Abstract
Apolipoprotein E (Apo E) epsilon 4 allele is a risk factor for early and late onset Alzheimer's disease. This prompted us to examine other neurophyschiatric phenotypes. Epsilon 4 allele was significantly enriched in Lewy body dementia (N = 39) but not in Parkinson's disease (n = 50) or Schizophrenia (n = 175) compared to aged non-demented controls (n = 47) and the Scottish population (n = 400). We conclude that Lewy body disease should be regarded as a variant of Alzheimer's but not Parkinson's disease.
| Original language | English |
|---|---|
| Pages (from-to) | 161-165 |
| Number of pages | 5 |
| Journal | Journal of Neural Transmission, Supplement |
| Issue number | 51 |
| Publication status | Published - 1 Feb 1997 |
