Assessment of the efficacy, safety and quality of gentamicin use in Aberdeen Royal Infirmary

K O Buabeng, A.r. MacKenzie, R B S Laing, I Cook, B Jappy, I M Gould

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    Abstract

    Fifty-five patients who received od gentamicin were studied. The protocol for od gentamicin was followed in 23/55 (48%). Cure rates were 22/23 (96%) when the protocol was followed and 24/32 (75%) when not followed (P = 0.06). Toxicity was more common in those in whom the protocol was not followed (9/32; 28%) than in those in whom it was followed (1/23; 4%) (P < 0.05). The number needed to treat with the protocol to produce one additional cure was 4.84 (95% CI 2.64 to 28.66) and the number needed to treat to prevent one case of toxicity was 3.61 (95% CI 2.16 to 10.99).

    Original languageEnglish
    Pages (from-to)843-845
    Number of pages3
    JournalJournal of Antimicrobial Chemotherapy
    Volume44
    Publication statusPublished - 1999

    Keywords

    • EDITORIAL RESPONSE
    • AMINOGLYCOSIDES

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