Alzheimer patients show a sensitivity decrement over time on a tonic alertness task

M Brazzelli, G Cocchini, S Della Sala, H Spinnler

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Tonic alertness was investigated in Alzheimer patients and normal elderly subjects. Sensitivity and criterion shifts were investigated across 45 min of continuous testing using a high event rate test with very low target probability. Alzheimer patients showed a significant sensitivity decrement over time that was unrelated to dementia severity. These results suggest that tonic alertness is impaired by Alzheimer's disease even in its early stages.

Original languageEnglish
Pages (from-to)851-60
Number of pages10
JournalJournal of Clinical and Experimental Neuropsychology
Volume16
Issue number6
DOIs
Publication statusPublished - Dec 1994

Keywords

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease
  • Attention
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Reaction Time
  • Clinical Trial
  • Comparative Study
  • Journal Article

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