Anticancer effects of bioactive berry compounds

Florence Folmer, Umesh Basavaraju, Marcel Jaspars, Georgina Hold, Emad El-Omar, Mario Dicato, Marc Diederich*

*Corresponding author for this work

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

In the present review, we describe chemical and chemopreventive properties as well as health benefits of both extracts and bioactive compounds from various types of berries including small soft-fleshed edible berries and from berry-like fruits such as strawberries, raspberries, blackberries, blueberries, mulberries, currants, gooseberries, elderberries, a double dagger ai berries, and pomegranates. In particular, we describe how berry-derided phytochemicals, including anthocyanidins, proanthocyanidins, flavonols, flavanols, stilbenoids, terpenoids, ellagitannins, and ellagic acid target oxidative and UV radiation stress-induced DNA damage, Helicobacter pilori infection, pro-inflammatory as well as the major cancer hallmarks.

Original languageEnglish
Pages (from-to)295-322
Number of pages28
JournalPhytochemistry reviews
Volume13
Issue number1
Early online date5 Sep 2013
DOIs
Publication statusPublished - 1 Mar 2014

Keywords

  • anthocyanin
  • anti-cancer
  • anti-inflammatory
  • anti-oxidant
  • berry
  • flavonoid
  • NF-Kappa-B
  • colon-cancer cells
  • tumor-necrosis-factor
  • punica-granatum-L.
  • antioxidant capacity
  • prostate-cancer
  • in-vitro
  • black-raspberry
  • TNF-Alpha
  • anthocyanin-rich

Cite this

Folmer, F., Basavaraju, U., Jaspars, M., Hold, G., El-Omar, E., Dicato, M., & Diederich, M. (2014). Anticancer effects of bioactive berry compounds. Phytochemistry reviews, 13(1), 295-322. https://doi.org/10.1007/s11101-013-9319-z