute hospital admissions (n = 1,101) by ward pharmacists over a 2-week period. Suspected ADR-related admissions were reported to the researcher and established criteria were used to evaluate probability, causality and preventability of the ADR-related admissions. Results Of the 1,101 emergency admissions which occurred during the study period, 30 were categorised as ADR-related, equating to a prevalence of 2.7% (95% CI, 1.8-3.7%). Three (9.7%) of the 30 admissions were associated with NPMs. The ADR was the dominant reason for admission in 56.7% (n = 17/30) and only 13.3% (n = 4/30) of all reported admissions were assessed as unavoidable. Conclusion The proportion of ADR-related admissions was lower than in previous studies in the UK. A substantial proportion of ADRs was associated with NPMs, highlighting the need for greater awareness amongst patients, prescribers and other health care professionals regarding possible serious adverse effects caused by these medicines.
KW - Adverse drug reaction
KW - Hospital admission
KW - Non-prescription drug
KW - OTC medicines
KW - Prescription medicines
KW - Scotland
KW - Prevention
KW - Unit
U2 - 10.1007/s11096-008-9240-5
DO - 10.1007/s11096-008-9240-5
M3 - Article
C2 - 18654836
VL - 30
SP - 854
EP - 862
JO - Pharmacy World and Science
JF - Pharmacy World and Science
SN - 0928-1231
IS - 6
ER -