Abstract
Tonic alertness was investigated in Alzheimer patients and normal elderly subjects. Sensitivity and criterion shifts were investigated across 45 min of continuous testing using a high event rate test with very low target probability. Alzheimer patients showed a significant sensitivity decrement over time that was unrelated to dementia severity. These results suggest that tonic alertness is impaired by Alzheimer's disease even in its early stages.
Original language | English |
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Pages (from-to) | 851-60 |
Number of pages | 10 |
Journal | Journal of Clinical and Experimental Neuropsychology |
Volume | 16 |
Issue number | 6 |
DOIs | |
Publication status | Published - Dec 1994 |
Keywords
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Attention
- Female
- Humans
- Male
- Middle Aged
- Neuropsychological Tests
- Reaction Time
- Clinical Trial
- Comparative Study
- Journal Article