Alcohol Consumption in Relation to Risk and Severity of Chronic Widespread Pain: Results from a UK population-based study

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Abstract

Objectives: To determine whether reported level of alcohol consumption is associated with the likelihood of reporting chronic widespread pain (CWP) and, amongst persons with CWP, the associated disability.

Methods: A population-based study in two areas of the United Kingdom. Participants self-completed a postal questionnaire. They were classified according to whether they met the American College of Rheumatology definition of CWP and whether the pain was disabling (Chronic Pain Grade III or IV). They reported their usual level of alcohol consumption. Potential confounding factors on which information was available included age, gender, cigarette smoking, employment status, self-reported weight and height and level of deprivation.

Results: 13574 persons participated (mean age 55 years; 57% female) of whom 2239 (16.5%) had CWP: 28% reported never regularly consuming alcohol, 28% consuming up to 5 units/wk, 20% 6-10 units/wk and 24% more than 10 units/wk. Amongst persons with CWP, disability was strongly linked to level of alcohol consumption. Prevalence of disability decreased with increasing alcohol consumption up to 35 unit/wk (Odds Ratio (OR)21-35 units alcohol/wk v. never drinkers 0.33 95% CI (0.19,0.58)) adjusted for confounders. A similar relationship was found between reporting CWP and level of alcohol consumption (adjOR21-35 units alcohol/wk v. regular drinkers 0.76 95% CI (0.61-0.94).

Conclusions: This study has demonstrated strong associations between level of alcohol consumption and CWP . However the available evidence does not allow us to conclude that the association is causal. The strength of the associations means that specific studies to examine this potential relationship are warranted. This article is protected by copyright. All rights reserved.
Original languageEnglish
Pages (from-to)1297-1303
Number of pages7
JournalArthritis Care & Research
Volume67
Issue number9
Early online date20 Jul 2015
DOIs
Publication statusPublished - Sep 2015

Keywords

  • Alcohol
  • Pain
  • Epidemiology

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